Skip to main content Accessibility help
×
Hostname: page-component-76fb5796d-vvkck Total loading time: 0 Render date: 2024-04-29T23:17:03.064Z Has data issue: false hasContentIssue false

19 - Dermatoses

from Section 5 - Other disorders

Published online by Cambridge University Press:  19 October 2009

Robert S. F. McKay
Affiliation:
Clinical Professor and Chair, Department of Anesthesiology, University of Kansas, School of Medicine – Wichita, Wichita, KS, USA
John E. Schlicher
Affiliation:
Private Practice, Dermatologist, Beatrice Keller Clinic, Sun City West, AZ, USA
David R. Gambling
Affiliation:
University of California, San Diego
M. Joanne Douglas
Affiliation:
University of British Columbia, Vancouver
Robert S. F. McKay
Affiliation:
University of Kansas
Get access

Summary

Introduction

The hormonal environment during pregnancy leads to significant changes in the integumentary system of virtually all pregnant women. In a few, skin changes may become pathologic. Likewise, women with nonpregnancy-related skin disorders may become pregnant, and the pregnancy may affect the course of the disease or, alternatively, the skin disorder may adversely affect the mother or the fetus. This chapter will focus on (1) normal changes of the skin during pregnancy, (2) pathologic skin disorders that occur primarily in pregnant women, (3) other dermatologic disorders with significant effects on the mother and/or fetus, and (4) the anesthetic considerations for women with these dermatologic disorders. Certain diseases that affect the skin in pregnancy, such as autoimmune diseases, are discussed in detail in other chapters. These diseases may be mentioned only in passing in the current chapter, even though the degree of skin involvement may be substantial.

Functions of the skin

The integumentary system comprises approximately 16% of body weight. It is a system containing multiple tissues including skin itself (epidermis, dermis, and hypodermis), glands (sudoriferous and sebaceous), hair, nails, nervous tissue, blood vessels, and even muscle (piloerector muscles). Although considered a single organ, the skin serves multiple discrete and interactive functions. As a barrier, it protects the body from physical agents, mechanical injury, dehydration, and ultraviolet radiation. The proper balance of collagen and elastic fibers gives skin flexibility while preventing overstretching. The skin's secretory glands, fat, and vascular system help regulate body temperature.

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Birnbach, D. J., Stein, D. J., Murray, O.et al. Povidone iodine and skin disinfection before initiation of epidural anesthesia. Anesthesiology 1998; 88: 668–72.Google Scholar
Messager, S., Goddard, P. A., Dettmar, P. W. & Maillard, J. Y.Comparison of two in vivo and two ex vivo tests to assess the antibacterial activity of several antiseptics. J. Hosp. Infect. 2004; 58: 115–21.Google Scholar
Douglas, M. J. & Swenerton, J. E.Epidural anesthesia in three parturients with lumbar tattoos: a review of possible implications. Can. J. Anaesth. 2002; 49: 1057–60.Google Scholar
Mortimer, N. J., Chave, T. A. & Johnston, G. A.Red tattoo reactions. Clin. Exp. Dermatol. 2003; 28: 508–10.Google Scholar
Camann, W. R. Tattoos and spinal/epidural anesthesia. www.storknet.com/cubbies/childbirth/exwc3.htm. Accessed July 31, 2005.
Shatz, B. A., Weinstock, L. B., Swanson, P. E. & Thyssen, EP. Long-term safety of India ink tattoos in the colon. Gastrointest. Endosc. 1997; 45: 153–6.Google Scholar
Garahan, M. B. & Licata, A. Dermatoses. In Gambling, D. R. & Douglas, M. J. (eds.), Obstetric Anesthesia and Uncommon Disorders, 1st edn. Philadelphia: W. B. Saunders, 1998, p. 354.
Schmultz, J. L.Specific dermatoses of pregnancy. Presse Med. 2003; 32: 1813–17.Google Scholar
Walters, J. & Clark, D. C.Photo quiz: pruritic rash during pregnancy. Am. Fam. Physician 2005; 71: 1380.Google Scholar
Thappa, D. M. & Shanmugam, S.Pruritus gravidarum. Indian J. Dermatol. 1999; 44: 1–5.Google Scholar
Buccolo, L. S. & Viera, A. J.Pruritic urticarial papules and plaques of pregnancy presenting in the postpartum period: a case report. J. Reprod. Med. 2005; 50: 61–3.Google Scholar
Lawley, T. J., Hertz, K. C., Wade, T. R.et al. Pruritic urticarial papules and plaques of pregnancy. J.A.M.A. 1979; 241: 1696–9.Google Scholar
Goh, C. L.Clinician's photo guide to recognizing and treating skin diseases in women: Part 2. Pregnancy-related dermatoses. Medscape Womens' Health 1997; 2: 5.Google Scholar
Elling, S. V., McKenna, P. & Powell, F. C.Pruritic urticarial papules and plaques of pregnancy in twin and triplet pregnancies. J. Eur. Acad. Dermatol. Venereol. 2000; 14: 378–81.Google Scholar
Aronson, I. K., Bond, S., Fiedler, V. C.et al. Pruritic urticarial papules and plaques of pregnancy: clinical and immunopathologic observations in 57 patients. J. Am. Acad. Dermatol. 1998; 39: 933–9.Google Scholar
Weisshaar, E., Witteler, R., Diepgen, T. L.et al. Pruritus in pregnancy. A frequent diagnostic and therapeutic challenge. Hautarzt. 2005; 56: 48–57.Google Scholar
High, W. A., Hoang, M. P. & Miller, M. D.Pruritic urticarial papules and plaques of pregnancy with unusual and extensive palmoplantar involvement. Obstet. Gynecol. 2005; 105: 1261–4.Google Scholar
Landon, M. B. Dermatologic disorders. In Gabbe, S. G., Niebyl, J. R. & Simpson, J. L. (eds.), Obstetrics, 2nd edn. New York: Churchill Livingstone, 1991, p. 1218.
