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4 - Pain

Published online by Cambridge University Press:  08 February 2010

Aage R. Møller
Affiliation:
University of Texas, Dallas
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Summary

Introduction

Pain has many forms. It can be a warning of bodily injury that is important for avoiding injuries and therefore important for survival. Pain that is not caused by acute injuries can be a nuisance to a person or it can alter a person's entire life and affect his or her relatives in a major way.

Pain is purely subjective and it is often interpreted in an emotional context. There are great individual differences in the way pain is perceived. The reaction to pain often varies from time to time within the same individual. Pain that persists for a long time reduces the quality of life, a factor that unfortunately has not attracted the attention of the medical community that it deserves. Pain can be the cause of suicide, thus an extreme indication of its effect on the quality of life. Quality of life considerations are important in medical treatment (or lack of treatment), and likewise play an important role in pain management.

The intensity of pain is difficult to measure, and it is difficult to objectively assess the degree of pain that a certain individual may experience. An individual's perception of pain depends on a combination of factors such as the individual's emotional state, the circumstances under which the pain was acquired, and whether it is perceived as a threatening signal. The perception of pain is affected by factors such as arousal, attention, distraction and/or expectation.

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Publisher: Cambridge University Press
Print publication year: 2006

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References

Abbadie, C., , J. L. Brown, , C. R. Mantyh, and , A. I. Basbaum, Spinal Cord Substance P Receptor Immunoreactivity Increases in Both Inflammatory and Nerve Injury Models of Persistent Pain. Neuroscience, 1996. 70: pp. 201–209.CrossRefGoogle ScholarPubMed
Amaral, D. G., J. L. Price, A. Pitkanen, and S. T. Carmichael, Anatomical Organization of the Primate Amygdaloid Complex, in The Amygdala, , J. P. Aggleton, Editor. 1992, Wiley-Liss: New York. pp. 1–66.Google Scholar
Arnettz, B. B. and , B. Fjellner, Psychological Predictors of Neuroendocrine Responses to Mental Stress. J. Psychosomatic Res., 1986. 30: pp. 297–305.CrossRefGoogle Scholar
Bach, S., , M. F. Noreng, and , N. U. Tjellden, Phantom Limb Pain in Amputees During the First 12 Months Following Limb Amputation, after Preoperative Lumbar Epidural Blockade. Pain, 1988. 33: pp. 297–301.CrossRefGoogle ScholarPubMed
Bandler, R. and , M. T. Shipley, Columnar Organization in the Midbrain Periaqueductal Gray: Modules for Emotional Expression?Trends Neurosci., 1994. 17: pp. 379–389.CrossRefGoogle ScholarPubMed
Basbaum, A. I., , C. H. Clanton, and , H. L. Fields, Three Bulbospinal Pathways from the Rostral Medulla of the Cat: An Autoradiographic Study of Pain Modulating Systems. J. Comp. Neurol., 1978. 178: pp. 209–224.CrossRefGoogle ScholarPubMed
Basbaum, A. I. and , H. L. Fields, Endogenous Pain Control Systems: Brainstem Spinal Pathways and Endorphin Circuitry. Ann. Rev. Neurosci, 1984. 7(309–338).CrossRefGoogle ScholarPubMed
Bennett, R. M., Fibromyalgia, in Handbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill Livingstone: Edinburgh. pp. 579–601.Google Scholar
Berthoud, H. R. and , W. L. Neuhuber, Functional and Chemical Anatomy of the Afferent Vagal System. Autonomic Neurosci., 2000. 85(1–3): pp. 1–17.CrossRefGoogle ScholarPubMed
Beurrier, C., , B. Bioulac, , J. Audin, and Et Al., , High-Frequency Stimulation Produces a Transient Blockade of Voltage-Gated Currents in Subthalamic Neurons. J. Neurophys., 2001. 85: pp. 1351–1356.CrossRefGoogle ScholarPubMed
Blackburn-Munro, G. and , R. E. Blackburn-Munro, Chronic Pain, Chronic Stress and Depression: Coincidence or Consequence?J Neuroendocrinol, 2001. 13(12): pp. 1009–23.CrossRefGoogle ScholarPubMed
Boivie, J. and , B. A. Meyerson, A Correlative Anatomical and Clinical Study of Pain Suppression by Deep Brain Stimulation. Pain, 1982. 13: pp. 113–126.CrossRefGoogle ScholarPubMed
Boivie, J., Central Pain, in Textbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill Livingstone: Edinburgh. pp. 879–914.Google Scholar
Bolay, H. and , M. A. Moskowitz, Mechanisms of Pain Modulation in Chronic Syndromes. Neurology, 2002. 59(5 Suppl. 2): pp. S2–7.CrossRefGoogle ScholarPubMed
Bonomi, A. E., , R. Shikiar, and , M. W. Legro, Quality-of-Life Assessment in Acute, Chronic, and Cancer Pain: A Pharmacist's Guide. J. Am. Pharmaceutical Association., 2000. 40(3): pp. 402–16.Google ScholarPubMed
Borg-Stein, J. and S. A. Simon, Focused Review: Myofascial Pain. Arch. Phys. Med. Rehab., 2002. 83(3): pp. S40–7, S48–9.
Brodal, P., The Central Nervous System. 1998, Oxford University Press: New York.Google Scholar
Burstein, R., , M. F. Cutrer, and , D. Yarnitsky, The Development of Cutaneous Allodynia During a Migraine Attack Clinical Evidence for the Sequential Recruitment of Spinal and Supraspinal Nociceptive Neurons in Migraine. Brain, 2000. 123(8): pp. 1703–9.CrossRefGoogle ScholarPubMed
Cacace, A. T., , J. P. Cousins, , S. M. Parnes, , D. J. McFarland, , D. Semenoff, , T. Holmes, , C. Davenport, , K. Stegbauer, and , T. J. Lovely, Cutaneous-Evoked Tinnitus. Ii: Review of Neuroanatomical, Physiological and Functional Imaging Studies. Audiol. Neurotol., 1999. 4(5): pp. 258–268.CrossRefGoogle ScholarPubMed
Campbell, J., S. Raja, and R. Meyer, Painful Sequelae of Nerve Injury, in Proceedings of the Fifth World Congress on Pain, , R. Dubner, , G. Gebhart, and , M. Bond, Editors. 1988, Elsevier: Amsterdam. pp. 135–143.Google Scholar
Canavero, S., , V. Bonicalzi, , M. Dotta, , S. Vighetti, and , G. Asteggiano, Low-Rate Repetitive Tms Allays Central Pain. Neurol. Res., 2003. 25: pp. 151–152.CrossRefGoogle ScholarPubMed
Carli, G., Neuroplasticity and Clinical Pain. Progr. Brain Res., 2000. 129: pp. 325–330.CrossRefGoogle ScholarPubMed
Carstens, E., Altered Spinal Processing in Animal Models of Radicular and Neuropathic Pain, in Nervous System Plasticity and Chronic Pain, , J. Sandkühler, , B. Bromm, and , G. F. Gebhart, Editors. 2000, Elsevier: Amsterdam.Google Scholar
Cervero, F., Sensory Innervation of the Viscera: Peripheral Basis of Visceral Pain. Physiol. Rev., 1994. 74: pp. 95–138.CrossRefGoogle ScholarPubMed
Chabal, C., , L. Jacobson, , L. C. Russell, and , K. J. Burchiel, Pain Response to Perineuroneal Injection of Normal Saline, Epinephrine, and Lidocaine in Humans. Pain, 1992. 49: pp. 9–12.CrossRefGoogle Scholar
Chandler, M. J., , S. F. Hobbs, , D. C. Bolser, and , R. D. Foreman, Effects of Vagal Afferent Stimulation on Cervical Spinothalamic Tract Neurons in Monkeys. Pain, 1991. 44: pp. 81–87.CrossRefGoogle ScholarPubMed
Cherny, N. I. and R. K. Portenoy, Practical Issues in the Management of Cancer Pain, in Textbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill Livingstone: Edinburgh. pp. 1479–1522.Google Scholar
Cherny, N. I. and R. K. Portenoy, Cancer Pain: Principles of Assessment and Syndromes, in Textbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill Livingstone: Edinburgh. pp. 1017–1064.Google Scholar
Coderre, T. J., , J. Katz, , A. L. Vaccarino, and , R. Melzack, Contribution of Central Neuroplasticity to Pathological Pain: Review of Clinical and Experimental Evidence. Pain, 1993. 52: pp. 259–285.CrossRefGoogle ScholarPubMed
Coggeshall, R. E., , P. M. Dougherty, , C. M. Pover, and , S. M. Carlton, Is Large Myelinated Fiber Loss Associated with Hyperalgesia in a Model of Experimental Peripheral Neuropathy in the Rat. Pain, 1993. 52: pp. 233–242.CrossRefGoogle Scholar
Cohen, A. D., , R. Masalha, E. Medvedovsky, and D. A. Vardy, Brachioradial Pruritus: A Symptom of Neuropathy. J. Am. Acad. Dermatol., 2003. 48(6): pp. 825–8.CrossRefGoogle Scholar
Cousins, M. and I. Power, Acute and Postoperative Pain, in Textbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill Livingstone: Edinburgh. pp. 447–491.Google Scholar
Cousins, M. J. and , G. D. Philips, Acute Pain Management. Clinics in Critical Care Medicine. 1986, Churchill Livingstone: Edinburgh.
