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Prevalence of hepatitis C virus and hepatitis B virus infections in HIV-positive Chinese patients

  • Y. X. YAN (a1), Y. Q. GAO (a2), X. SUN (a2), W. WANG (a1), X. J. HUANG (a2), T. ZHANG (a2), M. LI (a1), C. P. ZANG (a3), Z. C. LI (a2) and H. WU (a2)
  • DOI:
  • Published online: 02 July 2010

To evaluate the prevalence of hepatitis C virus (HCV) and/or hepatitis B virus (HBV) infections in HIV-infected patients in China, an epidemiological serosurvey was conducted from May 2007 to September 2008 using a random cluster sampling design of infectious disease hospitals in seven high HIV-prevalent provinces (municipalities). Univariate analysis and logistic regression were used to study the determinants of HIV and HBV and/or HCV co-infection. The overall prevalence was 41·83% (95% CI 40·36–43·30) for anti-HCV and 12·49% (95% CI 11·50–13·48) for HBsAg, respectively. The prevalence of anti-HCV and HBsAg varied according to the route of HIV transmission. Compared to those with sexually acquired HIV infection, intravenous drug users and blood donors/recipients had the greatest risk of carrying anti-HCV. Needle sharing and unprotected sexual exposures are important modes of transmission for HBV. Further interventions including health education and harm reduction strategies should be implemented in high-risk populations.

Corresponding author
*Author for correspondence: Dr Hao Wu, STD and AIDS Clinical Center, Beijing Youan Hospital, Capital Medical University, No. 8 Xitoutiao, You An Men, Beijing100069, P.R. China. (Email:
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