Book contents
- Fertility Preservation
- Fertility Preservation
- Copyright page
- Dedication
- Contents
- Contributors
- Foreword
- Foreword
- Preface
- Section 1 Introduction
- Chapter 1 The Evolution of the Assisted Reproduction Technologies
- Chapter 2 The Effect of Chemotherapy on the Human Reproductive System
- Chapter 3 The Effect of Radiotherapy on the Human Reproductive System
- Chapter 4 The Need for Fertility Preservation in Cancer Patients
- Section 2 Reproductive Biology and Cryobiology
- Section 3 Fertility Preservation in Cancer and Non-Cancer Patients
- Section 4 Fertility Preservation Strategies in the Male
- Section 5 Fertility Preservation Strategies in the Female: Medical/Surgical
- Section 6 Fertility Preservation Strategies in the Female: ART
- Section 7 Ovarian Cryopreservation and Transplantation
- Section 8 In Vitro Follicle Culture
- Section 9 New Research and Technologies
- Section 10 Ethical, Legal, and Religious Issues
- Index
- References
Chapter 3 - The Effect of Radiotherapy on the Human Reproductive System
from Section 1 - Introduction
Published online by Cambridge University Press: 27 March 2021
Book contents
- Fertility Preservation
- Fertility Preservation
- Copyright page
- Dedication
- Contents
- Contributors
- Foreword
- Foreword
- Preface
- Section 1 Introduction
- Chapter 1 The Evolution of the Assisted Reproduction Technologies
- Chapter 2 The Effect of Chemotherapy on the Human Reproductive System
- Chapter 3 The Effect of Radiotherapy on the Human Reproductive System
- Chapter 4 The Need for Fertility Preservation in Cancer Patients
- Section 2 Reproductive Biology and Cryobiology
- Section 3 Fertility Preservation in Cancer and Non-Cancer Patients
- Section 4 Fertility Preservation Strategies in the Male
- Section 5 Fertility Preservation Strategies in the Female: Medical/Surgical
- Section 6 Fertility Preservation Strategies in the Female: ART
- Section 7 Ovarian Cryopreservation and Transplantation
- Section 8 In Vitro Follicle Culture
- Section 9 New Research and Technologies
- Section 10 Ethical, Legal, and Religious Issues
- Index
- References
Summary
Cancer in childhood is rare. The most recent SEER Cancer Statistics Review, released in April 2018 and covering 2011–2015, shows that for ages 0–14 the incidence of all cancer sites was 16.4 per 100,000 children, with mortality 2.1 per 100,000. Five-year relative survival for the same age group was 83.8% for years 2008–2014 [1]. (Rates from the European Cancer Information System are similar but are currently available only to 2012.) As of 2015, 1 in 750 of the adult population of the United States was a long-term survivor of childhood cancer [1, 2]. Cancer is more common after puberty, with incidence rising from 12.9 for ages 5–9 to 23.3 for ages 15–19 in the United States for years 2011–2015 [1], and many of these patients will be cured by combination treatment, with surgery, chemotherapy, and radiotherapy. Long-term survivors are nevertheless at risk of developing a number of late sequelae [3], including impaired fertility, adverse pregnancy outcomes, and health problems in offspring [4–6].
- Type
- Chapter
- Information
- Fertility PreservationPrinciples and Practice, pp. 18 - 24Publisher: Cambridge University PressPrint publication year: 2021
References
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