Cousins, M. J. and , P. O. Bridenbbaugh, Neural Blockade in Clinical Anesthesia and Management of Pain. 3rd ed. 1998, Lippincott-Raven: Philadelphia.Google Scholar
Crago, A., , J. C. Houk, and , W. Z. Rymer, Sampling of Total Muscle Force by Tendon Organs. J. Neurophys., 1982. 47: pp. 1069–1083.CrossRefGoogle ScholarPubMed
Craig, A. D., , M. C. Bushnell, , E. T. Zang, and , A. Blomquist, A Thalamic Nuclei Specific for Pain and Temperature. Nature, 1994. 372(6508): pp. 770–3.CrossRefGoogle ScholarPubMed
Craig, A. D. and J. O. Dostrovsky, Medulla to Thalamus, in Textbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill-Livingstone: Edinburgh. pp. 183–214.Google Scholar
Craig, A. D., Spinothalamic Lamina I Neurons Sensitive to Histamine: A Central Pathway for Itch. Nat. Neurosci., 2001. 4(1): pp. 72–7.Google Scholar
Crowley, W. R., , J. F. Rodriguez-Sierra, and , B. R. Komisaruk, Analgesia Induced by Vagina Stimulation in Rats Is Apparently Independent of a Morphine-Sensitive Process. Psychopharmacology, 1977. 54(3): pp. 223–5.CrossRefGoogle ScholarPubMed
Dahlöf, C. G. H., Management of Primary Headaches: Current and Future Aspects, in Pain 2002 – an Updated Review: Refresher Course Syllabus, , M. A. Giamberardino, Editor. 2002, International Association for the Study of Pain Press: Seattle.Google Scholar
Devor, M., The Pathophysiology of Damaged Peripheral Nerves, in Textbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1994, Churchill Livingstone: Edinburgh. pp. 79–100.Google Scholar
Devor, M. and Z. Seltzer, Pathophysiology of Damaged Nerves in Relation to Chronic Pain, in Textbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill Livingstone: Edinburgh. pp. 129–164.Google Scholar
Dickenson, A. H., N-methyl-D-aspartate Receptors Antagonists as an Analgesic. Prog. in Pain Res. and Management, 1994. 1: pp. 173–187.Google Scholar
Dickenson, A. H., Balance between Excitatory and Inhibitory Events in the Spinal Cord and Chronic Pain. Prog. Brain Res., 1996. 110: pp. 225–231.CrossRefGoogle Scholar
Doron, N. N. and , J. E. Ledoux, Cells in the Posterior Thalamus Project to Both Amygdala and Temporal Cortex: A Quantitative Retrograde Double-Labeling Study in the Rat. J. Comp. Neurol., 2000. 425: pp. 257–274.3.0.CO;2-Y>CrossRefGoogle ScholarPubMed
Doubell, T. P., R. J. Mannion, and C. J. Woolf, The Dorsal Horn: State-Dependent Sensory Processing, Plasticity and the Generation of Pain, in Handbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill Livingstone: Edinburgh. pp. 165–181.Google Scholar
Drzezga, A., , U. Darsow, , R. D. Treede, , H. Siebner, , M. Frisch, , F. Munz, , F. Weilke, , J. Ring, , M. Schwaiger, and , P. Bartenstein, Central Activation by Histamine-Induced Itch: Analogies to Pain Processing: A Correlational Analysis of O-15 H2O Positron Emission Tomography Studies. Pain, 2001. 92(1–2): pp. 295–305.CrossRefGoogle ScholarPubMed
Farina, S., , M. Tinazzi, , D. Pera, and , M. Valeriani, Pain-Related Modulation of the Human Motor Cortex. Neurol. Res., 2003. 25: pp. 130–142.CrossRefGoogle ScholarPubMed
Fields, H. L. and A. I. Basbaum, Central Nervous System Mechanism of Pain Modulation, in Textbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill Livingstone: Edinburgh. pp. 309–329.Google Scholar
Freund, B. J. and , M. Schwartz, Relief of Tension-Type Headache Symptoms in Subjects with Temporomandibular Disorders Treated with Botulinum Toxin-A. Headache, 2002. 42(10): pp. 1033–37.CrossRefGoogle ScholarPubMed
Fu, Q. G., , M. J. Chandler, , D. L. McNeill, and , R. D. Foreman, Vagal Afferent Fibers Excite Upper Cervical Neurons and Inhibit Activity of Lumbar Spinal Cord Neurons in the Rat. Pain, 1992. 51: pp. 91–100.Google ScholarPubMed
Fusco, B. M., , S. Marabini, , C. A. Maggi, , G. Fiore, and , P. Geppetti, Preventive Effect of Repeated Nasal Applications of Capsaicin in Cluster Headache. Pain, 1994(59): pp. 321–325.