Normand, F., Armingaud, P. & Esteve, E.Dyshidrosis and acral purpura during polymorphic dermatitis in pregnancy: 2 cases. Ann. Dermatol. Venereol. 2001; 128: 531–3.Google Scholar
Rapini, R. P. & Jordan, R. E. The skin and pregnancy. In Creasy, R. K. & Resnick, R. (eds.), Maternal-Fetal Medicine, 2nd edn. Philadelphia: W. B. Saunders, 1989, p. 1114.
Mullally, B. A. & Hansen, W. F.Intrahepatic cholestasis of pregnancy: review of the literature. Obstet. Gynecol. Surv. 2002; 57: 47–52.Google Scholar
Roncaglia, N., Arreghini, A., Locatelli, A.et al. Obstetric cholestasis: outcome with active management. Eur. J. Obstet. Gynecol. Reprod. Biol. 2002; 100: 167–70.Google Scholar
Devree, J., Jacquemin, E. & Sturm, E.et al. Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis. Proc. Nat. Acad. Sci. USA 1998; 95: 282–7.Google Scholar
Girardin, Saint-Marc M. F.Hepatic complications of oral contraceptives. Contracept. Fertil. Sex. 1984; 12: 13–16.Google Scholar
Paus, T. C., Schneider, G., Vondel, P.et al. Diagnosis and therapy of intrahepatic cholestasis of pregnancy. Z. Gastroenterol. 2004; 42: 623–8.Google Scholar
Greaves, M. W. Pathophysiology and clinical aspects of pruritus. In Fitzpatrick, T. B., Eisen, A. Z., Wolff, K.et al. (eds.), Dermatology in General Medicine, 4th edn, Vol. I. New York: McGraw-Hill, 1993, p. 416.
Pauli-Magnus, C. & Meier, P. J.Hepatocellular transporters and cholestasis. J. Clin. Gastroenterol. 2005; 39: S103–S110.Google Scholar
Winton, G. B. & Lewis, C. W.Dermatoses of pregnancy. J. Am. Acad. Dermatol. 1982; 6: 977–98.Google Scholar
Dann, A. T., Kenyon, A. P., Seed, P. T.et al. Glutathione S-transferase and liver function in intrahepatic cholestasis of pregnancy and pruritus gravidarum. Hepatology 2004; 40: 1406–14.Google Scholar
Fisk, N. M. & Storey, G. N.Fetal outcome in obstetric cholestasis. Br. J. Obstet. Gynaecol. 1988; 95: 1137–43.Google Scholar
Kondrackiene, J., Beuers, U. & Kupcinskas, L.Efficacy and safety of ursodeoxycholic acid versus cholestyramine in intrahepatic cholestasis of pregnancy. Gastroenterology 2005; 129: 894–901.Google Scholar
Riely, C. A. & Bacq, Y.Intrahepatic cholestasis of pregnancy. Clin. Liver Dis. 2004; 8: 167–76.Google Scholar
Davies, M. H., Silva, da R. C., Jones, S. R.et al. Fetal mortality associated with cholestasis of pregnancy and the potential benefit of therapy with ursodeoxycholic acid. Gut 1995; 37: 580–4.Google Scholar
Kowdley, K. V.Lipids and lipid-activated vitamins in chronic cholestatic diseases. Clin. Liver Dis. 1998; 2: 373–89.Google Scholar
Yarnell, R. W. & D'Alton, M. E.Epidural hematoma complicating cholestasis of pregnancy. Curr. Opin. Obstet. Gynecol. 1996; 8: 239–42.Google Scholar
Schumann, R. & Hudcova, J.Cholestasis of pregnancy, pruritus and 5-hydroxytryptamine 3 receptor antagonists. Acta Obstet. Gynecol. Scand. 2004; 83: 861–2.Google Scholar
Milton, J. L.The Pathology and Treatment of Diseases of the Skin. London: Robert Hardwick, 1872, p. 201.
