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End-Stage Complications of Diabetic Neuropathy: Foot Ulceration

Published online by Cambridge University Press:  18 September 2015

Andrew J.M. Boulton
Andrew J.M. Boulton*
Affiliation:
The Royal Infirmary, University of Manchester, Manchester, England
*
Department of Medicine, The Royal Infirmary, The University of Manchester, Manchester, England M13 9WL
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Abstract:

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Diabetic polyneuropathy is a major complication of diabetes mellitus that frequently leads to foot ulceration. Because of economic impact of foot ulceration and subsequent amputation, major initiatives are under way in the United States and the United Kingdom to reduce their incidence by up to 50%. Although diabetic ulcers may have an ischemic and neuropathic component, the majority are neuropathic. Results from studies have shown a strong association between the neuropathy and the subsequent development of foot ulcers. However, other predisposing factors such as high foot pressures, inappropriate footwear, and other extrinsic pressure usually must be present, together with neuropathy, to cause foot ulcers. Therefore, the challenge to the physician is to identify the patient at risk and intervene so as to educate and prevent the occurrence of foot ulcers.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 21 , Issue S4 , November 1994 , pp. S18 - S22
Copyright
Copyright © Canadian Neurological Sciences Federation 1994

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