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    Janda, J. Michael Newton, Anna E. and Bopp, Cheryl A. 2015. Vibriosis. Clinics in Laboratory Medicine, Vol. 35, Issue. 2, p. 273.

    Jones, Benjamin Burkhart, Joshua and Sonpavde, Guru 2015. Danger on a Half Shell: Vibrio vulnificus Septicemia. The American Journal of Medicine, Vol. 128, Issue. 5, p. 475.

    Kim, Chang Seong Bae, Eun Hui Ma, Seong Kwon and Kim, Soo Wan 2015. Severe septicemia, necrotizing fasciitis, and peritonitis due to Vibrio vulnificus in a patient undergoing continuous ambulatory peritoneal dialysis: a case report. BMC Infectious Diseases, Vol. 15, Issue. 1,

    Kuo, Soong-Yu Chou, Miao-Chen Lee, Shin-Luen Wang, Yu Chen, Chun-Liang Lin, Pei-Ting and Lo, Horng-Ren 2015. Vibrio vulnificus RtxA1 modulated calcium flux contributes reduced internalization in phagocytes. Life Sciences, Vol. 132, p. 55.


Pre-existing medical conditions associated with Vibrio vulnificus septicaemia

  • M. P. MENON (a1), P. A. YU (a1), M. IWAMOTO (a1) and J. PAINTER (a1)
  • DOI:
  • Published online: 10 July 2013

Vibrio vulnificus (Vv) can result in severe disease. Although pre-existing liver disease is a recognized risk factor for serious infection, the relative importance of other comorbidities has not been fully assessed. We analysed reports of Vv infections submitted to CDC from January 1988 to September 2006 in order to assess the role of pre-existing conditions contributing to severe outcomes. A total of 1212 patients with Vv infection were reported. Only patients with liver disease [adjusted odds ratio (aOR) 5·1)] were more likely to become septic when exposure was due to contaminated food. Patients with liver disease (aOR 4·1), a haematological disease (aOR 3·2), or malignancy (aOR 3·2) were more likely to become septic when infection was acquired via a non-foodborne exposure. As such, patients with these pre-existing medical conditions should be advised of the risk of life-threatening illness after eating undercooked contaminated seafood or exposing broken skin to warm seawater.

Corresponding author
*Author for correspondence: Dr M. P. Menon, 1600 Clifton Road, MS A06, Atlanta, GA 30329, USA. (Email:
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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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