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Case 91 - Chest wall sarcoma

from Section 9 - Musculoskeletal imaging

Published online by Cambridge University Press:  05 June 2014

Vanessa Starr
Affiliation:
Santa Clara Valley Medical Center
Bo Yoon Ha
Affiliation:
Santa Clara Valley Medical Center
Heike E. Daldrup-Link
Affiliation:
Lucile Packard Children's Hospital, Stanford University
Beverley Newman
Affiliation:
Lucile Packard Children's Hospital, Stanford University
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Summary

Imaging description

A 15-year-old boy presented with left-sided chest pain and a palpable chest wall mass. PA radiograph of the chest demonstrated osseous expansion and periosteal reaction in the left mid 8th rib and a large associated soft tissue mass (Fig. 91.1a). Axial contrast-enhanced CT of the chest demonstrated a heterogeneous soft tissue mass along the left chest wall. There was expansion, destruction, and periosteal reaction of the involved rib (Fig. 91.1b, c). An MRI of the abdomen, obtained to evaluate for metastases, was negative and also included the lower chest (Fig. 91.1d, e, f). This demonstrated a large heterogeneous T2 bright mass surrounding the left lower rib. The mass and marrow of the affected rib demonstrated restricted diffusion (bright signal on diffusion-weighted imaging [DWI] with dark signal on ADC map). Bone scan (not shown) did not demonstrate any metastases. Ewing’s sarcoma of the chest wall was suggested as the most likely diagnosis. Subsequent pathology defined the lesion as an undifferentiated sarcoma of the chest wall.

Type
Chapter
Information
Pearls and Pitfalls in Pediatric Imaging
Variants and Other Difficult Diagnoses
, pp. 370 - 373
Publisher: Cambridge University Press
Print publication year: 2014

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References

Erlemann, R, Sciuk, J, Bosse, A, et al. Response of osteosarcoma and Ewing sarcoma to preoperative chemotherapy: assessment with dynamic and static MR imaging and skeletal scintigraphy. Radiology 1990;175(3):791–6.CrossRefGoogle ScholarPubMed
Jedlicka, P. Ewing Sarcoma, an enigmatic malignancy of likely progenitor cell origin, driven by transcription factor oncogenic fusions. Int J Clin Exp Pathol 2010;3(4):338–47.Google ScholarPubMed
Kaste, SC, Strouse, PJ, Fletcher, BD, et al. Benign and malignant bone tumors. In: Slovis, TL, ed. Caffey’s Pediatric Diagnostic Imaging, 11th edition. Philadelphia: Mosby Elsevier, 2008; 2912–69.CrossRefGoogle Scholar
Reinus, WR, Gilula, LA. Radiology of Ewing’s sarcoma: Intergroup Ewing’s Sarcoma Study (IESS). Radiographics 1984;4:929–44.CrossRefGoogle Scholar

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