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Psychiatrists’ attitude to antipsychotic depot treatment in patients with first-episode schizophrenia

Published online by Cambridge University Press:  16 April 2020

S. Heres ,
T. Reichhart ,
J. Hamann ,
R. Mendel ,
S. Leucht  and
W. Kissling
S. Heres*
Affiliation:
Klinik und Poliklinik fuer Psychiatrie und Psychotherapie, der Technischen Universitaet Muenchen, am Klinikum rechts der Isar, Moehlstrasse 26, 81675Muenchen, Germany
T. Reichhart
Affiliation:
Klinik und Poliklinik fuer Psychiatrie und Psychotherapie, der Technischen Universitaet Muenchen, am Klinikum rechts der Isar, Moehlstrasse 26, 81675Muenchen, Germany
J. Hamann
Affiliation:
Klinik und Poliklinik fuer Psychiatrie und Psychotherapie, der Technischen Universitaet Muenchen, am Klinikum rechts der Isar, Moehlstrasse 26, 81675Muenchen, Germany
R. Mendel
Affiliation:
Klinik und Poliklinik fuer Psychiatrie und Psychotherapie, der Technischen Universitaet Muenchen, am Klinikum rechts der Isar, Moehlstrasse 26, 81675Muenchen, Germany
S. Leucht
Affiliation:
Klinik und Poliklinik fuer Psychiatrie und Psychotherapie, der Technischen Universitaet Muenchen, am Klinikum rechts der Isar, Moehlstrasse 26, 81675Muenchen, Germany
W. Kissling
Affiliation:
Klinik und Poliklinik fuer Psychiatrie und Psychotherapie, der Technischen Universitaet Muenchen, am Klinikum rechts der Isar, Moehlstrasse 26, 81675Muenchen, Germany
*
*Corresponding author. Tel.: +49 89 4140-4227; fax: +49 89 4140 4898. E-mail address: s.heres@lrz.tum.de (S. Heres).
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Abstract

Objective

Despite good clinical evidence, depot antipsychotics are only seldom prescribed to patients with first episode schizophrenia. The present study aims at investigating psychiatrists’ reasons for this reservation.

Method

We surveyed 198 psychiatrists on their attitude toward offering depot treatment to first episode patients (FEP). Participants scored the extent of influence of individual factors on their decision on a seven-point-scale, additional data on their prescription practice and estimation of the relapse risk of FEP were collected.

Results

Psychiatrists reported that only three out of 12 factors were of influence. These were the limited availability of different second generation antipsychotic depot drugs, the frequent rejection of the depot offer by the patients and the patients’ skepticism based on the lack in experience of a relapse.

Conclusions

There is actually little specific reason for not prescribing depot to FEP according to the current survey. For those factors being reported to be of influence, psychoeducation, including profound information on depot treatment, the development of additional SGA depot drugs and the standard offer of depot treatment to all FEP in a shared-decision-making may be considered.

Type
Original article
Information
European Psychiatry , Volume 26 , Issue 5 , August 2011 , pp. 297 - 301
Copyright
Copyright © Elsevier Masson SAS 2011

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Footnotes

Abbreviations, FEP first episode patients, FGA first generation antipsychotics, SD standard deviation , SGA second generation antipsychotics

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