Book contents
- The Cambridge Handbook of Evolutionary Perspectives on Human Behavior
- The Cambridge Handbook of Evolutionary Perspectives on Human Behavior
- Copyright page
- Dedication
- Contents
- Figures
- Tables
- Contributors
- Preface
- Acknowledgments
- Part I The Comparative Approach
- Part II Sociocultural Anthropology and Evolution
- Part III Evolution and Neuroscience
- Part IV Group Living
- Part V Evolution and Cognition
- Part VI Evolution and Development
- Part VII Sexual Selection and Human Sex Differences
- Part VIII Abnormal Behavior and Evolutionary Psychopathology
- Part IX Applying Evolutionary Principles
- Part X Evolution and the Media
- Index
- References
Part III - Evolution and Neuroscience
Published online by Cambridge University Press: 02 March 2020
Book contents
- The Cambridge Handbook of Evolutionary Perspectives on Human Behavior
- The Cambridge Handbook of Evolutionary Perspectives on Human Behavior
- Copyright page
- Dedication
- Contents
- Figures
- Tables
- Contributors
- Preface
- Acknowledgments
- Part I The Comparative Approach
- Part II Sociocultural Anthropology and Evolution
- Part III Evolution and Neuroscience
- Part IV Group Living
- Part V Evolution and Cognition
- Part VI Evolution and Development
- Part VII Sexual Selection and Human Sex Differences
- Part VIII Abnormal Behavior and Evolutionary Psychopathology
- Part IX Applying Evolutionary Principles
- Part X Evolution and the Media
- Index
- References
Summary
A summary is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
- Type
- Chapter
- Information
- Publisher: Cambridge University PressPrint publication year: 2020
References
References
Cosmides, L., & Tooby, J. (2000). Evolutionary psychology and the emotions. In Lewis, M. & Haviland, J., eds., The Handbook of Emotions, 2nd ed. New York: Guilford, pp. 91–116.Google Scholar
Darwin, C. (1859). On The Origin of Species by Means of Natural Selection, or the Preservation of Favoured Races in the Struggle for Life. London: John Murray.CrossRefGoogle Scholar
Kringelbach, M. L., & Berridge, K. C. (2017). The affective core of emotion: Linking pleasure, subjective well-being and optimal metastability in the brain. Emotion Review, 9, 191–199.CrossRefGoogle ScholarPubMed
Panksepp, J., & Panksepp, J. B. (2000). The seven sins of evolutionary psychology. Evolution and Cognition, 6, 108–131.Google Scholar
Stark, E., Vuust, P., & Kringelbach, M. L. (2018). Music, dance, and other art forms: New insights into the link between hedonia (pleasure) and eudaimonia (well-being). Progress in Brain Research, 237, 129–152.Google Scholar
Toates, F. (2014). How Sexual Desire Works: The Enigmatic Urge. Cambridge, UK: Cambridge University Press.Google Scholar
References
Alexander, B. (2008). The Globalization of Addiction: A Study in Poverty of the Spirit. Oxford: Oxford University Press.Google Scholar
Alexopoulos, G. S., Raue, P. J., Gunning, F., et al. (2016). “Engage” therapy: Behavioral activation and improvement of late-life major depression. American Journal of Geriatric Psychiatry, 24(4), 320–326.CrossRefGoogle ScholarPubMed
Angus, D. J., Schutter, D. J., Terburg, D., et al. (2016). A review of social neuroscience research on anger and aggression. In Harmon-Jones, E. & Inzlicht, M., eds., Social Neuroscience: Biological Approaches to Social Psychology. London: Routledge, pp. 223–246.Google Scholar
Anselme, P. (2013). Dopamine, motivation, and the evolutionary significance of gambling-like behaviour. Behavioural Brain Research, 256, 1–4.Google Scholar
Archer, J. (2004). Sex differences in aggression in real-world settings: A meta-analytic review. Review of General Psychology, 8(4), 291–322.Google Scholar
Archer, J. (2006). Testosterone and human aggression: An evaluation of the challenge hypothesis. Neuroscience & Biobehavioral Reviews, 30(3), 319–345.CrossRefGoogle ScholarPubMed
Archer, J. (2009). The nature of human aggression. International Journal of Law and Psychiatry, 32(4), 202–208.Google Scholar
Baumeister, R. F., & Leary, M. R. (1995). The need to belong: Desire for interpersonal attachments as a fundamental human motivation. Psychological Bulletin, 117(3), 497–529.Google Scholar
Beck, A. T., & Bredemeier, K. (2016). A unified model of depression integrating clinical, cognitive, biological, and evolutionary perspectives. Clinical Psychological Science, 4, 596–619.CrossRefGoogle Scholar
Berkowitz, L., & LePage, A. (1967). Weapons as aggression-eliciting stimuli. Journal of Personality and Social Psychology, 7(2), 202–207.CrossRefGoogle Scholar
Berridge, K. C. (2004). Motivation concepts in behavioral neuroscience. Physiology & Behavior, 81(2), 179–209.CrossRefGoogle ScholarPubMed
Berridge, K. C., & Kringelbach, M. L. (2013). Neuroscience of affect: Brain mechanisms of pleasure and displeasure. Current Opinion in Neurobiology, 23(3), 294–303.CrossRefGoogle ScholarPubMed
Berridge, K. C., & Kringelbach, M. L. (2015). Pleasure systems in the brain. Neuron, 86(3), 646–664.CrossRefGoogle ScholarPubMed
Berridge, K. C., & Valenstein, E. S. (1991). What psychological process mediates feeding evoked by electrical stimulation of the lateral hypothalamus? Behavioral Neuroscience, 105(1), 3–14.Google Scholar
Bindra, D. (1978). How adaptive behavior is produced: A perceptual–motivational alternative to response reinforcements. Behavioral and Brain Sciences, 1(1), 41–52.Google Scholar
Bjorklund, D. F., & Kipp, K. (1996). Parental investment theory and gender differences in the evolution of inhibition mechanisms. Psychological Bulletin, 120(2), 163–188.Google Scholar
Blackburn, J. R., Pfaus, J. G., & Phillips, A. G. (1992). Dopamine functions in appetitive and defensive behaviours. Progress in Neurobiology, 39(3), 247–279.Google Scholar
Blair, R. J. R. (2004). The roles of orbital frontal cortex in the modulation of antisocial behavior. Brain and Cognition, 55(1), 198–208.Google Scholar
Blair, R. J. R. (2016). The neurobiology of impulsive aggression. Journal of Child and Adolescent Psychopharmacology, 26(1), 4–9.Google Scholar
Bolhuis, J. J., Brown, G. R., Richardson, R. C., et al. (2011). Darwin in mind: New opportunities for evolutionary psychology. PLoS Biology, 9(7), e1001109.Google Scholar
Buades-Rotger, M., Brunnlieb, C., Münte, T. F., et al. (2016). Winning is not enough: Ventral striatum connectivity during physical aggression. Brain Imaging and Behavior, 10(1), 105–114.Google Scholar
Buss, D. M. (2016). Evolutionary Psychology: The New Science of the Mind. London: Routledge.Google Scholar
Buss, D. M., & Shackelford, T. K. (1997). Human aggression in evolutionary psychological perspective. Clinical Psychology Review, 17(6), 605–619.CrossRefGoogle ScholarPubMed
Cameron, E. L. (2014). Pregnancy and olfaction: A review. Frontiers in Psychology, 5, 67.CrossRefGoogle ScholarPubMed
Campbell, A. (2013). A Mind of Her Own: The Evolutionary Psychology of Women. Oxford: Oxford University Press.Google Scholar
Carpenter, D., Janssen, E., Graham, C., et al. (2008). Women’s scores on the Sexual Inhibition/Sexual Excitation Scales (SIS/SES): Gender similarities and differences. Journal of Sex Research, 45(1), 36–48.Google Scholar
Carré, J. M., Geniole, S. N., Ortiz, T. L., et al. (2017). Exogenous testosterone rapidly increases aggressive behavior in dominant and impulsive men. Biological Psychiatry, 82(4), 249–256.Google Scholar
Carver, C. S., & Harmon-Jones, E. (2009). Anger is an approach-related affect: Evidence and implications. Psychological Bulletin, 135(2), 183–204.Google Scholar
Carver, C. S., Johnson, S. L., & Joormann, J. (2008). Serotonergic function, two-mode models of self-regulation, and vulnerability to depression: What depression has in common with impulsive aggression. Psychological Bulletin, 134(6), 912–943.Google Scholar
Chevallier, C., Kohls, G., Troiani, V., et al. (2012). The social motivation theory of autism. Trends in Cognitive Sciences, 16(4), 231–239.CrossRefGoogle ScholarPubMed
Chiappe, D., & MacDonald, K. (2005). The evolution of domain-general mechanisms in intelligence and learning. The Journal of General Psychology, 132(1), 5–40.Google Scholar
Cosmides, L., & Tooby, J. (1995). From evolution to adaptations to behavior: Toward an integrated evolutionary psychology. In Wong, R., ed., Biological Perspectives on Motivated Activities. Norwood, NJ: Ablex, pp. 11–74.Google Scholar
Crabb, P. B. (2000). The material culture of homicidal fantasies. Aggressive Behavior, 26(3), 225–234.Google Scholar
Cross, C. P., Copping, L. T., & Campbell, A. (2011). Sex differences in impulsivity: A meta-analysis. Psychological Bulletin, 137(1), 976–130.CrossRefGoogle ScholarPubMed
Davis, C. (2014). Evolutionary and neuropsychological perspectives on addictive behaviors and addictive substances: relevance to the “food addiction” construct. Substance Abuse and Rehabilitation, 5, 129–137.Google Scholar
Daw, N. D., O’Doherty, J. P., Dayan, P., et al. (2006). Cortical substrates for exploratory decisions in humans. Nature, 441(7095), 876–879.CrossRefGoogle ScholarPubMed
Denson, T. F., Schofield, T. P., & Fabiansson, E. C. (2015). Aggressive desires. In Hofmann, W. & Nordgren, L. F., eds., The Psychology of Desire. New York: Guilford Press, pp. 369–389.Google Scholar
De Quervain, D. J., Fischbacher, U., Treyer, V., et al. (2004). The neural basis of altruistic punishment. Science, 305(5688), 1254–1258.Google Scholar
Dreher, J. C., Dunne, S., Pazderska, A., et al. (2016). Testosterone causes both prosocial and antisocial status-enhancing behaviors in human males. Proceedings of the National Academy of Sciences, 113(41), 11633–11638.Google Scholar