Garonzik, I. M., , S. E. Hua, , S. Ohara, and , F. A. Lenz, Intraoperative Microelectrode and Semi-Microelectrode Recording During the Physiological Localization of the Thalamic Nucleus Ventral Intermediate. Movement Disorders, 2002. 17(3).CrossRefGoogle ScholarPubMed
Gebhart, G. F. and , A. Randich, Vagal Modulation of Nociception. Am. Pain Soc. J., 1992. 1: pp. 26–32.Google Scholar
Gerhart, K. D., , R. P. Yezierski, and , G. J. Giesler, Inhibitory Receptive Fields of Primate Spinothalamic Tract Cells. J. Neurophys, 1981. 46: pp. 1309–25.CrossRefGoogle ScholarPubMed
Gorecki, J., , T. Hirayama, , J. O. Dostrovsky, , R. R. Tasker, and , F. A. Lenz, Thalamic Stimulation and Recording in Patients with Deafferentation and Central Pain. Stereotactic & Functional Neurosurgery, 1989. 52(2–4): pp. 219–26.CrossRefGoogle ScholarPubMed
Graven-Nielsen, T. and , S. Mense, The Peripheral Apparatus of Muscle Pain: Evidence from Animal and Human Studies. Clin. J. Pain., 2001. 17(1): pp. 2–10.CrossRefGoogle ScholarPubMed
Grevert, P., , L. H. Albert, and , A. Goldstein, Partial Antagonism of Placebo Analgesia by Naloxone. Pain, 1983. 16: pp. 129–143.CrossRefGoogle ScholarPubMed
Gybels, J. M. and R. R. Tasker, Central Neurosurgery, in Textbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill Livingstone: Edinburgh. pp. 1307–1339.Google Scholar
Hall, T. M. and , R. L. Elvey, Nerve Trunk Pain: Physical Diagnosis and Treatment. Manual Therapy, 1999. 4(2): pp. 63–73.CrossRefGoogle ScholarPubMed
Hammond, D. L., , G. M. Tyce, and , T. L. Yaksh, Efflux of 5-Hydroxytryptamine and Noradrenaline into Spinal Cord Superfusates During Stimulation of the Rat Medulla. J. Physiol., 1985. 359: pp. 151–162.CrossRefGoogle ScholarPubMed
Han, S. C. and , P. Harrison, Myofascial Pain Syndrome and Trigger-Point Management. Regional Anesthesia, 1997. 95(2): pp. 89–101.CrossRefGoogle Scholar
Handwerker, H. O., W. Magerl, F. Klemm, and R. A. Westerman, Quantitative Evaluation of Itch Sensation, in Fine Afferent Nerve Fibers and Pain, , R. F. Schmidt, , H.-G. Schaible, and , C. Vahle-Hinz, Editors. 1987, VCH Verlagsgesellschaft: Germany. pp. 462–473.Google Scholar
Hassenbusch, S. J., , P. K. Pillay, and , G. H. Barnett, Radiofrequency Cingulotomy for Intractable Cancer Pain Using Stereotaxis Guided by Magnetic Resonance Imaging. Neurosurg., 1990. 27(2): pp. 220–3.CrossRefGoogle ScholarPubMed
Haws, C. M., , A. M. Williamson, and , H. L. Fields, Putative Nociceptive Modulatory Neurons in the Dorsolateral Pontomesencephalic Reticular Formation. Brain Res., 1989. 483: pp. 272–282.CrossRefGoogle ScholarPubMed
Herbert, H. and , C. B. Saper, Organization of Medullary Adrenergic and Noradrenergic Projections to Periaqueductal Gray Matter in the Rat. J. Comp. Neurol., 1992. 315: pp. 34–52.CrossRefGoogle ScholarPubMed
Herndon, R. M., Handbook of Neurologic Rating Scales. 1997, Demos Vermande New York: New York.Google Scholar
Hirato, M., , K. Watanabe, , A. Takahashi, , N. Hayase, , S. Horikoshi, , T. Shibaski, and , C. Ohye, Pathophysiology of Central (Thalamic) Pain: Combined Change of Sensory Thalamus with Cerebral Cortex around Central Sulcus. Stereotact. Funct. Neurosurg., 1994. 62(1–4): pp. 300–3.CrossRefGoogle ScholarPubMed
Hitzelberger, W. E. and , R. M. Witten, Abnormal Myelograms in Asymptomatic Patients. J. Neurosurg., 1968. 28: pp. 204–6.CrossRefGoogle Scholar
Hong, C. Z., Pathophysiology of Myofascial Trigger Point. Journal of the Formosan Medical Association, 1996. 95(2): pp. 93–104.Google ScholarPubMed
Hong, C. Z. and , D. G. Simons, Pathophysiologic and Electrophysiologic Mechanisms of Myofascial Trigger Points. Arch Phys. Med. Rehab., 1998. 79(7): pp. 863–72.CrossRefGoogle ScholarPubMed
Hua, S. E., , I. M. Garonzik, , J. I. Lee, and , F. A. Lenz, Microelectrode Studies of Normal Organization and Plasticity of Human Somatosensory Thalamus. J. Clin. Neurophysiol., 2000. 17(6): pp. 559–74.CrossRefGoogle ScholarPubMed
Hubbard, D. R. and , G. M. Berkoff, Myofascial Trigger Points Show Spontaneous Needle Electromyography Activity. Spine, 1993. 18(13): pp. 1803–7.CrossRefGoogle Scholar
Inui, K., , D. T. Tran, , M. Qiu, , X. Wang, , M. Hoshiyama, and , R. Kakigi, Pain-Related Magnetic Fields Evoked by Intra-Epidermal Electrical Stimulation in Humans. Clin. Neurophysiol., 2002. 113: pp. 298–304.CrossRefGoogle ScholarPubMed
Jaeger, B., Differential Diagnosis and Management of Craniofacial Pain, in Endodontics, , J. I. Ingle and , L. K. Bakland, Editors. 1994, Williams and Wilkins: Baltimore, MD. pp. 550–607.Google Scholar
Jänig, W., The Puzzle of “Reflex Sympathetic Dystrophy”: Mechanisms, Hypotheses, Open Questions, in Reflex Sympathetic Dystrophy: A Reappraisal, , W. Jänig and , M. Stanton-Hicks, Editors. 1996, International Association for the Study of Pain Press: Seattle. pp. 1–24.Google Scholar
Jänig, W. and , M. Stanton-Hicks, Reflex Sympathetic Dystrophy – a Reapraisal. 1996, ISAP: Seattle.Google Scholar
Jänig, W., , S. G. Khasar, , J. D. Levine, and , F. J.-P. Miao, The Role of Vagal Visceral Afferents in the Control of Nociception. The Biological Basis for Mind Body Interaction. Prog. Brain Res., 2000. 122: pp. 271–285.Google Scholar
Jastreboff, P. J., Phantom Auditory Perception (Tinnitus): Mechanisms of Generation and Perception. Neurosci. Res., 1990. 8: pp. 221–254.CrossRefGoogle ScholarPubMed
Jastreboff, P. J., Tinnitus as a Phantom Perception: Theories and Clinical Implications, in Mechanisms of Tinnitus, , J. A. Vernon and , A. R. M⊘ller, Editors. 1995, Allyn & Bacon: Boston. pp. 73–93.Google Scholar
Jensen, R., Peripheral and Central Mechanisms in Tension-Type Headache: An Update. Cephalalgia, 2003. 23(Suppl. 1): pp. 49–52.CrossRefGoogle ScholarPubMed
