Skip to main content
×
Home
    • Aa
    • Aa

Invasive group A streptococcal disease in children in Queensland

  • B. D. WHITEHEAD (a1), H. V. SMITH (a2) and C. NOURSE (a1) (a3)
Abstract
SUMMARY

The epidemiology and clinical features of invasive group A streptococcal (iGAS) disease in Queensland children was investigated in response to anecdotal evidence of an increase in frequency and severity of this condition. A retrospective review of clinical records of all cases of iGAS disease notified to Queensland Health aged 0–18 years during a 5-year period was conducted. The annualized incidence of iGAS was 3·5/100 000 for the total population aged 0–18 and 13·2/100 000 for the Indigenous population of similar age. The annualized incidence was highest in Indigenous infants but no increase in frequency or severity of iGAS infections was observed. Findings included an increased prevalence in Indigenous children particularly in those aged <1 year, a significant male preponderance, lack of seasonal variation and an association with blunt trauma. Further studies are required to confirm and investigate these findings and to define specific risk factors in high-risk groups.

Copyright
Corresponding author
*Author for correspondence: Dr B. Whitehead, University of Queensland, Mater Health Services, Raymond Terrace, South Brisbane, QLD4101, Australia. (Email: Benwhitehead10@yahoo.com.au)
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1.TL Lamagni , Epidemiology of severe Streptococcus pyogenes disease in Europe. Journal of Clinical Microbiology 2008; 46: 23592367.

2.J Carapetis , Increasing severity of invasive group A streptococcal disease in Australia: clinical and molecular epidemiological features and identification of a new virulent M-nontypeable clone. Clinical Infectious Diseases 1995; 21: 12201227.

3.AC Steer , MH Danchin , JR Carapetis . Group A streptococcal infections in children. Journal of Paediatric Child Health 2007; 43: 203213.

4.HD Davies , Invasive group A streptococcal infections in Ontario, Canada. Ontario Group A Streptococcal Study Group. New England Journal of Medicine 1996; 335: 547554.

5.KA O'Grady , The epidemiology of invasive group A streptococcal disease in Victoria, Australia. Medical Journal of Australia 2007; 186: 565569.

6.S Rogers , Strain prevalence, rather than innate virulence potential, is the major factor responsible for an increase in serious group A streptococcus infections. Journal of Infectious Diseases 2007; 195: 16251633.

7.KL O'Brien , Epidemiology of invasive group A streptococcus disease in the United States, 1995–1999. Clinical Infectious Diseases 2002; 35: 268276.

8.LB Givner . Invasive disease due to group A beta-hemolytic streptococci: continued occurrence in children in North Carolina. Southern Medical Journal 1998; 91: 333337.

9.R Ben-Abraham , Invasive group A streptococcal infections in a large tertiary center: epidemiology, characteristics and outcome. Infection 2002; 30: 8185.

10.GJ Tyrrell , Invasive group A streptococcal disease in Alberta, Canada (2000 to 2002). Journal of Clinical Microbiology 2005; 43: 16781683.

11.TL Lamagni , Severe Streptococcus pyogenes infections, United Kingdom, 2003–2004. Emerging Infectious Diseases 2008; 14: 202209.


13.JR Carapetis , Clinical and epidemiological features of group A streptococcal bacteraemia in a region with hyperendemic superficial streptococcal infection. Epidemiology and Infection 1999; 122: 5965.

15.RF Breiman , Defining the group A streptococcal toxic shock syndrome. Rationale and consensus definition. The Working Group on Severe Streptococcal Infections. Journal of the American Medical Association 1993; 269: 390391.

16.J Stanley , High-resolution genotyping elucidates the epidemiology of group A streptococcus outbreaks. Journal of Infectious Diseases 1996; 174: 500506.

17.KB Laupland , Population-based surveillance of invasive pyogenic streptococcal infection in a large Canadian region. Clinical Microbiology and Infection 2006; 12: 224230.

18.AE Moses , Invasive group a streptococcal infections, Israel. Emerging Infectious Diseases 2002; 8: 421426.

19.KB Laupland , Invasive group A streptococcal disease in children and association with varicella-zoster virus infection. Ontario Group A Streptococcal Study Group. Pediatrics 2000; 105: E60.

20.RE O'Loughlin , The epidemiology of invasive group A streptococcal infection and potential vaccine implications: United States, 2000–2004. Clinical Infectious Diseases 2007; 45: 853862.

21.BA Duff , Invasive group A streptococcal disease in children. Clinical Pediatrics 1999; 38: 417423.

23.American Academy of Pediatrics. Committee on Infectious Diseases. Severe invasive group A streptococcal infections: a subject review. Pediatrics 1998; 101: 136140.

24.AM Burnett , JB Domachowske . Therapeutic considerations for children with invasive group a streptococcal infections: a case series report and review of the literature. Clinical Pediatrics 2007; 46: 550555.

25.ZD Mulla , PE Leaverton , ST Wiersma . Invasive group A streptococcal infections in Florida. Southern Medical Journal 2003; 96: 968973.

26.GJ Tyrrell , Varicella-associated invasive group A streptococcal disease in Alberta, Canada – 2000–2002. Clinical Infectious Diseases 2005; 40: 10551057.

27.E Ciftci , Invasive group A streptococcal infections in children: an emerging infectious disease in Turkey. Annals of Tropical Paediatrics 2004; 24: 365366.

28.RA Patel , HJ Binns , ST Shulman . Reduction in pediatric hospitalizations for varicella-related invasive group A streptococcal infections in the varicella vaccine era. Journal of Pediatrics 2004; 144: 6874.

29.ZB Nuwayhid , DM Aronoff , ZD Mulla . Blunt trauma as a risk factor for group A streptococcal necrotizing fasciitis. Annals of Epidemiology 2007; 17: 878881.

30.AE Bryant , Group A streptococcal myonecrosis: increased vimentin expression after skeletal-muscle injury mediates the binding of Streptococcus pyogenes. Journal of Infectious Diseases 2006; 193: 16851692.

31.JM Musser , Streptococcus pyogenes causing toxic-shock-like syndrome and other invasive diseases: clonal diversity and pyrogenic exotoxin expression. Proceedings of the National Academy of Sciences USA 1991; 88: 26682672.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords: