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Report of a hospital neonatal unit outbreak of community-associated methicillin-resistant Staphylococcus aureus

  • I. M. GOULD (a1), E. K. GIRVAN (a2), R. A. BROWNING (a3), F. M. MACKENZIE (a1) and G. F. S. EDWARDS (a2)
  • DOI:
  • Published online: 10 March 2009

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) with the type IV staphylococcal chromosomal cassette mec (SCCmec) is rarely reported as being acquired in hospital. We report a hospital outbreak, in Grampian, Scotland, of eight cases of skin and soft-tissue infections due to such a strain. All patients had been in the labour, delivery and maternity units of a small community hospital during a 7-month period. Typing by pulsed-field gel electrophoresis showed the isolates to be a single strain closely related to the USA800 lineage (paediatric clone) and additional typing confirmed it as ST5-MRSA-IV. Genes for exfoliative toxin A (ETA) and enterotoxin D were detected by PCR in all the isolates although none carried the Panton–Valentine leukocidin gene. Region-wide surveillance of over 6000 MRSA isolates collected from 1998 to 2004 showed that 95 (1·6%) were closely related to the outbreak strain although only 60 carried the ETA gene. The strain has not been seen elsewhere in Scotland.

Corresponding author
*Author for correspondence: Dr I. M. Gould, Department of Microbiology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, AB25 2ZN, UK. (Email:
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Epidemiology & Infection
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