Jinks, S. L. and , E. Carstens, Superficial Dorsal Horn Neurons Identified by Intracutaneous Histamine: Chemonociceptive Responses and Modulation by Morphine. J. Neurophys., 2000. 84: pp. 616–627.CrossRefGoogle ScholarPubMed
Jinks, S. L. and , E. Carstens, Responses of Superficial Dorsal Horn Neurons to Intradermal Serotonin and Other Irritants: Comparison with Scratching Behavior. J. Neurophys., 2002. 87(3): pp. 1280–9.CrossRefGoogle ScholarPubMed
Kakigi, R., , T. Diep, , Y. Qiu, , X. Wang, , T. B. Nguyen, , K. Inui, , S. Watanabe, and , M. Hoshiyama, Cerebral Responses Following Stimulation of Unmyelinated C-Fibers in Humans: Eletro- and Magneto-Encephalographic Study. Neurosci. Res., 2003.CrossRefGoogle Scholar
Kannel, W. B. and , R. D. Abbott, Incidence and Prognosis of Unrecognized Myocardial Infarction. N. Eng. J. Med., 1984. 311: pp. 1144–1147.CrossRefGoogle ScholarPubMed
Katayama, Y., , T. Tsubokawa, and , T. Yamamoto, Chronic Motor Cortex Stimulation for Central Deafferentation Pain: Experience with Bulbar Pain Secondary to Wallenberg Syndrome. Stereotact. Funct. Neurosurg., 1995. 34: pp. 42–48.Google Scholar
Keay, K.., and , R. Bandler, Parallel Circuits Mediating Distinct Emotional Coping Reactions to Different Types of Stress. Neurosci Biobehav Rev, 2001. 25(7–8): pp. 669–78.CrossRefGoogle ScholarPubMed
Keay, K. A., , C. I. Clement, , A. Depaulis, and , R. Bandler, Different Representations of Inescapable Noxious Stimuli in the Periaqueductal Gray and Upper Cervical Spinal Cord of Freely Moving Rats. Neurosci Lett, 2001. 313(1–2): pp. 17–20.CrossRefGoogle ScholarPubMed
Kilgard, M. P. and , M. M. Merzenich, Cortical Map Reorganization Enabled by Nucleus Basalis Activity. Science, 1998. 279: pp. 1714–1718.CrossRefGoogle ScholarPubMed
Kirchner, A., , F. Birklein, , H. Stefan, and , H. O. Handwerker, Left Vagus Nerve Stimulation Suppresses Experimentally Induced Pain. Neurology, 2000. 55(8): pp. 1167–71.CrossRefGoogle ScholarPubMed
Kjellberg, F. and , M. R. Tramer, Pharmacological Control of Opioid-Induced Pruritus: A Quantitative Systematic Review of Randomized Trials. Europ. J. Anaesthesiol., 2001. 18(6): pp. 346–57.CrossRefGoogle ScholarPubMed
Knighton, R. S. and , P. R. Dumke, Pain. 1966, Little Brown: Boston.Google Scholar
Koch, B. D., , G. F. Faurot, , J. R. McGuirk, , D. E. Clarke, and , J. C. Hunter, Modulation of Mechano-Hyperalgesia by Clinically Effective Analgesics in Rats with Peripheral Mononeuropathy. Analgesia, 1996. 2: pp. 157–164.Google Scholar
Koerber, H. R., , K. Mirnics, , A. M. Kavookjian, and , A. R. Light, Ultrastructural Analysis of Ectopic Synaptic Boutons Arising from Peripherally Regenerated Primary Afferent Fibers. J. Neurophysiol, 1999. 81: pp. 1636.CrossRefGoogle ScholarPubMed
Kohama, I., , K. Ishikawa, and , J. D. Kocsis, Synaptic Reorganization in the Substantia Gelatinosa after Peripheral Nerve Neuroma Formation: Aberrant Innervation of Lamina II Neurons by Beta Afferents. J. Neurosci., 2000. 20: pp. 1538–1549.CrossRefGoogle Scholar
Komisaruk, B. R., , C. A. Gerdes, and , B. Whipple, ‘Complete’ Spinal Cord Injury Does Not Block Perceptual Responses to Genital Self-Stimulation in Women. Arch. Neurol., 1997. 54(12): pp. 1513–20.CrossRefGoogle Scholar
Kruit, M. C., , M. A. Buchem, , P. A. Hofman, , J. T. Bakkers, , G. M. Terwindt, , M. D. Ferrari, and , L. J. Launer, Migraine as a Risk Factor for Subclinical Brain Lesions. JAMA, 2004. 291(4): pp. 427–34.CrossRefGoogle ScholarPubMed
Kugelberg, E., Activation of Human Nerves by Ischemia. Arch. Neurol. Psychiat., 1948. 60: pp. 140–152.CrossRefGoogle ScholarPubMed
Kuraishi, Y., T. Yamaguchi, and T. Miyamoto, Itch-Scratch Responses Induced by Opioids through Central Mu Opioid Receptors in Mice. 2000. 7(3): pp. 248–52.
Kwiat, G. C. and , A. I. Basbaum, The Origin of Brainstem Noradrenergic and Serotonergic Projections to the Spinal Cord Dorsal Horn in the Rat. Somatosensory and Motor Res., 1992. 9: pp. 157–173.CrossRefGoogle ScholarPubMed
Layzer, R. B., Muscle Pain, Cramps, and Fatigue, in Myology, 2nd Ed, , A. G. Engel and , C. Franzini-Armstrong, Editors. 1994, McGraw-Hill: New York. pp. 1754–1768.Google Scholar
LeDoux, J. E., Brain Mechanisms of Emotion and Emotional Learning. Curr. Opin. Neurobiol., 1992. 2: pp. 191–197.CrossRefGoogle ScholarPubMed
Lenz, F. A., , R. H. Gracely, , A. J. Romanoski, , E. J. Hope, , L. H. Rowland, and , P. M. Dougherty, Stimulation in the Human Somatosensory Thalamus Can Reproduce Both the Affective and Sensory Dimensions of Previously Experienced Pain. Nature Medicine, 1995. 1(9): pp. 910–3.CrossRefGoogle ScholarPubMed
Lenz, F. A., , R. H. Gracely, , F. H. Baker, , R. T. Richardson, and , P. M. Dougherty, Reorganization of Sensory Modalities Evoked by Microstimulation in Region of the Thalamic Principal Sensory Nucleus in Patients with Pain Due to Nervous System Injury. J. Comp. Neurol., 1998. 399(1): pp. 125–38.3.0.CO;2-G>CrossRefGoogle ScholarPubMed
Lenz, F. A., , M. Rios, , A. Zirh, , D. Chau, , G. Krauss, and , R. P. Lesser, Painful Stimuli Evoke Potentials Recorded over the Human Anterior Cingulate Gyrus. J. Neurophys., 1998. 79(4): pp. 2231–4.CrossRefGoogle ScholarPubMed
Levine, J. D., , N. C. Gordon, and , H. L. Fields, The Mechanism of Placebo Analgesia. Lancet, 1978: pp. 654–657.CrossRefGoogle ScholarPubMed
Liu, H., , C. R. Mantyh, and , A. I. Basbaum, N-methyl-D-aspartate-Receptor Regulation of Substance-P Release from Primary Nociceptors. Nature, 1997. 386: pp. 721–724.CrossRefGoogle Scholar
Loder, E. and , D. Biondi, Use of Botulinum Toxins for Chronic Headaches: A Focused Review. Clin. J. Pain, 2002. 18(6): pp. 169–176.CrossRefGoogle ScholarPubMed