Amato, L., Coronella, G., Berti, S.et al. Successful treatment with doxycycline and nicotinamide of two cases of persistent pemphigoid gestationis. J. Dermatolog. Treat. 2002; 13: 143–6.Google Scholar
Hacker-Foegen, M. K., Zillikens, D., Giudice, G. J. & Lin, M. S. Tcell receptor gene usage of BP180-specific T lymphocytes from patients with bullous pemphigoid and pemphigoid gestationis. Clin. Immunol. 2004; 113: 179–86.Google Scholar
Borthwick, G. M., Holmes, R. C. & Stirrat, G. M.Abnormal expression of class II MHC antigens in placentae from patients with pemphigoid gestationis: analysis of class II MHC subregion product expression. Placenta 1988; 9: 81–94.Google Scholar
Shornick, J. K.Herpes gestationis. Dermatol. Clin. 1993; 11: 527–33.Google Scholar
Shornick, J. K., Meek, T. J., Nesbitt, L. T. Jr. & Gilliam, J. N.Herpes gestationis in blacks. Arch. Dermatol. 1984; 120: 511–13.Google Scholar
Shornick, J. K., Stastny, P. & Gilliam, J. N.Paternal histocompatibility (HLA) antigens and maternal anti-HLA antibodies in herpes gestationis. J. Invest. Dermatol. 1983; 81: 407–9.Google Scholar
Shornick, J. K. & Black, M. M.Secondary autoimmune diseases in herpes gestationis (pemphigoid gestationis). J. Am. Acad. Dermatol. 1992; 26: 563–6.Google Scholar
Kromminga, A., Sitaru, C., Meyer, J.et al. Cicatricial pemphigoid differs from bullous pemphigoid and pemphigoid gestationis regarding the fine specificity of autoantibodies to the BP180 NC16 A domain. J. Dermatol. Sci. 2002; 28: 68–75.Google Scholar
Zillikens, D.BP180 as the common autoantigen in blistering diseases with different clinical phenotypes. Keio J. Med. 2002; 51: 21–8.Google Scholar
Wilson, B. D., Beutner, E. H., Kumar, V.et al. Linear IgA bullous dermatosis. An immunologically defined disease. Int. J. Dermatol. 1985; 24: 569–74.Google Scholar
Carrozzo, M., Broccoletti, R., Carbone, M.et al. Pemphigoid of the mucous membranes. The clinical, histopathological and immunological aspects and current therapeutic concepts. Minerva Stomatol. 1996; 45: 455–63.Google Scholar
Harris-Stith, R., Erickson, Q. L., Elston, D. M. & David-Bajar, K.Bullous eruption: a manifestation of lupus erythematosus. Cutis 2003; 72: 31–7.Google Scholar
Buscher, U., Wessel, J., Anton-Lamprecht, I. & Dudenhausen, J. W.Pregnancy and delivery in a patient with mutilating dystrophic epidermolysis bullosa (Hallopeau-Siemens type). Obstet. Gynecol. 1997; 89: 817–20.Google Scholar
Mola, Loret J. R., Muise, K. L. & Duchon, M. A.Porphyria cutanea tarda and pregnancy. Obstet. Gynecol. Surv. 1996; 51: 493–7.Google Scholar
Claessens, N., Delbeke, L., Lambert, J.et al. Toxic epidermal necrolysis associated with treatment for preterm labor. Dermatology 1998; 196: 461–2.Google Scholar
Leung, A.Toxic epidermal necrolysis associated with maternal use of heparin. J.A.M.A. 1985; 253: 201.Google Scholar
Lawley, T. J., Stingl, G. & Katz, I.Fetal and maternal risk factors in herpes gestationis. Arch. Dermatol. 1978; 114: 552–5.Google Scholar
Holmes, R. C. & Black, M. M.The fetal prognosis in pemphigoid gestationis (herpes gestationis). Br. J. Dermatol. 1984; 110: 67–72.Google Scholar
Shornick, J. K. & Black, M. M.Fetal risks in herpes gestationis. J. Am. Acad. Dermatol. 1992; 26: 63–8.Google Scholar
Faiz, S. A., Nainar, S. I. & Addar, M. H.Herpes gestationis. Saudi Med. J. 2004; 25: 792–4.Google Scholar
Erickson, N. I. & Ellis, R. L.Images in clinical medicine. Neonatal rash due to herpes gestationis. N. Engl. J. Med. 2002; 347: 660.Google Scholar
Chen, S. H., Chopra, K., Evans, T. Y.et al. Herpes gestationis in a mother and child. J. Am. Acad. Dermatol. 1999; 40: 847–9.Google Scholar
Berthier, M., Nasimi, A., Boussemart, T.et al. Neurologic manifestations in a child of a mother with gestational herpes. Arch. Pediatr. 1996; 3: 460–2.Google Scholar
Szeremeta, W. & Dohar, J. E.Dapsone-induced methemoglobinemia: an anesthetic risk. Int. J. Pediatr. Otorhinolaryngol. 1995; 33: 75–80.Google Scholar
Kabra, N. S., Nanavati, R. N. & Srinivasan, G.Neonatal methemoglobinemia due to transplacental transfer of dapsone. Indian Pediatr. 1998; 35: 553–5.Google Scholar
Golusin, Z., Poljacki, M., Preveden, R.et al. What do we know today about diaminodiphenylsulfone?Med. Pregl. 2000; 53: 369–72.Google Scholar
Schmutz, J. L.Specific dermatoses of pregnancy. Presse Med. 2003; 32: 1813–17.Google Scholar
Erbagci, Z. & Erkilic, S.A case of recurrent impetigo herpetiformis with a positive family history. Int. J. Clin. Pract. 2000; 54: 619–20.Google Scholar
Stewart, A. F., Battaglini-Sabetta, J. & Millstone, L.Hypocalcemia-induced pustular psoriasis of von Zumbusch. New experience with an old syndrome. Ann. Intern. Med. 1984; 100: 677–80.Google Scholar
Gollnick, H. P.Oral retinoids – efficacy and toxicity in psoriasis. Br. J. Dermatol. 1996; 135: 6–17.Google Scholar
Roizen, M. F. Diseases of the endocrine system. In Katz, J., Benumof, J. L. & Kadis, L. B. (eds.), Anesthesia and Uncommon Diseases, 3rd edn. Philadelphia: W.B. Saunders, 1990, p. 254.
