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Multiple outbreaks of a novel norovirus GII.4 linked to an infected post-symptomatic food handler

  • C. N. THORNLEY (a1), J. HEWITT (a2), L. PERUMAL (a1), S. M. VAN GESSEL (a1), J. WONG (a1), S. A. DAVID (a1), J. P. RAPANA (a1), S. LI (a1), J. C. MARSHALL (a3) and G. E. GREENING (a2)...
Summary
SUMMARY

Multiple norovirus outbreaks following catered events in Auckland, New Zealand, in September 2010 were linked to the same catering company and investigated. Retrospective cohort studies were undertaken with attendees of two events: 38 (24·1%) of 158 surveyed attendees developed norovirus-compatible illness. Attendees were at increased risk of illness if they had consumed food that had received manual preparation following cooking or that had been prepared within 45 h following end of symptoms in a food handler with prior gastroenteritis. All food handlers were tested for norovirus. A recombinant norovirus GII.e/GII.4 was detected in specimens from event attendees and the convalescent food handler. All catering company staff were tested; no asymptomatic norovirus carriers were detected. This investigation improved the characterization of norovirus risk from post-symptomatic food handlers by narrowing the potential source of transmission to one individual. Food handlers with gastroenteritis should be excluded from the workplace for 45 h following resolution of symptoms.

