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Chapter 9 - Blood and Transfusion

Published online by Cambridge University Press:  30 November 2019

By
Megha K. Kanjia
Edited by
Adam C. Adler ,
Arvind Chandrakantan  and
Ronald S. Litman
Adam C. Adler
Affiliation:
Texas Children's Hospital
Arvind Chandrakantan
Affiliation:
Texas Children's Hospital
Ronald S. Litman
Affiliation:
The Children's Hospital of Philadelphia
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Summary

In this chapter on hematology and transfusion, the author reviews commonly encountered perioperative disorders such as hemoglobinopathies, G6PD, Sickle Cell Disease, von Willebrand Disease and Hemophilia. Pediatric transfusion of blood components is discussed as well as use of thromboelastography to guide treatment.

Keywords

HemoglobinopathiesG6PDSickle Cell Diseasefetal hemoglobinThalassemiavon Willebrand DiseaseHemophiliaTransfusioncryoprecipitateplasmaplateletsMassive Blood TransfusionthromboelastographyTRALIAntifibrinolyticsAminocaproic acidTranexamic acid.
Type
Chapter
Information
Case Studies in Pediatric Anesthesia , pp. 38 - 45
Publisher: Cambridge University Press
Print publication year: 2019

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References

Suggested Reading

Haas, T, Goobie, S, Spielmann, N, et al. Improvements in patient blood management for pediatric craniosynostosis surgery using a ROTEM(®)-assisted strategy – feasibility and costs. Paediatr Anaesth. 2014;24(7):774–80, PMID: 24417649.CrossRefGoogle ScholarPubMed
Haas, T, Spielmann, N, Mauch, J, et al. Comparison of thromboelastometry (ROTEM®) with standard plasmatic coagulation testing in paediatric surgery. Br J Anaesth. 2012;108(1):36–41. PMID: 22086509.CrossRefGoogle ScholarPubMed
Marques, MB, Tuncer, HH, Divers, SG, et al. Acute transient leukopenia as a sign of TRALI. Am J Hematol. 2005;80(1):90–1. PMID: 16138350.CrossRefGoogle ScholarPubMed
Mazzeffi, MA, Stone, ME. Perioperative management of von Willebrand disease: a review for the anesthesiologist. J Clin Anesth. 2011;23(5):418–26. PMID: 21741810.CrossRefGoogle ScholarPubMed
Mehra, T, Seifert, B, Bravo-Reiter, S, et al. Implementation of a patient blood management monitoring and feedback program significantly reduces transfusions and costs. Transfusion. 2015;55(12):2807–15. PMID: 26264557.CrossRefGoogle ScholarPubMed
Piel, FB, Steinberg, MH, Rees, DC. Sickle Cell Disease. N Engl J Med. 2017;376(16):1561–73.CrossRefGoogle ScholarPubMed
Toy, P, Popovsky, MA, Abraham, E, et al. Transfusion-related acute lung injury: definition and review. Crit Care Med. 2005;33(4):721–6. PMID: 15818095.CrossRefGoogle ScholarPubMed
Vogel, AM, Radwan, ZA, Cox, CS Jr., et al. Admission rapid thrombelastography delivers real-time “actionable” data in pediatric trauma. J Pediatr Surg. 2013;48(6):1371–6. PMID: 23845632.CrossRefGoogle ScholarPubMed

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