Duchaine, B., Cosmides, L., & Tooby, J. (2001). Evolutionary psychology and the brain. Current Opinion in Neurobiology, 11(2), 225–230.Google Scholar
Durisko, Z., Mulsant, B. H., & Andrews, P. W. (2015). An adaptationist perspective on the etiology of depression. Journal of Affective Disorders, 172, 315–323.Google Scholar
Fehr, E., & Camerer, C. F. (2007). Social neuroeconomics: The neural circuitry of social preferences. Trends in Cognitive Sciences, 11(10), 419–427.CrossRefGoogle ScholarPubMed
Gan, G., Preston-Campbell, R. N., Moeller, S. J., et al. (2016). Reward vs. retaliation – The role of the mesocorticolimbic salience network in human reactive aggression. Frontiers in Behavioral Neuroscience, 10, 179.Google Scholar
Gard, D. E., Kring, A. M., Gard, M. G., et al. (2007). Anhedonia in schizophrenia: distinctions between anticipatory and consummatory pleasure. Schizophrenia Research, 93(1), 253–260.Google Scholar
Glenn, A. L., & Raine, A. (2009). Psychopathy and instrumental aggression: Evolutionary, neurobiological, and legal perspectives. International Journal of Law and Psychiatry, 32(4), 253–258.Google Scholar
Groppe, S. E., Gossen, A., Rademacher, L., et al. (2013). Oxytocin influences processing of socially relevant cues in the ventral tegmental area of the human brain. Biological Psychiatry, 74(3), 172–179.CrossRefGoogle ScholarPubMed
Gunaydin, L. A., & Deisseroth, K. (2014). Dopaminergic dynamics contributing to social behavior. Cold Spring Harbor Symposia on Quantitative Biology, 79, 221–227.Google Scholar
Hart, B. L. (1988). Biological basis of the behavior of sick animals. Neuroscience and Biobehavioral Reviews, 12(2), 123–137.Google Scholar
Hartlage, S., Alloy, L. B., Vázquez, C., et al. (1993). Automatic and effortful processing in depression. Psychological Bulletin, 113(2), 247–278.CrossRefGoogle ScholarPubMed
Hein, G., Engelmann, J. B., Vollberg, M. C., et al. (2016). How learning shapes the empathic brain. Proceedings of the National Academy of Sciences, 113(1), 80–85.Google Scholar
Itoga, C. A., Berridge, K. C., & Aldridge, J. W. (2016). Ventral pallidal coding of a learned taste aversion. Behavioural Brain Research, 300, 175–183.CrossRefGoogle ScholarPubMed
Jepma, M., Verdonschot, R. G., Van Steenbergen, H., et al. (2012). Neural mechanisms underlying the induction and relief of perceptual curiosity. Frontiers in Behavioral Neuroscience, 6, 5.Google Scholar
Johnson, S. L., Edge, M. D., Holmes, M. K., et al. (2012). The behavioral activation system and mania. Annual Review of Clinical Psychology, 8, 243–267.Google Scholar
Kim, P., Strathearn, L., & Swain, J. E. (2016). The maternal brain and its plasticity in humans. Hormones and Behavior, 77, 113–123.Google Scholar
Kohls, G., Perino, M. T., Taylor, J. M., et al. (2013). The nucleus accumbens is involved in both the pursuit of social reward and the avoidance of social punishment. Neuropsychologia, 51(11), 2062–2069.Google Scholar
Krebs, J. R., & Davies, N. B. (1978). Behavioural Ecology: An Evolutionary Approach. Oxford: Blackwell Science.Google Scholar
Kringelbach, M. L., Lehtonen, A., Squire, S., et al. (2008). A specific and rapid neural signature for parental instinct. PLoS ONE, 3(2), e1664.Google Scholar
Lambert, K. G. (2006). Rising rates of depression in today’s society: Consideration of the roles of effort-based rewards and enhanced resilience in day-to-day functioning. Neuroscience and Biobehavioral Reviews, 30(4), 497–510.CrossRefGoogle ScholarPubMed
Litman, J. (2005). Curiosity and the pleasures of learning: Wanting and liking new information. Cognition and Emotion, 19(6), 793–814.Google Scholar
Lopez, R. B., Wagner, D. D., & Heatherton, T. F. (2015). Neuroscience of desire regulation. In Hofmann, W. & Nordgren, L. F., eds., The Psychology of Desire. New York: Guilford Press, pp. 146–160.Google Scholar
MacDonald, G., & Leary, M. R. (2005). Why does social exclusion hurt? The relationship between social and physical pain. Psychological Bulletin, 131(2), 202–223.CrossRefGoogle ScholarPubMed
Mazur, A., & Booth, A. (1998). Testosterone and dominance in men. Behavioral and Brain Sciences, 21(3), 353–363.Google Scholar
Nesse, R. M. (2001). Motivation and melancholy: A Darwinian perspective. Nebraska Symposium on Motivation, 47, 179–203.Google ScholarPubMed
Nesse, R. M., & Berridge, K. C. (1997). Psychoactive drug use in evolutionary perspective. Science, 278(5335), 63–66.CrossRefGoogle ScholarPubMed
Nettle, D. (2004). Evolutionary origins of depression: A review and reformulation. Journal of Affective Disorders, 81(2), 91–102.CrossRefGoogle ScholarPubMed
Over, H. (2016). The origins of belonging: social motivation in infants and young children. Philosophical Transactions of the Royal Society B, 371(1686), 20150072.Google Scholar
Panksepp, J. (1998). Affective Neuroscience: The Foundations of Human and Animal Emotions. Oxford: Oxford University Press.Google Scholar
Panksepp, J. (2014). Seeking and loss in the ancestral genesis of resilience, depression, and addiction. In Kent, M, Davis, M. C, & Reich, J. W, eds., The Resilience Handbook: Approaches to Stress and Trauma. New York: Routledge, pp. 3–14.Google Scholar
Panksepp, J., & Panksepp, J. B. (2000). The seven sins of evolutionary psychology. Evolution and Cognition, 6(2), 108–131.Google Scholar
Papageorgiou, G. K., Baudonnat, M., Cucca, F., et al. (2016). Mesolimbic dopamine encodes prediction errors in a state-dependent manner. Cell Reports, 15(2), 221–228.CrossRefGoogle Scholar
Patil, C. L., Abrams, E. T., Steinmetz, A. R., et al. (2012). Appetite sensations and nausea and vomiting in pregnancy: An overview of the explanations. Ecology of Food and Nutrition, 51(5), 394–417.CrossRefGoogle ScholarPubMed
Pinker, S. (2011). The Better Angels of our Nature: The Decline of Violence in History and its Causes. London: Penguin.Google Scholar
Price, J., Sloman, L., Gardner, R., et al. (1994). The social competition hypothesis of depression. British Journal of Psychiatry, 164(3), 309–315.Google Scholar
Profet, M. (1992) Pregnancy sickness as adaptation: A deterrent to maternal ingestion of teratogens. In Barkow, J. H., Cosmides, L., & Tooby, J., eds., The Adapted Mind: Evolutionary Psychology and the Generation of Culture. New York: Oxford University Press, pp. 327–365.CrossRefGoogle Scholar
Radke, S., Seidel, E. M., Eickhoff, S. B., et al. (2016). When opportunity meets motivation: Neural engagement during social approach is linked to high approach motivation. NeuroImage, 127, 267–276.Google Scholar
Raichlen, D. A., Foster, A. D., Seillier, A., et al. (2013). Exercise-induced endocannabinoid signaling is modulated by intensity. European Journal of Applied Physiology, 113(4), 869–875.Google Scholar
Ramírez, J. M., Bonniot-Cabanac, M. C., & Cabanac, M. (2005). Can impulsive aggression provide pleasure? European Psychologist, 10(2), 136–145.Google Scholar
Ray, W. J. (2013). Evolutionary psychology: Neuroscience Perspectives Concerning Human Behavior and Experience. Los Angeles, CA: Sage.Google Scholar
Robinson, T. E., & Berridge, K. C. (1993). The neural basis of drug craving: An incentive-sensitization theory of addiction. Brain Research Reviews, 18(3), 247–291.Google Scholar
Rolls, E. T., Murzi, E., Yaxley, S., et al. (1986). Sensory-specific satiety: Food-specific reduction in responsiveness of ventral forebrain neurons after feeding in the monkey. Brain Research, 368(1), 79–86.Google Scholar
Rosell, D. R., & Siever, L. J. (2015). The neurobiology of aggression and violence. CNS Spectrums, 20(3), 254–279.Google Scholar
Rupp, H. A., James, T. W., Ketterson, E. D., et al. (2009). The role of the anterior cingulate cortex in women’s sexual decision making. Neuroscience Letters, 449(1), 42–47.Google Scholar
Salamone, J. D., Correa, M., Farrar, A., et al. (2007). Effort-related functions of nucleus accumbens dopamine and associated forebrain circuits. Psychopharmacology, 191(3), 461–482.Google Scholar
Schulkin, J. (2016). Evolutionary basis of human running and its impact on neural function. Frontiers in Systems Neuroscience, 10, 59.Google Scholar
Spreckelmeyer, K. N., Krach, S., Kohls, G., et al. (2009). Anticipation of monetary and social reward differently activates mesolimbic brain structures in men and women. Social Cognitive and Affective Neuroscience, 4(2), 158–165.Google Scholar
Stice, E., & Yokum, S. (2016). Neural vulnerability factors that increase risk for future weight gain. Psychological Bulletin, 142(5), 447–471.Google Scholar
Stockhorst, U., Enck, P., & Klosterhalfen, S. (2007). Role of classical conditioning in learning gastrointestinal symptoms. World Journal of Gastroenterology, 13(25), 3430–3437.Google Scholar
Temple, J. L. (2016). Behavioral sensitization of the reinforcing value of food: What food and drugs have in common. Preventive Medicine, 92, 90–99.CrossRefGoogle ScholarPubMed
Toates, F. (1998). The interaction of cognitive and stimulus–response processes in the control of behaviour. Neuroscience & Biobehavioral Reviews, 22(1), 59–83.Google Scholar
Toates, F. (2005). Evolutionary psychology – Towards a more integrative model. Biology and Philosophy, 20(2–3), 305–328.Google Scholar
Toates, F. (2014). How Sexual Desire Works: The Enigmatic Urge. Cambridge, UK: Cambridge University Press.Google Scholar
Toates, F. M., & Archer, J. (1978). A comparative review of motivational systems using classical control theory. Animal Behaviour, 26, 368–380.Google Scholar