Yeowell, H. N. & Pinnell, S. R.The Ehlers-Danlos syndromes. Semin. Dermatol. 1993; 12: 229–40.Google Scholar
Kuczkowski, K. M. & Benumof, J. L.Cesarean section and Ehlers-Danlos syndrome: choice of anesthesia. Int. J. Obstet. Anesth. 2002; 11: 222–4.Google Scholar
Goldstein, M. & Miller, R.Anesthesia for cesarean delivery in a patient with Ehlers-Danlos syndrome type II. Reg. Anesth. 1997; 22: 280–3.Google Scholar
Vos, M., Nuytinck, L., Verellen, C. & Paepe, A.Preterm premature rupture of membranes in a patient with the hypermobility type of the Ehlers-Danlos syndrome. A case report. Fetal Diagn. Ther. 1999; 14: 244–7.Google Scholar
Klipple, G. L. & Riordan, K. K.Rare inflammatory and hereditary connective tissue diseases. Rheum. Dis. Clin. North Am. 1989; 15: 383–98.Google Scholar
Lurie, S., Manor, M. & Hagay, Z. J.The threat of type IV Ehlers-Danlos syndrome on maternal well-being during pregnancy: early delivery may make the difference. J. Obstet. Gynaecol. 1998; 18: 245–8.Google Scholar
Dolan, P., Sisko, F. & Riley, E.Anesthetic considerations for Ehlers-Danlos syndrome. Anesthesiology 1980; 52: 266–9.Google Scholar
Anstey, A., Mayne, K., Winter, M.et al. Platelet and coagulation studies in Ehlers-Danlos syndrome. Br. J. Dermatol. 1991; 125: 155–63.Google Scholar
Safdar, Z., O'Sullivan, M. & Shapiro, J. M.Emergent bullectomy for acute respiratory failure in Ehlers-Danlos syndrome. J. Intensive Care Med. 2004; 19: 349–51.Google Scholar
Halko, G. J., Cobb, R. & Abeles, M.Patients with type IV Ehlers-Danlos syndrome may be predisposed to atlantoaxial subluxation. J. Rheumatol. 1995; 22: 2152–5.Google Scholar
Dill-Russell, P. & Jones, L. S.Anaesthesia for caesarean section in a patient with Ehlers-Danlos syndrome and mitral valve prolapse. Int. J. Obstet. Anesth. 2001; 10: 192–7.Google Scholar
Campbell, N. & Rosaeg, O. P.Anesthetic management of a parturient with Ehlers Danlos syndrome type IV. Can. J. Anaesth. 2002; 49: 493–6.Google Scholar
Brighouse, D. & Guard, B.Anaesthesia for caesarean section in a patient with Ehlers-Danlos syndrome type IV. Br. J. Anaesth. 1992; 69: 517–19.Google Scholar
Abouleish, E.Obstetric anaesthesia and Ehlers-Danlos syndrome. Br. J. Anaesth. 1980; 52: 1283–6.Google Scholar
Smith, F.The molecular genetics of keratin disorders. Am. J. Clin. Dermatol. 2003; 4: 347–64.Google Scholar
Pfendner, E. G., Nakano, A., Pulkkinen, L.et al. Prenatal diagnosis for epidermolysis bullosa: a study of 144 consecutive pregnancies at risk. Prenat. Diagn. 2003; 23: 447–56.Google Scholar
Eady, R. A.Epidermolysis bullosa: scientific advances and therapeutic challenges. J. Dermatol. 2001; 28: 638–40.Google Scholar
Benavente, M. A. & Sanchez-Guijo, J. J.Combined anaesthesia in a young patient with dystrophic epidermolysis bullosa. Paediatr. Anaesth. 2003; 13: 274.Google Scholar
Herod, J., Denyer, J., Goldman, A. & Howard, R.Epidermolysis bullosa in children: pathophysiology, anaesthesia and pain management. Paediatr. Anaesth. 2002; 12: 388–97.Google Scholar
Diwan, R., Vas, L., Shah, T.et al. Continuous axillary block for upper limb surgery in a patient with epidermolysis bullosa simplex. Paediatr. Anaesth. 2001; 11: 603–6.Google Scholar
Iohom, G. & Lyons, B.Anaesthesia for children with epidermolysis bullosa: a review of 20 years' experience. Eur. J. Anaesthesiol. 2001; 18: 745–54.Google Scholar
Scherhag, A. & Dick, W.Special aspects of anesthesia in patients with epidermolysis bullosa based on a case example. Anaesthesiol. Reanim. 1998; 23: 129–33.Google Scholar
Lin, A. N., Lateef, F., Kelly, R.et al. Anesthetic management in epidermolysis bullosa: review of 129 anesthetic episodes in 32 patients. J. Am. Acad. Dermatol. 1994; 30: 412–16.Google Scholar
Spielman, F. J. & Mann, E. S.Subarachnoid and epidural anaesthesia for patients with epidermolysis bullosa. Can. Anaesth. Soc. J. 1984; 31: 549–51.Google Scholar
