Skip to main content
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 37
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Makranz, Chen Qutteineh, Hiba Bin, Hanna Lustig, Yaniv Gomori, John Moshe Honig, Asaf Bayya, Abed El-Raouf Moses, Allon E. Ben-Hur, Tamir Averbuch, Diana Eichel, Roni and Nir-Paz, Ran 2016. Sandfly virus seroconversion associated with neurologic presentation. Neurology - Neuroimmunology Neuroinflammation, Vol. 3, Issue. 1, p. e184.

    Lvov, Dimitry Konstantinovich Shchelkanov, Mikhail Yurievich Alkhovsky, Sergey Vladimirovich and Deryabin, Petr Grigorievich 2015. Zoonotic Viruses in Northern Eurasia.

    Ergunay, Koray 2014. Emerging Infectious Diseases.

    Ergunay, Koray Kasap, Ozge Erisoz Orsten, Serra Oter, Kerem Gunay, Filiz Yoldar, Ayse Zeynep Akkutay Dincer, Ender Alten, Bulent and Ozkul, Aykut 2014. Phlebovirus and Leishmania detection in sandflies from eastern Thrace and northern Cyprus. Parasites & Vectors, Vol. 7, Issue. 1,

    Horne, Kate and Vanlandingham, Dana 2014. Bunyavirus-Vector Interactions. Viruses, Vol. 6, Issue. 11, p. 4373.

    Alkan, Cigdem Bichaud, Laurence de Lamballerie, Xavier Alten, Bulent Gould, Ernest A. and Charrel, Rémi N. 2013. Sandfly-borne phleboviruses of Eurasia and Africa: Epidemiology, genetic diversity, geographic range, control measures. Antiviral Research, Vol. 100, Issue. 1, p. 54.

    Anagnostou, Vassiliki and Papa, Anna 2013. Seroprevalence of Toscana virus among residents of Aegean Sea islands, Greece. Travel Medicine and Infectious Disease, Vol. 11, Issue. 2, p. 98.

    Anagnostou, V. and Papa, A. 2013. Prevalence of antibodies to phleboviruses within the sand fly fever Naples virus species in humans, northern Greece. Clinical Microbiology and Infection, Vol. 19, Issue. 6, p. 566.

    MAROLI, M. FELICIANGELI, M. D. BICHAUD, L. CHARREL, R. N. and GRADONI, L. 2013. Phlebotomine sandflies and the spreading of leishmaniases and other diseases of public health concern. Medical and Veterinary Entomology, Vol. 27, Issue. 2, p. 123.

    Amodio, Emanuele Cusi, Maria Grazia Valenti, Rosalia Maria Valentini, Melissa Mammina, Caterina Gori-Savellini, Gianni Vitale, Francesco Romano, Nino Goedert, James J. and Calamusa, Giuseppe 2012. Immunoglobulin M seropositivity for Toscana virus in a random population sample in Sicily. International Journal of Infectious Diseases, Vol. 16, Issue. 8, p. e633.

    Calamusa, Giuseppe Valenti, Rosalia Maria Vitale, Francesco Mammina, Caterina Romano, Nino Goedert, James Jerome Gori-Savellini, Gianni Cusi, Maria Grazia and Amodio, Emanuele 2012. Seroprevalence of and risk factors for Toscana and Sicilian virus infection in a sample population of Sicily (Italy). Journal of Infection, Vol. 64, Issue. 2, p. 212.

    Ergunay, K. Aydogan, S. Ilhami Ozcebe, O. Cilek, E. E. Hacioglu, S. Karakaya, J. Ozkul, A. and Us, D. 2012. Toscana Virus (TOSV) exposure is confirmed in blood donors from Central, North and South/Southeast Anatolia, Turkey. Zoonoses and Public Health, Vol. 59, Issue. 2, p. 148.

    Punda-Polić, V. Jerončić, A. Mohar, B. and Kraljevićc, K. Šiško 2012. Prevalence of Toscana virus antibodies in residents of Croatia. Clinical Microbiology and Infection, Vol. 18, Issue. 6, p. E200.

    Cusi, Maria Grazia and Savellini, Gianni Gori 2011. Diagnostic tools for Toscana virus infection. Expert Review of Anti-infective Therapy, Vol. 9, Issue. 7, p. 799.