Treadway, M. T. (2015). Liking little, wanting less. In Hofmann, W. & Nordgren, L. F., eds., The Psychology of Desire. New York: Guilford Press, pp. 307–320.Google Scholar
Wagner, D. D., & Heatherton, T. F. (2015). Self-regulation and its failure: The seven deadly threats to self-regulation. In Mikulincer, M. & Shaver, P.R., eds., APA Handbook of Personality and Social Psychology: Vol. 1. Attitudes and Social Cognition. Washington, DC: American Psychological Association, pp. 805–842.Google Scholar
White, S. F., Brislin, S. J., Sinclair, S., et al. (2014). Punishing unfairness: Rewarding or the organization of a reactively aggressive response? Human Brain Mapping, 35(5), 2137–2147.Google Scholar
Wittmann, B. C., Daw, N. D., Seymour, B., et al. (2008). Striatal activity underlies novelty-based choice in humans. Neuron, 58(6), 967–973.Google Scholar
Wittman, D. (2014). Darwinian depression. Journal of Affective Disorders, 168, 142–150.Google Scholar
Wondra, J. D., & Ellsworth, P. C. (2015). An appraisal theory of empathy and other vicarious emotional experiences. Psychological Review, 122(3), 411–428.Google Scholar
Zeeland, S. V., Ashley, A., Dapretto, M., et al. (2010). Reward processing in autism. Autism Research, 3(2), 53–67.Google Scholar
References
(350 BCE/1976). The Nicomachean Ethics, Book 10, trans. by Thomson, J. A. K.. London: Penguin Books.Google Scholar
Berridge, K. C. (1996). Food reward: Brain substrates of wanting and liking. Neuroscience and Biobehavioral Reviews, 20, 1–25.Google Scholar
Berridge, K. C. (2000). Measuring hedonic impact in animals and infants: Microstructure of affective taste reactivity patterns. Neuroscience and Biobehavioral Reviews, 24, 173–198.Google Scholar
Berridge, K. C. (2007). Brain reward systems for food incentives and hedonics in normal appetite and eating disorders. In Kirkham, T. C & Cooper, S. J, eds., Appetite and Body Weight. New York: Academic Press, pp. 191–216Google Scholar
Berridge, K. C., & Kringelbach, M. L. (2008). Affective neuroscience of pleasure: Reward in humans and animals. Psychopharmacology, 199, 457–480.CrossRefGoogle ScholarPubMed
Berridge, K. C., & Kringelbach, M. L. (2011). Building a neuroscience of pleasure and well-being. Psychology of Well-Being, 1(1), 1–3.Google Scholar
Berridge, K. C., & Kringelbach, M. L. (2015). Pleasure systems in the brain. Neuron, 86, 646–664.Google Scholar
Berridge, K. C., & Robinson, T. E. (2003). Parsing reward. Trends in Neurosciences, 26, 507–513.CrossRefGoogle ScholarPubMed
Biswal, B., Yetkin, F., Haughton, V., & Hyde, J. (1995). Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magnetic Resonance in Medicine, 34, 537–541.Google Scholar
Cabanac, M., & Lafrance, L. (1990). Postingestive alliesthesia: The rat tells the same story. Physiology and Behavior, 47, 539–543.Google Scholar
Cabral, J., Kringelbach, M. L., & Deco, G. (2014). Exploring the network dynamics underlying brain activity during rest. Progress in Neurobiology, 114, 102–131.CrossRefGoogle Scholar
Castro, D. C., & Berridge, K. C. (2017). Opioid and orexin hedonic hotspots in rat orbitofrontal cortex and insula. Proceedings of the National Academy of Sciences, 114, E9125–E9134.Google Scholar
Cavanna, A. E., & Trimble, M. R. (2006). The precuneus: A review of its functional anatomy and behavioural correlates. Brain, 129, 564–583.Google Scholar
Crisp, R., & Kringelbach, M. L. (2018). Higher and lower pleasures revisited: Evidence from neuroscience. Neuroethics, 11, 211–215.Google Scholar
Diener, E., Lucas, R. E., & Scollon, C. N. (2006). Beyond the hedonic treadmill: Revising the adaptation theory of well-being. American Psychologist, 61, 305–314.Google Scholar
Drevets, W. C., Price, J. L., Simpson, J. R. Jr., et al. (1997). Subgenual prefrontal cortex abnormalities in mood disorders. Nature, 386, 824–827.Google Scholar
Fervaha, G., Graff-Guerrero, A., Zakzanis, K. K., et al. (2013). Incentive motivation deficits in schizophrenia reflect effort computation impairments during cost–benefit decision-making. Journal of Psychiatric Research, 47, 1590–1596.Google Scholar
Frijda, N. (2010). On the nature and function of pleasure. In Kringelbach, M. L. & Berridge, K. C, eds., Pleasures of the Brain. New York: Oxford University Press, pp. 99–112.Google Scholar
Gold, J. M., Strauss, G. P., Waltz, J. A., et al. (2013). Negative symptoms of schizophrenia are associated with abnormal effort-cost computations. Biological Psychiatry, 74, 130–136.Google Scholar
Grill, H. J., & Norgren, R. (1978). The taste reactivity test. I. Mimetic responses to gustatory stimuli in neurologically normal rats. Brain Research, 143, 263–279.Google Scholar
Gusnard, D. A., & Raichle, M. E. (2001). Searching for a baseline: Functional imaging and the resting human brain. Nature Reviews Neuroscience, 2, 685–694.Google Scholar
Kahneman, D. (1999). Objective happiness. In Kahneman, D., Diener, E., & Schwartz, N., eds., Well-being: The Foundation of Hedonic Psychology. New York: Russell Sage Foundation, pp. 3–25.Google Scholar
Kaplan, J. M., Roitman, M., & Grill, H. J. (2000). Food deprivation does not potentiate glucose taste reactivity responses of chronic decerebrate rats. Brain Research, 870, 102–108.Google Scholar
Kringelbach, M. L. (2004a). Emotion. In Gregory, R. L, ed., The Oxford Companion to the Mind, 2nd ed. Oxford: Oxford University Press, pp. 287–290.Google Scholar
Kringelbach, M. L. (2005a). The human orbitofrontal cortex: linking reward to hedonic experience. Nature Reviews Neuroscience, 6, 691–702.Google Scholar
Kringelbach, M. L. (2005b). The orbitofrontal cortex: Linking reward to hedonic experience. Nature Reviews Neuroscience, 6, 691–702.Google Scholar
Kringelbach, M. L. (2009). The Pleasure Center: Trust Your Animal Instincts. New York: Oxford University Press.Google Scholar
Kringelbach, M. L. (2010). The hedonic brain: A functional neuroanatomy of human pleasure. In Kringelbach, M. L. & Berridge, K. C, eds., Pleasures of the Brain. Oxford: Oxford University Press, pp. 202–221.Google Scholar
Kringelbach, M. L., & Berridge, K. C. (2009). Towards a functional neuroanatomy of pleasure and happiness in the brain. Trends in Cognitive Sciences, 13, 479–487.Google Scholar
Kringelbach, M. L., & Berridge, K. C. (2017). The affective core of emotion: linking pleasure, subjective well-being and optimal metastability in the brain. Emotion Review, 9, 191–199.Google Scholar
Kringelbach, M. L., & Rolls, E. T. (2004). The functional neuroanatomy of the human orbitofrontal cortex: Evidence from neuroimaging and neuropsychology. Progress in Neurobiology, 72, 341–372.Google Scholar
Kringelbach, M. L., McIntosh, A. R., Ritter, P., Jirsa, V. K., & Deco, G. (2015). The rediscovery of slowness: Exploring the timing of cognition. Trends in Cognitive Sciences, 19, 616–628.Google Scholar
Lou, H. C., Kjaer, T. W., Friberg, L., et al. (1999). A 15O–H2O PET study of meditation and the resting state of normal consciousness. Human Brain Mapping, 7, 98–105.Google Scholar
McFarland, B. R., & Klein, D. N. (2009). Emotional reactivity in depression: Diminished responsiveness to anticipated reward but not to anticipated punishment or to nonreward or avoidance. Depression and Anxiety, 26, 117–122.Google Scholar
O’Doherty, J., Rolls, E. T., Francis, S., Bowtell, R., & McGlone, F. (2001). Representation of pleasant and aversive taste in the human brain. Journal of Neurophysiology, 85, 1315–1321.Google Scholar
Pizzagalli, D. A., Iosifescu, D., Hallett, L. A., Ratner, K. G., & Fava, M. (2008). Reduced hedonic capacity in major depressive disorder: Evidence from a probabilistic reward task. Journal of Psychiatric Research, 43, 76–87.Google Scholar
Rømer Thomsen, K., Whybrow, P. C., & Kringelbach, M. L. (2015). Reconceptualising anhedonia: Novel perspectives on balancing the pleasure networks in the human brain. Frontiers in Behavioral Neuroscience, 9, 49.Google Scholar
Sato, W., Kochiyama, T., Uono, S., et al. (2015). The structural neural substrate of subjective happiness. Scientific Reports, 5, 16891.Google Scholar
Seligman, M. E., Steen, T. A., Park, N., & Peterson, C. (2005). Positive psychology progress: Empirical validation of interventions. American Psychologist, 60, 410–421.Google Scholar
Smith, K. S., Mahler, S. V., Pecina, S., & Berridge, K. C. (2010). Hedonic hotspots: Generating sensory pleasure in the brain. In Kringelbach, M. L & Berridge, K. C, eds., Pleasures of the Brain. New York: Oxford University Press, pp. 27–49.Google Scholar
Steiner, J. E. (1973). The gustofacial response: Observation on normal and anencephalic newborn infants. Symposium on Oral Sensation and Perception, 4, 254–278.Google Scholar
Steiner, J. E., Glaser, D., Hawilo, M. E., & Berridge, K. C. (2001). Comparative expression of hedonic impact: Affective reactions to taste by human infants and other primates. Neuroscience and Biobehavioral Reviews, 25, 53–74.Google Scholar
Strauss, G. P., & Gold, J. M. (2012). A new perspective on anhedonia in schizophrenia. American Journal of Psychiatry, 169, 364–373.CrossRefGoogle ScholarPubMed
Treadway, M. T., Bossaller, N. A., Shelton, R. C., & Zald, D. H. (2012). Effort-based decision-making in major depressive disorder: a translational model of motivational anhedonia. Journal of Abnormal Psychology, 121, 553–558.Google Scholar
Waltz, J. A., Frank, M. J., Robinson, B. M., & Gold, J. M. (2007). Selective reinforcement learning deficits in schizophrenia support predictions from computational models of striatal–cortical dysfunction. Biological Psychiatry, 62, 756–764.Google Scholar