Boughton, R., Crawford, M. R. & Vonwiller, J. B.Epidermolysis bullosa – a review of 15 years' experience, including experience with combined general and regional anaesthetic techniques. Anaesth. Intensive Care 1988; 16: 260–4.Google Scholar
Ohara, T., Fujimoto, K., Okutsu, Y.et al. Intraoperative indirect monitoring of electrocardiogram. Masui 1999; 48: 1347–53.Google Scholar
Farthing, B., Bagan, J. V. & Scully, C.Mucosal disease series. Number IV. Erythema multiforme. Oral. Dis. 2005; 11: 261–7.Google Scholar
Bastuji-Garin, S., Rzany, B., Stern, R. S.et al. Clinical classification of cases of toxic epidermal necrolysis, Stevens-Johnson syndrome, and erythema multiforme. Arch. Dermatol. 1993; 129: 92–6.Google Scholar
Sehgal, V. N. & Srivastava, G.Toxic epidermal necrolysis (TEN) Lyell's syndrome. J. Dermatolog. Treat. 2005; 16: 278–86.Google Scholar
Roujeau, J. C.Stevens-Johnson syndrome and toxic epidermal necrolysis are severity variants of the same disease which differs from erythema multiforme. J. Dermatol. 1997; 24: 726–9.Google Scholar
Nekhlyudov, L., Gradzka, M., Conti-Kelly, A. M. & Greco, T. P.Erythema nodosum associated with antiphospholipid antibodies: a report of three cases. Lupus 2000; 9: 641–5.Google Scholar
Mert, A., Ozaras, R., Tabak, F.et al. Erythema nodosum: an experience of 10 years. Scand. J. Infect. Dis. 2004; 36: 424–7.Google Scholar
Tay, Y. K.Erythema nodosum in Singapore. Clin. Exp. Dermatol. 2000; 25: 377–80.Google Scholar
Requena, L. & Requena, C.Erythema nodosum. Dermatol. Online J. 2002; 8: 4.Google Scholar
Ytting, H., Vind, I., Bang, D. & Munkholm, P.Sweet's syndrome – an extraintestinal manifestation in inflammatory bowel disease. Digestion 2005; 72: 195–200.Google Scholar
Cohen, P. R.Pregnancy-associated Sweet's syndrome: world literature review. Obstet. Gynecol. Surv. 1993; 48: 584–7.Google Scholar
Silverman, M. A., Datner, E. M. & Jolly, B. T.A case presentation of Sweet's syndrome and discussion of life-threatening dermatoses. Am. J. Emerg. Med. 1996; 14: 165–9.Google Scholar
Matoses, M. S., Alcala, E. & Laguarda, M.Subarachnoid anesthesia for cesarean section of a patient with Sweet's syndrome related to pregnancy. Rev. Esp. Anestesiol. Reanim. 2004; 51: 111–12.Google Scholar
Smith, L. H., Danielsen, B., Allen, M. E. & Cress, R.Cancer associated with obstetric delivery: results of linkage with the California cancer registry. Am. J. Obstet. Gynecol. 2003; 189: 1128–35.Google Scholar
Uhoda, I., Pierard-Franchimont, C., Arrese, J. E.et al. How to investigate. A darkened skin lesion during pregnancy. A difficult task for the clinician. Rev. Med. Liege 2003; 58: 766–9.Google Scholar
O'Meara, A. T., Cress, R., Xing, G.et al. Malignant melanoma in pregnancy. A population-based evaluation. Cancer 2005; 103: 1217–26.Google Scholar
Lens, M. B., Rosdahl, I., Ahlbom, A.et al. Effect of pregnancy on survival in women with cutaneous malignant melanoma. J. Clin. Oncol. 2004; 22: 4369–75.Google Scholar
Naldi, L., Imberti, Lorenzo G., Parazzini, F.et al. Pigmentary traits, modalities of sun reaction, history of sunburns, and melanocytic nevi as risk factors for cutaneous malignant melanoma in the Italian population: results of a collaborative case-control study. Cancer 2000; 88: 2703–10.Google Scholar
Alexander, A., Samlowski, W. E., Grossman, D.et al. Metastatic melanoma in pregnancy: risk of transplacental metastases in the infant. J. Clin. Oncol. 2003; 21: 2179–86.Google Scholar
Heesen, M. & Rossaint, R.Anaesthesiological considerations in patients with Sneddon's syndrome. Paediatr. Anaesth. 2000; 10: 678–80.Google Scholar
Toubi, E., Krause, I., Fraser, A.et al. Livedo reticularis is a marker for predicting multi-system thrombosis in antiphospholipid syndrome. Clin. Exp. Rheumatol. 2005; 23: 499–504.Google Scholar
Frances, C., Papo, T., Wechsler, B.et al. Sneedon syndrome with or without antiphosholipid antibodies. A comparative study in 46 patients. Medicine 1999; 78: 209–19.Google Scholar
www.nfinc.org. Site accessed July 31, 2005.
