Hostname: page-component-76fb5796d-dfsvx Total loading time: 0 Render date: 2024-04-29T19:15:14.042Z Has data issue: false hasContentIssue false
  • English
  • Français

Electrophysiological Disorders in Multiple Sclerosis and Optic Neuritis

Published online by Cambridge University Press:  18 September 2015

E.A.C.M. Sanders ,
J.P.H. Reulen ,
L.A.H. Hogenhuis  and
E.A. van der Velde
E.A.C.M. Sanders
Affiliation:
Department of Neurology, University Hospital Leiden
J.P.H. Reulen
Affiliation:
Department of Medical Physics, Free University Amsterdam
Rights & Permissions [Opens in a new window]

Abstract:

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Visual evoked response (VER), auditory brainstem evoked response (ABER), somatosensory evoked response (SSER), blink reflex and electronystagmographic (ENG) investigative methods were applied to a group of 89 patients with Multiple Sclerosis (MS) and Optic Neuritis (ON). The MS patients were classified as definite (n = 31), probable (n = 31) and possible (n = 27).

The aim of this study was to determine the diagnostic value of the five electrophysiological tests in MS. VER and ABER recordings were found to reveal the highest number of asymptomatic abnormalities (33 and 31 percent respectively). The combination of VER, ABER and ENG revealed all possible electrophysiological disorders. As these tests are completely non-invasive it is proposed, that a combination of two of these three tests is useful for the detection of a second silent lesion in patients with suspected MS showing purely spinal signs (VER, ENG, ABER) and/or a history of uncomplicated ON (ABER, ENG).

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 12 , Issue 4 , November 1985 , pp. 308 - 313
Copyright
Copyright © Canadian Neurological Sciences Federation 1985