Loh, L. and , P. W. Nathan, Painful Peripheral States and Sympathetic Blocks. J. Neurol. Neurosurg. Psychiat., 1978. 41: pp. 664–671.CrossRefGoogle ScholarPubMed
Long, D. M., Chronic Back Pain, in Handbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill Livingstone: Edinburgh. pp. 539–538.Google Scholar
Lumb, B. M., Inescapable and Escapable Pain Is Represented in Distinct Hypothalamic-Midbrain Circuits: Specific Roles of Ad- and C-Nociceptors. Exp. Physiol., 2002. 87: pp. 281–86.CrossRefGoogle Scholar
Malmberg, A. B., Central Changes, in Pain in Peripheral Nerve Diseases. Pain Headache, , C. Sommer, Editor. 2001, Karger: Basel. pp. 149–167.Google Scholar
Mason, P., , S. A. Back, and , H. L. Fields, A Confocal Laser Microscopic Study of Enkephalin-Immunoreactive Appositions onto Physiologically Identified Neurons in the Rostral Ventromedial Medulla. J. Neuro. Sci., 1992. 12: pp. 4023–4036.Google ScholarPubMed
Massey, E. W. and , J. M. Massey, Forearm Neuropathy and Pruritus. Southern Medical J., 1986. 79(10): pp. 1259–1260.CrossRefGoogle ScholarPubMed
Mathews, E. S. and , S. J. Scrivani, Percutaneous Stereotactic Radiofrequency Thermal Rhizotomy for the Treatment of Trigeminal Neuralgia. Mount Sinai J. Med., 2000. 67(4): pp. 288–99.Google ScholarPubMed
Mäurer, M. and K. Reiners, Mononeuropathies, in Pain in Peripheral Nerve Diseases. Pain Headache, , C. Sommer, Editor. 2001, Karger: Basel. pp. 37–52.Google Scholar
McDonald, A. J., Cortical Pathways to the Mammalian Amygdala. Progr. Neurobiol., 1998. 55(3): pp. 257–332.CrossRefGoogle ScholarPubMed
McQuay, H., Do Preemptive Treatments Provide Better Pain Control?, in Progr. Pain Res. Management, , G. F. Gebhart, , D. L. Hammond, and , T. Jensen, Editors. 1994, International Association for the Study of Pain Press: Seattle, WA. pp. 709–723.Google Scholar
Melzack, R. and , P. D. Wall, Pain Mechanisms: A New Theory. Science, 1965. 150: pp. 971–979.CrossRefGoogle ScholarPubMed
Melzack, R., Phantom Limbs. Sci. Am., 1992. 266: pp. 120–126.CrossRefGoogle ScholarPubMed
Mendell, L. M., Modifiability of Spinal Synapses. Physiol Rev, 1984. 64: pp. 260–324.CrossRefGoogle ScholarPubMed
Mense, S. and Bradykinin, M. H.-Induced Modulation of the Response Behaviour of Different Types of Feline Group Iii and Iv Muscle Receptors. J. Physiol., 1988. 398: pp. 49–63.CrossRefGoogle ScholarPubMed
Mense, S., Referral of Muscle Pain: New Aspects. Am. Pain Soc. J., 1994. 3: pp. 1–9.Google Scholar
Merskey, H. and N. Bogduk, Classification of Chronic Pain. 1994, International Association for the Study of Pain Press: Seattle. pp. 1–222.
Meyerson, B. A., , U. Lindblom, , B. Linderoth, and , G. Lind, Motor Cortex Stimulation as Treatment of Trigeminal Neuropathic Pain. Acta Neurochir. – Suppl., 1993. 58: pp. 105–3.Google ScholarPubMed
Meyerson, B. A. and , B. Linderoth, Mechanism of Spinal Cord Stimulation in Neuropathic Pain. Neurol. Res., 2000. 22: pp. 285–292.CrossRefGoogle Scholar
M⊘ller, A. R., , M. B. M⊘ller, and , M. Yokota, Some Forms of Tinnitus May Involve the Extralemniscal Auditory Pathway. Laryngoscope, 1992. 102: pp. 1165–1171.CrossRefGoogle Scholar
M⊘ller, A. R., Cranial Nerve Dysfunction Syndromes: Pathophysiology of Microvascular Compression, in Neurosurgical Topics Book 13, ‘Surgery of Cranial Nerves of the Posterior Fossa,’ Chapter 2, , D. L. Barrow, Editor. 1993, American Association of Neurological Surgeons: Park Ridge. IL. pp. 105–129.Google Scholar
M⊘ller, A. R., Similarities between Chronic Pain and Tinnitus. Am. J. Otol., 1997. 18: pp. 577–585.Google Scholar
M⊘ller, A. R. and , T. Pinkerton, Temporal Integration of Pain from Electrical Stimulation of the Skin. Neurol. Res, 1997. 19: pp. 481–488.CrossRefGoogle Scholar
M⊘ller, A. R., Sensory Systems: Anatomy and Physiology. 2003, Academic Press: Amsterdam.Google Scholar
M⊘ller, A. R., Pathophysiology of Tinnitus, in Otolaryngologic Clinics of North America, , A. Sismanis, Editor. 2003, W. B. Saunders: Amsterdam. pp. 249– 266.Google Scholar
Montgomery, E. B. J. and , K. B. Baker, Mechanisms of Deep Brain Stimulation and Future Technical Developments. Neurol Res, 2000. 22: pp. 259–66.Google ScholarPubMed
Morgan, M. M. and , P. Carrive, Activation of Periaqueductal Gray Reduces Locomotion but Not Mean Arterial Blood Pressure in Awake, Freely Moving Rats. Neuroscience, 2001. 102: pp. 905–10.CrossRefGoogle Scholar
Narins, C. R., , W. Zareba, , A. J. Moss, , R. E. Goldstein, and , W. J. Hall, Clinical Implications of Silent Versus Symptomatic Exercise-Induced Myocardial Ischemia in Patients with Stable Coronary Disease. J. Am. Col. Cardiol., 1997. 29(4): pp. 756–63.CrossRefGoogle ScholarPubMed
Nasreddine, Z. S. and , J. L. Saver, Pain after Thalamic Stroke: Right Diencephalic Predominance and Clinical Features in 180 Patients. Neurology, 1997. 48(5): pp. 1196–9.CrossRefGoogle ScholarPubMed
Nathan, P. W., On the Pathogenesis of Causalgia in Peripheral Nerve Injuries. Brain, 1947. 70: pp. 145–70.CrossRefGoogle ScholarPubMed
Neri Serneri, G. G., , M. Boddi, , L. Arata, , C. Rostagno, , P. Dabizzi, , M. Coppo, , M. Bini, , S. Lazzerini, , A. Dagianti, and , G. F. Gensini, Silent Ischemia in Unstable Angina Is Related to an Altered Cardiac Norepinephrine Handling. Circulation, 1993. 87(6): pp. 1928–37.CrossRefGoogle Scholar
Newham, D. J. and K. R. Mills, Muscles, Tendons and Ligaments, in Handbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill Livingstone: Edinburgh. pp. 517–538.Google Scholar
Nguyen, J. P., , Y. Keravel, , A. Feve, , T. Uchiyama, , P. Cesaro, , C. Le Guerinel, and , B. Pollin, Treatment of Deafferentation Pain by Chronic Stimulation of the Motor Cortex. Report of a Series of 20 Cases. Acta Neurochiur. Suppl. (Wien), 1997. 8(54–60).Google Scholar