The Elephant Man's Bones Reveal Mystery. http://rarediseases.about.com/cs/proteussyndrome/a/031301.htm. Accessed July 31, 2005.
Spits, C., Rycke, M., Ranst, N.et al. Preimplantation genetic diagnosis for neurofibromatosis type 1. Mol. Hum. Reprod. 2005; 11: 381–7. Epub 2005 Apr 15.Google Scholar
Agarwal, U., Dahiya, P. & Sangwan, K.Recent onset neurofibromatosis complicating eclampsia with maternal death: a case report. Arch. Gynecol. Obstet. 2003; 268: 241–2.Google Scholar
Posma, E., Aalbers, R., Kurniawan, Y. S.et al. Neurofibromatosis type I and pregnancy: a fatal attraction? Development of malignant schwannoma during pregnancy in a patient with neurofibromatosis type I. B.J.O.G. 2003; 110: 530–2.Google Scholar
Kusaba, T., Oguni, A., Narumiya, H.et al. Intravascular ultrasound imaging of the renal artery in patients with renovascular hypertension caused by neurofibromatosis 1. Nippon Jinzo Gakkai Shi 2003; 45: 32–6.Google Scholar
Tidwell, C. & Copas, P.Brachial artery rupture complicating a pregnancy with neurofibromatosis: a case report. Am. J. Obstet. Gynecol. 1998; 179: 832–4.Google Scholar
Serleth, H. J., Cogbill, T. H. & Gundersen, S. B., 3rd. Ruptured pancreaticoduodenal artery aneurysms and pheochromocytoma in a pregnant patient with neurofibromatosis. Surgery 1998; 124: 100–2.Google Scholar
Segal, D., Holcberg, G., Sapir, O.et al. Neurofibromatosis in pregnancy. Maternal and perinatal outcome. Eur. J. Obstet. Gynecol. Reprod. Biol. 1999; 84: 59–61.Google Scholar
Tubbs, R. S., Rutledge, S. L., Kosentka, A.et al. Chiari I malformation and neurofibromatosis type 1. Pediatr Neurol. 2004; 30: 278–80.Google Scholar
Dounas, M., Mercier, F. J., Lhuissier, C. & Benhamou, D.Epidural analgesia for labour in a parturient with neurofibromatosis. Can. J. Anaesth. 1995; 42: 420–2.Google Scholar
Esler, M. D., Durbridge, J. & Kirby, S.Epidural haematoma after dural puncture in a parturient with neurofibromatosis. Br. J. Anaesth. 2001; 87: 932–4.Google Scholar
Choudhary, S., MacKinnon, C. A., Morrissey, G. P. & Tan, S. T.A case of giant nasal pyogenic granuloma gravidarum. J. Craniofac. Surg. 2005; 16: 319–21.Google Scholar
Yuan, K., Wing, L. Y. & Lin, M. T.Pathogenetic roles of angiogenic factors in pyogenic granulomas in pregnancy are modulated by female sex hormones. J. Periodontol. 2002; 73: 701–8.Google Scholar
Choudhary, S., MacKinnon, C. A., Morrissey, G. P. & Tan, S. T.A case of giant nasal pyogenic granuloma gravidarum. J. Craniofac. Surg. 2005; 16: 319–21.Google Scholar
Wang, P. H., Chao, H. T., Lee, W. L.et al. Severe bleeding from a pregnancy tumor. A case report. J. Reprod. Med. 1997; 42: 359–62.Google Scholar
Hayakawa, H., Tara, M., Niina, K. & Osame, M.A clinical study of adult human parvovirus B19 infection. Intern. Med. 2002; 41: 295–9.Google Scholar
Seve, P., Ferry, T., Charhon, A.et al. Systemic manifestations of Parvovirus B19 infections. Rev. Med. Interne. 2004; 25: 740–51.Google Scholar
