Book contents
- Frontmatter
- Contents
- List of contributors
- 1 History of breast cancer therapy
- 2 Chemoprevention of breast cancer
- 3 Familial breast cancer
- 4 Hormone replacement therapy and breast cancer
- 5 Screening for breast cancer
- 6 The management of in situ breast cancer
- 7 Adjuvant systemic therapy
- 8 Adjuvant radiotherapy in the management of breast cancer
- 9 Predictors of response and resistance to medical therapy
- 10 Primary medical therapy in breast cancer
- 11 Medical therapy of advanced disease
- 12 Experimental approaches
- 13 The place of bisphosphonates in the management of breast cancer
- 14 Palliative care in breast cancer
- Index
1 - History of breast cancer therapy
Published online by Cambridge University Press: 06 January 2010
- Frontmatter
- Contents
- List of contributors
- 1 History of breast cancer therapy
- 2 Chemoprevention of breast cancer
- 3 Familial breast cancer
- 4 Hormone replacement therapy and breast cancer
- 5 Screening for breast cancer
- 6 The management of in situ breast cancer
- 7 Adjuvant systemic therapy
- 8 Adjuvant radiotherapy in the management of breast cancer
- 9 Predictors of response and resistance to medical therapy
- 10 Primary medical therapy in breast cancer
- 11 Medical therapy of advanced disease
- 12 Experimental approaches
- 13 The place of bisphosphonates in the management of breast cancer
- 14 Palliative care in breast cancer
- Index
Summary
History of surgery for breast cancer
Introduction
Breast cancer is an ancient disease and was described by the Egyptians 3000 years before Christ. Subsequently various articles about breast cancer and its treatment were written by Greek and Roman physicians. Surgery is the oldest method of treating breast cancer with different operations described which sometimes reflected beliefs held about its causes and natural history. However, a variety of ‘medical’ therapies have also been described, especially in the Middle Ages, which to the modern observer were more akin to witchcraft than the application of scientific knowledge to the treatment of the disease. Changing fashions in the treatment of breast cancer have reflected not only changes in beliefs regarding its pathogenesis but also a growth in knowledge about the disease as well as advances in science and technology. Thus four periods can be discerned in the evolution of treatment over the centuries. The first period could be described as the Empiric era of the pre-Galen period. Subsequently, breast cancer was regarded as a systemic disease and this characterized the Pessimistic period. By the eighteenth century, breast cancer was thought to be a local disease leading to the Optimistic era in which it was believed that larger operations than performed previously could eradicate the disease. By the twentieth century, knowledge about the biology of breast cancer had started to grow which led to a realization that breast cancer was a more complex disease than previously had been supposed and led to the establishment of the Realistic era in which we now find ourselves.
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- Chapter
- Information
- Medical Therapy of Breast Cancer , pp. 1 - 36Publisher: Cambridge University PressPrint publication year: 2003
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