References

REFERENCES

Anton, G, Wohlwill, F (1912) Multiple nicht eitrige Encephalomyelitis und Multiple Sclerose. Zeitschrift für d ges Neurol u Psychiat 12: 31-ev.Google Scholar
Asselman, P, Chadwich, DW, Marsden, CD (1975) Visual evoked responses in the diagnosis and management of patients suspected of Multiple Sclerosis. Brain 98:261–82.CrossRefGoogle ScholarPubMed
Bartel, DR, Markand, ON, Kolar, OJ (1983) The diagnosis and classifica-tion of Multiple Sclerosis:evoked responses and spinal fluid electrophoresis. Neurology 33:611–7.CrossRefGoogle Scholar
Cala, LA, Mastaglia, FL, Black, JL (1978) Computerized tomography of brain and optic nerve in Multiple Sclerosis. Observations in 100 patients, including serial studies in 16. J Neurol Sci 36(3):411–26.CrossRefGoogle ScholarPubMed
Chiappa, KH (1980) Pattern shift visual, brainstem auditory and short latency somatosensory evoked potentials in Multiple Sclerosis. Neurology (Minneap) 30(2): 110–23.CrossRefGoogle ScholarPubMed
Chiappa, KH, Parker, SW, Shahani, BT (1985 in press) Pathoneurophysi- ology of Multiple Sclerosis. Handbook of clinical Neurology. Eds Vinken, PJ, Bruyn, GW, Klawan, HE, Koetsier, JC. Chapter 5:vol 47.Google Scholar
Cohen, MM, Lessell, S, Wole, PA (1979) A prospective study of the risk of developing Multiple Sclerosis in uncomplicated Optic Neuritis. Neurology (Minneap) 29:108–213.CrossRefGoogle ScholarPubMed
Eisen, A, Odusote, K (1980) Central and peripheral conduction times in Multiple Sclerosis, Electroenceph Clin Neurophysiol 48:253–65.CrossRefGoogle ScholarPubMed
Feasby, FE, Ebers, GC (1982) Risk of Multiple Sclerosis in isolated Optic Neuritis. The Canadian J Neurol Sci 9 (2):abstract.Google Scholar
Fog, T (1965) The topography of plaques in Multiple Sclerosis. Acta Neurol Scand Suppl 15 (41):5–161.Google Scholar
Goodwill, CJ, O’Tuama, L (1969) Electromyographic recording of the jaw reflex in Multiple Sclerosis. J Neurol Neurosurg Psychiat 32: 6–10.CrossRefGoogle ScholarPubMed
Green, JB, Walcoff, MR (1982) Evoked potentials in Multiple Sclerosis. Arch of Neurol 39:696–7.CrossRefGoogle ScholarPubMed
Gyldensted, C (1976) Computer tomography of the brain in Multiple Sclerosis. A radiological study of 110 patients with special reference to demonstration of cerebral plaques. Acta Neurol Scand 53: 386–9.CrossRefGoogle ScholarPubMed
Halliday, AM, Mcdonald, WI, Mushin, J (1972) Delayed visual evoked response in Optic Neuritis. The Lancet 983–5.Google ScholarPubMed
Halliday, AM, Mcdonald, WI, Mushin, J (1973) Visual evoked response in diagnosis of Multiple Sclerosis. Brit Med J 4:661–4.CrossRefGoogle ScholarPubMed
Hutchinson, WM (1976) Acute Optic Neuritis and the prognosis for Multiple Sclerosis. J Neurol Neurosurg Psychiat 39:283–9.CrossRefGoogle ScholarPubMed
Ikuta, F, Zimmerman, HM (1976) Distribution of plaques in seventy autopsy cases of Multiple Sclerosis in the United States. Neurology (Minneap) part 11:26–8.CrossRefGoogle Scholar
Jewett, DL, Williston, JS (1971) Auditory evoked far fields averaged from the scalp of humans. Brain 94:681–96.CrossRefGoogle ScholarPubMed
Kimura, J (1975) Electrically elicited blink reflex in diagnosis of Multiple Sclerosis. Review of 260 patients over a seven year period. Brain 98 (3):583–98.CrossRefGoogle Scholar
Kjaer, M (1983) Evoked potentials. With special reference to the diagnostic value in Multiple Sclerosis. Acta Neurol Scand 67(2):67–89.CrossRefGoogle Scholar
Kurtzke, JF (1961) On the evaluation of disability in Multiple Sclerosis. Neurology (Minneap) 11:686–94.CrossRefGoogle ScholarPubMed
Lacquaniti, F, Benna, P, Gilli, M, Troni, W, Bergamasco, B (1979) Brainstem evoked potentials and blink reflex in quiescent Multiple Sclerosis. Electroenceph Clin Neurophysiol 47:607–10.CrossRefGoogle ScholarPubMed
Lowitzsch, K, Kuhnt, U, Sackmann, CH, Maurer, K, Hope, HC, Schott, D, Thater, K (1976) Visual pattern evoked responses and blink reflexes in assessment of MS diagnosis. A clinical study of 135 Multiple Sclerosis patients. J Neurol 213:17–32.CrossRefGoogle Scholar
