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P0342 - Neuropsychological changes in patients after normothermic versus hypothermic CABG - randomized trial

Published online by Cambridge University Press:  16 April 2020

R. Wojtynska
Affiliation:
Department of Psychiatry, Wroclaw Medical University, Wroclaw, Poland
J. Rymaszewska
Affiliation:
Department of Psychiatry, Wroclaw Medical University, Wroclaw, Poland

Abstract

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Aim:

to assess changes in cognitive functioning of Coronary Artery Bypass Grafting patients including effect of hypothermia and normothermia.

Methods:

Randomly selected normothermic (N, n=30) and hypothermic (H, n=21) patients were assessed 3-10 days before and 7-10 days after CABG using Bourdon Test, RAVLT, Tower of Hanoi Test, TMT: A&B, Benton Visual Retention Test, Digit Span, Digit Symbol, Verbal Fluency Test: Supermarket, Raven and Vocabulary Scales. Cognitive impairment rating (CIR) was defined as at least 1 SD scores deterioration, or change into worse category in at least 20% of tests.

Results:

Cognitive impairment was observed in 10 out of 12 tests. Changes were significantly greater in H-group in immediate recall visual memory, visual-motor coordination and working memory and in N-group in immediate verbal recall. Regarding mean changes impairment of immediate visual memory were observed in 60% of patients, whereas impairment of delayed recall auditory-verbal memory, immediate verbal memory, psychomotor speed, visual perception, language, attention -in 20-30%. The changes were similar for both methods (p=0.465). In N-group deterioration was observed in 26.7%, improvement in 5% of measures; in H-group deterioration– 28.6%, improvement- 7%. On average deterioration of at least 1 category was observed in 3 of 11 tests. CIR was met in 64.7% of the whole sample. There was no significant differences between the methods according to this criterion (N- 60%; H- 71.4%).

Conclusions:

CABG with extracorporeal circulation influences on cognitive functioning. Results suggest impairment in the field of coordinating complex cognitive processes rather than executive functions regardless of method used during CABG.

Type
Poster Session II: Memory And Cognitive Disorders
Copyright
Copyright © European Psychiatric Association 2008
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