    Ergünay, Koray Litzba, Nadine Lo, Modou Moustapha Aydoğan, Sibel Saygan, Mehmet B. Us, Dürdal Weidmann, Manfred and Niedrig, Matthias 2011. Performance of Various Commercial Assays for the Detection of Toscana Virus Antibodies. Vector-Borne and Zoonotic Diseases, Vol. 11, Issue. 6, p. 781.

    Ergünay, K. Saygan, M.B. Aydogan, S. Lo, M.M. Weidmann, M. Dilcher, M. şener, B. Hasçelik, G. Pinar, A. and Us, D. 2011. Sandfly fever virus activity in central/northern Anatolia, Turkey: first report of Toscana virus infections. Clinical Microbiology and Infection, Vol. 17, Issue. 4, p. 575.

    Kocak Tufan, Zeliha Weidmann, Manfred Bulut, Cemal Kinikli, Sami Hufert, Frank T. Dobler, Gerhard and Demiroz, Ali Pekcan 2011. Clinical and laboratory findings of a sandfly fever Turkey Virus outbreak in Ankara. Journal of Infection, Vol. 63, Issue. 5, p. 375.

    Navarro-Marí, José María Palop-Borrás, Begoña Pérez-Ruiz, Mercedes and Sanbonmatsu-Gámez, Sara 2011. Serosurvey Study of Toscana Virus in Domestic Animals, Granada, Spain. Vector-Borne and Zoonotic Diseases, Vol. 11, Issue. 5, p. 583.

    Ranaldi, Renzo Goteri, Gaia Biagetti, Simona Cusi, Maria Grazia and Rossini, Simonetta 2011. Histological description of the lymphadenopathy related to Toscana virus infection. Report of a case. Pathology - Research and Practice, Vol. 207, Issue. 3, p. 197.

    Serata, Daniele Rapinesi, Chiara Del Casale, Antonio Simonetti, Alessio Mazzarini, Lorenzo Ambrosi, Elisa Kotzalidis, Giorgio D. Fensore, Claudio Girardi, Paolo and Tatarelli, Roberto 2011. Personality Changes After Toscana Virus (TOSV) Encephalitis in a 49-Year-Old Man: A Case Report. International Journal of Neuroscience, Vol. 121, Issue. 3, p. 165.


High prevalence rates of antibody to three sandfly fever viruses (Sicilian, Naples and Toscana) among Cypriots

  • R. Eitrem (a1) (a2), M. Stylianou (a3) and B. Niklasson (a1) (a4)
  • DOI:
  • Published online: 01 May 2009

Neutralizing antibodies to sandfly fever Naples, sandfly fever Sicilian and Toscana viruses were investigated among 479 sera collected from a normal human population in Cyprus. Antibody prevalence rates of 57%, 32% and 20% were found to Naples, Sicilian and Toscana viruses, respectively. The observed frequency of dual and triple infections was higher than would be expected with a random chance of infection. Antibody prevalence rates were similar for men and women for all three viruses tested, but one of two study sites had significantly higher antibody prevalence to Naples and Sicilian viruses than the other. Individuals with antibodies to both Naples and Toscana viruses had higher antibody levels to Naples virus than those with antibodies to Naples virus only. If the antibody prevalence rates found in this study reflect a history of clinical disease as described in the literature, sandfly fever poses a significant public health problem in Cyprus.

Corresponding author
*Rickard Eitrem, MD. Department of Infectious Disease Control. Central Hospital. S-371 85 Karlskrona, Sweden
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

9.E Earley , PH Peralta , KM Johnson . A plaque neutralization method for arboviruses. Proc Soc Exp Biol Med 1967; 125: 741–7.

12.R Eitrem , B Niklasson , O Weiland . Sandfly fever among Swedish Tourists. Scand J Infect Dis. 1991; 23: 451–7.

13.AB Sabin , CB Philip , JR Paul . Phlebotomus (Pappataci or sandfly) fever, a disease of miilitary importance. Summary of existing knowledge and preliminary report of original investigations. JAMA 1944; 125: 603–6, 693–9.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *