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    Sanstead, Erinn Kenyon, Cynthia Rowley, Seth Enns, Eva Miller, Claudia Ehresmann, Kristen and Kulasingam, Shalini 2015. Understanding Trends in Pertussis Incidence: An Agent-Based Model Approach. American Journal of Public Health, Vol. 105, Issue. 9, p. e42.


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Perplexities of pertussis: recent global epidemiological trends and their potential causes

  • D. W. JACKSON (a1) and PEJMAN ROHANI (a1) (a2) (a3)
  • DOI: http://dx.doi.org/10.1017/S0950268812003093
  • Published online: 16 January 2013
Abstract
SUMMARY

Recent much-publicized increases in pertussis case reports in some countries with high vaccine coverage have raised concerns about its current and future control. The ubiquity of this trend, however, remains unexamined. In an attempt to paint a global picture, we used case counts to determine which countries experienced statistically significant trends in incidence over the past two decades and to map changes in incidence during this period. These data reveal that pertussis resurgence is not a universal phenomenon. The heterogeneity in incidence trends, even in countries with superficially similar demography, socioeconomic conditions and vaccination programmes, is striking and requires explanation. In this opinion piece, we review and assess the multifaceted proposed explanations incorporating evolution, population dynamics, and the details of immunization programmes. While we do not solve the riddle that is pertussis epidemiology, we highlight critical aspects that are likely to hold the key to understanding its worldwide epidemiology.

Copyright
Corresponding author
*Author for correspondence: Dr D. W. Jackson, 323 West Hall, 1085 S. University, Ann Arbor, MI, USA. (Email: dougjack@dougjackson.net)
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This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

2. JDCherry . Pertussis in the preantibiotic and prevaccine era, with emphasis on adult pertussis. Clinical Infectious Diseases 1999; 28 (Suppl. 2): S107111.

3.S Mattoo , JD Cherry . Molecular pathogenesis, epidemiology, and clinical manifestations of respiratory infections due to Bordetella pertussis and other Bordetella subspecies. Clinical Microbiology Reviews 2005; 18: 326382.

4.NS Crowcroft , How best to estimate the global burden of pertussis? Lancet Infectious Diseases 2003; 3: 413418.

5. PRohani , JMDrake . The decline and resurgence of pertussis in the US. Epidemics 2011; 3: 183188.

8. HQuinn , PMcIntyre . The impact of adolescent pertussis immunization, 2004–2009: lessons from Australia. Bulletin of the World Health Organization 2011; 89: 666674.

9.A Gzyl , Pertussis in Poland. International Journal of Epidemiology 2004; 33: 358365.

10.ES Bamberger , I Srugo . What is new in pertussis? European Journal of Pediatrics 2008; 167: 133139.

11.EJ Gangarosa , Impact of anti-vaccine movements on pertussis control: the untold story. Lancet 1998; 351: 356361.

12.N Wood , P McIntyre . Pertussis: review of epidemiology, diagnosis, management and prevention. Paediatric Respiratory Reviews 2008; 9: 201211.

16.P Rohani , DJD Earn , BT Grenfell . Opposite patterns of synchrony in sympatric disease metapopulations. Science 1999; 286: 968971.

17.H Broutin , Impact of vaccination and birth rate on the epidemiology of pertussis: a comparative study in 64 countries. Proceedings of the Royal Society of London, Series B: Biological Sciences 2010; 277: 32393245.

18. HJWearing , PRohani . Estimating the duration of pertussis immunity using epidemiological signatures. PLoS Pathogens 2009; 5: e1000647.

19. BNtezayabo , GDe Serres , BDuval . Pertussis resurgence in Canada largely caused by a cohort effect. Pediatric Infectious Disease Journal 2003; 22: 2227.

20.JA Clarkson , PE Fine . The efficiency of measles and pertussis notification in England and Wales. International Journal of Epidemiology 1985; 14: 153168.

