Book contents
- Frontmatter
- Contents
- Abbreviations
- Preface
- 1 Neutrophils and host defence: The fight against infection
- 2 The development and structure of mature neutrophils
- 3 The generation and recognition of neutrophil-activating factors: Structure and function of neutrophil receptors
- 4 The cytoskeleton: The molecular framework regulating cell shape and the traffic of intracellular components
- 5 The respiratory burst: The generation of reactive oxygen metabolites and their role in microbial killing
- 6 Neutrophil activation: The production of intracellular signalling molecules
- 7 Neutrophil priming: Regulation of neutrophil function during inflammatory activation
- 8 Disorders of neutrophil function
- Index
Preface
Published online by Cambridge University Press: 26 February 2010
- Frontmatter
- Contents
- Abbreviations
- Preface
- 1 Neutrophils and host defence: The fight against infection
- 2 The development and structure of mature neutrophils
- 3 The generation and recognition of neutrophil-activating factors: Structure and function of neutrophil receptors
- 4 The cytoskeleton: The molecular framework regulating cell shape and the traffic of intracellular components
- 5 The respiratory burst: The generation of reactive oxygen metabolites and their role in microbial killing
- 6 Neutrophil activation: The production of intracellular signalling molecules
- 7 Neutrophil priming: Regulation of neutrophil function during inflammatory activation
- 8 Disorders of neutrophil function
- Index
Summary
At the end of 1980, when I finished writing a book of the cell division cycle with David Lloyd and Robert Poole, I promised myself that I would never write another. During the past few months there have been many times when I wished that I had kept that promise. During this time I have been reassuring my family, colleagues and not least myself, that it was ‘almost finished’. Now that it finally is complete, I promise that I will never write another. Well, perhaps not for a few years yet.
In writing this text, I have been primarily aiming at a level where new researchers to the field can obtain an overview of many of the exciting new developments in neutrophil biochemistry and physiology. To achieve this, I have kept the number of references to original work to a fairly low number. In doing so, I do not wish to detract from the hundreds or, more correctly, thousands of original publications that have arisen over the past 10 or 20 years. Instead, I have tried to make this an ‘easy read’ and so have only quoted key, landmark references or review articles. I hope that most of the important publications and authors are mentioned, and apologise now if I have offended anyone by not directly quoting their articles. To have included all the interesting and relevant publications in this field would have resulted in a text of over twice this size.
- Type
- Chapter
- Information
- Biochemistry and Physiology of the Neutrophil , pp. xvii - xviiiPublisher: Cambridge University PressPrint publication year: 1994