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Effect of increasing dietary calcium through supplements and dairy food on body weight and body composition: a meta-analysis of randomised controlled trials

  • Alison O. Booth (a1), Catherine E. Huggins (a2), Naiyana Wattanapenpaiboon (a1) and Caryl A. Nowson (a1)
Abstract

This meta-analysis of randomised controlled trials assessed the effect of Ca on body weight and body composition through supplementation or increasing dairy food intake. Forty-one studies met the inclusion criteria (including fifty-one trial arms; thirty-one with dairy foods (n 2091), twenty with Ca supplements (n 2711). Ca intake was approximately 900 mg/d higher in the supplement groups compared with control. In the dairy group, Ca intake was approximately 1300 mg/d. Ca supplementation did not significantly affect body weight (mean change ( − 0·17, 95 % CI − 0·70, 0·37) kg) or body fat (mean change ( − 0·19, 95 % CI − 0·51, 0·13) kg) compared to control. Similarly, increased dairy food intake did not affect body weight ( − 0·06, 95 % CI − 0·54, 0·43) kg or body fat change ( − 0·36, 95 % CI − 0·80, 0·09) kg compared to control. Sub-analyses revealed that dairy supplementation resulted in no change in body weight (nineteen studies, n 1010) ( − 0·32, 95 % CI − 0·93, 0·30 kg, P= 0·31), but a greater reduction in body fat (thirteen studies, n 564) ( − 0·96, 95 % CI − 1·46, − 0·46 kg, P < 0·001) in the presence of energy restriction over a mean of 4 months compared to control. Increasing dietary Ca intake by 900 mg/d as supplements or increasing dairy intake to approximately 3 servings daily (approximately 1300 mg of Ca/d) is not an effective weight reduction strategy in adults. There is, however, an indication that approximately 3 servings of dairy may facilitate fat loss on weight reduction diets in the short term.

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Corresponding author
* Corresponding author: Professor C. A. Nowson, fax +61 3 9244 6017, email caryl.nowson@deakin.edu.au
References
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1 World Health Organization (2011) Obesity and Overweight. Geneva: WHO.
2 ThompsonW, HoldmanN, JanzowD, et al. (2005) Effect of energy-reduced diets high in dairy productes and fiber on weight loss in obese adults. Obes Res 13, 13441353.
3 BlackburnG (1995) Effect of degree of weight loss on health benefits. Obes Res 3, S211S216.
4 ShapsesSA, HeshkaS & HeymsfieldSB (2004) Effect of calcium supplementation on weight and fat loss in women. J Clin Endocrinol Metab 89, 632637.
5 HaubMD, SimonsTR, CookCM, et al. (2005) Calcium-fortified beverage supplementation on body composition in postmenopausal women. Nutr J 4, 21.
6 BarbaG & RussoP (2006) Dairy foods, dietary calcium and obesity: a short review of the evidence. Nutr Metab Cardiovasc Dis 16, 445451.
7 TrowmanR, DumvilleJC, HahnS, et al. (2006) A systematic review of the effects of calcium supplementation on body weight. Br J Nutr 95, 10331038.
8 Harvey-BerinoJ, GoldBC, LauberR, et al. (2005) The impact of calcium and dairy product consumption on weight loss. Obes Res 13, 17201726.
9 DaviesKM, HeaneyRP, ReckerRR, et al. (2000) Calcium intake and body weight. J Clin Endocrinol Metab 85, 46354638.
10 LoosRJ, RankinenT, LeonAS, et al. (2004) Calcium intake is associated with adiposity in Black and White men and White women of the HERITAGE Family Study. J Nutr 134, 17721778.
11 ParikhSJ & YanovskiJA (2003) Calcium intake and adiposity. Am J Clin Nutr 77, 281287.
12 MajorGC, ChaputJP, LedouxM, et al. (2008) Recent developments in calcium-related obesity research. Obes Rev 9, 428445.
13 ChristensenR, LorenzenJK, SvithCR, et al. (2009) Effect of calcium from dairy and dietary supplements on faecal fat excretion: a meta-analysis of randomized controlled trials. Obes Rev 10, 475486.
