Skip to main content
    • Aa
    • Aa

Hospitalization of paediatric patients for methicillin-resistant Staphylococcus aureus skin and soft-tissue infection, 1998–2006

  • K. D. SIRCAR (a1), E. BANCROFT (a2), D. M. NGUYEN (a1) and L. MASCOLA (a2)

Hospital discharge reports have provided data for studies of methicillin-resistant Staphylococcus aureus (MRSA) skin and soft-tissue infection (SSTI) studies. This analysis determined the sensitivity and positive predictive value of International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) code combinations to calculate hospitalization incidence rates, representativeness of a set of three ICD-9-CM codes to define MRSA SSTI, and hospitalization incidence rate trends for paediatric MRSA SSTIs in Los Angeles County (LAC). Using 133 cases from 31 hospitals, we found that the set of three ICD-9-CM codes used to define laboratory-confirmed cases had one of the highest positive predictive values (49%). There was no difference in age and race between those categorized using three codes vs. other code combinations. A dramatic increase in paediatric MRSA SSTI cases occurred in LAC during 1998–2006. We conclude that this combination of codes may be used to determine the rise of MRSA SSTIs in paediatric populations.

Corresponding author
*Author for correspondence: K. D. Sircar, Ph.D., M.P.H., 313 N. Figueroa Street, Room 212, Los Angeles, CA90012. (Email:
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

2.E Klein , DL Smith , R Laxminarayan . Hospitalizations and deaths caused by methicillin-resistant Staphylococcus aureus, United States, 1999–2005. Emerging Infectious Diseases 2007; 13: 18401846.

3.National Center for Health Statistics. International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) ( Accessed 3 May 2009.

4.MB Hasty , Cutaneous community-associated methicillin-resistant Staphylococcus aureus among all skin and soft-tissue infections in two geographically distant pediatric emergency departments. Academic Emergency Medicine 2007; 14: 3540.

5.PS Romano , DH Mark . Bias in the coding of hospital discharge data and its implications for quality assessment. Medical Care 1994; 32: 8190.

6.J Green , N Wintfeld . How accurate are hospital discharge data for evaluating effectiveness of care? Medical Care 1993; 31: 719731.

7.SF Marshall , Validating California teachers study self-reports of recent hospitalization: comparison with California hospital discharge data. American Journal of Epidemiology 2003; 158: 10121020.

8.MJ Kuehnert , Methicillin-resistant-Staphylococcus aureus hospitalizations, United States. Emerging Infectious Diseases 2005; 11: 868872.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *