Hostname: page-component-848d4c4894-p2v8j Total loading time: 0.001 Render date: 2024-05-17T00:49:18.524Z Has data issue: false hasContentIssue false
  • English
  • Français

Pituitary Adenomas in Childhood and Adolescence

Published online by Cambridge University Press:  18 September 2015

G. Maira  and
C. Anile
G. Maira*
Affiliation:
Institute of Neurosurgery, Catholic University, Rome, Italy
C. Anile
Affiliation:
Institute of Neurosurgery, Catholic University, Rome, Italy
*
Istituto di Neurochirurgia, Policlinico Gemelli, Largo Gemelli 8, 00168 Roma, Italia
Rights & Permissions [Opens in a new window]

Abstract:

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Pituitary adenomas are considered rare tumors in the pediatric age group. The natural history in this age group is not well known, although many authors have suggested that pituitary adenomas in children tend to be extrasellar and invasive and that a subfrontal approach is mandatory in the majority. Our patients were part of a surgical series of 356 adenomas of all ages. We have divided these cases into three groups: the first consists of patients operated on before the age of 21 years (52 cases, 15%); the second, patients treated after the age of 20 but in whom the clinical history started before 21 years (52 cases, 15%); the third, patients with surgery and symptoms after 20 years (252 cases, 70%). Transsphenoidal removal of the adenomas was the initial procedure in all but one of these cases; a few required a second intracranial operation. In our series, pituitary adenomas in children were not more invasive than in other age groups.

Type
Special Supplement - Secreting Pituitary Adenomas
Information
Canadian Journal of Neurological Sciences , Volume 17 , Issue 1 , February 1990 , pp. 83 - 87
Copyright
Copyright © Canadian Neurological Sciences Federation 1990

References

REFERENCES

1.Costin, G. Endocrine disorders associated with tumors of the pituitary and hypothalamus. Pediatr Clin North Am 1979; 26: 15–31.CrossRefGoogle ScholarPubMed
2.Dastur, DK, Lalitha, US. Pathological analysis of intracranial space-occupying lesions in 1,000 cases including children. Pituitary adenomas, developmental tumors, parasitic and developmental cysts. J Neurol Sci 1972; 15: 397–427.CrossRefGoogle Scholar
3.David, M, Bernard-Weil, E, Pradat, P. Adénomes hypophisaires de l’'enfant. Revue Neurol 1962; 106: 334–336.Google Scholar
4.Fraioli, B, Ferrante, L, Celli, P. Pituitary adenomas with onset during puberty. J Neurosurg 1983; 59: 590–595.CrossRefGoogle ScholarPubMed
5.Gaini, SM, Giovannelli, M, Forni, C, et al. Pituitary adenomas in infancy and childhood. In: Villani, R, Giovannelli, M, Gaini, SM, eds. Modern Problems in Paediatrics. Basel: Karger 1977; 220–225.Google Scholar
6.Koos, WT, Miller, MH. Intracranial tumors of infants and children. Stuttgart: G. Thieme Verlag 1971; 213–220.Google Scholar
7.Laws, ER, Scheithauer, BW, Groover, RV. Pituitary adenomas in childhood and adolescence. Prog Exp Tumor Res. Basel: Karger 1987; 359–361.Google Scholar
8.Lucas, C, Guibout, M, Jaquet, P, et al. Aspects diagnostiques et évolutifs de l’adénome à prolactine chez l’enfant. Arch Fr Pediatr 1980; 37: 79–86.Google Scholar
9.Ludecke, DK, Herrmann, HD, Schulte, FJ. Special problems with neurosurgical treatment of hormone-secreting pituitary adenomas in children. Prog Exp Tumor Res. Basel: Karger 1987: 362–370.Google Scholar
10.Odom, GL, Davis, CH, Woodhall, B. Brain tumors in children. Clinical analysis of 164 cases. Pediatrics 1956; 18: 856–870.Google Scholar
11.Richmond, IL, Wilson, CB. Pituitary adenomas in childhood and adolescence. J Neurosurg 1978; 49: 163–168.CrossRefGoogle ScholarPubMed
12.Barrio, R, Roger, M, Chaussain, J-L, et al. Les adénomes hypophysaires à prolactine de l’enfant et de l’adolescent. Arch Franc Pediat 1979; 36, 8: 785–793.Google Scholar
13.Martins, A, Hayes, GJ, Kempe, LG. Invasive pituitary adenomas. J Neurosurg 1965; 22: 268–276.CrossRefGoogle ScholarPubMed
14.Ortiz-Suarez, H, Erickson, DL. Pituitary adenomas of adolescents. J Neurosurg 1975; 43: 437–439.CrossRefGoogle ScholarPubMed
15.Weinberger, LM, Adler, FH, Grant, FC. Primary pituitary adenoma and the syndrome of the cavernous sinus. A clinical and anatomic study. Arch Ophthalmol 1940; 24: 1197–1236.CrossRefGoogle Scholar
16.Hardy, J. Transsphenoidal microsurgical removal fo pituitary microadenoma. In: Krayenbuhl, H, Maspes, PE and Sweet, WH, eds. Progress in Neurological Surgery. Basel: Karger 1975; 200–216.Google Scholar
17.Wilson, CB. A decade of pituitary microsurgery. The Herbert Olivecrona lecture. J Neurosurg 1984; 61: 814–833.CrossRefGoogle ScholarPubMed
18.Hardy, J, Vezina, JL. Transsphenoidal neurosurgery of intracranial neoplasm. In: Thompson, RA and Greene, JR, eds. Advances in Neurology. New York: Raven Press 1976; 261–264.Google Scholar
19.Barbarino, A, De Marinis, L, Maira, G, et al. Serum prolactin response to thyrotropin-releasing hormone and metoclopramide in patients with prolactin-secreting tumors before and after transsphenoidal surgery. J Clin Endocrinol Metab 1978; 47: 1148–1151.Google ScholarPubMed
20.De Marinis, L, Mancini, A, Maira, G, et al. Postoperative evaluation of dopaminergic tone in prolactinoma patients. 11. Plasma thyrotropin response to metoclopramide. J Clin Endocrinol Metab 1984; 58: 405–409.Google Scholar
21.Maira, G, Di Rocco, C, Borrelli, P, et al. Pituitary microadenomas in children: a cause of growth failure. J Microsurg 1980; 1: 276–287.CrossRefGoogle ScholarPubMed
22.Wilson, CB, Dempsey, LC. Transsphenoidal microsurgical removal of 250 pituitary adenomas. J Neurosurg 1978; 48: 13–22.Google ScholarPubMed
23.Di Rocco, C, Maira, G, Borrelli, P. Pituitary microadenomas in children. Child’s Brain 1982; 9: 165–178.Google ScholarPubMed