Oppenheimer, S. M., , N. Kulshreshtha, , F. A. Lenz, , Z. Zhang, , L. H. Rowland, and , P. M. Dougherty, Distribution of Cardiovascular Related Cells within the Human Thalamus. Clinical Autonomic Research., 1998. 8(3): pp. 173–9.CrossRefGoogle ScholarPubMed
Pagni, C. A., , M. Lanotte, and , S. Canavero, How Frequent Is Anesthesia Dolorosa Following Spinal Posterior Rhizotomy? A Retrospective Analysis of Fifteen Patients. Pain, 1993. 54(3): pp. 323–7.CrossRefGoogle ScholarPubMed
Pillay, P. K. and , S. J. Hassenbusch, Bilateral Mri-Guided Stereotactic Cingulotomy for Intractable Pain. Stereotac. & Funct. Neurosurg., 1992. 59(1–4): pp. 33–8.CrossRefGoogle ScholarPubMed
Podivinsky, F., Torticollis, in Handbook of Clinical Neurology, Diseases of the Basal Ganglia, , P. J. Vinken and , G. W. Bruyn, Editors. 1968, North Holland Publishing Co: New York. pp. 567–603.Google Scholar
Porta, M., A Comparative Trial of Botulinum Toxin Type A and Methylprednisolone for the Treatment of Myofascial Pain Syndrome and Pain from Chronic Muscle Spasm. Pain, 2000. 85(1): pp. 101–105.CrossRefGoogle ScholarPubMed
Price, D. D., Psychological and Neural Mechanisms of Pain. 1988, Raven: New York.Google Scholar
Price, D. D., , S. Long, and , C. Huitt, Sensory Testing of Pathophysiological Mechanisms of Pain in Patients with Reflex Sympathetic Dystrophy. Pain, 1992. 49: pp. 163–173.CrossRefGoogle ScholarPubMed
Procacci, P., , M. Zoppi, , L. Padeletti, and , M. Maresca, Myocardial Infarction without Pain. A Study of the Sensory Function of the Upper Limbs. Pain, 1976. 2: pp. 309–313.CrossRefGoogle Scholar
Procaccio, P. and M. Zoppi, Pathophysiology and Clinical Aspects of Visceral and Referred Pain, in Proceedings of the Third World Congress on Pain, , J. J. Bonica, , U. Lindblom, and , A. Iggo, Editors. 1983, Raven Press: New York. pp. 643– 658.Google Scholar
Procacci, P., M. Zoppi, and M. Maresca, Heart, Vascular and Haemopathic Pain, in Textbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill Livingstone: Edinburgh. pp. 621–639.Google Scholar
Quasthoff, S. and C. Sommer, Peripheral Mechanisms, in Pain in Peripheral Nerve Diseases. Pain Headache, , C. Sommer, Editor. 2001, Karger: Basel. pp. 110–148.Google Scholar
Quinn, C., , C. Chandler, and , A. Moraska, Massage Therapy and Frequency of Chronic Tension Headaches. Am. J. Public Health, 2002. 92(10): pp. 1657–61.CrossRefGoogle ScholarPubMed
Raja, S. N., , J. N. Campbell, and , R. A. Meyer, Evidence for Different Mechanisms of Primary and Secondary Hyperalgesia Following Heat Injury to the Glabrous Skin. Brain, 1984. 107: pp. 1791–1188.CrossRefGoogle ScholarPubMed
Randich, A. and , G. F. Gebhart, Vagal Afferent Modulation of Nociception. Brain Res. Rev., 1992. 17: pp. 77–99.CrossRefGoogle ScholarPubMed
Rapkin, A. J., Chronic Pelvic Pain, in Textbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill Livingstone: Edinburgh. pp. 641–659.Google Scholar
Reichling, D. B. and , A. I. Basbaum, Contribution of Brainstem Gamma aminobutyric acidergic Circuitry to Descending Antinociceptive Controls: I. Gamma aminobutyric acid-Immunoreactive Projection Neurons in the Periaquaductal Gray and Nucleus Raphe Magnus. J. Comp. Neurol., 1990. 302: pp. 303–377.Google Scholar
Rexed, B. A., Cytoarchitectonic Atlas of the Spinal Cord. J. Comp. Neurol., 1954. 100: pp. 297–379.CrossRefGoogle ScholarPubMed
Rocco, A. G., Radiofrequency Lumbar Sympatholysis. Regional Anesthesia, 1995. 20: pp. 3–12.Google ScholarPubMed
Rosenow, J. M., , A. Y. Mogilner, , A. Ahmed, and , A. R. Rezai, Deep Brain Stimulation for Movement Disorders. Neurol. Res., 2004. 26: pp. 9–20.CrossRefGoogle ScholarPubMed
Roychowdhury, S. M. and , H. L. Fields, Endogenous Opioids Acting at a Medullary Mμ-Opioid Receptors Contribute to the Behavioral Antinociception Produced by Gamma aminobutyric acid Antagonism in the Midbrain Periaqueductal Gray. Neuroscience, 1996. 74: pp. 863–72.CrossRefGoogle Scholar
Ruch, T. C., Pathophysiology of Pain, in The Brain and Neural Function, , T. C. Ruch and , H. D. Patton, Editors. 1979, W. B. Saunders: Philadelphia. pp. 272–324.Google Scholar
Sandkühler, J., J. Benrath, C. Brechtel, R. Ryuscheweyh, and B. Heinke, Synaptic Mechanisms of Hyperalgesia, in Nervous System Plasticity and Chronic Pain, , J. Sandkühler, , B. Bromm, and , G. F. Gebhart, Editors. 2000, Elsevier: Amsterdam. pp. 81–100.Google Scholar
Sandroni, P., Central Neuropathic Itch: A New Treatment Option? Neurology, 2002. 59: pp. 778–780.CrossRefGoogle ScholarPubMed
Sastry, B. R., Substance P Effects on Spinal Nociceptive Neurons. Life Sci., 1979. 24: pp. 2178.CrossRefGoogle Scholar
Scadding, J. W., , P. D. Wall, , C. B. Parry, and , D. M. Brooks, Clinical Trial of Propranolol in Post-Traumatic Neuralgia. Pain, 1982: pp. 283–92.CrossRefGoogle ScholarPubMed
Scadding, J. W., Complex Regional Pain Syndrome, in Textbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill Livingstone: Edinburgh. pp. 835–849.Google Scholar
Schäfers, M. and C. Sommer, Polyneuropathies, in Pain in Peripheral Nerve Diseases. Pain Headache, , C. Sommer, Editor. 2001, Karger: Basel. pp. 53–108.Google Scholar
Schmelz, M., Itch – Mediators and Mechanisms. J. Dermatol. Sci., 2002. 28: pp. 91–96.CrossRefGoogle ScholarPubMed
Sessle, B. J., Recent Development in Pain Research: Central Mechanism of Orofacial Pain and Its Control. J. Endodon., 1986. 12: pp. 435–444.CrossRefGoogle Scholar
Shyu, B. C., , N. Danielsen, , S. A. Andersson, and , L. B. Dahlin, Effects of Sympathetic Stimulation on C-Fiber Response after Peripheral Nerve Compression: An Experimental Study in the Rabbit Common Peroneal Nerve. Acta Physiol. Scand, 1990. 140: pp. 237–243.CrossRefGoogle ScholarPubMed
