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Consumption of organic foods and risk of atopic disease during the first 2 years of life in the Netherlands

  • Ischa Kummeling (a1) (a2), Carel Thijs (a1) (a3), Machteld Huber (a4), Lucy P. L. van de Vijver (a4), Bianca E. P. Snijders (a1), John Penders (a3), Foekje Stelma (a1) (a5), Ronald van Ree (a6), Piet A. van den Brandt (a1) and Pieter C. Dagnelie (a3)...
Abstract

We prospectively investigated whether organic food consumption by infants was associated with developing atopic manifestations in the first 2 years of life. The KOALA Birth Cohort Study in the Netherlands (n 2764) measured organic food consumption, eczema and wheeze in infants until age 2 years using repeated questionnaires. Diet was defined as conventional ( < 50 % organic), moderately organic (50–90 % organic) and strictly organic (>90 % organic). Venous blood samples taken from 815 infants at 2 years of age were analysed for total and specific IgE. Multivariate logistic regression models were fitted to control for potential confounding factors. Eczema was present in 32 % of infants, recurrent wheeze in 11 % and prolonged wheezing in 5 %. At 2 years of age, 27 % of children were sensitised against at least one allergen. Of all the children, 10 % had consumed a moderately organic diet and 6 % a strictly organic diet. Consumption of organic dairy products was associated with lower eczema risk (OR 0·64 (95 % CI 0·44, 0·93)), but there was no association of organic meat, fruit, vegetables or eggs, or the proportion of organic products within the total diet with the development of eczema, wheeze or atopic sensitisation. Further studies to substantiate these results are warranted.

