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Relationship between metabolic syndrome and functioning in patients with bipolar disorder type 1

Published online by Cambridge University Press:  13 August 2021

Ö. Şahmelikoğlu Onur  and
Ö. Baş Uluyol
Ö. Şahmelikoğlu Onur*
Affiliation:
Psychiatry, Bakirkoy Research & Training Hospital for Psychiatry, Neurology and Neurosurgery, İstanbul, Turkey
Ö. Baş Uluyol
Affiliation:
Psychiatry, Sancaktepe Şehit Prof. Dr. İlhan Varank Research & Training Hospital, İstanbul, Turkey
*
*Corresponding author.

Abstract

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Introduction

The available literature indicates a possible association between metabolic syndrome (MS) which is highly prevalent among patients with bipolar disorder (BD), and functioning.

Objectives

We sought to compare differences in functional areas of patients with Bipolar Disorder Type 1 (BPD-1)with and without MS in euthymic period.

Methods

This study included 69 euthymic BPD-1 patients without MS and 46 age- and sex-matched BPD-1 patients with MS. All participants completed a sociodemographic form; took the Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), Young Mania Rating Scale score, and Bipolar Disorder Functioning Questionnaire. MS was diagnosed according to the International Diabetes Federation (IDF) criteria.

Results

All of the functioning areas were significantly lower in the BPD-1 with MS group than in the without MS group (p < 0.05). Moreover age at onset of disease was significantly lower in BPD-1 group with MS than without MS (p < 0.05). Number of suicide attempts was significantly higher in BPD-1 group with MS than without MS (p < 0.05). Catatonic and melancholic depression were significantly more prevalent in the BPD-1 with MS than without MS (p < 0.05).

Conclusions

Our findings suggest that MS might have an effect on functioning in BD patients even in euthymic period.

Disclosure

No significant relationships.

Keywords

bipolar disorderMetabolic syndromeFunctionality
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S621 - S622
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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