21.TJ Doyle , MK Glynn , SL Groseclose . Completeness of notifiable infectious disease reporting in the United States: an analytical literature review. American Journal of Epidemiology 2002; 155: 866874.

22.PJ Spokes , HE Quinn , JM McAnulty . Review of the 2008–2009 pertussis epidemic in NSW: notifications and hospitalisations. New South Wales Public Health Bulletin 2010; 21: 167173.

23. NSCrowcroft . Whooping cough – a continuing problem. British Medical Journal 2002; 324: 15371538.

24. QHe , JMertsola . Factors contributing to pertussis resurgence. Future Microbiology 2008; 3: 329339.

26.NJ Gay , E Miller . Pertussis transmission in England and Wales. Lancet 2000; 355: 15531554.

27. MTanaka , Trends in pertussis among infants in the United States, 1980–1999. Journal of the American Medical Association 2003; 290: 29682975.

28.H Campbell , Accelerating control of pertussis in England and Wales. Emerging Infectious Diseases 2012; 18: 3847.

29.JD Cherry . Pertussis in adults. Annals of Internal Medicine 1998; 128: 6466.

30. PRohani , DJDEarn , BTGrenfell . Pertussis transmission in England and Wales – reply. Lancet 2000; 355: 15531554.

31. HTHNguyen , PRohani . Noise, nonlinearity and seasonality: the epidemics of whooping cough revisited. Journal of the Royal Society Interface 2008; 5: 403413.

34.NS Crowcroft , RG Pebody . Recent developments in pertussis. Lancet 2006; 367: 19261936.

35.FR Mooi . Bordetella pertussis strains with increased toxin production associated with pertussis resurgence. Emerging Infectious Diseases 2009; 15: 12061213.

36.TA Clark , NE Messonnier , SC Hadler . Pertussis control: time for something new? Trends in Microbiology 2012; 20: 211213.

37.JD Cherry . The present and future control of pertussis. Clinical Infectious Diseases 2010; 51: 663667.

38.SL Sheridan , Number and order of whole cell pertussis vaccines in infancy and disease protection. Journal of the American Medical Association 2012; 308: 454456.

40.T Tan , E Trindade , D Skowronski . Epidemiology of pertussis. Pediatric Infectious Disease Journal 2005; 24: S10S18.

41.MC Shinall , Potential impact of acceleration of the pertussis vaccine primary series for infants. Pediatrics 2008; 122: 10211026.

42. AIFecsik . Studies on antibody production: XI. Variation in the secondary response as a function of the interval between two antigenic stimuli. Journal of Experimental Medicine 1964; 120: 10411049.

44.J Taranger , Vaccination of infants with a four-dose and a three-dose vaccination schedule. Vaccine 1999; 18: 884891.

45.R Booy , Immunogenicity of combined diphtheria, tetanus, and pertussis vaccine given at 2, 3, and 4 months versus 3, 5, and 9 months of age. Lancet 1992; 339: 507510.

47.T Jefferson , M Rudin , C DiPietrantonj . Systematic review of the effects of pertussis vaccines in children. Vaccine 2003; 21: 20032014.

48. SBOmer , Nonmedical exemptions to school immunization requirements: Secular trends and association of state policies with pertussis incidence. Journal of the American Medical Association 2006; 296: 17571763.

49. SBOmer , Geographic clustering of nonmedical exemptions to school immunization requirements and associations with geographic clustering of pertussis. American Journal of Epidemiology 2008; 168: 13891396.

50. RMAnderson , RMMay , AMcLean . Possible demographic consequences of AIDS in developing countries. Nature 1988; 332: 228234.

51. RMAnderson , RMMay . Infectious Diseases of Humans: Dynamics and Control. Oxford, New York: Oxford University Press, 1991.

52.AM Wendelboe , Duration of immunity against pertussis after natural infection or vaccination. Pediatric Infectious Disease Journal 2005; 24: S58.

54.P Rohani , X Zhong , AA King . Contact network structure explains the changing epidemiology of pertussis. Science 2010; 330: 982985.