Severin, M. C., Levy, Y. & Shoenfeld, Y.Systemic lupus erythematosus and parvovirus B-19: casual coincidence or causative culprit?Clin. Rev. Allergy Immunol. 2003; 25: 41–8.Google Scholar
Meyer, O.Parvovirus B19 and autoimmune diseases. Joint Bone Spine 2003; 70: 6–11.Google Scholar
Schwarz, T. F. & Roggendorf, M.Parvovirus infections in dermatology. Z. Hautkr. 1989; 64: 272–3.Google Scholar
Hornsleth, A. & Carlsen, K. M.Parvovirus B19 infections. The cause of fifth disease-erythema infectiosum – can also cause aplastic crises, fetal damage and polyarthritis. Ugeskr. Laeger. 1990; 152: 1354–7.Google Scholar
Miller, E., Fairley, C. K., Cohen, B. J. & Seng, C.Immediate and long term outcome of human parvovirus B19 infection in pregnancy. Br. J. Obstet. Gynaecol. 1998; 105: 174–8.Google Scholar
Harger, J. H., Ernest, J. M., Thurnau, G. R.et al. National Institute of Child Health and Human Development, Network of Maternal-Fetal Medicine Units. Risk factors and outcome of varicella-zoster virus pneumonia in pregnant women. J. Infect. Dis. 2002; 185: 422–7.Google Scholar
Brown, N. W., Parsons, A. P. & Kam, P. C.Anaesthetic considerations in a parturient with varicella presenting for Caesarean section. Anaesthesia 2003; 58: 1092–5.Google Scholar
Gei, A. F., Pacheco, L. D., Vanhook, J. W. & Hankins, G. D.The use of a continuous infusion of epinephrine for anaphylactic shock during labor. Obstet. Gynecol. 2003; 102: 1332–5.Google Scholar
Steere, A. C.Lyme disease. N. Engl. J. Med. 2001; 345: 115–25.Google Scholar
Luman, E. T., Barker, L. E., Shaw, K. M.et al. Timeliness of childhood vaccinations in the United States: days undervaccinated and number of vaccines delayed. J.A.M.A. 2005; 293: 1204–11.Google Scholar
Mastaglia, F. L. & Phillips, B. A.Idiopathic inflammatory myopathies: epidemiology, classification, and diagnostic criteria. Rheum. Dis. Clin. North Am. 2002; 28: 723–41.Google Scholar
Eymard, B.Polymyositis, dermatomyositis and inclusion body myositis, nosological aspects. Presse Med. 2003; 32: 1656–67.Google Scholar
Sarkar, K., Weinberg, C. R., Oddis, C. V.et al. Seasonal influence on the onset of idiopathic inflammatory myopathies in serologically defined groups. Arthritis Rheum. 2005; 52: 2433–8.Google Scholar
Amato, A. A. & Shebert, R. T.Inclusion body myositis in twins. Neurology 1998; 51: 598–600.Google Scholar
Silva, C. A., Sultan, S. M. & Isenberg, D. A.Pregnancy outcome in adult-onset idiopathic inflammatory myopathy. Rheumatology 2003; 42: 1168–72.Google Scholar
Gutierrez, G., Dagnino, R. & Mintz, G.Polymyositis/dermatomyositis and pregnancy. Arthritis Rheum. 1984; 27: 291–4.Google Scholar
Stoelting, R. K. & Dierdorf, S. F. Skin and musculoskeletal diseases. In Stoelting, R. K. & Dierdorf, S. F. (eds.), Anesthesia and Coexisting Disease, 4th edn. Philadelphia: Churchill Livingstone, 2002; p. 514.