Siegfried, J., Sensory Thalamic Neurostimulation for Chronic Pain. Pacing & Clin. Electrophysiol., 1987. 10(2): pp. 209–210.CrossRefGoogle ScholarPubMed
Simone, D. A., , L. S. Sorkin, , U. Oh, , J. M. Chung, , C. Owens, , R. H. Lamotte, and , W. D. Willis, Neurogenic Hyperalgesia: Central Neural Correlates in Responses of Spinothalamic Tract Neurons. J. Neurophys., 1991. 66: pp. 228–246.CrossRefGoogle ScholarPubMed
Simons, D. G. and , S. Mense, Understanding and Measurement of Muscle Tone as Related to Clinical Muscle Pain. Pain, 1998. 75(1)(1): pp. 1–17.CrossRefGoogle ScholarPubMed
Sindou, M. and , D. Jeanmonod, Microsurgical-Drez-Otomy for Treatment of Spasticity and Pain in the Lower Limbs. Neurosurgery, 1989. 24: pp. 655–670.CrossRefGoogle ScholarPubMed
Sindrup, S. H. and , T. S. Jensen, Efficacy of Pharmacological Treatments of Neuropathic Pain: An Update and Effect Related to Mechanism of Drug Action. Pain, 1999. 83: pp. 389–400.CrossRefGoogle ScholarPubMed
Sola, A. E., , M. L. Rodenberg, and , B. B. Getty, Incidence of Hypersensitive Areas in the Neck and Shoulder Muscles. Am. J. Phys. Med., 1955. 34: pp. 585–90.Google Scholar
Sola, A. E., Upper Extremity Pain, in Handbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill Livingstone: Edinburgh. pp. 559–578.Google Scholar
Sommer, C., Why Do Some Patients Develop Neuropathic Pain and Others Not?, in Pain in Peripheral Nerve Diseases, , C. Sommer, Editor. 2001, Karger: Basel. pp. 168–170.Google Scholar
Sorensen, J., , A. Bengtsson, , E. Backman, , K. G. Henrikson, and , M. Bengtsson, Pain Analysis in Patients with Fibromyalgia: Effects of Intravenous Morphine, Lidocaine and Ketamine. J. Rheumatology, 1995. 24: pp. 360–365.Google ScholarPubMed
Sorensen, J., , A. Bengtsson, , J. Ahlner, and , E. Al, Fibromyalgia – Are There Different Mechanisms in the Processing of Pain? A Double Blind Crossover Comparison of Analgesic Drugs. J. Rheumatology, 1997. 24: pp. 1615–1621.Google Scholar
Stubhaug, A., , H. Breivik, , P. K. Eide, , M. Kreunen, and , A. Foss, Mapping of Punctuate Hyperalgesia around a Surgical Incision Demonstrates That Ketamine Is a Powerful Suppressor of Central Sensitization to Pain Following Surgery. Acta Anaesthesiologica Scand., 1997. 41(9): pp. 1124–1132.CrossRefGoogle ScholarPubMed
Sugar, O., Victor Horsley, John Marshall, Nerve Stretching, and the Nervi Nervorum. Surg. Neurol., 1990. 34(3): pp. 184–7.CrossRefGoogle Scholar
Sugimoto, T., G. J. Bennett, and K. C. Kajander, Transsynaptic Degeneration in the Superficial Dorsal Horn after Sciatic Nerve Injury: Effects of Chronic Constriction Injury, Transection, and Strychnine. 42, 1990: pp. 205–213.
Sweet, W. H., Deafferentation Pain after Posterior Rhizotomy, Trauma to a Limb, and Herpes Zoster. Neurosurgery, 1984. 15(6): pp. 928–32.Google ScholarPubMed
Tanimoto, T., , M. Takeda, and , S. S. Matsumoto, Suppressive Effect of Vagal Afferents on Cervical Dorsal Horn Neurons Responding to Tooth Pulp Electrical Stimulation in the Rat. Experimental Brain Research, 2002. 145(4): pp. 468–79.CrossRefGoogle ScholarPubMed
Tasker, R. R., Reflex Sympathetic Dystrophy – Neurosurgical Approaches, in Reflex Sympathetic Dystrophy, , M. Stanton-Hicks, , W. Jänig, and , R. A. Roas, Editors. 1990, Kluwer Academic: MA. pp. 125–34.Google Scholar
Thompson, S. W. N., , A. E. King, and , C. J. Woolf, Activity-Dependent Changes in Rat Ventral Horn Neurons in Vitro: Summation of Prolonged Afferent Evoked Post-Synaptic Depolarization Produce a D-Apv Sensitive Wind-Up. Eur. J. Neurosci., 1990. 2: pp. 638–649.CrossRefGoogle Scholar
Tohda, C., , T. Yamaguchi, and , Y. Kuraishi, Intracisternal Injection of Opioids Induces Itch – Associated Response through Mμ-Opioid Receptors in Mice. Jap. J.Pharmacol., 1997.CrossRefGoogle Scholar
Torebjoerk, H. E. and , J. L. Ochoa, Pain and Itch from C-Fiber Stimulation. Society for Neuroscience Abstracts, 1981. 7: pp. 228.Google Scholar
Tran, T. D., , K. Inui, , M. Hoshiyama, , K. Lam, and , R. Kakigi, Conduction Velocity of the Spinothalamic Tract Following Co2 Laser Stimulation of C-Fibers in Humans. Pain, 2002. 95: pp. 125–131.CrossRefGoogle ScholarPubMed
Travell, J., , S. Rinzler, and , M. Herman, Pain and Disability of the Shoulder and Arm, Treatment with Infiltration with Procaine Hydrochloride. JAMA, 1942. 120(6): pp. 417–22.CrossRefGoogle Scholar
Travell, J. and , D. G. Simons, Myofascial Pain and Dysfunction, the Trigger Point Manual. 1983, Williams and Wilkins: New York.Google Scholar
Urban, M. O. and , G. F. Gebhart, Supraspinal Contribution to Hyperalgesia. Proc. Nat. Acad. Sci, 1999. 96: pp. 7687–7692.CrossRefGoogle ScholarPubMed
Valbo, A. B., , K. E. Hagbarth, , H. E. Torebjoerk, and , B. G. Wallin, Somatosensory Proprioceptive, and Sympathetic Activity in Human Peripheral Nerves. Physiol. Rev., 1979. 59: pp. 919–957.CrossRefGoogle Scholar
Vandenheede, M. and , J. Schoenen, Central Mechanisms in Tension-Type Headaches. Curr. Pain Headache Rep., 2002. 6(5): pp. 392 400.CrossRefGoogle ScholarPubMed
Wall, P. D., The Presence of Ineffective Synapses and Circumstances Which Unmask Them. Phil. Trans. Royal Soc. (Lond.), 1977. 278: pp. 361–372.CrossRefGoogle Scholar
Wall, P. D. and , M. Devor, Sensory Afferent Impulses Originate from Dorsal Root Ganglia as Well as from Periphery in Normal and Nerve Injured Rats. Pain, 1983. 17: pp. 321–339.CrossRefGoogle ScholarPubMed
Wall, P. D. and , R. Melzack, Textbook of Pain, Fourth Ed. 4th ed. 1999, Churchill-Livingstone: Edinburgh.Google Scholar
Wallengren, J., , E. Tegner, and , F. Sundler, Cutaneous Sensory Fibers Are Decreased in Number in Peripheral and Central Nerve Damage. J. Am. Acad. Dermatol., 2002. 46(2): pp. 215–7.CrossRefGoogle ScholarPubMed