14 JacobsenR, LorenzenJK, ToubroS, et al. (2005) Effect of short-term high dietary calcium intake on 24-h energy expenditure, fat oxidation, and fecal fat excretion. Int J Obes (Lond) 29, 292301.
15 ZemelMB (2003) Mechanisms of dairy modulation of adiposity. J Nutr 133, 252S256S.
16 SzollosiA, NenquinM, Aguilar-BryanL, et al. (2007) Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old β-cells lacking ATP-sensitive K+ channels. J Biol Chem 282, 17471756.
17 PereiraMA, JacobsDRJr, Van HornL, et al. (2002) Dairy consumption, obesity, and the insulin resistance syndrome in young adults: the CARDIA Study. JAMA 287, 20812089.
18 YanovskiJA, ParikhSJ, YanoffLB, et al. (2009) Effects of calcium supplementation on body weight and adiposity in overweight and obese adults: a randomized trial. Ann Intern Med 150, 821829, W145-6.
19 Angeles-AgdeppaI, CapanzanaMV, Li-YuJ, et al. (2010) High-calcium milk prevents overweight and obesity among postmenopausal women. Food Nutr Bull 31, 381390.
20 OnakpoyaIJ, PerryR, ZhangJ, et al. (2011) Efficacy of calcium supplementation for management of overweight and obesity: systematic review of randomized clinical trials. Nutr Rev 69, 335343.
21 AbargoueiAS, JanghorbaniM, Salehi-MarzijaraniM, et al. (2012) Effect of dairy consumption on weight and body composition in adults: a systematic review and meta-analysis of randomized controlled clinical trials. Int J Obes (Lond) 36, 14851493.
22 ChenM, PanA, MalikVS, et al. (2012) Effects of dairy intake on body weight and fat: a meta-analysis of randomized controlled trials. Am J Clin Nutr 96, 735747.
23 Dawson-HughesB, HarrisSS, KrallEA, et al. (1997) Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older. N Engl J Med 337, 670676.
24 TeegardenD, WhiteKM, LyleRM, et al. (2008) Calcium and dairy product modulation of lipid utilization and energy expenditure. Obesity (Silver Spring) 16, 15661572.
25 PittasAG, HarrisSS, StarkPC, et al. (2007) The effects of calcium and vitamin D supplementation on blood glucose and markers of inflammation in nondiabetic adults. Diabetes Care 30, 980986.
26 MoschonisG & ManiosY (2006) Skeletal site-dependent response of bone mineral density and quantitative ultrasound parameters following a 12-month dietary intervention using dairy products fortified with calcium and vitamin D: the Postmenopausal Health Study. Br J Nutr 96, 11401148.
27 KrugerMC, BoothCL, CoadJ, et al. (2006) Effect of calcium fortified milk supplementation with or without vitamin K on biochemical markers of bone turnover in premenopausal women. Nutrition 22, 11201128.
28 CaanB, NeuhouserM, AragakiA, et al. (2007) Calcium plus vitamin D supplementation and the risk of postmenopausal weight gain. Arch Intern Med 167, 893902.
29 GuntherCW, LegowskiPA, LyleRM, et al. (2005) Dairy products do not lead to alterations in body weight or fat mass in young women in a 1-y intervention. Am J Clin Nutr 81, 751756.
30 ManiosY, MoschonisG, KoutsikasK, et al. (2009) Changes in body composition following a dietary and lifestyle intervention trial: the postmenopausal health study. Maturitas 62, 5865.
31 ReidIR, AmesR, MasonB, et al. (2010) Effects of calcium supplementation on lipids, blood pressure, and body composition in healthy older men: a randomized controlled trial. Am J Clin Nutr 91, 131139.
32 HigginsJP & GreenSe (2011) Cochrane Handbook for Systematic Reviews of Interventions: The Cochrane Collaboration . www.cochrane-handbook.org.
33 BarrSI, McCarronDA, HeaneyRP, et al. (2000) Effects of increased consumption of fluid milk on energy and nutrient intake, body weight, and cardiovascular risk factors in healthy older adults. J Am Diet Assoc 100, 810817.