Watson, D., & Naragon-Gainey, K. (2010). On the specificity of positive emotional dysfunction in psychopathology: Evidence from the mood and anxiety disorders and schizophrenia/schizotypy. Clinical Psychology Review, 30, 839–848.Google Scholar
Whybrow, P. C. (1998). A Mood Apart: The Thinkers Guide to Emotion and its Disorder. New York: Harper Perennial.Google Scholar
Yang, X. H., Huang, J., Zhu, C. Y., et al. (2014). Motivational deficits in effort-based decision making in individuals with subsyndromal depression, first-episode and remitted depression patients. Psychiatry Research, 220, 874–882.Google Scholar
References
Abel, T., & Zukin, R. S. (2008). Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders. Current Opinion in Pharmacology, 8, 57–64.Google Scholar
Adhya, D., Swarup, V., Nowosiad, P., et al. (2018). Shared gene co-expression networks in autism from induced pluripotent stem cell (iPSC) neurons. bioRxiv, doi.org/10.1101/349415.Google Scholar
Amenduni, M., De Filippis, R., Cheung, A. Y., et al. (2011). iPS cells to model CDKL5-related disorders. European Journal of Human Genetics, 19, 1246–1255.Google Scholar
Ananiev, G., Williams, E. C., Li, H., & Chang, Q. (2011). Isogenic pairs of wild type and mutant induced pluripotent stem cell (iPSC) lines from Rett syndrome patients as in vitro disease model. PLoS ONE, 6, e25255.Google Scholar
Angoa-Perez, M., Jiang, H., Rodriguez, A. I., et al. (2006). Estrogen counteracts ozone-induced oxidative stress and nigral neuronal death. Neuroreport, 17, 629–633.Google Scholar
APA (2013). Diagnostic and Statistical Manual of Mental Disorders (DSM-5®). Washington, DC: American Psychiatric Association Publishing.Google Scholar
Araneda, S., Commin, L., Atlagich, M., et al. (2008). VEGF overexpression in the astroglial cells of rat brainstem following ozone exposure. Neurotoxicology, 29, 920–927.Google Scholar
Arentsen, T., Raith, H., Qian, Y., Forssberg, H., & Diaz Heijtz, R. (2015). Host microbiota modulates development of social preference in mice. Microbial Ecology in Health and Disease, 26, 29719.Google Scholar
Audouze, K., & Grandjean, P. (2011). Application of computational systems biology to explore environmental toxicity hazards. Environmental Health Perspectives, 119, 1754–1759.Google Scholar
Bakulski, K. M., Halladay, A., Hu, V. W., Mill, J., & Fallin, M. D. (2016). Epigenetic research in neuropsychiatric disorders: The “tissue issue”. Current Behavioral Neuroscience Reports, 3, 264–274.Google Scholar
Bal, W., Liang, R., Lukszo, J., et al. (2000). Ni(II) specifically cleaves the C-terminal tail of the major variant of histone H2A and forms an oxidative damage-mediating complex with the cleaved-off octapeptide. Chemical Research in Toxicology, 13, 616–624.Google Scholar
Bao, A. M., & Swaab, D. F. (2011). Sexual differentiation of the human brain: relation to gender identity, sexual orientation and neuropsychiatric disorders. Frontiers in Neuroendocrinology, 32, 214–226.Google Scholar
Bar-Nur, O., Caspi, I., & Benvenisty, N. (2012). Molecular analysis of FMR1 reactivation in fragile-X induced pluripotent stem cells and their neuronal derivatives. Journal of Molecular Cell Biology, 4, 180–183.Google Scholar
Baron-Cohen, S., Lombardo, M. V., Auyeung, B., et al. (2011). Why are autism spectrum conditions more prevalent in males? PLoS Biology, 9, e1001081.Google Scholar
Baron-Cohen, S., Auyeung, B., Norgaard-Pedersen, B., et al. (2015). Elevated fetal steroidogenic activity in autism. Molecular Psychiatry, 20, 369–376.Google Scholar
Basu, S. N., Kollu, R., & Banerjee-Basu, S. (2009). AutDB: A gene reference resource for autism research. Nucleic Acids Researchearch, 37, D832–D836.Google Scholar
Becerra, T. A., Wilhelm, M., Olsen, J., Cockburn, M., & Ritz, B. (2013). Ambient air pollution and autism in Los Angeles County, California. Environmental Health Perspectives, 121, 380–386.Google Scholar
Bellavia, A., Urch, B., Speck, M., et al. (2013). DNA hypomethylation, ambient particulate matter, and increased blood pressure: findings from controlled human exposure experiments. Journal of the American Heart Association, 2, e000212.Google Scholar
Belton, J. M., McCord, R. P., Gibcus, J. H., et al. (2012). Hi-C: A comprehensive technique to capture the conformation of genomes. Methods, 58, 268–276.Google Scholar
Berger, S. L., Kouzarides, T., Shiekhattar, R., & Shilatifard, A. (2009). An operational definition of epigenetics. Genes & Development, 23, 781–783.Google Scholar
Blanchard, K. S., Palmer, R. F., & Stein, Z. (2011). The value of ecologic studies: Mercury concentration in ambient air and the risk of autism. Reviews in Environmental Health, 26, 111–118.Google Scholar
Block, M. L., & Calderon-Garciduenas, L. (2009). Air pollution: Mechanisms of neuroinflammation and CNS disease. Trends in Neurosciences, 32, 506–516.Google Scholar
Bollati, V., & Baccarelli, A. (2010). Environmental epigenetics. Heredity, 105, 105–112.Google Scholar
Borochov, N., Ausio, J., & Eisenberg, H. (1984). Interaction and conformational changes of chromatin with divalent ions. Nucleic Acids Research, 12, 3089–3096.Google Scholar
Bourassa, M. W., Alim, I., Bultman, S. J., & Ratan, R. R. (2016). Butyrate, neuroepigenetics and the gut microbiome: Can a high fiber diet improve brain health? Neuroscience Letters, 625, 56–63.Google Scholar
Bourgeron, T. (2015). From the genetic architecture to synaptic plasticity in autism spectrum disorder. Nature Reviews Neuroscience, 16, 551–563.Google Scholar
Bravo, J. A., Forsythe, P., Chew, M. V., et al. (2011). Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proceedings of the National Academy of Sciences, 108, 16050–16055.Google Scholar
Breton, C. V., Salam, M. T., Wang, X., et al. (2012). Particulate matter, DNA methylation in nitric oxide synthase, and childhood respiratory disease. Environmental Health Perspectives, 120, 1320–1326.CrossRefGoogle ScholarPubMed
Buenrostro, J. D., Giresi, P. G., Zaba, L. C., Chang, H. Y., & Greenleaf, W. J. (2013). Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. Nature Methods, 10, 1213–1218.Google Scholar
Byrum, S. D., Raman, A., Taverna, S. D., & Tackett, A. J. (2012). ChAP-MS: A method for identification of proteins and histone posttranslational modifications at a single genomic locus. Cell Reports, 2, 198–205.Google Scholar
Calderon-Garciduenas, L., Mora-Tiscareno, A., Ontiveros, E., et al. (2008a). Air pollution, cognitive deficits and brain abnormalities: A pilot study with children and dogs. Brain and Cognition, 68, 117–127.Google Scholar
Calderon-Garciduenas, L., Solt, A. C., Henriquez-Roldan, C., et al. (2008b). Long-term air pollution exposure is associated with neuroinflammation, an altered innate immune response, disruption of the blood–brain barrier, ultrafine particulate deposition, and accumulation of amyloid beta-42 and alpha-synuclein in children and young adults. Toxicologic Pathology, 36, 289–310.Google Scholar
Carroll, S. B. (2008). Evo-devo and an expanding evolutionary synthesis: a genetic theory of morphological evolution. Cell, 134, 25–36.Google Scholar
Castel, S. E., & Martienssen, R. A. (2013). RNA interference in the nucleus: Roles for small RNAs in transcription, epigenetics and beyond. Nature Reviews Genetics, 14, 100–112.Google Scholar
Chaidez, V., Hansen, R. L., & Hertz-Picciotto, I. (2014). Gastrointestinal problems in children with autism, developmental delays or typical development. Journal of Autism and Developmental Disorders, 44, 1117–1127.Google Scholar
Chambers, S. M., Fasano, C. A., Papapetrou, E. P., et al. (2009). Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nature Biotechnology, 27, 275–280.Google Scholar
Chen, H., Ke, Q., Kluz, T., Yan, Y., & Costa, M. (2006). Nickel ions increase histone H3 lysine 9 dimethylation and induce transgene silencing. Molecular and Cellular Biology, 26, 3728–3737.Google Scholar
Cheung, A. Y., Horvath, L. M., Grafodatskaya, D., et al. (2011). Isolation of MECP2-null Rett syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation. Human Molecular Genetics, 20, 2103–2115.Google Scholar
Choi, G. B., Yim, Y. S., Wong, H., et al. (2016). The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring. Science, 351, 933–939.Google Scholar
Clarke, G., O’Mahony, S. M., Dinan, T. G., & Cryan, J. F. (2014). Priming for health: Gut microbiota acquired in early life regulates physiology, brain and behaviour. Acta Paediatrica, 103, 812–819.CrossRefGoogle ScholarPubMed
Coiro, P., Padmashri, R., Suresh, A., et al. (2015). Impaired synaptic development in a maternal immune activation mouse model of neurodevelopmental disorders. Brain, Behavior, and Immunity, 50, 249–258.Google Scholar
Coleman, M. (1976). The Autistic Syndromes. Amsterdam: North-Holland Publishing Company.Google Scholar
Cooper, G. S., Martin, S. A., Longnecker, M. P., Sandler, D. P., & Germolec, D. R. (2004). Associations between plasma DDE levels and immunologic measures in African-American farmers in North Carolina. Environmental Health Perspectives, 112, 1080–1084.Google Scholar
Corsini, E., Liesivuori, J., Vergieva, T., Van Loveren, H., & Colosio, C. (2008). Effects of pesticide exposure on the human immune system. Human & Experimental Toxicology, 27, 671–680.Google Scholar
Corsini, E., Sokooti, M., Galli, C. L., Moretto, A., & Colosio, C. (2013). Pesticide induced immunotoxicity in humans: A comprehensive review of the existing evidence. Toxicology, 307, 123–135.Google Scholar
Crumeyrolle-Arias, M., Jaglin, M., Bruneau, A., et al. (2014). Absence of the gut microbiota enhances anxiety-like behavior and neuroendocrine response to acute stress in rats. Psychoneuroendocrinology, 42, 207–217.Google Scholar
