Many people turn to their religious beliefs and faith community for comfort when the worst happens. Even people who do not identify with a religion may rely on their spirituality, a sense of connection to something greater, to help them cope. From a healthcare chaplain responding to the COVID-19 pandemic to a mental health worker recovering from a brutal assault, you will hear examples of how people have turned to religion and spirituality to heal, recover, and grow. We also tell the story of Dr. Southwick's ancestors, early settlers in the United States who faced religious persecution with unwaivering commitment. We highlight the benefits of prayer, meditation, and other spiritual practices.