Hostname: page-component-76fb5796d-x4r87 Total loading time: 0 Render date: 2024-04-28T17:24:24.051Z Has data issue: false hasContentIssue false

Outcomes after Epilepsy Surgery

Published online by Cambridge University Press:  02 December 2014

José F. Téllez-Zenteno*
Affiliation:
Division of Neurology, Department of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan
Lizbeth Hernandez-Ronquillo
Affiliation:
Division of Neurology, Department of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan
Jorge Burneo
Affiliation:
Epilepsy Program, Departments of Clinical Neurological Sciences, Schulich School of Medicine, Western University, London, Ontario, Canada
*
Department of Medicine, Division of Neurology, Royal University Hospital, Saskatoon, Saskatchewan, S7N 0W8, Canada. Email: jftellez@yahoo.com
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Epilepsy surgery is a highly effective and durable treatment for specific types of drug resistant epilepsy such as temporal lobe epilepsy. assessment of outcomes is essential in epilepsy surgery, which is an irreversible intervention for a chronic condition. Excellent short-term results of resective epilepsy surgery have been established. In the last years more information regarding long term outcomes have been published. This article reviews the best available evidence about the best measures to assess outcomes and the most important evidence. The outcomes reviewed in this article are the following: seizure outcome, social and psychiatric outcomes, complications and mortality.

Résumé

RÉSUMÉ

La chirurgie de l'épilepsie est un traitement très efficace et durable de certains types bien spécifiques d'épilepsies pharmacorésistantes telle l'épilepsie du lobe temporal. L'évaluation des résultats est essentiel dans la chirurgie de l'épilepsie, une intervention irréversible effectuée pour traiter une maladie chronique. Les excellents résultats à court terme de la résection chirurgicale sont bien connus. au cours des dernières années, des informations supplémentaires sur les résultats à long terme ont été publiés. Cet article revoit les meilleures données disponibles concernant les meilleures méthodes d'évaluation des résultats et les données les plus importantes. Nous revoyons les résultats suivants : l'effet sur les crises, l'impact social et psychiatrique, les complications et la mortalité.

Type
Research Article
Copyright
Copyright © The Canadian Journal of Neurological 2012