Dally, H., & Hartwig, A. (1997). Induction and repair inhibition of oxidative DNA damage by nickel(II) and cadmium(II) in mammalian cells. Carcinogenesis, 18, 1021–1026.Google Scholar
Davies, J. O., Oudelaar, A. M., Higgs, D. R., & Hughes, J. R. (2017). How best to identify chromosomal interactions: A comparison of approaches. Nature Methods, 14, 125–134.Google Scholar
de Theije, C. G., Koelink, P. J., Korte-Bouws, G. A., et al. (2014a). Intestinal inflammation in a murine model of autism spectrum disorders. Brain, Behavior, and Immunity, 37, 240–247.Google Scholar
de Theije, C. G., Wopereis, H., Ramadan, M., et al. (2014b). Altered gut microbiota and activity in a murine model of autism spectrum disorders. Brain, Behavior, and Immunity, 37, 197–206.Google Scholar
De Vadder, F., Kovatcheva-Datchary, P., Goncalves, D., et al. (2014). Microbiota-generated metabolites promote metabolic benefits via gut–brain neural circuits. Cell, 156, 84–96.Google Scholar
Dekker, J., Rippe, K., Dekker, M., & Kleckner, N. (2002). Capturing chromosome conformation. Science, 295, 1306–1311.Google Scholar
DeRosa, B. A., Van Baaren, J. M., Dubey, G. K., et al. (2012). Derivation of autism spectrum disorder-specific induced pluripotent stem cells from peripheral blood mononuclear cells. Neuroscience Letters, 516, 9–14.Google Scholar
Desaulniers, D., Xiao, G. H., Lian, H., et al. (2009). Effects of mixtures of polychlorinated biphenyls, methylmercury, and organochlorine pesticides on hepatic DNA methylation in prepubertal female Sprague-Dawley rats. International Journal of Toxicology, 28, 294–307.Google Scholar
Desbonnet, L., Clarke, G., Shanahan, F., Dinan, T. G., & Cryan, J. F. (2014). Microbiota is essential for social development in the mouse. Molecular Psychiatry, 19, 146–148.Google Scholar
Diaz Heijtz, R., Wang, S., Anuar, F., et al. (2011). Normal gut microbiota modulates brain development and behavior. Proceedings of the National Academy of Sciences, 108, 3047–3052.Google Scholar
Ding, H. T., Taur, Y., & Walkup, J. T. (2017). Gut microbiota and autism: Key concepts and findings. Journal of Autism and Developmental Disorders, 47, 480–489.Google Scholar
Doi, T., Puri, P., McCann, A., Bannigan, J., & Thompson, J. (2011). Epigenetic effect of cadmium on global de novo DNA hypomethylation in the cadmium-induced ventral body wall defect (VBWD) in the chick model. Toxicological Sciences, 120, 475–480.Google Scholar
El-Ansary, A., & Al-Ayadhi, L. (2014). GABAergic/glutamatergic imbalance relative to excessive neuroinflammation in autism spectrum disorders. Journal of Neuroinflammation, 11, 189.Google Scholar
Emanuele, E., Orsi, P., Boso, M., et al. (2010). Low-grade endotoxemia in patients with severe autism. Neuroscience Letters, 471, 162–165.Google Scholar
Favre, M. R., Barkat, T. R., Lamendola, D., et al. (2013). General developmental health in the VPA-rat model of autism. Frontiers in Behavioral Neuroscience, 7, 88.Google Scholar
Feil, R., & Fraga, M. F. (2012). Epigenetics and the environment: Emerging patterns and implications. Nature Reviews Genetics, 13, 97–109.Google Scholar
Finegold, S. M., Molitoris, D., Song, Y., et al. (2002). Gastrointestinal microflora studies in late-onset autism. Clinical Infectious Diseases, 35, S6–S16.Google Scholar
Foley, K. A., Ossenkopp, K. P., Kavaliers, M., & Macfabe, D. F. (2014). Pre- and neonatal exposure to lipopolysaccharide or the enteric metabolite, propionic acid, alters development and behavior in adolescent rats in a sexually dimorphic manner. PLoS ONE, 9, e87072.Google Scholar
Fullwood, M. J., & Ruan, Y. (2009). ChIP-based methods for the identification of long-range chromatin interactions. Journal of Cellular Biochemistry, 107, 30–39.Google Scholar
Fullwood, M. J., Liu, M. H., Pan, Y. F., et al. (2009). An oestrogen-receptor-alpha-bound human chromatin interactome. Nature, 462, 58–64.Google Scholar
Galloway, T., & Handy, R. (2003). Immunotoxicity of organophosphorous pesticides. Ecotoxicology, 12, 345–363.Google Scholar
Gardener, H., Spiegelman, D., & Buka, S. L. (2009). Prenatal risk factors for autism: Comprehensive meta-analysis. British Journal of Psychiatry, 195, 7–14.Google Scholar
Gardener, H., Spiegelman, D., & Buka, S. L. (2011). Perinatal and neonatal risk factors for autism: A comprehensive meta-analysis. Pediatrics, 128, 344–355.Google Scholar
Garry, V. F., Harkins, M. E., Erickson, L. L., et al. (2002). Birth defects, season of conception, and sex of children born to pesticide applicators living in the Red River Valley of Minnesota, USA. Environmental Health Perspectives, 110(Suppl. 3), 441–449.Google Scholar
Gentile, S. (2014). Risks of neurobehavioral teratogenicity associated with prenatal exposure to valproate monotherapy: A systematic review with regulatory repercussions. CNS Spectrums, 19, 305–315.Google Scholar
Gerhart, J., & Kirschner, M. (1997). Cells, Embryos, and Evolution: Toward a Cellular and Developmental Understanding of Phenotypic Variation and Evolutionary Adaptability, Malden, MA: Blackwell Science.Google Scholar
Griesi-Oliveira, K., Acab, A., Gupta, A. R., et al. (2015). Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. Molecular Psychiatry, 20, 1350–1365.Google Scholar
Gu, H., Smith, Z. D., Bock, C., et al. (2011). Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling. Nature Protocols, 6, 468–481.Google Scholar
Guevara-Guzman, R., Arriaga, V., Kendrick, K. M., et al. (2009). Estradiol prevents ozone-induced increases in brain lipid peroxidation and impaired social recognition memory in female rats. Neuroscience, 159, 940–950.Google Scholar
Guo, H., Zhu, P., Guo, F., et al. (2015). Profiling DNA methylome landscapes of mammalian cells with single-cell reduced-representation bisulfite sequencing. Nature Protocols, 10, 645–659.Google Scholar
Gurer, H., & Ercal, N. (2000). Can antioxidants be beneficial in the treatment of lead poisoning? Free Radical Biology and Medicine, 29, 927–945.Google Scholar
Guzzi, G., & La Porta, C. A. (2008). Molecular mechanisms triggered by mercury. Toxicology, 244, 1–12.Google Scholar
Handy, D. E., Castro, R., & Loscalzo, J. (2011). Epigenetic modifications: Basic mechanisms and role in cardiovascular disease. Circulation, 123, 2145–2156.Google Scholar
Hannon, E., Lunnon, K., Schalkwyk, L., & Mill, J. (2015). Interindividual methylomic variation across blood, cortex, and cerebellum: Implications for epigenetic studies of neurological and neuropsychiatric phenotypes. Epigenetics, 10, 1024–1032.Google Scholar
Hayashi, K. (1975). Distribution of histone F1 on calf thymus nucleohistone DNA. Journal of Molecular Biology, 94, 397–408.CrossRefGoogle ScholarPubMed
He, Y., & Ecker, J. R. (2015). Non-CG methylation in the human genome. Annual Review of Genomics Human Genetics, 16, 55–77.Google Scholar
Henikoff, S., & Shilatifard, A. (2011). Histone modification: Cause or cog? Trends in Genetics, 27, 389–396.Google Scholar
Hermanowicz, A., & Kossman, S. (1984). Neutrophil function and infectious disease in workers occupationally exposed to phosphoorganic pesticides: Role of mononuclear-derived chemotactic factor for neutrophils. Clinical Immunology and Immunopathology, 33, 13–22.Google Scholar
Hoffman, D. J., Heinz, G. H., Sileo, L., et al. (2000). Developmental toxicity of lead-contaminated sediment in Canada geese (Branta canadensis). Journal of Toxicology and Environmental Health A, 59, 235–252.Google ScholarPubMed
Hormanseder, E., Simeone, A., Allen, G. E., et al. (2017). H3K4 methylation-dependent memory of somatic cell identity inhibits reprogramming and development of nuclear transfer embryos. Cell Stem Cell, 21, 135–143.e6.Google Scholar
Hsiao, E. Y., McBride, S. W., Hsien, S., et al. (2013). Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders. Cell, 155, 1451–1463.Google Scholar
Hsieh, T. S., Fudenberg, G., Goloborodko, A., & Rando, O. J. (2016). Micro-C XL: Assaying chromosome conformation from the nucleosome to the entire genome. Nature Methods, 13, 1009–1011.Google Scholar
Hunaiti, A. A., & Soud, M. (2000). Effect of lead concentration on the level of glutathione, glutathione S-transferase, reductase and peroxidase in human blood. Science of the Total Environment, 248, 45–50.Google Scholar
Hurwitz, J. (2005). The discovery of RNA polymerase. Journal of Biological Chemistry, 280, 42477–42485.Google Scholar
Ji, W., Yang, L., Yu, L., et al. (2008). Epigenetic silencing of O6-methylguanine DNA methyltransferase gene in NiS-transformed cells. Carcinogenesis, 29, 1267–1275.Google Scholar
Ji, H., Biagini Myers, J. M., Brandt, E. B., et al. (2016). Air pollution, epigenetics, and asthma. Allergy, Asthma & Clinical Immunology, 12, 51.Google Scholar
Johnson, D. S., Mortazavi, A., Myers, R. M., & Wold, B. (2007). Genome-wide mapping of in vivo protein–DNA interactions. Science, 316, 1497–1502.Google Scholar
Jomova, K., & Valko, M. (2011). Advances in metal-induced oxidative stress and human disease. Toxicology, 283, 65–87.Google Scholar
Jyonouchi, H., Sun, S., & Le, H. (2001). Proinflammatory and regulatory cytokine production associated with innate and adaptive immune responses in children with autism spectrum disorders and developmental regression. Journal of Neuroimmunology, 120, 170–179.Google Scholar
Kalkbrenner, A. E., Daniels, J. L., Chen, J. C., et al. (2010). Perinatal exposure to hazardous air pollutants and autism spectrum disorders at age 8. Epidemiology, 21, 631–641.Google Scholar
Kang, D. W., Park, J. G., Ilhan, Z. E., et al. (2013). Reduced incidence of Prevotella and other fermenters in intestinal microflora of autistic children. PLoS ONE, 8, e68322.Google Scholar
Kanwal, R., Gupta, K., & Gupta, S. (2015). Cancer epigenetics: An introduction. Methods in Molecular Biology, 1238, 3–25.Google Scholar
Karaczyn, A. A., Golebiowski, F., & Kasprzak, K. S. (2006). Ni(II) affects ubiquitination of core histones H2B and H2A. Experimental Cell Research, 312, 3252–3259.Google Scholar
Ke, Q., Ellen, T. P., & Costa, M. (2008). Nickel compounds induce histone ubiquitination by inhibiting histone deubiquitinating enzyme activity. Toxicology and Applied Pharmacology, 228, 190–199.Google Scholar
Kim, K. C., Choi, C. S., Kim, J. W., et al. (2016). MeCP2 modulates sex differences in the postsynaptic development of the valproate animal model of autism. Molecular Neurobiology, 53, 40–56.Google Scholar
Kim, K. Y., Hysolli, E., & Park, I. H. (2011). Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome. Proceedings of the National Academy of Sciences, 108, 14169–14174.Google Scholar
Kinney, D. K., Munir, K. M., Crowley, D. J., & Miller, A. M. (2008). Prenatal stress and risk for autism. Neuroscience & Biobehavioral Reviews, 32, 1519–1532.Google Scholar
Kobayashi, T., Matsuyama, T., Takeuchi, M., & Ito, S. (2016). Autism spectrum disorder and prenatal exposure to selective serotonin reuptake inhibitors: A systematic review and meta-analysis. Reproductive Toxicology, 65, 170–178.Google Scholar
Kosidou, K., Dalman, C., Widman, L., et al. (2016). Maternal polycystic ovary syndrome and the risk of autism spectrum disorders in the offspring: A population-based nationwide study in Sweden. Molecular Psychiatry, 21, 1441–1448.Google Scholar
Kratsman, N., Getselter, D., & Elliott, E. (2016). Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model. Neuropharmacology, 102, 136–145.Google Scholar
Krey, J. F., Pasca, S. P., Shcheglovitov, A., et al. (2013). Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons. Nature Neuroscience, 16, 201–209.Google Scholar
Kuo, H. Y., & Liu, F. C. (2017). Valproic acid induces aberrant development of striatal compartments and corticostriatal pathways in a mouse model of autism spectrum disorder. FASEB Journal, 31, 4458–4472.Google Scholar
Kuo, M. H., & Allis, C. D. (1999). In vivo cross-linking and immunoprecipitation for studying dynamic protein:DNA associations in a chromatin environment. Methods, 19, 425–433.Google Scholar
Lancaster, M. A., Renner, M., Martin, C. A., et al. (2013). Cerebral organoids model human brain development and microcephaly. Nature, 501, 373–379.Google Scholar
Lancaster, M. A., Corsini, N. S., Wolfinger, S., et al. (2017). Guided self-organization and cortical plate formation in human brain organoids. Nature Biotechnology, 35, 659–666.Google Scholar
Latchman, D. S. (1997). Transcription factors: An overview. International Journal of Biochemistry & Cell Biology, 29, 1305–1312.Google Scholar
Law, J. A., & Jacobsen, S. E. (2010). Establishing, maintaining and modifying DNA methylation patterns in plants and animals. Nature Reviews Genetics, 11, 204–220.Google Scholar
Li, Q. (2007). New mechanism of organophosphorus pesticide-induced immunotoxicity. Journal of Nippon Medical School, 74, 70–73.Google Scholar
Li, Q., Han, Y., Dy, A. B. C., & Hagerman, R. J. (2017). The gut microbiota and autism spectrum disorders. Frontiers in Cellular Neuroscience, 11, 120.Google Scholar
Liang, J., Zhu, H., Li, C., et al. (2012). Neonatal exposure to benzo[a]pyrene decreases the levels of serum testosterone and histone H3K14 acetylation of the StAR promoter in the testes of SD rats. Toxicology, 302, 285–291.Google Scholar
Lieberman-Aiden, E., van Berkum, N. L., Williams, L., et al. (2009). Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science, 326, 289–293.Google Scholar
Lin, V. W., Baccarelli, A. A., & Burris, H. H. (2016). Epigenetics – A potential mediator between air pollution and preterm birth. Environmental Epigenetics, 2, dvv008.Google Scholar
Ling, Z., Zhu, Y., Tong, C., et al. (2006). Progressive dopamine neuron loss following supra-nigral lipopolysaccharide (LPS) infusion into rats exposed to LPS prenatally. Experimental Neurology, 199, 499–512.Google Scholar
Lister, R., Mukamel, E. A., Nery, J. R., et al. (2013). Global epigenomic reconfiguration during mammalian brain development. Science, 341, 1237905.Google Scholar
Long, T. C., Tajuba, J., Sama, P., et al. (2007). Nanosize titanium dioxide stimulates reactive oxygen species in brain microglia and damages neurons in vitro. Environmental Health Perspectives, 115, 1631–1637.Google Scholar
M’Bemba-Meka, P., Lemieux, N., & Chakrabarti, S. K. (2007). Role of oxidative stress and intracellular calcium in nickel carbonate hydroxide-induced sister-chromatid exchange, and alterations in replication index and mitotic index in cultured human peripheral blood lymphocytes. Archives of Toxicology, 81, 89–99.Google Scholar
Madisen, L., Krumm, A., Hebbes, T. R., & Groudine, M. (1998). The immunoglobulin heavy chain locus control region increases histone acetylation along linked c-myc genes. Molecular and Cellular Biology, 18, 6281–6292.Google Scholar
Madrigano, J., Baccarelli, A., Mittleman, M. A., et al. (2012). Air pollution and DNA methylation: Interaction by psychological factors in the VA Normative Aging Study. American Journal of Epidemiology, 176, 224–232.Google Scholar
Manousakis, G., Jensen, M. B., Chacon, M. R., Sattin, J. A., & Levine, R. L. (2009). The interface between stroke and infectious disease: Infectious diseases leading to stroke and infections complicating stroke. Current Neurology and Neuroscience Reports, 9, 28–34.Google Scholar
Mao, Z., Bonni, A., Xia, F., Nadal-Vicens, M., & Greenberg, M. E. (1999). Neuronal activity-dependent cell survival mediated by transcription factor MEF2. Science, 286, 785–790.Google Scholar
Marchetto, M. C., Carromeu, C., Acab, A., et al. (2010). A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell, 143, 527–539.Google Scholar
Marchetto, M. C., Belinson, H., Tian, Y., et al. (2017). Altered proliferation and networks in neural cells derived from idiopathic autistic individuals. Molecular Psychiatry, 22, 820–835.Google Scholar
Mariani, J., Coppola, G., Zhang, P., et al. (2015). FOXG1-dependent dysregulation of GABA/glutamate neuron differentiation in autism spectrum disorders. Cell, 162, 375–390.Google Scholar
Martinez-Zamudio, R., & Ha, H. C. (2011). Environmental epigenetics in metal exposure. Epigenetics, 6, 820–827.Google Scholar
Mascetti, V. L., & Pedersen, R. A. (2016). Human–mouse chimerism validates human stem cell pluripotency. Cell Stem Cell, 18, 67–72.Google Scholar
Masi, A., Quintana, D. S., Glozier, N., et al. (2015). Cytokine aberrations in autism spectrum disorder: A systematic review and meta-analysis. Molecular Psychiatry, 20, 440–446.Google Scholar
McCanlies, E. C., Fekedulegn, D., Mnatsakanova, A., et al. (2012). Parental occupational exposures and autism spectrum disorder. Journal of Autism and Developmental Disorders, 42, 2323–2334.Google Scholar
McCarthy, M. M., & Nugent, B. M. (2013). Epigenetic contributions to hormonally-mediated sexual differentiation of the brain. Journal of Neuroendocrinology, 25, 1133–1140.Google Scholar
McConnachie, P. R., & Zahalsky, A. C. (1992). Immune alterations in humans exposed to the termiticide technical chlordane. Archives of Environmental Health, 47, 295–301.Google Scholar
McCormick, H., Young, P. E., Hur, S. S. J., et al. (2017). Isogenic mice exhibit sexually-dimorphic DNA methylation patterns across multiple tissues. BMC Genomics, 18, 966.Google Scholar
McLachlan, J. A., Simpson, E., & Martin, M. (2006). Endocrine disrupters and female reproductive health. Best Practice & Research: Clinical Endocrinology & Metabolism, 20, 63–75.Google Scholar
Mills, N. L., Donaldson, K., Hadoke, P. W., et al. (2009). Adverse cardiovascular effects of air pollution. Nature Clinical Practice Cardiovascular Medicine, 6, 36–44.Google Scholar
Mittal, V. A., Ellman, L. M., & Cannon, T. D. (2008). Gene–environment interaction and covariation in schizophrenia: The role of obstetric complications. Schizophrenia Bulletin, 34, 1083–1094.Google Scholar
Modabbernia, A., Mollon, J., Boffetta, P., & Reichenberg, A. (2016). Impaired gas exchange at birth and risk of intellectual disability and autism: A meta-analysis. Journal of Autism and Developmental Disorders, 46, 1847–1859.Google Scholar
Modabbernia, A., Velthorst, E., & Reichenberg, A. (2017). Environmental risk factors for autism: An evidence-based review of systematic reviews and meta-analyses. Molecular Autism, 8, 13.Google Scholar
Mohle, L., Mattei, D., Heimesaat, M. M., et al. (2016). Ly6 C(Hi) monocytes provide a link between antibiotic-induced changes in gut microbiota and adult hippocampal neurogenesis. Cell Reports, 15, 1945–1956.Google Scholar
Muotri, A. R., Marchetto, M. C., Coufal, N. G., et al. (2010). L1 retrotransposition in neurons is modulated by MeCP2. Nature, 468, 443–446.Google Scholar
Nagano, T., Lubling, Y., Stevens, T. J., et al. (2013). Single-cell Hi-C reveals cell-to-cell variability in chromosome structure. Nature, 502, 59–64.Google Scholar
Nardone, S., Sams, D. S., Zito, A., Reuveni, E., & Elliott, E. (2017). Dysregulation of cortical neuron DNA methylation profile in autism spectrum disorder. Cerebral Cortex, 27, 5739–5754.Google Scholar
Naumova, O. Y., Dozier, M., Dobrynin, P. V., et al. (2018). Developmental dynamics of the epigenome: A longitudinal study of three toddlers. Neurotoxicology and Teratology, 66, 125–131.Google Scholar
