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Chapter 10 - The Role of the Insula in Temporal Lobe Epilepsy and Temporal Lobe “Plus” Epilepsies

from Section 2 - The Spectrum of Epilepsies Involving the Insula

Published online by Cambridge University Press:  09 June 2022

By
Carmen Barba  and
Philippe Kahane
Edited by
Dang Nguyen ,
Jean Isnard  and
Philippe Kahane
Dang Nguyen
Affiliation:
Université de Montréal
Jean Isnard
Affiliation:
Claude Bernard University Lyon
Philippe Kahane
Affiliation:
Grenoble-Alpes University Hospital
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Summary

The role of the insula in temporal and temporal plus epilepsies has been poorly investigated. The insula is buried deep within the lateral sulcus and has dense connections with neighbored regions, thus limiting the usefulness of available non-invasive diagnostic tools, such as scalp EEG, SPECT, and 18FDG-PET. Also, clinical features related to the involvement of the insula might be misleading, thus making it mandatory to use invasive EEG recordings in most cases. In fact, only a primary involvement of the insula in the epileptogenic network may require to include this area in the resection to achieve seizure freedom. Using modern neurosurgical techniques, insular epilepsy surgery has proved to be safe and beneficial in carefully investigated cases; however, its efficacy remains to be fully elucidated.

Keywords

insular epilepsyepilepsy surgerystereo-EEGtemporal plus epilepsy
Type
Chapter
Information
Insular Epilepsies , pp. 110 - 117
Publisher: Cambridge University Press
Print publication year: 2022

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