Shieh, S., Fang, Y. V., Becker, J. L.et al. Pemphigus, pregnancy, and plasmapheresis. Cutis. 2004; 73: 327–9.Google Scholar
Owen, J. & Hauth, J. C.Polyarteritis nodosa in pregnancy: a case report and brief literature review. Am. J. Obstet. Gynecol. 1989; 160: 606–7.Google Scholar
Reed, N. R. & Smith, M. T.Periarteritis nodosa in pregnancy: report of a case and review of the literature. Obstet. Gynecol. 1980; 55: 381–4.Google Scholar
Burkett, G. & Richards, R.Periarteritis nodosa and pregnancyObstet. Gynecol. 1982; 59: 252–4.Google Scholar
Rabhi, M., Tiev, K. P., Genereau, T. & Cabane, J.Scleroderma and pregnancy. Ann. Med. Interne. 2002; 153: 193–200.Google Scholar
Benson, E. M.Immunologic manipulation for the threatened fetus. Thromb. Res. 2004; 114: 427–34.Google Scholar
Berger, J. R. & Koralnick, I. J.Progressive multifocal leukoencephalopathy and natalizumab – unforeseen consequences. N. Engl. J. Med. 2005; 353: 414–16.Google Scholar
Assche, G., Ranst, M., Sciot, R.et al. Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease. N. Engl. J. Med. 2005; 353: 362–8.Google Scholar
Kleinschmidt-DeMasters, B. K. & Tyler, K. L.Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis. N. Engl. J. Med. 2005; 353: 369–74.Google Scholar
Langer-Gould, A., Atlas, S. W., Green, A. J.et al. Progressive multifocal leukoencephalopathy in a patient treated with natalizumab. N. Engl. J. Med. 2005; 353: 375–81.Google Scholar
Gompels, M. M., Lock, R. J., Abinun, M.et al. C1 inhibitor deficiency: consensus document. Clin. Exp. Immunol. 2005; 139: 379–94.Google Scholar
Griffiths, R. J. & O'Sullivan, G.C1-esterase inhibitor deficiency and elective caesarean section. Int. J. Obstet. Anesth. 2005; 14: 263–4.Google Scholar
Oskay, T., Kutluay, L., Kaptanoglu, A. & Karabacak, O.Autoimmune progesterone dermatitis. Eur. J. Dermatol. 2002; 12: 589–91.Google Scholar
Snyder, J. L. & Krishnaswamy, G.Autoimmune progesterone dermatitis and its manifestation as anaphylaxis: a case report and literature review. Ann. Allergy Asthma Immunol. 2003; 90: 469–77.Google Scholar
O'Rourke, J., Khawaja, N., Loughrey, J. & McKenna, P.Autoimmune progesterone dermatitis in a parturient for emergency caesarean section. Int. J. Obstet. Anesth. 2004; 13: 275–8.Google Scholar
Villeneuve, V., Kaufman, I., Weeks, S. & Deschamps, A.Anesthetic management of a labouring parturient with urticaria pigmentosa. Can. J. Anesth. 2006; 53: 380–4.Google Scholar
Castells, M. C.Mastocytosis: classification, diagnosis, and clinical presentation. Allergy Asthma Proc. 2004; 25: 33–6.Google Scholar
Worobec, A. S., Akin, C., Scott, L. M. & Metcalfe, D. D.Mastocytosis complicating pregnancy. Obstet. Gynecol. 2000; 95: 391–5.Google Scholar
Collada, Garcia J. C., Marin, Pereda R. M., Serrano, Miralles E. & Lopez, Pacheco J. F.Epidural analgesia for labor in a patient with systemic mastocytosis. Rev. Esp. Anestesiol. Reanim. 2000; 47: 326–7.Google Scholar
Donahue, J. G., Lupton, J. B., & Golichowski, A. M.Cutaneous mastocytosis complicating pregnancy. Obstet. Gynecol. 1995; 85: 813–15.Google Scholar
Vaughan, S. T. & Jones, G. N.Systemic mastocytosis presenting as profound cardiovascular collapse during anaesthesia. Anaesthesia 1998; 53: 804–7.Google Scholar
Auvray, L., Letourneau, B. & Freysz, M.Mastocytosis: general anesthesia with remifentanil and sevoflurane. Ann. Fr. Anesth. Reanim. 2001; 20: 635–8.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

  • Dermatoses
    • By Robert S. F. McKay, Clinical Professor and Chair, Department of Anesthesiology, University of Kansas, School of Medicine – Wichita, Wichita, KS, USA, John E. Schlicher, Private Practice, Dermatologist, Beatrice Keller Clinic, Sun City West, AZ, USA
  • Edited by David R. Gambling, University of California, San Diego, M. Joanne Douglas, University of British Columbia, Vancouver, Robert S. F. McKay, University of Kansas
  • Book: Obstetric Anesthesia and Uncommon Disorders
  • Online publication: 19 October 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511544552.020
Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

  • Dermatoses
    • By Robert S. F. McKay, Clinical Professor and Chair, Department of Anesthesiology, University of Kansas, School of Medicine – Wichita, Wichita, KS, USA, John E. Schlicher, Private Practice, Dermatologist, Beatrice Keller Clinic, Sun City West, AZ, USA
  • Edited by David R. Gambling, University of California, San Diego, M. Joanne Douglas, University of British Columbia, Vancouver, Robert S. F. McKay, University of Kansas
  • Book: Obstetric Anesthesia and Uncommon Disorders
  • Online publication: 19 October 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511544552.020
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Dermatoses
    • By Robert S. F. McKay, Clinical Professor and Chair, Department of Anesthesiology, University of Kansas, School of Medicine – Wichita, Wichita, KS, USA, John E. Schlicher, Private Practice, Dermatologist, Beatrice Keller Clinic, Sun City West, AZ, USA
  • Edited by David R. Gambling, University of California, San Diego, M. Joanne Douglas, University of British Columbia, Vancouver, Robert S. F. McKay, University of Kansas
  • Book: Obstetric Anesthesia and Uncommon Disorders
  • Online publication: 19 October 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511544552.020
Available formats
×