Skip to main content
    • Aa
    • Aa
  • Access
  • Cited by 25
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Pannu, Poonam K. Calton, Emily K. and Soares, Mario J. 2016.

    Gonzalez, J T Green, B P Campbell, M D Rumbold, P L S and Stevenson, E J 2014. The influence of calcium supplementation on substrate metabolism during exercise in humans: a randomized controlled trial. European Journal of Clinical Nutrition, Vol. 68, Issue. 6, p. 712.

    Gonzalez, Javier T. and Stevenson, Emma J. 2014. Calcium co-ingestion augments postprandial glucose-dependent insulinotropic peptide1–42, glucagon-like peptide-1 and insulin concentrations in humans. European Journal of Nutrition, Vol. 53, Issue. 2, p. 375.

    Gonzalez, Javier T. Rumbold, Penny L.S. and Stevenson, Emma J. 2013. Appetite sensations and substrate metabolism at rest, during exercise, and recovery: impact of a high-calcium meal. Applied Physiology, Nutrition, and Metabolism, Vol. 38, Issue. 12, p. 1260.

    Seo, Mi Hae Kim, Mee Kyoung Park, Se Eun Rhee, Eun Jung Park, Cheol Young Lee, Won-Young Baek, Ki Hyun Song, Ki-Ho Kang, Moo Il and Oh, Ki Won 2013. The association between daily calcium intake and sarcopenia in older, non-obese Korean adults: the fourth Korea national health and nutrition examination survey (KNHANES IV) 2009. Endocrine Journal, p. 679.

    El-Merhie, Natalia Sabry, Ismail and Balbaa, Mahmoud 2012. Effect of calcium treatment on blood parameters, gonadal development and the structure of bone in immature female rats. Journal of Physiology and Biochemistry, Vol. 68, Issue. 2, p. 219.

    Gonzalez, J. T. Rumbold, P. L. S. and Stevenson, E. J. 2012. Effect of calcium intake on fat oxidation in adults: a meta-analysis of randomized, controlled trials. Obesity Reviews, Vol. 13, Issue. 10, p. 848.

    Soares, M. J. Murhadi, L. L. Kurpad, A. V. Chan She Ping-Delfos, W. L. and Piers, L. S. 2012. Mechanistic roles for calcium and vitamin D in the regulation of body weight. Obesity Reviews, Vol. 13, Issue. 7, p. 592.

    Uenishi, Hiroshi Kabuki, Toshihide Seto, Yasuyuki Serizawa, Atsushi and Nakajima, Hadjime 2012. Isolation and identification of casein-derived dipeptidyl-peptidase 4 (DPP-4)-inhibitory peptide LPQNIPPL from gouda-type cheese and its effect on plasma glucose in rats. International Dairy Journal, Vol. 22, Issue. 1, p. 24.

    Chan She Ping-Delfos, Wendy and Soares, Mario 2011. Diet induced thermogenesis, fat oxidation and food intake following sequential meals: Influence of calcium and vitamin D. Clinical Nutrition, Vol. 30, Issue. 3, p. 376.

    Dougkas, Anestis Reynolds, Christopher K. Givens, Ian D. Elwood, Peter C. and Minihane, Anne M. 2011. Associations between dairy consumption and body weight: a review of the evidence and underlying mechanisms. Nutrition Research Reviews, Vol. 24, Issue. 01, p. 72.

    Ruxton, C. H. S. 2011. Nutritional implications of obesity and dieting. Nutrition Bulletin, Vol. 36, Issue. 2, p. 199.

    Van Loan, Marta D. Keim, Nancy L. Adams, Sean H. Souza, Elaine Woodhouse, Leslie R. Thomas, Anthony Witbracht, Megan Gertz, Erik R. Piccolo, Brian Bremer, Andrew A. and Spurlock, Michael 2011. Dairy Foods in a Moderate Energy Restricted Diet Do Not Enhance Central Fat, Weight, and Intra-Abdominal Adipose Tissue Losses nor Reduce Adipocyte Size or Inflammatory Markers in Overweight and Obese Adults: A Controlled Feeding Study. Journal of Obesity, Vol. 2011, p. 1.

    Blades, Mabel and Derbyshire, Emma 2010. Does adult calcium intake influence body composition? A review. Nutrition & Food Science, Vol. 40, Issue. 5, p. 494.

    Soares, Mario J. and She-Ping-Delfos, Wendy L. Chan 2010. Postprandial Energy Metabolism in the Regulation of Body Weight: Is there a Mechanistic Role for Dietary Calcium?. Nutrients, Vol. 2, Issue. 6, p. 586.

    Soares, Mario J. Kuriyan, Rebecca and Kurpad, Anura V. 2010. Calcium and vitamin D modulate postprandial vascular function: A pilot dose–response study. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Vol. 4, Issue. 3, p. 128.

    Thomas, David T. Wideman, Laurie and Lovelady, Cheryl A. 2010. Effects of Calcium and Resistance Exercise on Body Composition in Overweight Premenopausal Women. Journal of the American College of Nutrition, Vol. 29, Issue. 6, p. 604.

    Warensjo, Eva Nolan, Deborah and Tapsell, Linda 2010.