References

1. Wiebe, S, Blume, WT, Girvin, JP, Eliasziw, M. A randomized, controlled trial of surgery for temporal-lobe epilepsy. N Engl J Med. 2001;345:3118.CrossRefGoogle ScholarPubMed
2. Engel, J Jr., Wiebe, S, French, J, et al. Practice parameter: temporal lobe and localized neocortical resections for epilepsy: report of the Quality Standards Subcommittee of the American Academy of Neurology, in association with the American Epilepsy Society and the American Association of Neurological Surgeons. Neurology. 2003;60:53847.Google Scholar
3. Wiebe, S. Outcome measures in intractable epilepsy. Adv Neurol. 2006;97:115.Google Scholar
4. Engel, J Jr.,Wiebe, S, French, J, et al. Practice parameter: temporal lobe and localized neocortical resections for epilepsy. Epilepsia. 2003;44:74151.Google Scholar
5. Tellez-Zenteno, JF, Dhar, R, Wiebe, S. Long-term seizure outcomes following epilepsy surgery: a systematic review and meta-analysis. Brain. 2005;128:118898.Google Scholar
6. Devinsky, O. The Meaning of Quality of Life to Patients with Epilepsy. Epilepsy Behav. 2000;1:S18S20.CrossRefGoogle ScholarPubMed
7. Leone, MA, Beghi, E, Righini, C, Apolone, G, Mosconi, P. Epilepsy and quality of life in adults: a review of instruments. Epilepsy Res. 2005;66:2344.Google Scholar
8. Seiam, AH, Dhaliwal, H, Wiebe, S. Determinants of quality of life after epilepsy surgery: systematic review and evidence summary. Epilepsy Behav. 2011;21:4415.Google Scholar
9. Schmidt, D, Loscher, W. How effective is surgery to cure seizures in drug-resistant temporal lobe epilepsy? Epilepsy Res. 2003;56:8591.Google Scholar
10. Tellez-Zenteno, JF, Dhar, R, Hernandez-Ronquillo, L, Wiebe, S. Long-term outcomes in epilepsy surgery: antiepileptic drugs, mortality, cognitive and psychosocial aspects. Brain. 2007;130:33445.Google Scholar
11. Berg, AT, Vickrey, BG, Langfitt, JT, et al. Reduction of AEDs in postsurgical patients who attain remission. Epilepsia. 2006;47: 6471.Google Scholar
12. Tellez-Zenteno, JF, Ronquillo, LH, Jette, N, et al. Discontinuation of antiepileptic drugs after successful epilepsy surgery. A Canadian survey. Epilepsy Res. 2012.Google Scholar
13. Schiller, Y, Cascino, GD, So, EL, Marsh, WR. Discontinuation of antiepileptic drugs after successful epilepsy surgery. Neurology. 2000;54:3469.Google Scholar
14. Rathore, C, Panda, S, Sarma, PS, Radhakrishnan, K. How safe is it to withdraw antiepileptic drugs following successful surgery for mesial temporal lobe epilepsy? Epilepsia. 2011;52:62735.Google Scholar
15. Tomson, T. Mortality in epilepsy. J Neurol. 2000;247:1521.Google Scholar
16. Klenerman, P, Sander, JW, Shorvon, SD. Mortality in patients with epilepsy: a study of patients in long term residential care. J Neurol Neurosurg Psychiatry. 1993;56:14952.Google Scholar
17. Zielinski, JJ. Epilepsy and mortality rate and cause of death. Epilepsia. 1974;15:191201.Google Scholar
18. Salanova, V, Markand, O, Worth, R. Temporal lobe epilepsy surgery: outcome, complications, and late mortality rate in 215 patients. Epilepsia. 2002;43:1704.Google Scholar
19. Stavem, K, Guldvog, B. Long-term survival after epilepsy surgery compared with matched epilepsy controls and the general population. Epilepsy Res. 2005;63:6775.Google Scholar
20. Guldvog, B, Loyning, Y, Hauglie-Hanssen, E, Flood, S, Bjornaes, H. Surgical versus medical treatment for epilepsy. I. Outcome related to survival, seizures, and neurologic deficit. Epilepsia. 1991;32:37588.Google Scholar
21. Vickrey, BG, Hays, RD, Rausch, R, et al. Outcomes in 248 patients who had diagnostic evaluations for epilepsy surgery. Lancet. 1995;346:14459.Google Scholar
22. Hennessy, MJ, Langan, Y, Elwes, RD, Binnie, CD, Polkey, CE, Nashef, L. A study of mortality after temporal lobe epilepsy surgery. Neurology. 1999;53:127683.Google Scholar
23. Seymour, N, Granbichler, CA, Polkey, CE, Nashef, L. Mortality after temporal lobe epilepsy surgery. Epilepsia. 2012;53:26771.CrossRefGoogle ScholarPubMed
24. Bell, GS, Sinha, S, Tisi, J, et al. Premature mortality in refractory partial epilepsy: does surgical treatment make a difference? J Neurol Neurosurg Psychiatry. 2010;81:7168.Google Scholar
25. Elger, CE, Helmstaedter, C, Kurthen, M. Chronic epilepsy and cognition. Lancet Neurol. 2004;3:66372.Google Scholar
26. Sherman, EM, Wiebe, S, Fay-McClymont, TB, et al. Neuropsychological outcomes after epilepsy surgery: systematic review and pooled estimates. Epilepsia. 2011;52:85769.Google Scholar
27. Helmstaedter, C, Kurthen, M, Lux, S, Reuber, M, Elger, CE. Chronic epilepsy and cognition: a longitudinal study in temporal lobe epilepsy. Ann Neurol. 2003;54:42532.Google Scholar
28. Hamiwka, L, Macrodimitris, S, Tellez-Zenteno, JF, et al. Social outcomes after temporal or extratemporal epilepsy surgery: a systematic review. Epilepsia. 2011;52:8709.Google Scholar
29. Macrodimitris, S, Sherman, EM, Forde, S, et al. Psychiatric outcomes of epilepsy surgery: a systematic review. Epilepsia. 2011;52:88090.Google Scholar
30. Hader, w. Complications of epilepsy surgery. In: Jette, N, ed. A Literature Review of the Natural History, Epidemiology, and surgical outcomes of epilepsy, with a focus on Localization-Related Epilepsy RAND/UCLA CASES Study Literature Review; 2009:94104.Google Scholar