56. JDCherry . Epidemiological, clinical, and laboratory aspects of pertussis in adults. Clinical Infectious Diseases 1999; 28 (Suppl 2): S112117.

58. Mvan Boven , Pathogen adaptation under imperfect vaccination: implications for pertussis. Proceedings of the Royal Society of London, Series B: Biological Sciences 2005; 272: 16171624.

59.J Schellekens , C-HW von Konig , P Gardner . Pertussis sources of infection and routes of transmission in the vaccination era. Pediatric Infectious Disease Journal 2005; 24: S19S24.

60.JS Lavine , AA King , ON Bjørnstad . Natural immune boosting in pertussis dynamics and the potential for long-term vaccine failure. Proceedings of the National Academy of Sciences USA 2011; 108: 72597264.

61.R Aguas , G Gonçalves , MGM Gomes . Pertussis: increasing disease as a consequence of reducing transmission. Lancet Infectious Diseases 2006; 6: 112117.

62.LA Cattaneo , The seroepidemiology of Bordetella pertussis infections: a study of persons ages 1–65 years. Journal of Infectious Diseases 1996; 173: 12561259.

63.FR Mooi , IHM van Loo , AJ King . Adaptation of Bordetella pertussis to vaccination: a cause for its reemergence? Emerging Infectious Diseases 2001; 7: 526528.

64.NK Fry , Genotypic variation in the Bordetella pertussis virulence factors pertactin and pertussis toxin in historical and recent clinical isolates in the United Kingdom. Infection and Immunity 2001; 69: 55205528.

66. OBorisova , Antigenic divergence between Bordetella pertussis clinical isolates from Moscow, Russia, and vaccine strains. Clinical and Vaccine Immunology 2007; 14: 234238.

67. AAdvani , Appearance of Fim3 and ptxP3-Bordetella pertussis strains, in two regions of Sweden with different vaccination programs. Vaccine 2011; 29: 34383442.

68. AKodama , Antigenic divergence suggested by correlation between antigenic variation and pulsed-field gel electrophoresis profiles of Bordetella pertussis isolates in Japan. Journal of Clinical Microbiology 2004; 42: 54535457.

69.FR Mooi . Bordetella pertussis and vaccination: the persistence of a genetically monomorphic pathogen. Infection, Genetics and Evolution 2010; 10: 3649.

70.A Elomaa , Population dynamics of Bordetella pertussis in Finland and Sweden, neighbouring countries with different vaccination histories. Vaccine 2007; 25: 918926.

71.S Octavia , Newly emerging clones of Bordetella pertussis carrying prn2 and ptxP3 alleles implicated in Australian pertussis epidemic in 2008–2010. Journal of Infectious Diseases 2012; 205: 12201224.

72.M van Gent , Small mutations in Bordetella pertussis are associated with selective sweeps. PLoS ONE 2012; 7: e46407.

73.AJ Schmidtke , Population diversity among Bordetella pertussis isolates, United States, 1935–2009. Emerging Infectious Diseases 2012; 18: 12481255.

74.P Bajardi , Human mobility networks, travel restrictions, and the global spread of 2009 H1N1 pandemic. PLoS ONE 2011; 6: e16591.

75. CARussell , The global circulation of seasonal influenza A (H3N2) viruses. Science 2008; 320: 340346.

76.SY Shin , Drug-resistant pandemic (H1N1) 2009, South Korea. Emerging Infectious Diseases 2011; 17: 702704.

77.AM Wensing , Prevalence of drug-resistant HIV-1 variants in untreated individuals in Europe: implications for clinical management. Journal of Infectious Diseases 2005; 192: 958966.

78. CWongsrichanalai , ALPickard . Epidemiology of drug-resistant malaria. Lancet Infectious Diseases 2002; 2: 209218.

80.D Blumenthal , Data withholding in genetics and the other life sciences: prevalences and predictors. Academic Medicine 2006; 81: 137145.

81.E Pisani , Time for fair trade in research data. Lancet 2010; 375: 703705.

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