    Heaney, Robert P and Rafferty, Karen 2009. Preponderance of the evidence: an example from the issue of calcium intake and body composition. Nutrition Reviews, Vol. 67, Issue. 1, p. 32.

    Jacobi, D. Maillot, F. and Couet, C. 2009. Calcium et régulation pondérale: aspects mécanistiques. Obésité, Vol. 4, Issue. 3-4, p. 197.


The acute effects of different sources of dietary calcium on postprandial energy metabolism

  • Nicola K. Cummings (a1), Anthony P. James (a1) and Mario J. Soares (a1)
  • DOI:
  • Published online: 01 March 2007

Dairy Ca intake has been shown to be superior to elemental Ca in increasing the loss of body fat during energy restriction. We questioned whether the mechanisms involved an increase in postprandial energy expenditure, fat oxidation and/or a greater lipolysis. The acute effects of different sources of Ca were examined in eight subjects, aged 47–66 years and BMI 27·6–36·1kg/m2, in a three-way cross-over study. Subjects were randomly provided breakfast meals either low in dairy Ca and vitamin D (LD; control), high in non-dairy Ca (calcium citrate) but low in vitamin D (HC) or high in dairy Ca and vitamin D (HD). Diet-induced thermogenesis, fat oxidation rates (FOR), carbohydrate oxidation rates (COR), insulin, glucose, ΔNEFA and glycerol were measured hourly over a 6h postprandial period. Postprandial data were calculated as a change (Δ) from the fasting value. Results showed that ΔNEFA was significantly different between meals (LD −1·50 (sem 0·26), HC −1·22 (sem 0·32), HD −0·94 (sem 0·27) mmol/l×6h; P=0·035), with a lesser suppression following both high-Ca meals. ΔFOR was significantly higher following the two high-Ca meals (LD −6·5 (sem 2·2), HC 2·93 (sem 2·34), HD 3·3 (sem 2·5) g×6;h; P=0·005), while reciprocally ΔCOR was significantly lower. ΔGlycerol was less suppressed following the high-Ca meals but statistical significance was not achieved. No differences in diet-induced thermogenesis, insulin or glucose were observed. Regardless of source, Ca intake acutely stimulated postprandial fat oxidation; and there was a lesser suppression of NEFA following these meals.

    • Send article to Kindle

      To send this article to your Kindle, first ensure is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the or variations. ‘’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      The acute effects of different sources of dietary calcium on postprandial energy metabolism
      Available formats
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      The acute effects of different sources of dietary calcium on postprandial energy metabolism
      Available formats
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      The acute effects of different sources of dietary calcium on postprandial energy metabolism
      Available formats
Corresponding author
*Corresponding author: Dr Mario J. Soares, fax +61 8 9266 2958, email
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

E Ferranini , The theoretical bases of indirect calorimetry: a review. Metabolism (1988) 37 287301.

RP Heaney , K Rafferty , MS Dowell , J Bierman , Calcium fortification systems differ in bioavailability. J Am Diet Assoc (2005) 105 807809.

R Jacobsen , JK Lorenzen , S Toubro , I Krog-Mikkelsen , A Astrup , Effect of short-term high dietary calcium intake on 24-h energy expenditure, fat oxidation, and fecal fat excretion. Int J Obes (Lond) (2005) 29 292301.

JN Mathews , DG Altman , MJ Campbell , P Royston , Analysis of serial measurements in medical research. BMJ (1990) 300 230235.

H Mehansho , RL Kanerva , GR Hudepohl , KT Smith , Calcium bioavailability and iron-calcium interaction in orange juice. J Am Coll Nutr (1989) 8 6168.

EL Melanson , WT Donahoo , F Dong , T Ida , MB Zemel , Effect of low- and high-calcium dairy-based diets on macronutrient oxidation in humans. Obes Res (2005) 13 21022112.

K Sakhaee , T Bhuket , B Adams-Huet , DS Rao , Meta-analysis of calcium bioavailability: a comparison of calcium citrate with calcium carbonate. Am J Ther (1999) 6 313321.

AL Sawaya , PL Fuss , GE Dallal , R Tsay , MA McCrory , V Young , SB Roberts , Meal palatability, substrate oxidation and blood glucose in young and older men. Physiol Behav (2001) 72 512.

AW Thorburn , Prevalence of obesity in Australia. Obes Rev (2005) 6 187189.

MB Zemel , Regulation of adiposity and obesity risk by dietary calcium: mechanisms and implications. J Am Coll Nutr (2002) 21 146S151S.

MB Zemel , J Richards , S Mathis , A Milstead , L Gebhardt , E Silva , Dairy augmentation of total and central fat loss in obese subjects. Int J Obes (Lond) (2005a) 29 391397.

MB Zemel , J Richards , A Milstead , P Campbell , Effects of calcium and dairy on body composition and weight loss in African-American adults. Obes Res (2005b) 13 12181225.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

British Journal of Nutrition
  • ISSN: 0007-1145
  • EISSN: 1475-2662
  • URL: /core/journals/british-journal-of-nutrition
Please enter your name
Please enter a valid email address
Who would you like to send this to? *