Albert, M. & Cohen, C. (1992) The test for severe impairment: an instrument for the assessment of patients with severe cognitive dysfunction. Journal of the American Geriatric Society, 40, 449–453.
Aylward, E. H., Burt, D. B., Thorpe, L. U.
et al (1997) Diagnosis of dementia in individuals with intellectual disability. Journal of Intellectual Disability Research, 41, 152–164.
Aylward, E. H., Li, Q., Honeycutt, N. A.
et al (1999) MRI volumes of the hippocampus and amygdala in adults with Down's syndrome with and without dementia. American Journal of Psychiatry, 156, 564–568.
Bouman, W. P. & Pinner, G. (2002) Use of atypical antipsychotic drugs in old age psychiatry. Advances in Psychiatric Treatment, 8, 49–58.
Burt, D. B. & Aylward, E. H. (2000) Test battery for the diagnosis of dementia in individuals with intellectual disability. Journal of Intellectual Disability Research, 44, 175–180.
Cooper, S. A. & Prasher, V. P. (1998) Maladaptive behaviours and symptoms of dementia in adults with Down's syndrome compared with adults with intellectual disabilities of other aetiologies. Journal of Intellectual Disability Research, 42, 293–300.
Cosgrave, M. P., Tyrrell, J., McCarron, M.
et al (2000) A five year follow-up study of dementia in persons with Down's syndrome: early symptoms and patterns of deterioration. Irish Journal of Psychological Medicine, 17, 5–11.
Evenhuis, H. M. (1990) The natural history of dementia in Down's syndrome. Archives of Neurology, 47, 263–267.
Evenhuis, H. M. (1996) Further evaluation of the Dementia Questionnaire for Persons with Mental Retardation (DMR). Journal of Intellectual Disability Research, 40, 369–373.
Fraser, B. (1999) Psychopharmacology and people with learning disability. Advances in Psychiatric Treatment, 5, 471–477.
Gedye, A. (1995) Dementia Scale for Down's Syndrome. Manual. Vancouver, BC: Gedye Research and Consulting.
Hemingway-Eltomey, J. M. & Lerner, A. J. (1999) Adverse effects of donepezil in treating Alzheimer's disease associated with Down's syndrome. American Journal of Psychiatry, 156, 1470.
Holland, A. J., Hon, J., Huppert, F. A.
et al (1998) Population-based study of the prevalence and presentation of dementia in adults with Down's syndrome. British Journal of Psychiatry, 172, 493–498.
Holland, A. J., Hon, J., Huppert, A.
et al (2000) Incidence and course of dementia in people with Down's syndrome: findings from a population-based study. Journal of Intellectual Disability Research, 44, 138–146.
Kishnani, P. S., Spiridigliozzi, G. A., Heller, J. H.
et al (2001) Donepezil for Down's syndrome (comment). American Journal of Psychiatry, 158, 143.
Lawlor, B. A., McCarron, M., Wilson, G.
et al (2001) Temporal lobe-oriented CT scanning and dementia in Down's syndrome. International Journal of Geriatric Psychiatry, 16, 427–429.
Mann, D. M., Iwatsubo, T., Ihara, Y.
et al (1996) Predominant deposition of amyloid-beta 42(43) in plaques in cases of Alzheimer's disease and hereditary cerebral haemorrhage associated with mutations in the APP gene. American Journal of Pathology, 148, 1257–1266.
Moss, M. B., Albert, M. S., Butters, N.
et al (1986) Differential patterns of memory loss among patients with Alzheimer's disease, Huntington's disease, and alcoholic Korsakoff's syndrome. Archives of Neurology, 43, 239–246.
Oliver, C., Crayton, L., Holland, A.
et al (1998) A four year prospective study of age-related cognitive change in adults with Down's syndrome. Psychological Medicine, 28, 1365–1377.
Prasher, V. P., Huxley, A. & Haque, M. S. (2002) A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Down syndrome and Alzheimer's disease. Pilot study. International Journal of Geriatric Psychiatry, 17, 270–278.
Rabe, A., Wisniewski, K. E., Schupf, N.
et al (1990) Relationship of Down's syndrome to Alzheimer's disease. In Application of Basic Neuroscience to Child Psychiatry (eds Deutsch, S. I., Weizman, A. & Weizman, R.) pp. 325–340. New York: Plenum Press.
Reiss, S., Levitan, G. W. & Szyszko, J. (1982) Emotional disturbance and mental retardation: diagnostic overshadowing. American Journal of Mental Deficiency, 86, 567–574.
Royal College of Psychiatrists (2001) DC–LD [Diagnostic Criteria for Psychiatric Disorders for Use with Adults with Learning Disabilities/Mental Retardation] (Occasional Paper OP48). London: Gaskell.
Schupf, N. (2002) Genetic and host factors for dementia in Down's syndrome. British Journal of Psychiatry, 180, 405–410.
Schupf, N., Kapell, D., Nightingale, B.
et al (2001) Specificity of the fivefold increase in Alzheimer's disease in mothers of adults with Down syndrome. Neurology, 57, 979–984.
Seltzer, G. B., Schupf, N. & Wu, H. S. (2001) A prospective study of menopause in women with Down syndrome. Journal of Intellectual Disability Research, 45, 1–7.
Simard, M. & Van Reekum, R. (2001) Dementia with Lewy bodies in Down's syndrome. International Journal of Geriatric Psychiatry, 16, 311–320.
Temple, V., Jozsvai, E., Konstantareas, M. M.
et al (2001) Alzheimer dementia in Down's syndrome: the relevance of cognitive ability. Journal of Intellectual Disability Research, 45, 47–55.
Tyrell, J., Cosgrave, M., McCarron, M.
et al (2001) Dementia in people with Down's syndrome. International Journal of Geriatric Psychiatry, 16, 1168–1174.
Visser, F. E., Aldenkamp, A. P., Van Huffelen, A. C.
et al (1997) Prospective study of the prevalence of Alzheimer-type dementia in institutionalized individuals with Down syndrome. American Journal on Mental Retardation, 101, 400–412.
Wisniewski, K. E., Wisniewski, H. M. & Wen, G. Y. (1985) Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome. Annals of Neurology, 17, 278–282.