Mastaglia, FL, Black, JL, Collins, DWK (1979) Quantitative studies of saccadic and pursuit eye-movements in Multiple Sclerosis. Brain 102:817–34.CrossRefGoogle ScholarPubMed
Matthews, WB, Beauchamp, M, Small, DG (1974) Cervical somatosensory evoked responses in man. Naure (London) 252:230–2.CrossRefGoogle ScholarPubMed
Matthews, WB, Esiri, M (1979) Multiple Sclerosis plaques related to abnormal somatosensory evoked potentials. J Neurol Neurosurg Psychiat 42:940–2.CrossRefGoogle ScholarPubMed
Mcalpine, D, Lumsden, CE, Acheson, ED (1965) Multiple Sclerosis. A reappraisal. Livingstone, Edinburgh/London.Google Scholar
Namerow, NS, Etemadi, A (1970) The orbicularis oculi reflex in Multiple Sclerosis. Neurology (Minneap) 20:1200–3.CrossRefGoogle ScholarPubMed
Nikoskelainen, E, Frey, H, Salmi, A (1981) Prognosis of Optic Neuritis with special reference to cerebrospinal fluid immunoglobuline and measles virus antibodies. Ann Neurol 9:545–50.CrossRefGoogle ScholarPubMed
Ongerboerde Visser, BW, Goor, C (1974) Electromyographic and reflex study in idiopathic and symptomatic trigeminal neuralgias:latency of the jaw and blink reflex. Neurol Neurosurg Psychiat 37 (11): 1225–30.CrossRefGoogle Scholar
Prasher, DK, Gibson, WPR (1980) Brainstem auditory evoked potentials: a comparative study of monaural versus binaural stimulation in the detection of Multiple Sclerosis. Electroenceph Clin Neurophysiol 50:247–53.CrossRefGoogle ScholarPubMed
Reulen, JPH, Sanders, EACM, Hogenhuis, LAH (1983) Eye-movement disorders in Multiple Sclerosis and Optic Neuritis. Brain 106:121–40.CrossRefGoogle ScholarPubMed
Robinson, K, Rudge, P (1977) Abnormalities of the auditory evoked potentials in patients with Multiple Sclerosis. Brain 100:19–40.CrossRefGoogle ScholarPubMed
Robinson, K, Rudge, P (1980) The use of the auditory evoked potentials in the diagnosis of MS. J Neurol Sci 45 (2–3):235–44.CrossRefGoogle Scholar
Sandberg-Wollheim, M (1975) Optic Neuritis:studies on the cerebrospinal fluid in relation to clinical course in 61 patients. Acta Neurol Scand 52:167–78.CrossRefGoogle ScholarPubMed
Scarpalanoz, S, Tsakanikas, C, Stanboulis, E (1981) Apport de l’épreuve vestibulaire rotatoire pendulaire au diagnostic de la form spinale de la sclérose en plaques. Rev Neurol (Paris) 137 (2):147–51.Google Scholar
Schob, F (1907) Ein Beitrag zur pathologische Anatomie des Multiple Sclerose. Monatschrift fur Psych und Neurologie 22:62.Google Scholar
Shibasaki, H, Kakigi, R, Tsuji, S, Kimura, S, Kuroiwa, Y (1982) Spinal and cortical somatosensory evoked potentials in Japanese patients with Multiple Sclerosis. Neurol Sci 57:441–53.CrossRefGoogle ScholarPubMed
Small, DG, Matthews, WB, Small, M (1978) The cervical somatosensory evoked potentials (SEP) in the diagnosis of Multiple Sclerosis. J Neurol Sci 35:211–24.CrossRefGoogle ScholarPubMed
Solingen, LD, Baloh, RW, Myers, L, Ellison, G (1977) Subclinical eye-movement disorders in patients with Multiple Sclerosis. Neurology (Minneap) 27:614–9.CrossRefGoogle ScholarPubMed
Tackmann, W, Strenge, H, Barth, R, Sojka-Raytscheff, A (1980) Evaluation of various brain structures in MS with multimodality evoked potentials, blink reflex and nystagmography. J Neurol 224:33–46.CrossRefGoogle ScholarPubMed
Trojaborg, W, Petersen, E (1979) Visual and somatosensory evoked cortical potentials in MS. J Neurol Neurosurg Psychiat 42 (4):323–30.CrossRefGoogle Scholar
Vliet van, AG, Lith van, GHM (1979) Nystagmography as a diagnostic tool in Multiple Sclerosis. Doc Ophthal 46 (2):339–44.CrossRefGoogle Scholar
Yamada, T, Shivapour, E, Wilkinson, T, Kimura, J (1982) Short- and long-latency somatosensory evoked potentials in Multiple Sclerosis. Arch Neurol 39:88–94.CrossRefGoogle Scholar
Young, JR, Hall, AS, Pallis, CA, Bydder, GM, Legg, NJ, Steiner, RE(1981) Nuclear magnetic resonance imaging of the brain in Multiple Sclerosis. Lancet 11:1003–6.Google Scholar