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Nosological validity of dysthymia. Part II: familial, comorbidity, biological and psychological data

Published online by Cambridge University Press:  16 April 2020

L Waintraub  and
JD Guelfi
L Waintraub
Affiliation:
Paris V, Cochin-Port-Royal University, CHS Paul Guiraud, 54 Avenue de la République, 94806 Villejuif cedex, France
JD Guelfi
Affiliation:
Paris XI University, Hôpital Paul Brousse, 94804 Villejuif cedex, France
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Summary

If some recent studies seem to reveal a more specific familial relationship for dysthymia in addition to a previously known familial relationship to mood disorders, and if results concerning the relationship between dysthymia and depressive personality as well as the search for possible biological and psychological correlates support the nosological validity of dysthymia, comorbidity studies raise difficult questions. Both comorbidity studies with Axis I and Axis II disorders challenge the validity of dysthymia, but as well they question the categorical model presently in use more than the validity of a definite category.

However, there are now enough data confirming some of the hypotheses implied by the nosological construct of dysthymia inside this model for this category not to be discarded. For instance, dysthymia is definitely not a personality disorder, and appears also distinct from major depression. The problem of the complex nature of the relationship between dysthymia and major depression still remains unsolved.

Keywords

dysthymiamajor depressionpersonality disordersvalidityfamily studiescomorbiditybiological studiespsychological studies
Type
Research Article
Information
European Psychiatry , Volume 13 , Issue 4 , July 1998 , pp. 181 - 187
Copyright
Copyright © Elsevier, Paris 1998

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