Nemmar, A., & Inuwa, I. M. (2008). Diesel exhaust particles in blood trigger systemic and pulmonary morphological alterations. Toxicology Letters, 176, 20–30.Google Scholar
Nwankwo, D. O., & Wilson, G. G. (1988). Cloning and expression of the MspI restriction and modification genes. Gene, 64, 1–8.Google Scholar
O’Neill, L. A., & Kaltschmidt, C. (1997). NF-kappa B: A crucial transcription factor for glial and neuronal cell function. Trends in Neurosciences, 20, 252–258.Google Scholar
O’Roak, B. J., Deriziotis, P., Lee, C., et al. (2011). Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations. Nature Genetics, 43, 585–589.Google Scholar
O’Roak, B. J., Vives, L., Girirajan, S., et al. (2012). Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations. Nature, 485, 246–250.Google Scholar
Oberdorster, G., Sharp, Z., Atudorei, V., et al. (2004). Translocation of inhaled ultrafine particles to the brain. Inhalation Toxicology, 16, 437–445.Google Scholar
Onishchenko, N., Karpova, N., Sabri, F., Castren, E., & Ceccatelli, S. (2008). Long-lasting depression-like behavior and epigenetic changes of BDNF gene expression induced by perinatal exposure to methylmercury. Journal of Neurochemistry, 106, 1378–1387.Google Scholar
Palmer, R. F., Blanchard, S., Stein, Z., Mandell, D., & Miller, C. (2006). Environmental mercury release, special education rates, and autism disorder: An ecological study of Texas. Health & Place, 12, 203–209.Google Scholar
Palmer, R. F., Blanchard, S., & Wood, R. (2009). Proximity to point sources of environmental mercury release as a predictor of autism prevalence. Health & Place, 15, 18–24.Google Scholar
Papp, B., & Plath, K. (2013). Epigenetics of reprogramming to induced pluripotency. Cell, 152, 1324–1343.Google Scholar
Parikshak, N. N., Luo, R., Zhang, A., et al. (2013). Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism. Cell, 155, 1008–1021.Google Scholar
Parikshak, N. N., Swarup, V., Belgard, T. G., et al. (2016). Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism. Nature, 540, 423–427.Google Scholar
Parracho, H. M., Bingham, M. O., Gibson, G. R., & McCartney, A. L. (2005). Differences between the gut microflora of children with autistic spectrum disorders and that of healthy children. Journal of Medical Microbiology, 54, 987–991.Google Scholar
Pasca, A. M., Sloan, S. A., Clarke, L. E., et al. (2015). Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture. Nature Methods, 12, 671–678.Google Scholar
Pasca, S. P., Portmann, T., Voineagu, I., et al. (2011). Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome. Nature Medicine, 17, 1657–1662.Google Scholar
Patrick, L. (2006). Lead toxicity part II: The role of free radical damage and the use of antioxidants in the pathology and treatment of lead toxicity. Alternative Medicine Review, 11, 114–127.Google Scholar
Pavanello, S., Pesatori, A. C., Dioni, L., et al. (2010). Shorter telomere length in peripheral blood lymphocytes of workers exposed to polycyclic aromatic hydrocarbons. Carcinogenesis, 31, 216–221.Google Scholar
Pereyra-Munoz, N., Rugerio-Vargas, C., Angoa-Perez, M., Borgonio-Perez, G., & Rivas-Arancibia, S. (2006). Oxidative damage in substantia nigra and striatum of rats chronically exposed to ozone. Journal of Chemical Neuroanatomy, 31, 114–123.Google Scholar
Perry, V. H., Cunningham, C., & Holmes, C. (2007). Systemic infections and inflammation affect chronic neurodegeneration. Nature Reviews Immunology, 7, 161–167.Google Scholar
Persico, A. M., & Napolioni, V. (2013). Urinary p-cresol in autism spectrum disorder. Neurotoxicology and Teratology, 36, 82–90.Google Scholar
Phillips, T. M. (2000). Assessing environmental exposure in children: Immunotoxicology screening. Journal of Exposure Analysis and Environmental Epidemiology, 10, 769–775.Google Scholar
Pohl, A., Cassidy, S., Auyeung, B., & Baron-Cohen, S. (2014). Uncovering steroidopathy in women with autism: A latent class analysis. Molecular Autism, 5, 27.Google Scholar
Price, C. S., Thompson, W. W., Goodson, B., et al. (2010). Prenatal and infant exposure to thimerosal from vaccines and immunoglobulins and risk of autism. Pediatrics, 126, 656–664.Google Scholar
Price, D. J., & Joshi, J. G. (1983). Ferritin. Binding of beryllium and other divalent metal ions. Journal of Biological Chemistry, 258, 10873–10880.Google Scholar
Qin, L., Wu, X., Block, M. L., et al. (2007). Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration. Glia, 55, 453–462.Google Scholar
Quadrato, G., Nguyen, T., Macosko, E. Z., et al. (2017). Cell diversity and network dynamics in photosensitive human brain organoids. Nature, 545, 48–53.Google Scholar
Quigley, E. M. (2016). Leaky gut – Concept or clinical entity? Current Opinion in Gastroenterology, 32, 74–79.Google Scholar
Ramani, V., Deng, X., Qiu, R., et al. (2017). Massively multiplex single-cell Hi-C. Nature Methods, 14, 263–266.Google Scholar
Rammes, G., Steckler, T., Kresse, A., et al. (2000). Synaptic plasticity in the basolateral amygdala in transgenic mice expressing dominant-negative cAMP response element-binding protein (CREB) in forebrain. European Journal of Neuroscience, 12, 2534–2546.Google Scholar
Rauh, V. A., Garfinkel, R., Perera, F. P., et al. (2006). Impact of prenatal chlorpyrifos exposure on neurodevelopment in the first 3 years of life among inner-city children. Pediatrics, 118, e1845–e1859.Google Scholar
Ray, D. E., & Richards, P. G. (2001). The potential for toxic effects of chronic, low-dose exposure to organophosphates. Toxicology Letters, 120, 343–351.Google Scholar
Reed, A., Dzon, L., Loganathan, B. G., & Whalen, M. M. (2004). Immunomodulation of human natural killer cell cytotoxic function by organochlorine pesticides. Human & Experimental Toxicology, 23, 463–471.Google Scholar
Repetto, R., & Baliga, S. S. (1997). Pesticides and immunosuppression: The risks to public health. Health Policy and Planning, 12, 97–106.Google Scholar
Rieder, R., Wisniewski, P. J., Alderman, B. L., & Campbell, S. C. (2017). Microbes and mental health: A review. Brain, Behavior, and Immunity, 66, 9–17.Google Scholar
Rivest, S., Lacroix, S., Vallieres, L., et al. (2000). How the blood talks to the brain parenchyma and the paraventricular nucleus of the hypothalamus during systemic inflammatory and infectious stimuli. Proceedings of the Society for Experimental Biology and Medicine, 223, 22–38.Google Scholar
Roberts, A. L., Lyall, K., Hart, J. E., et al. (2013). Perinatal air pollutant exposures and autism spectrum disorder in the children of Nurses’ Health Study II participants. Environmental Health Perspectives, 121, 978–984.Google Scholar
Roberts, E. M., & English, P. B. (2013). Bayesian modeling of time-dependent vulnerability to environmental hazards: An example using autism and pesticide data. Statistics in Medicine, 32, 2308–2319.Google Scholar
Roberts, E. M., English, P. B., Grether, J. K., et al. (2007). Maternal residence near agricultural pesticide applications and autism spectrum disorders among children in the California Central Valley. Environmental Health Perspectives, 115, 1482–1489.Google Scholar
Ronald, A., Pennell, C. E., & Whitehouse, A. J. (2010). Prenatal maternal stress associated with ADHD and autistic traits in early childhood. Frontiers in Psychology, 1, 223.Google Scholar
Rossignol, D. A., Genuis, S. J., & Frye, R. E. (2014). Environmental toxicants and autism spectrum disorders: A systematic review. Translational Psychiatry, 4, e360.Google Scholar
Rossnerova, A., Tulupova, E., Tabashidze, N., et al. (2013). Factors affecting the 27 K DNA methylation pattern in asthmatic and healthy children from locations with various environments. Mutation Research, 741 –742, 18–26.Google Scholar
Rouhani, F., Kumasaka, N., de Brito, M. C., et al. (2014). Genetic background drives transcriptional variation in human induced pluripotent stem cells. PLoS Genetics, 10, e1004432.Google Scholar
Sanders, S. J., He, X., Willsey, A. J., et al. (2015). Insights into autism spectrum disorder genomic architecture and biology from 71 risk loci. Neuron, 87, 1215–1233.Google Scholar
Sassone-Corsi, P., & Christen, Y. (2015). A Time for Metabolism and Hormones. New York: Springer Berlin Heidelberg.Google Scholar
Schaalan, M. F., Abdelraouf, S. M., Mohamed, W. A., & Hassanein, F. S. (2012). Correlation between maternal milk and infant serum levels of chlorinated pesticides (CP) and the impact of elevated CP on bleeding tendency and immune status in some infants in Egypt. Journal of Immunotoxicology, 9, 15–24.Google Scholar
Sen, A., Sherr, C. J., & Todaro, G. J. (1976). Specific binding of the type C viral core protein p12 with purified viral RNA. Cell, 7, 21–32.Google Scholar
Sharon, G., Sampson, T. R., Geschwind, D. H., & Mazmanian, S. K. (2016). The central nervous system and the gut microbiome. Cell, 167, 915–932.Google Scholar
Sheldon, A. L., & Robinson, M. B. (2007). The role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention. Neurochemistry International, 51, 333–355.Google Scholar
Sheridan, S. D., Theriault, K. M., Reis, S. A., et al. (2011). Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome. PLoS ONE, 6, e26203.Google Scholar
Shi, L., Fatemi, S. H., Sidwell, R. W., & Patterson, P. H. (2003). Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring. Journal of Neuroscience, 23, 297–302.Google Scholar
Shi, Y., Kirwan, P., & Livesey, F. J. (2012). Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks. Nature Protocols, 7, 1836–1846.Google Scholar
