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Calcium plus vitamin D supplementation and fat mass loss in female very low-calcium consumers: potential link with a calcium-specific appetite control

  • Geneviève C. Major (a1), Francine P. Alarie (a1), Jean Doré (a1) and Angelo Tremblay (a1)
Abstract

This randomized, double-blind, placebo-controlled study was conducted to compare the effect of a 15-week weight-reducing programme ( − 2900 kJ/d) coupled with a calcium plus vitamin D (calcium+D) supplementation (600 mg elemental calcium and 5 μg vitamin D, consumed twice a day) or with a placebo, on body fat and on spontaneous energy/macronutrient intake. Sixty-three overweight or obese women (mean age 43 years, mean BMI 32 kg/m2) reporting a daily calcium intake < 800 mg participated in present study. Anthropometric variables, resting energy expenditure and spontaneous energy intake were measured before and after the 15-week programme. The calcium+D supplementation induced no statistically significant increase in fat mass loss in response to the programme. However, when analyses were limited to very low-calcium consumers only (initial calcium intake ≤ 600 mg/d, n 7 for calcium+D, n 6 for placebo), a significant decrease in body weight and fat mass (P < 0·01) and in spontaneous dietary lipid intake (P < 0·05) was observed in the calcium+D but not in the placebo group. In very low-calcium consumers, change in fat mass was positively correlated with change in lipid intake. During the weight-reducing programme, a calcium+D supplementation was necessary in female overweight/obese very low-calcium consumers to reach significant fat mass loss that seemed to be partly explained by a decrease in lipid intake. We propose that this change in lipid intake could be influenced by a calcium-specific appetite control.

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Corresponding author
*Corresponding author: Dr Angelo Tremblay, fax +1 418 656 2441, email angelo.tremblay@kin.msp.ulaval.ca
References
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1Zemel MB, Thompson W, Milstead A, Morris K & Campbell P (2004) Calcium and dairy acceleration of weight and fat loss during energy restriction in obese adults. Obes Res 12, 582590.
2Zemel MB, Richards J, Mathis S, Milstead A, Gebhardt L & Silva E (2005) Dairy augmentation of total and central fat loss in obese subjects. Int J Obes (Lond) 29, 391397.
3Bowen J, Noakes M & Clifton PM (2005) Effect of calcium and dairy foods in high protein, energy-restricted diets on weight loss and metabolic parameters in overweight adults. Int J Obes (Lond) 29, 957965.
4Jacqmain M, Doucet E, Despres JP, Bouchard C & Tremblay A (2003) Calcium intake, body composition, and lipoprotein-lipid concentrations in adults. Am J Clin Nutr 77, 14481452.
5Shi H, Dirienzo D & Zemel MB (2001) Effects of dietary calcium on adipocyte lipid metabolism and body weight regulation in energy-restricted aP2-agouti transgenic mice. FASEB J 15, 291293.
6Zemel MB, Shi H, Greer B, Dirienzo D & Zemel PC (2000) Regulation of adiposity by dietary calcium. FASEB J 14, 11321138.
7Shi H, Norman AW, Okamura WH, Sen A & Zemel MB (2002) 1α,25-Dihydroxyvitamin D3 inhibits uncoupling protein 2 expression in human adipocytes. FASEB J 16, 18081810.
8Melanson EL, Donahoo WT, Dong F, Ida T & Zemel MB (2005) Effect of low- and high-calcium dairy-based diets on macronutrient oxidation in humans. Obes Res 13, 21022112.
9Jacobsen R, Lorenzen JK, Toubro S, Krog-Mikkelsen I & Astrup A (2005) Effect of short-term high dietary calcium intake on 24-h energy expenditure, fat oxidation, and fecal fat excretion. Int J Obes (Lond) 29, 292301.
10Tordoff MG (2001) Calcium: taste, intake, and appetite. Physiol Rev 81, 15671597.
11Paradis S & Cabanac M (2005) Calcium deficiency cannot induce obesity in rats. Physiol Behav 85, 259264.
12Tremblay A, Sévigny J, Leblanc C & Bouchard C (1983) The reproducibility of a three-day dietary record. Nutr Res 3, 819830.
13Government of Canada (1990) The Canadian Nutrient File. Ottawa, Canada: Health and Welfare Canada.
14Major GC, Alarie F, Dore J, Phouttama S & Tremblay A (2007) Supplementation with calcium+vitamin D enhances the beneficial effect of weight loss on plasma lipid and lipoprotein concentrations. Am J Clin Nutr 85, 5459.
15Berube-Parent S, Pelletier C, Dore J & Tremblay A (2005) Effects of encapsulated green tea and Guarana extracts containing a mixture of epigallocatechin-3-gallate and caffeine on 24 h energy expenditure and fat oxidation in men. Br J Nutr 94, 432436.
16Drapeau V, Blundell J, Therrien F, Lawton C, Richard D & Tremblay A (2005) Appetite sensations as a marker of overall intake. Br J Nutr 93, 273280.
17Arvaniti K, Richard D & Tremblay A (2000) Reproducibility of energy and macronutrient intake and related substrate oxidation rates in a buffet-type meal. Br J Nutr 83, 489495.
18Thompson WG, Rostad Holdman N, Janzow DJ, Slezak JM, Morris KL & Zemel MB (2005) Effect of energy-reduced diets high in dairy products and fiber on weight loss in obese adults. Obes Res 13, 13441353.
19Lorenzen JK, Molgaard C, Michaelsen KF & Astrup A (2006) Calcium supplementation for 1 y does not reduce body weight or fat mass in young girls. Am J Clin Nutr 83, 1823.
20Hall KD (2006) Computational model of in vivo human energy metabolism during semistarvation and refeeding. Am J Physiol Endocrinol Metab 291, E23E37.
21Hall KD (2008) What is the required energy deficit per unit weight loss? Int J Obes (Lond) 32, 573576.
22Flatt JP (1987) Dietary fat, carbohydrate balance, and weight maintenance: effects of exercise. Am J Clin Nutr 45, 296306.
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British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
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