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Biochemical aspects of malabsorption in marasmus: effect of dietary rehabilitation

Published online by Cambridge University Press:  24 July 2007

H. C. Mehta ,
A. S. Saini ,
Harjit Singh  and
P. S. Dhatt
H. C. Mehta
Affiliation:
Department of Biochemistry and Medical College and Hospital, Rohtak-124001, Haryana, India
A. S. Saini
Affiliation:
Department of Biochemistry and Medical College and Hospital, Rohtak-124001, Haryana, India
Harjit Singh
Affiliation:
Department of Biochemistry and Medical College and Hospital, Rohtak-124001, Haryana, India
P. S. Dhatt
Affiliation:
Department of Paediatrics, Medical College and Hospital, Rohtak-124001, Haryana, India
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Abstract

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1. Sixty marasmic children were investigated for the absorption of xylose, proteins and fats. Their duodenal juice samples were also analysed for bile salts and microflora.

2. The marasmic children were then studied in three groups of twenty by allocating them to three different dietary schedules: a high-protein diet (30% of the total energy from protein), a high-fat diet (40% of the total energy from fat) and a high-carbohydrate diet (70% of the total energy from carbohydrate) for 2 weeks and the previous measurements repeated.

3. Whereas the high-fat diet resulted in improved fat absorption, along with an increase in total and conjugated bile acids, and the high-carbohydrate diet led to improved xylose absorption, the diet rich in protein resulted in an improvement in the absorption of all three dietary ingredients. It appears that a high-protein diet improves the overall absorption process by improving the intestinal environment as a whole, while high-carbohydrate and high-fat diets bring about adaptive changes related to the respective absorptive processes.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 54 , Issue 3 , November 1985 , pp. 567 - 575
Copyright
Copyright © The Nutrition Society 1985

References

Anthony, W. L. & Behar, W. T. (1964). Journal of Chromatography 13, 567–570.CrossRefGoogle Scholar
Barbezat, G. O. & Hansen, J. D. L. (1968). Paediatrics 42, 77–92.CrossRefGoogle Scholar
Dugdale, A. E. (1971). American Journal of Clinical Nutrition 24, 174–176.CrossRefGoogle Scholar
Gomez, F., Ramos-Galven, R., Cravioto, J. & Frenk, S. (1954). Paediatrics 13, 548–554.CrossRefGoogle Scholar
Gould, B. S. & Schwachman, H. (1956). American journal of diseases of childhood 91, 584–587.CrossRefGoogle Scholar
Jones, W. O. & disant Agnese, P. A. (1963). Journal of Paediatrics 62, 44–49.CrossRefGoogle Scholar
Mata, L. J., Jimenz, F., Cordon, M., Rosales, R., Prera, E., Schneider, R. E. & Viteri, F. (1972). American journal of Clinical Nutrition 25, 1118–1126.CrossRefGoogle Scholar
Mehta, H. C., Saini, A. S., Singh, H. & Dhatt, P. S. (1984). Indian Paediatrics 21, 149–154.Google Scholar
Mehta, H. C., Saini, A. S., Singh, H. & Dhatt, P. S. (1984). British Journal of Nutrition 51, 1–6.CrossRefGoogle Scholar
Mezey, E. & Potter, J. J. (1976). Johns Hopkins Medical Journal 138, 7–12.Google Scholar
O'Sullivan, D. J., Fitzgerald, M. G., Meynall, M. J. & Maline, J. M. (1960). Journal of Clinical Pathology 13, 527–528.CrossRefGoogle Scholar
Reboud, J. P., Marchis Mouren, G., Pasero, L., Cozzonne, A. & Desnuelle, P. (1960). Biochemical Biophysical Research Communications 2, 94–99.Google Scholar
Roe, J. H. & Rice, E. W. (1948). Journal of Biological Chemistry 173, 507–512.CrossRefGoogle Scholar
Schneider, R. E. & Viteri, F. E. (1974). American Journal of Clinical Nutrition 27, 788–796.CrossRefGoogle Scholar
Stanfield, J. P. (1976). In Protein energy malnutrition, p. 91 [Alleyne, G.A. O.,Hay, R. W.,Picou, D. L.,Stanfield, J.P. and Whitehead, R. G., editors]. London: Edward Arnold Publications.Google Scholar
Thompson, M. D. & Trowell, H. C. (1952). Lancet i, 1031–1035.CrossRefGoogle Scholar
Van de Kamer, J. H., Weijers, H. A. & Dicke, W. K. (1949). Journal of Biological Chemistry 177, 347–355.CrossRefGoogle Scholar
Viteri, F., Behar, M., Arroyave, G. & Scrimshaw, N. S. (1964). In Mammalian protein metabolism, vol. 2, pp. 523–568 [Munro, H. N. andAllison, J. B., editors]. New york: Academic press.CrossRefGoogle Scholar
Viteri, F. E., Flores, J. M., Alvarado, J. & Behar, M. (1973). American Journal of Digestive Diseases 18, 201–211.CrossRefGoogle Scholar
Viteri, F. E. & Schneider, R. E. (1974). Medical Clinics of North America 58, 1487–1505.CrossRefGoogle Scholar
Zoppi, G., Andreotti, G., Pajno-Ferrara, F., Njal, D. M. & Gaburro, D. (1972). Paediatric Research 6, 880–886.CrossRefGoogle Scholar
Zoppi, G., Andreotti, G., Pajno-Ferrara, F., Njal, D. M. & Gaburro, D. (1973). Paediatric Research 7, 198–203.CrossRefGoogle Scholar