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P0324 - Differences in brain electrical activity after the cerebellar hemisphere and the vermis rTMS

Published online by Cambridge University Press:  16 April 2020

B. Tislerova ,
M. Kopecek ,
P. Sos ,
J. Audrlicky ,
M. Brunovsky  and
J. Horacek
B. Tislerova
Affiliation:
Prague Psychiatric Center, Prague, Czech Republic Charles University 3rd Faculty of Medicine, Prague, Czech Republic Center of Neuropsychiatric Studies in Prague, Prague, Czech Republic
M. Kopecek
Affiliation:
Prague Psychiatric Center, Prague, Czech Republic Charles University 3rd Faculty of Medicine, Prague, Czech Republic Center of Neuropsychiatric Studies in Prague, Prague, Czech Republic
P. Sos
Affiliation:
Prague Psychiatric Center, Prague, Czech Republic Charles University 3rd Faculty of Medicine, Prague, Czech Republic Center of Neuropsychiatric Studies in Prague, Prague, Czech Republic
J. Audrlicky
Affiliation:
Charles University 3rd Faculty of Medicine, Prague, Czech Republic
M. Brunovsky
Affiliation:
Prague Psychiatric Center, Prague, Czech Republic Charles University 3rd Faculty of Medicine, Prague, Czech Republic Center of Neuropsychiatric Studies in Prague, Prague, Czech Republic
J. Horacek
Affiliation:
Prague Psychiatric Center, Prague, Czech Republic Charles University 3rd Faculty of Medicine, Prague, Czech Republic Center of Neuropsychiatric Studies in Prague, Prague, Czech Republic

Abstract

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Background:

The previous studies have detected changes of brain electrical activity after the cerebellar hemisphere rTMS and the vermis rTMS. We supposed that right cerebellar 1Hz rTMS evokes changes in the left frontal cortex. The aim of our study was to determine if 1Hz cerebellar hemisphere and 1 Hz vermis rTMS induces different effect in frontal electrical activity.

Methods:

We used 10 minutes of 1 Hz rTMS (with 600 impulses) in two sessions (first session- application over the right cerebellar hemisphere, second over the vermis). 31-channel EEG was recorded in 5 right-handed healthy volunteers before and after rTMS. The 3D distribution of the current density was revealed by a method of qEEG- Low Resolution Brain Electromagentic Tomography (LORETA, Pascual-Marqui et al. 1994; 1999).

Results:

After 1 Hz right cerebellar hemisphere rTMS the current density decreased in the alfa2, beta1, beta2 and beta3 band over the frontal cortex including medial frontal cortex and the anterior cingulate (p<0.01). After 1 Hz vermis rTMS we found no significant changes.

Conclusions:

Our results suggest the possibility to influence the frontal cortical activity by means of the cerebellar hemisphere rTMS. No significant changes after 1Hz vermis rTMS may suggest either large distance between the rTMS coil and the vermis or our sample is too small to make definitive conclusions.

Supported by MZ0PCP2005 and 1M0517

Type
Poster Session II: ECT/ TMS
Information
European Psychiatry , Volume 23 , Issue S2: 16th AEP Congress - Abstract book - 16th AEP Congress , April 2008 , pp. S287 - S288
Copyright
Copyright © European Psychiatric Association 2008
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