Hostname: page-component-76fb5796d-25wd4 Total loading time: 0 Render date: 2024-04-27T21:09:28.165Z Has data issue: false hasContentIssue false
  • English
  • Français

Patient satisfaction with psychotropic drugs: Validation of the PAtient SAtisfaction with Psychotropic (PASAP) scale in patients with bipolar disorder

Published online by Cambridge University Press:  15 April 2020

C. Nordon ,
B. Falissard ,
S. Gerard ,
J. Angst ,
J.M. Azorin ,
A. Luquiens ,
C. Reed ,
M. Lukasiewicz  and
I. Gasquet
C. Nordon*
Affiliation:
INSERM 669, Paris-Sud University and Paris-Descartes University, Maison des Adolescents, 97, boulevard de Port-Royal, 75014Paris, France
B. Falissard
Affiliation:
INSERM 669, Paris-Sud University and Paris-Descartes University, Maison des Adolescents, 97, boulevard de Port-Royal, 75014Paris, France
S. Gerard
Affiliation:
PRA Structure - Économie de la Santé, Lilly France 17, rue Pagès, 92150Suresnes, France
J. Angst
Affiliation:
Zurich University Psychiatric Hospital, Lenggstr. 31, Mail Box 68, CH-8029Zurich, Switzerland
J.M. Azorin
Affiliation:
Service de psychiatrie adulte, Sainte-Marguerite University Hospital Centre, 270, boulevard de Sainte-Marguerite, 13009Marseille, France
A. Luquiens
Affiliation:
INSERM 669, Paris-Sud University and Paris-Descartes University, Maison des Adolescents, 97, boulevard de Port-Royal, 75014Paris, France Département de Psychiatrie et d’Addictologie, Paul Brousse Hospital, 12, avenue Paul-Vaillant-Couturier, 94804Villejuif cedex, France
C. Reed
Affiliation:
Lilly Research Centre, Eli Lilly and Company Limited, Erl Wood Manor, Sunninghill road, Windlesham, Surrey, GU20 6PH, United Kingdom
M. Lukasiewicz
Affiliation:
INSERM 669, Paris-Sud University and Paris-Descartes University, Maison des Adolescents, 97, boulevard de Port-Royal, 75014Paris, France
I. Gasquet
Affiliation:
INSERM 669, Paris-Sud University and Paris-Descartes University, Maison des Adolescents, 97, boulevard de Port-Royal, 75014Paris, France Direction de la Politique Médicale, Assistance Publique–Hôpitaux de Paris, 3, avenue Victoria, 75004Paris, France
*
* Corresponding author. Tel.: +33 6 15 40 33 86. E-mail address: nordon.clementine@gmail.com (C. Nordon).
Get access

Abstract

Purpose:

The PAtient SAtisfaction with Psychotropic (PASAP) scale is a self-completed questionnaire measuring satisfaction with psychotropic medication. The aim of the study was to describe its development in French and its psychometric properties.

Materials and methods:

Scale construction was based on an extensive search of the literature. The item reduction process required semi-structured interviews of psychiatric outpatients (n = 30). The final version of the PASAP is a 9-item, 5-point Likert-type scale, covering the scope of effectiveness and adherence. To assess the psychometric properties of the scale, French patients with an acute manic episode (n = 314) from a large European observational cohort completed the PASAP scale 3 months after psychotropic treatment initiation/change. Internal validity and reliability were assessed using principal component analysis (PCA). Concurrent validity was assessed using comparisons to physician-rated satisfaction with life, illness severity, mood relapse, compliance and side effects.

Results:

Participation rate was 68.4%. PCA was in favour of uni-dimensionality. Cronbach's α coefficient was 0.85 (95%CI 0.83–0.88). All five concurrent measures were significantly associated with the PASAP score.

Conclusion:

The PASAP scale showed good psychometric properties in a large bipolar population and thus seems adequate for evaluating treatment satisfaction. Its short length and good acceptability makes it suitable for clinical research.

Keywords

Psychometry and assessments in psychiatryPatient-reported outcomesPatient satisfactionPsychotropic drugsValidation study
Type
Original article
Information
European Psychiatry , Volume 29 , Issue 3 , March 2014 , pp. 183 - 190
Copyright
Copyright © European Psychiatric Association 2014

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

American Psychiatric Association. Diagnostic and statistical manual of mental disorders. Fourth ed.Washington DC: American Psychiatric Association; 1994.Google Scholar
Asadi-Lari, M, Packham, C, Gray, DPatients’ satisfaction and quality of life in coronary artery disease. Health Qual Life Outcomes 2003;1:57–63.CrossRefGoogle ScholarPubMed
Atkinson, MJ, Sinha, A, Hass, SL, Colman, SS, Kumar, RN, Brod, Met al.Validation of a general measure of treatment satisfaction, the Treatment Satisfaction Questionnaire for Medication (TSQM), using a national panel study of chronic disease. Health Qual Life Outcomes 2004;2:12–24.CrossRefGoogle Scholar
Awad, AG, Voruganti, LNNew antipsychotics, compliance, quality of life, and subjective tolerability--are patients better off?. Can J Psychiatry 2004;49:297–302.CrossRefGoogle ScholarPubMed
Awad, AG, Voruganti, LN, Heslegrave, RJ, Hogan, TPAssessment of the patient's subjective experience in acute neuroleptic treatment: implications for compliance and outcome. Int Clin Psychopharmacol 1996;11(Suppl. 2):55–59.CrossRefGoogle ScholarPubMed
Azorin, JM, Luquiens, A, Aubrun, E, Reed, C, Gasquet, I, Lukasiewicz, MManagement of patients with acute manic or mixed episodes and outcome at three months. Encephale 2010;36:226–235.CrossRefGoogle ScholarPubMed
Ben-Sira, ZAffective and instrumental components in the physician-patient relationship: an additional dimension of interaction theory. J Health Soc Behav 1980;21:170–180.CrossRefGoogle ScholarPubMed
Bos, A, Vosselman, N, Hoogstraten, J, Prahl-Andersen, BPatient compliance: a determinant of patient satisfaction?. Angle Orthod 2005;75:526–531.Google ScholarPubMed
Bradley, CDiabetes treatment satisfaction questionnaire. Change version for use alongside status version provides appropriate solution where ceiling effects occur. Diabetes Care 1999;22:530–532.CrossRefGoogle ScholarPubMed
Cappelleri, JC, Cefalu, WT, Rosenstock, J, Kourides, IA, Gerber, RATreatment satisfaction in type 2 diabetes: a comparison between an inhaled insulin regimen and a subcutaneous insulin regimen. Clin Ther 2002;24:552–564.CrossRefGoogle Scholar
Cattell, RBThe scree test for the number of factors. Multivariate Behav Res 1966;1:245–276.CrossRefGoogle ScholarPubMed
Cherkin, D, Deyo, RA, Berg, AOEvaluation of a physician education intervention to improve primary care for low-back pain. II. Impact on patients. Spine (Phila Pa 1976) 1991;16:1173–1178.CrossRefGoogle ScholarPubMed
Clotet, B, Carmena, J, Pulido, F, Luque, I, Rodriguez-Alcantara, FAdherence, quality of life, and general satisfaction with co-formulated zidovudine, lamivudine, and abacavir on antiretroviral-experienced patients. HIV Clin Trials 2004;5:33–39.Google ScholarPubMed
Cronbach, LJCoefficient alpha and the internal structure of tests. Psychometrika 1951;16:297–334.CrossRefGoogle Scholar
Day, JC, Bentall, RP, Roberts, C, Randall, F, Rogers, A, Cattell, Det al.Attitudes toward antipsychotic medication: the impact of clinical variables and relationships with health professionals. Arch Gen Psychiatry 2005;62:717–724.CrossRefGoogle ScholarPubMed
Day, JC, Bentall, RP, Warner, SSchizophrenic patients’ experiences of neuroleptic medication: a Q-methodological investigation. Acta Psychiatr Scand 1996;93:397–402.CrossRefGoogle ScholarPubMed
de Haan, L, Weisfelt, M, Dingemans, PM, Linszen, DH, Wouters, LPsychometric properties of the Subjective Well-Being Under Neuroleptics Scale and the Subjective Deficit Syndrome Scale. Psychopharmacology (Berl) 2002;162:24–28.CrossRefGoogle ScholarPubMed
Falissard, BMesurer la subjectivité en santé : perspective méthodologique et statistique. Paris: Masson; 2001.Google Scholar
Fitzpatrick, RSurveys of patients satisfaction: I--Important general considerations. BMJ 1991;302:887–889.CrossRefGoogle ScholarPubMed
Gasquet, I, Tcherny-Lessenot, S, Lepine, JP, Falissard, BPatient satisfaction with psychotropic drugs: sensitivity to change and relationship to clinical status, quality-of-life, compliance and effectiveness of treatment. Results from a nation-wide 6-month prospective study. Eur Psychiatry 2006;21:531–538.CrossRefGoogle ScholarPubMed
Gasquet, I, Villeminot, S, Dos Santos, C, Vallet, O, Verdier, A, Kovess, Vet al.Cultural adaptation and validation of questionnaires measuring satisfaction with the French health system. Sante Publique 2003;15:383–402.CrossRefGoogle ScholarPubMed
Gasquet, I, Villeminot, S, Estaquio, C, Durieux, P, Ravaud, P, Falissard, BConstruction of a questionnaire measuring outpatients’ opinion of quality of hospital consultation departments. Health Qual Life Outcomes 2004;2:43.CrossRefGoogle ScholarPubMed
Gharabawi, GM, Greenspan, A, Rupnow, MF, Kosik-Gonzalez, C, Bossie, CA, Zhu, Yet al.Reduction in psychotic symptoms as a predictor of patient satisfaction with antipsychotic medication in schizophrenia: data from a randomized double-blind trial. BMC Psychiatry 2006;6:45.CrossRefGoogle ScholarPubMed
Gigantesco, A, Morosini, R, Bazzoni, AQuality of psychiatric care: validation of an instrument for measuring inpatient opinion. Int J Qual Health Care 2003;15:73–78.CrossRefGoogle ScholarPubMed
Goetz, I, Tohen, M, Reed, C, Lorenzo, M, Vieta, EFunctional impairment in patients with mania: baseline results of the EMBLEM study. Bipolar Disord 2007;9:45–52.CrossRefGoogle ScholarPubMed
Hogan, TP, Awad, AG, Eastwood, RA self-report scale predictive of drug compliance in schizophrenics: reliability and discriminative validity. Psychol Med 1983;13:177–183.CrossRefGoogle ScholarPubMed
Kalda, R, Polluste, K, Lember, MPatient satisfaction with care is associated with personal choice of physician. Health Policy 2003;64:55–62.CrossRefGoogle ScholarPubMed
Kampman, O, Lehtinen, K, Lassila, V, Leinonen, E, Poutanen, O, Koivisto, AAttitudes towards neuroleptic treatment: reliability and validity of the attitudes towards neuroleptic treatment (ANT) questionnaire. Schizophr Res 2000;45:223–234.CrossRefGoogle ScholarPubMed
Keller, MB, Lavori, PW, Friedman, B, Nielsen, E, Endicott, J, McDonald-Scott, Pet al.The longitudinal interval follow-up evaluation. A comprehensive method for assessing outcome in prospective longitudinal studies. Arch Gen Psychiatry 1987;44:540–548.CrossRefGoogle ScholarPubMed
Kerse, N, Buetow, S, Mainous, AG, Young, G, Coster, G, Arroll, BPhysician-patient relationship and medication compliance: a primary care investigation. 3rd. Ann Fam Med 2004;2:455–461.CrossRefGoogle ScholarPubMed
Koivumaa-Honkanen, HT, Honkanen, R, Antikainen, R, Hintikka, J, Viinamaki, HSelf-reported life satisfaction and treatment factors in patients with schizophrenia, major depression and anxiety disorder. Acta Psychiatr Scand 1999;99:377–384.CrossRefGoogle ScholarPubMed
Lebow, JPragmatic decisions in the evaluation of consumer satisfaction with mental health treatment. Eval Program Plann 1982;5:349–356.CrossRefGoogle ScholarPubMed
Liang, MH, Fossel, AH, Larson, MGComparisons of five health status instruments for orthopedic evaluation. Med Care 1990;28:632–642.CrossRefGoogle ScholarPubMed
Macfarlane, J, Holmes, W, Macfarlane, R, Britten, NInfluence of patients’ expectations on antibiotic management of acute lower respiratory tract illness in general practice: questionnaire study. BMJ 1997;315:1211–1214.CrossRefGoogle ScholarPubMed
McCabe, R, Saidi, M, Priebe, SPatient-reported outcomes in schizophrenia. Br J Psychiatry Suppl 2007;50:s21–s28.CrossRefGoogle Scholar
Moret, L, Nguyen, JM, Pillet, N, Falissard, B, Lombrail, P, Gasquet, IImprovement of psychometric properties of a scale measuring inpatient satisfaction with care: a better response rate and a reduction of the ceiling effect. BMC Health Serv Res 2007;7:197.CrossRefGoogle Scholar
Naber, DA self-rating to measure subjective effects of neuroleptic drugs, relationships to objective psychopathology, quality of life, compliance and other clinical variables. Int Clin Psychopharmacol 1995;10(Suppl. 3):133–138.Google ScholarPubMed
Naber, D, Karow, AGood tolerability equals good results: the patient's perspective. Eur Neuropsychopharmacol 2001;11(Suppl. 4):S391–S396.CrossRefGoogle ScholarPubMed
Naber, D, Moritz, S, Lambert, M, Pajonk, FG, Holzbach, R, Mass, Ret al.Improvement of schizophrenic patients’ subjective well-being under atypical antipsychotic drugs. Schizophr Res 2001;50:79–88.CrossRefGoogle ScholarPubMed
Perreault, M, Rogers, WL, Leichner, P, Sabourin, SPatients’ requests and satisfaction with services in an outpatient psychiatric setting. Psychiatr Serv 1996;47:287–292.Google Scholar
Redekop, WK, Koopmanschap, MA, Stolk, RP, Rutten, GE, Wolffenbuttel, BH, Niessen, LWHealth-related quality of life and treatment satisfaction in Dutch patients with type 2 diabetes. Diabetes Care 2002;25:458–463.CrossRefGoogle ScholarPubMed
Rouquette, A, Falissard, BSample size requirements for the internal validation of psychiatric scales. Int J Methods Psychiatr Res 2011;20:235–249.CrossRefGoogle ScholarPubMed
Ruggeri, M, Dall’Agnola, R, Bisoffi, GFactor analysis of the Verona service satisfaction scale-82 and development of reduced versions. Intern J Meth Psychiatr Res 1996;6:23–38.3.3.CO;2-D>CrossRefGoogle Scholar
Ruggeri, M, Lasalvia, A, Dall’Agnola, R, van Wijngaarden, B, Knudsen, HC, Leese, Met al.Development, internal consistency and reliability of the Verona Service Satisfaction Scale--European Version. EPSILON Study 7. European psychiatric services: inputs linked to outcome domains and needs. Br J Psychiatry Suppl 2000;s41–s48.CrossRefGoogle ScholarPubMed
Salomon, L, Gasquet, I, Mesbah, M, Ravaud, PConstruction of a scale measuring inpatients’ opinion on quality of care. Int J Qual Health Care 1999;11:507–516.CrossRefGoogle ScholarPubMed
Samsa, G, Edelman, D, Rothman, ML, Williams, GR, Lipscomb, J, Matchar, DDetermining clinically important differences in health status measures: a general approach with illustration to the Health Utilities Index Mark II. Pharmacoeconomics 1999;15:141–155.CrossRefGoogle ScholarPubMed
SAS. SAS 9.2 Software. 9.2 ed. Cary, NC, USA: SAS Institute Inc; 2002–2008.Google Scholar
Spearing, MK, Post, RM, Leverich, GS, Brandt, D, Nolen, WModification of the Clinical Global Impressions (CGI) Scale for use in bipolar illness (BP): the CGI-BP. Psychiatry Res 1997;73:159–171.CrossRefGoogle ScholarPubMed
Verdoux, H, Begaud, BPharmaco-epidemiology: what do (and don’t) we know about utilisation and impact of psychotropic medications in real-life conditions?. Br J Psychiatry 2004;185:93–94.CrossRefGoogle ScholarPubMed
Voruganti, LN, Awad, AGPersonal evaluation of transitions in treatment (PETiT): a scale to measure subjective aspects of antipsychotic drug therapy in schizophrenia. Schizophr Res 2002;56:37–46.CrossRefGoogle Scholar
Witthaus, E, Stewart, J, Bradley, CTreatment satisfaction and psychological well-being with insulin glargine compared with NPH in patients with type 1 diabetes. Diabet Med 2001;18:619–625.CrossRefGoogle ScholarPubMed
Wolters, HA, Knegtering, H, van den Bosch, RJ, Wiersma, DEffects and side effects of antipsychotic treatment in schizophrenia: pros and cons of available self-rating scales. Schizophr Res 2009;112:114–118.CrossRefGoogle ScholarPubMed
Zwick, WR, Velicer, WFComparison of five rules for determining the number of components to retain. Psychol Bull 1986;99:432–442.CrossRefGoogle Scholar
Submit a response

Comments

No Comments have been published for this article.