Walsh, E. G., Muscles, Masses and Motion: The Physiology of Normality, Hypotonicity, Spasticity and Rigidity. 1992, Blackwell: Oxford.CrossRef
Weber, H., The Natural History of Disc Herniation and the Influence of Intervention. Spine, 1994. 19: pp. 2234–2238.CrossRefGoogle ScholarPubMed
Weltz, C. R., , S. M. Klein, , J. E. Arbo, and , R. A. Greengrass, Paravertebral Block Anesthesia for Inguinal Hernia Repair. World Journal of Surgery, 2003. 27(4): pp. 425–9.CrossRefGoogle ScholarPubMed
Whipple, B., , C. A. Gerdes, and , B. R. Komisaruk, Sexual Response to Self-Stimulation in Women with Complete Spinal Cord Injury. J. Sex. Res., 1996. 33: pp. 231–240.CrossRefGoogle Scholar
Whipple, B. and , B. R. Komisaruk, Brain (Pet) Responses to Vaginal-Cervical Self-Stimulation in Women with Complete Spinal Cord Injury: Preliminary Findings. J. Sex & Marital Therapy, 2002. 28(1): pp. 79–86.CrossRefGoogle ScholarPubMed
Willer, J. C., Relieving Effect of Tens on Painful Muscle Contraction Produced by an Impairment of Reciprocal Innervation: An Electrophysiological Analysis. Pain, 1988. 32: pp. 271–274.CrossRefGoogle ScholarPubMed
Willis, W. D., From Nociceptor to Cortical Activity, in Pain and the Brain, , B. Bromm and , J. E. Desmedt Editors. 1995, Raven Press: New York. pp. 1–19.Google Scholar
Woolf, C. J., Evidence of a Central Component of Postinjury Pain Hypersensitivity. Nature, 1983. 308: pp. 686–688.CrossRefGoogle Scholar
Woolf, C. J. and , S. W. N. Thompson, The Induction and Maintenance of Central Sensitization Is Dependent on N-Methyl-D-Aspartic Acid Receptor Activation: Implications for the Treatment of Post-Injury Pain Hypersensitivity States. Pain, 1991. 44: pp. 293–299.CrossRefGoogle ScholarPubMed
Woolf, C. J., , P. Shortland, and , R. E. Cogershall, Peripheral Nerve Injury Triggers Central Sprouting of Myelinated Afferents. Nature, 1992. 355: pp. 75–78.CrossRefGoogle ScholarPubMed
Woolf, C. J. and , R. J. Mannion, Neuropathic Pain: Aetiology, Symptoms, Mechanisms, and Managements. The Lancet, 1999. 353: pp. 1959–1964.CrossRefGoogle Scholar
Woolf, C. J. and , M. W. Salter, Neural Plasticity: Increasing the Gain in Pain. Science, 2000. 288: pp. 1765–1768.CrossRefGoogle ScholarPubMed
Yakhnitsa, V., , B. Linderoth, and , B. A. Meyerson, Spinal Cord Stimulation Attenuates Dorsal Horn Hyperexcitability in a Rat Model of Mononeuropathy. Pain, 1999. 79: pp. 223–233.CrossRefGoogle Scholar
Yaksh, T. L., Preclinical Models of Nociception, in Anesthesia: Biological Functions, , T. L. Yaksh, et al., Editors. 1997, Lippincott-Raven Publishers: Philadelphia.Google Scholar
Yaksh, T. L., Central Pharmacology of Nociceptive Transmission, in Textbook of Pain, , P. D. Wall and , R. Melzack, Editors. 1999, Churchill Livingstone: Edinburgh. pp. 253–308.Google Scholar
Yosipovitch, G., , C. Szolar, , X. Y. Hui, and , H. Maibach, Effect of Topically Applied Menthol on Thermal, Pain and Itch Sensations and Biophysical Properties of the Skin. Arch. Arch. Dermatol. Res., 1996. 288: pp. 245–8.CrossRefGoogle Scholar
Young, R. F., , R. Kroening, , W. Fulton, , R. A. Feldman, and , I. Chambi, Electrical Stimulation of the Brain in Treatment of Chronic Pain. Experience over 5 Years. J. Neurosurg., 1985. 62: pp. 389–396.CrossRefGoogle ScholarPubMed
Young, R. F., , V. Tronnier, and , P. C. Rinaldi, Chronic Stimulation of the Kolliker-Fuse Nucleus Region for Relief of Intractable Pain in Humans. J. Neurosurg, 1992. 76: pp. 979–985.CrossRefGoogle ScholarPubMed
Young, R. F., , D. S. Jacques, , R. W. Rand, , B. C. Copcutt, , S. S. Vermeulen, and , A. E. Posewitz, Technique of Stereotactic Medical Thalamotomy with the Leksell Gamma Knife for Treatment of Chronic Pain. Neurol. Res., 1995. 17(1): pp. 59–65.CrossRefGoogle ScholarPubMed
Young, R. F., Deep Brain Stimulation for Failed Back Surgery Syndrome, in Textbook of Stereotactic Surgery, , P. L. Gildenberg and , R. R. Tasker, Editors. 1998, McGraw Hill: New York. pp. 1621.Google Scholar
Zakrzewska-Pniewska, B. and , M. Jedras, Is Pruritus in Chronic Uremic Patients Related to Peripheral Somatic and Autonomic Neuropathy? Study by R-R Interval Variation Test (RRIV) and by Sympathetic Skin Response (SSR). Neurophysiol Clinique, 2001. 311(3): pp. 181–93.CrossRefGoogle Scholar
Zimmermann, M., Physiological Mechanisms of Pain in Muscloskeletal System, in Muscle Spasms and Pain, , M. Emre and , H. Mathies, Editors. 1988, Parthenon Publishing: Carnforth. pp. 7–17.Google Scholar
Zirh, A., , S. G. Reich, , P. M. Dougherty, and , F. A. Lenz, Stereotactic Thalamotomy in the Treatment of Essential Tremor of the Upper Extremity: Reassessment Including a Blinded Measure of Outcome. J. Neurol. Neurosurg. Psych., 1999. 66(6): pp. 772–5.CrossRefGoogle Scholar
Zochodne, D. W., Epineurial Peptides: A Role in Neuropathic Pain?Canadian. J. Neurol. Sci., 1993. 20(1): pp. 69–72.CrossRefGoogle ScholarPubMed

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  • Pain
  • Aage R. Møller, University of Texas, Dallas
  • Book: Neural Plasticity and Disorders of the Nervous System
  • Online publication: 08 February 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511616228.005
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  • Pain
  • Aage R. Møller, University of Texas, Dallas
  • Book: Neural Plasticity and Disorders of the Nervous System
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  • Chapter DOI: https://doi.org/10.1017/CBO9780511616228.005
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  • Pain
  • Aage R. Møller, University of Texas, Dallas
  • Book: Neural Plasticity and Disorders of the Nervous System
  • Online publication: 08 February 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511616228.005
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