Shutoh, Y., Takeda, M., Ohtsuka, R., et al. (2009). Low dose effects of dichlorodiphenyltrichloroethane (DDT) on gene transcription and DNA methylation in the hypothalamus of young male rats: Implication of hormesis-like effects. Journal of Toxicological Sciences, 34, 469–482.Google Scholar
Silveyra, P., & Floros, J. (2012). Air pollution and epigenetics: Effects on SP-A and innate host defence in the lung. Swiss Medical Weekly, 142, w13579.Google Scholar
Sofer, T., Baccarelli, A., Cantone, L., et al. (2013). Exposure to airborne particulate matter is associated with methylation pattern in the asthma pathway. Epigenomics, 5, 147–154.Google Scholar
Somji, S., Garrett, S. H., Toni, C., et al. (2011). Differences in the epigenetic regulation of MT-3 gene expression between parental and Cd+2 or As+3 transformed human urothelial cells. Cancer Cell International, 11, 2.Google Scholar
Song, C., Kanthasamy, A., Anantharam, V., Sun, F., & Kanthasamy, A. G. (2010). Environmental neurotoxic pesticide increases histone acetylation to promote apoptosis in dopaminergic neuronal cells: Relevance to epigenetic mechanisms of neurodegeneration. Molecular Pharmacology, 77, 621–632.Google Scholar
Song, C., Kanthasamy, A., Jin, H., Anantharam, V., & Kanthasamy, A. G. (2011). Paraquat induces epigenetic changes by promoting histone acetylation in cell culture models of dopaminergic degeneration. Neurotoxicology, 32, 586–595.Google Scholar
Song, Y., Liu, C., & Finegold, S. M. (2004). Real-time PCR quantitation of clostridia in feces of autistic children. Applied and Environmental Microbiology, 70, 6459–6465.Google Scholar
Stouder, C., & Paoloni-Giacobino, A. (2011). Specific transgenerational imprinting effects of the endocrine disruptor methoxychlor on male gametes. Reproduction, 141, 207–216.Google Scholar
Stroud, H., Su, S. C., Hrvatin, S., et al. (2017). Early-life gene expression in neurons modulates lasting epigenetic states. Cell, 171, 1151–1164.e16.Google Scholar
Sun, W., Poschmann, J., Cruz-Herrera Del Rosario, R., et al. (2016). Histone acetylome-wide association study of autism spectrum disorder. Cell, 167, 1385–1397.e11.Google Scholar
Suzuki, K., Matsuzaki, H., Iwata, K., et al. (2011). Plasma cytokine profiles in subjects with high-functioning autism spectrum disorders. PLoS ONE, 6, e20470.Google Scholar
Takahashi, K., & Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell, 126, 663–676.Google Scholar
Takahashi, K., Tanabe, K., Ohnuki, M., et al. (2007). Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell, 131, 861–872.Google Scholar
Takiguchi, M., Achanzar, W. E., Qu, W., Li, G., & Waalkes, M. P. (2003). Effects of cadmium on DNA-(cytosine-5) methyltransferase activity and DNA methylation status during cadmium-induced cellular transformation. Experimental Cell Research, 286, 355–365.Google Scholar
Tang, S. C., Sheu, G. T., Wong, R. H., et al. (2010). Expression of glutathione S-transferase M2 in stage I/II non-small cell lung cancer and alleviation of DNA damage exposure to benzo[a]pyrene. Toxicology Letters, 192, 316–323.Google Scholar
Thomson, E. M., Kumarathasan, P., Calderon-Garciduenas, L., & Vincent, R. (2007). Air pollution alters brain and pituitary endothelin-1 and inducible nitric oxide synthase gene expression. Environmental Research, 105, 224–233.Google Scholar
Tin Tin Win, S., Mitsushima, D., Yamamoto, S., et al. (2008). Changes in neurotransmitter levels and proinflammatory cytokine mRNA expressions in the mice olfactory bulb following nanoparticle exposure. Toxicology and Applied Pharmacology, 226, 192–198.Google Scholar
Tomova, A., Husarova, V., Lakatosova, S., et al. (2015). Gastrointestinal microbiota in children with autism in Slovakia. Physiology & Behavior, 138, 179–187.Google Scholar
Tsai, H. W., Grant, P. A., & Rissman, E. F. (2009). Sex differences in histone modifications in the neonatal mouse brain. Epigenetics, 4, 47–53.Google Scholar
Ulahannan, N., & Greally, J. M. (2015). Genome-wide assays that identify and quantify modified cytosines in human disease studies. Epigenetics & Chromatin, 8, 5.Google Scholar
Urich, M. A., Nery, J. R., Lister, R., Schmitz, R. J., & Ecker, J. R. (2015). MethylC-seq library preparation for base-resolution whole-genome bisulfite sequencing. Nature Protocols, 10, 475–483.Google Scholar
Valavanidis, A., Fiotakis, K., & Vlachogianni, T. (2008). Airborne particulate matter and human health: Toxicological assessment and importance of size and composition of particles for oxidative damage and carcinogenic mechanisms. Journal of Environmental Science Health, Part C: Environmental Carcinogenesis & Ecotoxicology Reviews, 26, 339–362.Google Scholar
Vardabasso, C., Hasson, D., Ratnakumar, K., et al. (2014). Histone variants: Emerging players in cancer biology. Cellular and Molecular Life Sciences, 71, 379–404.Google Scholar
Vine, M. F., Stein, L., Weigle, K., et al. (2000). Effects on the immune system associated with living near a pesticide dump site. Environmental Health Perspectives, 108, 1113–1124.Google Scholar
Voineagu, I., Wang, X., Johnston, P., et al. (2011). Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature, 474, 380–384.Google Scholar
Volk, H. E., Hertz-Picciotto, I., Delwiche, L., Lurmann, F., & McConnell, R. (2011). Residential proximity to freeways and autism in the CHARGE study. Environmental Health Perspectives, 119, 873–877.Google Scholar
Volk, H. E., Lurmann, F., Penfold, B., Hertz-Picciotto, I., & McConnell, R. (2013). Traffic-related air pollution, particulate matter, and autism. JAMA Psychiatry, 70, 71–77.Google Scholar
Vuong, H. E., & Hsiao, E. Y. (2017). Emerging roles for the gut microbiome in autism spectrum disorder. Biological Psychiatry, 81, 411–423.Google Scholar
Waalkes, M. P. (2000). Cadmium carcinogenesis in review. Journal of Inorganic Biochemistry, 79, 241–244.Google Scholar
Wang, B., Feng, W. Y., Wang, M., et al. (2007). Transport of intranasally instilled fine Fe2O3 particles into the brain: Micro-distribution, chemical states, and histopathological observation. Biological Trace Element Research, 118, 233–243.Google Scholar
Wang, J., Liu, Y., Jiao, F., et al. (2008). Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO2 nanoparticles. Toxicology, 254, 82–90.Google Scholar
Wang, L., Christophersen, C. T., Sorich, M. J., et al. (2012). Elevated fecal short chain fatty acid and ammonia concentrations in children with autism spectrum disorder. Digestive Diseases and Sciences, 57, 2096–2102.Google Scholar
Wang, L., Christophersen, C. T., Sorich, M. J., et al. (2013). Increased abundance of Sutterella spp. and Ruminococcus torques in feces of children with autism spectrum disorder. Molecular Autism, 4, 42.Google Scholar
Warren, N., Caric, D., Pratt, T., et al. (1999). The transcription factor, Pax6, is required for cell proliferation and differentiation in the developing cerebral cortex. Cerebral Cortex, 9, 627–635.Google Scholar
Watjen, W., & Beyersmann, D. (2004). Cadmium-induced apoptosis in C6 glioma cells: Influence of oxidative stress. Biometals, 17, 65–78.Google Scholar
Wigle, D. T., Arbuckle, T. E., Turner, M. C., et al. (2008). Epidemiologic evidence of relationships between reproductive and child health outcomes and environmental chemical contaminants. Journal of Toxicology and Environmental Health, Part B: Critical Reviews, 11, 373–517.Google Scholar
Williams, B. L., Hornig, M., Buie, T., et al. (2011). Impaired carbohydrate digestion and transport and mucosal dysbiosis in the intestines of children with autism and gastrointestinal disturbances. PLoS ONE, 6, e24585.Google Scholar
Windham, G. C., Zhang, L., Gunier, R., Croen, L. A., & Grether, J. K. (2006). Autism spectrum disorders in relation to distribution of hazardous air pollutants in the San Francisco Bay Area. Environmental Health Perspectives, 114, 1438–1444.Google Scholar
Wright, R. O., Schwartz, J., Wright, R. J., et al. (2010). Biomarkers of lead exposure and DNA methylation within retrotransposons. Environmental Health Perspectives, 118, 790–795.Google Scholar
Wu, S., Wu, F., Ding, Y., et al. (2017). Advanced parental age and autism risk in children: A systematic review and meta-analysis. Acta Psychiatrica Scandinavica, 135, 29–41.Google Scholar
Xu, N., Li, X., & Zhong, Y. (2015). Inflammatory cytokines: Potential biomarkers of immunologic dysfunction in autism spectrum disorders. Mediators of Inflammation, 2015, 531518.Google Scholar
Xu, Q. S., Roberts, R. J., & Guo, H. C. (2005). Two crystal forms of the restriction enzyme MspI-DNA complex show the same novel structure. Protein Science, 14, 2590–2600.Google Scholar
Yan, Y., Kluz, T., Zhang, P., Chen, H. B., & Costa, M. (2003). Analysis of specific lysine histone H3 and H4 acetylation and methylation status in clones of cells with a gene silenced by nickel exposure. Toxicology and Applied Pharmacology, 190, 272–277.Google Scholar
Ye, F., & Xu, X. C. (2010). Benzo[a]pyrene diol epoxide suppresses retinoic acid receptor-beta2 expression by recruiting DNA (cytosine-5-)-methyltransferase 3A. Molecular Cancer, 9, 93.Google Scholar
Yoshimasu, K., Kiyohara, C., Takemura, S., & Nakai, K. (2014). A meta-analysis of the evidence on the impact of prenatal and early infancy exposures to mercury on autism and attention deficit/hyperactivity disorder in the childhood. Neurotoxicology, 44, 121–131.Google Scholar
Zama, A. M., & Uzumcu, M. (2009). Fetal and neonatal exposure to the endocrine disruptor methoxychlor causes epigenetic alterations in adult ovarian genes. Endocrinology, 150, 4681–4691.Google Scholar