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Chapter 24 - Musculoskeletal oncology

from Section 5 - Applied Basic Sciences

Published online by Cambridge University Press:  15 November 2019

By
Tomas B. Beckingsale  and
Kanishka Milton Ghosh
Edited by
Paul A. Banaszkiewicz  and
Deiary F. Kader
Paul A. Banaszkiewicz
Affiliation:
Queen Elizabeth Hospital, Gateshead
Deiary F. Kader
Affiliation:
Queen Elizabeth Hospital, Gateshead
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Summary

As in all other areas of the viva examinations, knowing basic definitions gives you an easy starting point when answering questions and gives the impression to the examiners that you have both a logical and clear thought process, and are in command of the subject matter.

A growth or swelling, which enlarges by cellular proliferation more rapidly than surrounding normal tissue and continues to enlarge after the initiating stimuli cease. Usually lacks structural organization and functional coordination with normal tissues and serves no useful purpose to the host.

Type
Chapter
Information
Postgraduate Orthopaedics
Viva Guide for the FRCS (Tr & Orth) Examination
 , pp. 586 - 597
Publisher: Cambridge University Press
Print publication year: 2019

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References

Bibliography/Further reading

Welker, JA, Henshaw, RM, Jelinek, J, Shmookler, BM, Malawer, MM. The percutaneous needle biopsy is safe and recommended in the diagnosis of musculoskeletal masses. Cancer. 2000;89(12):2677–2686.3.0.CO;2-L>CrossRefGoogle ScholarPubMed
Enneking, WF, Spanier, SS, Malawer, MM. The effect of the anatomic setting on the results of surgical procedures for soft parts sarcoma of the thigh. Cancer. 1981;47(5):1005–1022.3.0.CO;2-9>CrossRefGoogle ScholarPubMed
Enneking, WF, Spanier, SS, Goodman, MA. Current concepts review. The surgical staging of musculoskeletal sarcoma. J Bone Joint Surg Am. 1980;62(6):1027–1030.CrossRefGoogle ScholarPubMed
NCCN. National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology: Soft Tissue Sarcoma. V.2.2008. National Comprehensive Cancer Network. 2008.Google Scholar
Bullough, PG. Orthopaedic Pathology. Fourth Edition. Edinburgh: Mosby; 2007.Google Scholar
Beckingsale, TB, Gerrand, CH. Osteosarcoma. Orthop Trauma. 2010;24(5):321–331.CrossRefGoogle Scholar
Meyers, PA, Schwartz, CL, Krailo, MD, et al. Osteosarcoma: the addition of muramyl tripeptide to chemotherapy improves overall survival – a report from the Children’s Oncology Group. J Clin Oncol. 2008;26:633–638.CrossRefGoogle ScholarPubMed
Beckingsale, TB, Gerrand, CH. The management of soft-tissue sarcomas. Orthop Trauma. 2009;23(4):240–247.CrossRefGoogle Scholar
Jeys, LM, Thorne, CJ, Parry, M, Gaston, CL, Sumanthi, VP, Grimer, JR. A novel system for the surgical staging of primary high-grade osteosarcoma: the Birmingham classification. Clin Orthop Relat Res. 2017;475(3):842–850.CrossRefGoogle ScholarPubMed
Yamagishi, T, Kawashima, H, Ogose, A, et al. Receptor-activator of nuclear kappa b ligand expression as a new therapeutic target in primary bone tumors. PLoS ONE. 2016;11(5):e0154680.CrossRefGoogle Scholar
Van der Hejden, L, Dijkstra, PDS, Blay, JY, Gelderblom, H. Giant cell tumour of bone in the denosumab era. Eur J Cancer. 2017;77:75–73.Google Scholar
Dubory, A, Missenard, G, Domont, J, Court, C. Interest of denosumab for the treatment of giant cell tumours and aneurysmal bone cysts of the spine. About nine cases. Spine (Phila Pa 1976). 2016;41(11):E654–660.CrossRefGoogle ScholarPubMed

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