Copyright
Corresponding author
*Author for correspondence: Dr C. N. Thornley, Ministry for Primary Industries, Pastoral House, 25 The Terrace, PO Box 2526, Wellington 6140, New Zealand. (Email: craig.thornley@mpi.govt.nz)
References
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1.de Wit MA, et al. Sensor, a population-based cohort study on gastroenteritis in the Netherlands: incidence and etiology. American Journal of Epidemiology 2001; 154: 666674.
2.Phillips G, et al. Community incidence of norovirus-associated infectious intestinal disease in England: improved estimates using viral load for norovirus diagnosis. American Journal of Epidemiology 2010; 171: 10141022.
3.Scallan E, et al. Foodborne illness acquired in the United States – major pathogens. Emerging Infectious Diseases 2011; 17: 715.
4.Becker KM, et al. Transmission of Norwalk virus during football game. New England Journal of Medicine 2000; 343: 12231227.
5.Kuusi M, et al. A prolonged outbreak of Norwalk-like calicivirus (NLV) gastroenteritis in a rehabilitation centre due to environmental contamination. Epidemiology and Infection 2002; 129: 133138.
6.Jones EL, et al. Role of fomite contamination during an outbreak of norovirus on houseboats. International Journal of Environmental Health Research 2007; 17: 123131.
7.Evans MR, et al. An outbreak of viral gastroenteritis following environmental contamination at a concert hall. Epidemiology and Infection 2002; 129: 355360.
8.Anderson AD, et al. Multistate outbreak of Norwalk-like virus gastroenteritis associated with a common caterer. American Journal of Epidemiology 2001; 154: 10131019.
9.Hewitt J, et al. Gastroenteritis outbreak caused by waterborne norovirus at a New Zealand ski resort. Applied and Environmental Microbiology 2007; 73: 78537857.
10.Marks PJ, et al. Evidence for airborne transmission of Norwalk-like virus (NLV) in a hotel restaurant. Epidemiology and Infection 2000; 124: 481487.
11.Simmons G, et al. Raw oyster consumption and outbreaks of viral gastroenteritis in New Zealand: evidence for risk to the public's health. Australian and New Zealand Journal of Public Health 2001; 25: 234240.
12.Falkenhorst G, et al. Imported frozen raspberries cause a series of norovirus outbreaks in Denmark, 2005. Eurosurveillance 2005; 10: E050922.2.
13.Widdowson M, et al. Norovirus and foodborne disease, United States, 1991–2000. Emerging Infectious Diseases 2005; 11: 95102.
14.Moe CL. Preventing norovirus transmission: how should we handle food handlers? Clinical Infectious Diseases 2009; 48: 3840.
15.Food Standards Agency. Food handlers: fitness to work. Regulatory guidance and best practice advice for food business operators. London: Food Standards Agency, 2009, p. 9.
16.Communicable Diseases Network Australia. Guidelines for the public health management of gastroenteritis outbreaks due to norovirus or suspected viral agents in Australia. Canberra: Commonwealth of Australia, 2010, p. 33.
17.Centers for Disease Control and Prevention. Updated norovirus outbreak management and disease prevention guidelines. Morbidity and Mortality Weekly Report: Recommendations and Reports 2011; 60: 115.
18.Atmar RL, et al. Norwalk virus shedding after experimental human infection. Emerging Infectious Diseases 2008; 14: 15531557.
19.Aoki Y, et al. Duration of norovirus excretion and the longitudinal course of viral load in norovirus-infected elderly patients. Journal of Hospital Infection 2010; 75: 4246.
20.Karim MR, Pontius FW, LeChevallier MW. Detection of noroviruses in water–summary of an international workshop. Journal of Infectious Diseases 2004; 189: 2128.
21.Friedman DS, et al. An outbreak of norovirus gastroenteritis associated with wedding cakes. Epidemiology and Infection 2005; 133: 10571063.
22.Ozawa K, et al. Norovirus infections in symptomatic and asymptomatic food handlers in Japan. Journal of Clinical Microbiology 2007; 45: 39964005.
23.R Development Core Team. R: A language and environment for statistical computing. Vienna: R Foundation for Statistical Computing, 2011 (http://www.R-project.org).
24.Kageyama T, et al. Broadly reactive and highly sensitive assay for Norwalk-like viruses based on real-time quantitative reverse transcription-PCR. Journal of Clinical Microbiology 2003; 41: 15481557.
25.Anderson AD, et al. A waterborne outbreak of Norwalk-like virus among snowmobilers – Wyoming, 2001. Journal of Infectious Diseases 2003; 187: 303306.
26.Kojima S, et al. Genogroup-specific PCR primers for detection of Norwalk-like viruses. Journal of Virological Methods 2002; 100: 107114.
27.Xerry J, et al. Transmission events within outbreaks of gastroenteritis determined through analysis of nucleotide sequences of the P2 domain of genogroup II noroviruses. Journal of Clinical Microbiology 2008; 46: 947953.
28.Kroneman A, et al. An automated genotyping tool for enteroviruses and noroviruses. Journal of Clinical Virology 2011; 51: 121125.
29.Tamura K, et al. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Molecular Biology and Evolution 2011; 28: 27312739.
30.New Zealand Food Safety Authority. Food control plan: food service and catering, 2011.
31.Verhoef L, et al. Selection of a phylogenetically informative region of the norovirus genome for outbreak linkage. Virus Genes 2012; 44: 818.
32.White KE, et al. A foodborne outbreak of Norwalk virus gastroenteritis. Evidence for post-recovery transmission. American Journal of Epidemiology 1986; 124: 120126.
33.Iversen AM, et al. Two outbreaks of foodborne gastroenteritis caused by a small round structured virus: evidence of prolonged infectivity in a food handler. Lancet 1987; 2: 556558.
34.Reid JA, et al. Role of infected food handler in hotel outbreak of Norwalk-like viral gastroenteritis: implications for control. Lancet 1988; 2: 321323.
35.Patterson T, Hutchings P, Palmer S. Outbreak of SRSV gastroenteritis at an international conference traced to food handled by a post-symptomatic caterer. Epidemiology and Infection 1993; 111: 157162.
36.Parashar UD, et al. An outbreak of viral gastroenteritis associated with consumption of sandwiches: implications for the control of transmission by food handlers. Epidemiology and Infection 1998; 121: 615621.
37.Telfer B, et al. A large outbreak of norovirus gastroenteritis linked to a catering company, New South Wales, October 2003. New South Wales Public Health Bulletin 2004; 15: 168171.
38.Malek M, et al. Outbreak of norovirus infection among river rafters associated with packaged delicatessen meat, Grand Canyon, 2005. Clinical Infectious Diseases 2009; 48: 3137.
39.Centers for Disease Control and Prevention. Multisite outbreak of norovirus associated with a franchise restaurant – Kent County, Michigan, May 2005. Morbidity and Mortality Weekly Report 2006; 55: 395397.
40.Curry A, et al. Small round structured viruses and persistence of infectivity in food handlers. Lancet 1987; 2: 864865.
41.Barrabeig I, et al. Foodborne norovirus outbreak: the role of an asymptomatic food handler. BMC Infectious Diseases 2010; 10: 269.
42.Daniels NA, et al. A foodborne outbreak of gastroenteritis associated with Norwalk-like viruses: first molecular traceback to deli sandwiches contaminated during preparation. Journal of Infectious Diseases 2000; 181: 14671470.
43.Bertrand I, et al. The impact of temperature on the inactivation of enteric viruses in food and water: a review. Journal of Applied Microbiology 2012; 112: 10591074.
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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
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