34 BorensteinM, HedgesLV, HigginsJP, et al. (2009) Introduction to Meta Analysis. Chicester: John Wiley and Sons Ltd.
35 BorensteinM & HigginsJP (2013) Meta-analysis and subgroups. Prev Sci 14, 134143.
36 World Health Organization (2008) Worldwide Prevalence of Anaemia 1993–2005. Geneva: WHO.
37 ZemelMB, ThompsonW, MilsteadA, et al. (2004) Calcium and dairy acceleration of weight and fat loss during energy restriction in obese adults. Obes Res 12, 582590.
38 PalaciosC, BertranJJ, RiosRE, et al. (2011) No effects of low and high consumption of dairy products and calcium supplements on body composition and serum lipids in Puerto Rican obese adults. Nutrition 27, 520525.
39 SmilowitzJT, WiestMM, TeegardenD, et al. (2011) Dietary fat and not calcium supplementation or dairy product consumption is associated with changes in anthropometrics during a randomized, placebo-controlled energy-restriction trial. Nutr Metab (Lond) 8, 67.
40 ZemelMB, TeegardenD, LoanMV, et al. (2009) Dairy-rich diets augment fat loss on an energy-restricted diet: a multicenter trial. Nutrients 1, 83100.
41 WagnerG, KindrickS, HertzlerS, et al. (2007) Effects of various forms of calcium on body weight and bone turnover markers in women participating in a weight loss program. J Am Coll Nutr 26, 456461.
42 JensenLB, KollerupG, QuaadeF, et al. (2001) Bone minerals changes in obese women during a moderate weight loss with and without calcium supplementation. J Bone Miner Res 16, 141147.
43 StancliffeRA, ThorpeT & ZemelMB (2011) Dairy attentuates oxidative and inflammatory stress in metabolic syndrome. Am J Clin Nutr 94, 422430.
44 WitbrachtMG, Van LoanM, AdamsSH, et al. (2013) Dairy food consumption and meal-induced cortisol response interacted to influence weight loss in overweight women undergoing a 12-week, meal-controlled, weight loss intervention. J Nutr 143, 4652.
45 TanakaS, UenishiK, IshidaH, et al. (2014) A randomized intervention trial of 24-wk dairy consumption on waist circumference, blood pressure, and fasting blood sugar and lipids in Japanese men with metabolic syndrome. J Nutr Sci Vitaminol 60, 305312.
46 ReidIR, HorneA, MasonB, et al. (2005) Effects of calcium supplementation on body weight and blood pressure in normal older women: a randomized controlled trial. J Clin Endocrinol Metab 90, 38243829.
47 Winters-StoneKM & SnowCM (2004) One year of oral calcium supplementation maintains cortical bone density in young adult female distance runners. Int J Sport Nutr Exerc Metab 14, 717.
48 MajorGC, AlarieFP, DoreJ, et al. (2009) Calcium plus vitamin D supplementation and fat mass loss in female very low-calcium consumers: potential link with a calcium-specific appetite control. Br J Nutr 101, 659663.
49 DoveER, HodgsonJM, PuddeyIB, et al. (2009) Skim milk compared with a fruit drink acutely reduces appetite and energy intake in overweight men and women. Am J Clin Nutr 90, 7075.
50 TsuchiyaA, Almiron-RoigE, LluchA, et al. (2006) Higher satiety ratings following yogurt consumption relative to fruit drink or dairy fruit drink. J Am Diet Assoc 106, 550557.
51 WycherleyTP, MoranLJ, CliftonPM, et al. (2012) Effects of energy-restricted high-protein, low-fat compared with standard-protein, low-fat diets: a meta-analysis of randomized controlled trials. Am J Clin Nutr 96, 12811298.
52 BendtsenLQ, LorenzenJK, BendsenNT, et al. (2013) Effect of dairy proteins on appetite, energy expenditure, body weight, and composition: a review of the evidence from controlled clinical trials. Adv Nutr 4, 418438.
53 TremblayA & GilbertJA (2011) Human obesity: is insufficient calcium/dairy intake part of the problem? J Am Coll Nutr 30, 449S453S.
54 RosenblumJL, CastroVM, MooreCE, et al. (2012) Calcium and vitamin D supplementation is associated with decreased abdominal visceral adipose tissue in overweight and obese adults. Am J Clin Nutr 95, 101108.
55 BoothAO & NowsonCA (2013) Food choices that achieve calcium adequacy in older women. Nutr Diet 70, 300306.
56 ShalilehM, ShidfarF, HaghaniH, et al. (2010) The influence of calcium supplement on body composition, weight loss and insulin resistance in obese adults receiving low calorie diet. J Res Med Sci 15, 191201.
57 ZhuW, CaiD, WangY, et al. (2013) Calcium plus vitamin D3 supplementation facilitated fat loss in overweight and obese college students with very-low calcium consumption: a randomized controlled trial. Nutr J 12, 8.
58 BowenJ, NoakesM & CliftonPM (2004) A high dairy protein, high-calcium diet minimizes bone turnover in overweight adults during weight loss. J Nutr 134, 568573.
59 FrestedtJL, ZenkJL, KuskowskiMA, et al. (2008) A whey-protein supplement increases fat loss and spares lean muscle in obese subjects: a randomized human clinical study. Nutr Metab (Lond) 5, 8.
60 GilbertJA, JoanisseDR, ChaputJP, et al. (2011) Milk supplementation facilitates appetite control in obese women during weight loss: a randomised, single-blind, placebo-controlled trial. Br J Nutr 105, 133143.
61 JonesKW, EllerLK, ParnellJA, et al. (2013) Effect of a dairy- and calcium-rich diet on weight loss and appetite during energy restriction in overweight and obese adults: a randomized trial. Eur J Clin Nutr 67, 371376.
62 JosseAR, AtkinsonSA, TarnopolskyMA, et al. (2011) Increased consumption of dairy foods and protein during diet- and exercise-induced weight loss promotes fat mass loss and lean mass gain in overweight and obese premenopausal women. J Nutr 141, 16261634.
63 RosadoJL, GarciaOP, RonquilloD, et al. (2011) Intake of milk with added micronutrients increases the effectiveness of an energy-restricted diet to reduce body weight: a randomized controlled clinical trial in Mexican women. J Am Diet Assoc 111, 15071516.
64 ThomasDT, WidemanL & LoveladyCA (2010) Effects of calcium and resistance exercise on body composition in overweight premenopausal women. J Am Coll Nutr 29, 604611.
65 TorresMR, FrancischettiEA, GenelhuV, et al. (2010) Effect of a high-calcium energy-reduced diet on abdominal obesity and cardiometabolic risk factors in obese Brazilian subjects. Int J Clin Pract 64, 10761083.
66 TorresMR & SanjulianiAF (2013) Effects of weight loss from a high-calcium energy-reduced diet on biomarkers of inflammatory stress, fibrinolysis, and endothelial function in obese subjects. Nutrition 29, 143151.
67 Van LoanMD, KeimNL, AdamsSH, et al. (2011) Dairy foods in a moderate energy restricted diet do not enhance central fat, weight, and intra-abdominal adipose tissue losses nor reduce adipocyte size or inflammatory markers in overweight and obese adults: a controlled feeding study. J Obes 2011, 989657.
68 ZemelMB, RichardsJ, MathisS, et al. (2005) Dairy augmentation of total and central fat loss in obese subjects. Int J Obes (Lond) 29, 391397.
69 CheeWS, SuriahAR, ChanSP, et al. (2003) The effect of milk supplementation on bone mineral density in postmenopausal Chinese women in Malaysia. Osteoporos Int 14, 828834.
70 CrichtonGE, MurphyKJ, HowePR, et al. (2012) Dairy consumption and working memory performance in overweight and obese adults. Appetite 59, 3440.
71 KukuljanS, NowsonCA, BassSL, et al. (2009) Effects of a multi-component exercise program and calcium–vitamin-D3-fortified milk on bone mineral density in older men: a randomised controlled trial. Osteoporos Int 20, 12411251.
72 LauEM, WooJ, LamV, et al. (2001) Milk supplementation of the diet of postmenopausal Chinese women on a low calcium intake retards bone loss. J Bone Miner Res 16, 17041709.
73 WennersbergMH, SmedmanA, TurpeinenAM, et al. (2009) Dairy products and metabolic effects in overweight men and women: results from a 6-mo intervention study. Am J Clin Nutr 90, 960968.
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