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Corresponding author
*Corresponding author: Dr Carel Thijs, fax +31 43 3884128, email C.Thijs@epid.unimaas.nl
References
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1Maziak W, Behrens T, Brasky TM, Duhme H, Rzehak P, Weiland SK & Keil U (2003) Are asthma and allergies in children and adolescents increasing? Results from ISAAC phase I and phase III surveys in Munster. Germany. Allergy 58, 572579.
2Beasley R, Crane J, Lai CK & Pearce N (2000) Prevalence and etiology of asthma. J Allergy Clin Immunol 105, S466S472.
3The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee (1998) Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. Lancet 351, 12251232.
4Alm JS, Swartz J, Lilja G, Scheynius A & Pershagen G (1999) Atopy in children of families with an anthroposophic lifestyle. Lancet 353, 14851488.
5Alfven T, Braun-Fahrlander C, Brunekreef B, et al. (2006) Allergic diseases and atopic sensitization in children related to farming and anthroposophic lifestyle – the PARSIFAL study. Allergy 61, 414421.
6Magnusson MK, Arvola A, Hursti UK, Aberg L & Sjoden PO (2003) Choice of organic foods is related to perceived consequences for human health and to environmentally friendly behaviour. Appetite 40, 109117.
7Lockie S, Lyons K, Lawrence G & Grise J (2004) Choosing organics: a path analysis of factors underlying the selection of organic food among Australian consumers. Appetite 43, 135146.
8Williams PR & Hammitt JK (2001) Perceived risks of conventional and organic produce: pesticides, pathogens, and natural toxins. Risk Anal 21, 319330.
9Mäder P, Fliessbach A, Dubois D, Gunst L, Fried P & Niggli U (2002) Soil fertility and biodiversity in organic farming. Science 296, 16941697.
10Williams CM (2002) Nutritional quality of organic food: shades of grey or shades of green? Proc Nutr Soc 61, 1924.
11Jahreis G, Fritsche J & Steinhart H (1997) Conjugated linoleic acid in milk fat: high variation depending on production system. Nutr Res 17, 14791484.
12Bergamo P, Fedele E, Iannibelli L & Marzillo G (2003) Fat-soluble vitamin contents and fatty acid composition in organic and conventional Italian dairy products. Food Chem 82, 625631.
13Litonjua AA, Rias-Shiman SL, Ly NP, Tantisira KG, Rich-Edwards JW, Camagro CA, Weiss ST, Gillman MW & Gold DR (2006) Maternal antioxidant intake in pregnancy and wheezing illnesses in children at 2 y of age. Am J Clin Nutr 84, 903911.
14Wijga AH, van Houwelingen AC, Kerkhof M, Tabak C, de Jongste JC, Gerritsen J, Neijens HJ, Boshuizen HC & Brunekreef B (2006) Breast milk fatty acids and allergic disease in preschool children: the Prevention and Incidence of Asthma and Mite Allergy birth cohort study. J Allergy Clin Immunol 117, 440447.
15Oddy WH, Pal S, Kusel MM, et al. (2006) Atopy, eczema and breast milk fatty acids in a high-risk cohort of children followed from birth to 5 yr. Pediatr Allergy Immunol 17, 415.
16Kummeling I, Thijs C, Penders J, et al. (2005) Etiology of atopy in infancy: the KOALA Birth Cohort Study. Pediatr Allergy Immunol 16, 679684.
17Bastiaanssen JM, de Bie RA, Bastiaenen CH, Heuts A, Kroese ME, Essed GG & van den Brandt PA (2005) Etiology and prognosis of pregnancy-related pelvic girdle pain; design of a longitudinal study. BMC Public Health 5, 18.
18Asher MI, Keil U, Anderson HR, et al. (1995) The International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. Eur Respir J 8, 483491.
19Stallman PJ & Aalberse RC (1977) Estimation of basophil-bound IgE by quantitative immunofluorescence microscopy. Int Arch Allergy Appl Immunol 54, 918.
20Akkerdaas JH, Wensing M, Asero R, Fernandez Rivas M, Knulst AC, Bolhaar S, Hefle SL, Aalberse RC & van Ree R (2005) IgE binding to pepsin-digested food extracts. Int Arch Allergy Immunol 138, 203208.
21Schuurman J, Perdok GJ, Lourens TE, Parren PW, Chapman MD & Aalberse RC (1997) Production of a mouse/human chimeric IgE monoclonal antibody to the house dust mite allergen Der p 2 and its use for the absolute quantification of allergen-specific IgE. J Allergy Clin Immunol 99, 545550.
22Floistrup H, Swartz J, Bergstrom A, et al. (2006) Allergic disease and sensitisation in Steiner school children. J Allergy Clin Immunol 117, 5966.
23Rist L, Mueller A, Barthel C, et al. (2007) Influence of organic diet on the amount of conjugated linoleic acids in breast milk of lactating women in the Netherlands. Br J Nutr 97, 735743.
24Koopman LP, Brunekreef B, de Jongste JC & Neijens HJ (2001) Definition of respiratory symptoms and disease in early childhood in large prospective birth cohort studies that predict the development of asthma. Pediatr Allergy Immunol 12, 118124.
25Illi S, von Mutius E, Lau S, Nickel R, Gruber C, Niggemann B & Wahn U (2004) The natural course of atopic dermatitis from birth to age 7 years and the association with asthma. J Allergy Clin Immunol 113, 925931.
26Henderson J, North K, Griffiths M, Harvey I & Golding J (1999) Pertussis vaccination and wheezing illnesses in young children: prospective cohort study. The Longitudinal Study of Pregnancy and Childhood Team. BMJ 318, 11731176.
27Kusel MM, Holt PG, de Klerk N & Sly PD (2005) Support for 2 variants of eczema. J Allergy Clin Immunol 116, 10671072.
28Riedler J, Braun-Fahrländer C, Eder W, Schreuer M, Waser M, Maisch S, Carr D, Schierl R, Nowak D & von Mutius E (2001) Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey. Lancet 358, 11291133.
29Wickens K, Lane JM, Fitzharris P, Siebers R, Riley G, Douwes J, Smith T & Crane J (2002) Farm residence and exposures and the risk of allergic diseases in New Zealand children. Allergy 57, 11711179.
30Perkin MR & Strachan DP (2006) Which aspects of the farming lifestyle explain the inverse association with childhood allergy? J Allergy Clin Immunol 117, 13741381.
31Suhren G, Hesselbarth H, Heeschen W & Sudi J (1986) Evaluation of the lipopolysaccharide (LPS) content as determined by the limulus test in milk and milk products II: raw milk and influences of technological procedures. Milhwissenschaft 41, 156160.
32Adriaansen-Tennekes R, Bloksma J, Huber MAS, Baars T, de Wit J & Baars EW (2005) Biologische Producten en Gezondheid. Resultaten Melkonderzoek (Organic Products and Health. Results of Milk Research), publication GVV06. Driebergen, the Netherlands: Louis Bolk Instituut.
33Voorrips LE, Brants HA, Kardinaal AF, Hiddink GJ, van den Brandt PA & Goldbohm RA (2002) Intake of conjugated linoleic acid, fat, and other fatty acids in relation to postmenopausal breast cancer: the Netherlands Cohort Study of Diet and Cancer. Am J Clin Nutr 76, 873882.
34Sausenthaler S, Kompauer I, Borte M, Herbarth O, Schaaf B, von Berg A, Zutavern A & Heinrich J (2006) Margarine and butter consumption, eczema and allergic sensitisation in children. The LISA birth cohort study. Pediatr Allergy Immunol 17, 8593.
35Bolte G, Frye C, Hoelscher B, Meyer I, Wjst M & Heinrich J (2001) Margarine consumption and allergy in children. Am J Respir Crit Care Med 163, 277279.
36Dunder T, Kuikka L, Turtinen J, Rasanen L & Uhari M (2001) Diet, serum fatty acids, and atopic diseases in childhood. Allergy 56, 425428.
37von Mutius E, Weiland SK, Fritzsch C, Duhme H & Keil U (1998) Increasing prevalence of hay fever and atopy among children in Leipzig, East Germany. Lancet 351, 862866.
38Wijga AH, Smit HA, Kerkhof M, de Jongste JC, Gerritsen J, Neijens HJ, Boshuizen HC & Brunekreef B (2003) Association of consumption of products containing milk fat with reduced asthma risk in pre-school children: the PIAMA birth cohort study. Thorax 58, 567572.
39von Ehrenstein OS, von Mutius E, Illi S, Baumann L, Bohm O & von Kries R (2000) Reduced risk of hay fever and asthma among children of farmers. Clin Exp Allergy 30, 187193.
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British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
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