Hostname: page-component-76fb5796d-r6qrq Total loading time: 0 Render date: 2024-04-28T17:38:59.069Z Has data issue: false hasContentIssue false
  • English
  • Français

The relationship of personality traits to substance abuse in patients with bipolar disorder

Published online by Cambridge University Press:  16 April 2020

Gonzalo Haro ,
Joseph R. Calabrese ,
Christina Larsson ,
Edwin R. Shirley ,
Eva Martín ,
Carmen Leal  and
Pedro L. Delgado
Gonzalo Haro*
Affiliation:
Dual Pathology Unit, Psychiatry Department, Hospital de la Ribera, C/Onda, s/n e 46600 Alzira, Valencia, Spain IDYCA, CEU-Cardenal Herrera University, Moncada, Spain
Joseph R. Calabrese
Affiliation:
University Hospitals of Cleveland, Case Western Reserve University, 11400 Euclid Ave, Cleveland, OH44106, USA
Christina Larsson
Affiliation:
Clínica del Sistema Nervioso Central, 111 Primado Reig Ave, 2nd Floor, 46020Valencia, Spain
Edwin R. Shirley
Affiliation:
University Hospitals of Cleveland, Case Western Reserve University, 11400 Euclid Ave, Cleveland, OH44106, USA
Eva Martín
Affiliation:
Department of Psychiatry, Hospital Clínico Universitario of Valencia, 16 Blasco Iba~nez Ave, 46010Valencia, Spain
Carmen Leal
Affiliation:
Department of Psychiatry, Faculty of Medicine, University of Valencia, 17 Blasco Iba~nez Ave, 46010Valencia, Spain
Pedro L. Delgado
Affiliation:
Department of Psychiatry, The University of Texas Health Sciences Center, San Antonio, TX78229-3900, USA
*
*Corresponding author. Dual Pathology Unit, Psychiatry Department, Hospital de la Ribera, C/Onda, s/n – 46600 Alzira, Valencia, Spain. Tel.: +34 636 99 35 09. E-mail address: gharoc@comv.es (G. Haro).
Get access

Abstract

Purpose

The aim of this study is to determine if personality traits contribute to the likelihood of substance abuse in Bipolar Disorder (BD).

Subjects/materials and methods

Fifty-nine patients meeting DSM-IV criteria for BD: 20 without any history of Substance Related Disorder (SRD), 21 with a lifetime history of SRD but without current SRD, and 18 with current SRD. Patients filled out the TCI, the differences were analyzed by ANOVA and the likelihood was obtained by Multinomial Logistic Regression.

Results

Only Novelty Seeking (NS) is statistically different between the groups. Patients with BD with current SRD have higher rates in NS than those with past SRD, and those without a history of SRD. NS was confirmed as a predicting variable, both to current SRD (OR [CI 95%] = 1.039/1.351; p = 0.011) and past SRD (OR [CI 95%] = 1.004/1.277; p = 0.042) on patients with BD.

Discussion

The results shown would appear to confirm the relationship of NS with the SRD, so long as there is no clear evidence that indicates the association of NS with BD.

Conclusions

There appears a greater predisposition to develop SRD in those patients with a higher degree of NS. The use of the Cloninger's TCI could be used in BD to determine the risk of developing an SRD. Early detection might help improve prognosis.

Keywords

Bipolar disorderSubstance related disordersPersonalityCloninger's TCINovelty seeking
Type
Original article
Information
European Psychiatry , Volume 22 , Issue 5 , July 2007 , pp. 305 - 308
Copyright
Copyright © Elsevier Masson SAS 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

1

Tel.: +1 216 844 2875.

2

Tel.: +34 96 369 92 96.

3

Tel.: +34 96 386 26 00.

References

Akiskal, H.S., Akiskal, K.K., Haykal, R.F., Manning, J.S., Connor, P.D.TEMPS-A: progress towards validation of a self-rated clinical version of the temperament evaluation of the Memphis, Pisa, Paris, and San Diego autoquestionnaire. J Affect Disord 2005 Mar;85(1-2) 3–16.CrossRefGoogle ScholarPubMed
Back, D.W., Winokur, G., Bell, S., Nasrallah, A., Hulbert, J.Complicated mania: comorbidity and immediate outcome in the treatment of mania. Arch Gen Psychiatry 1988;45:232–236.Google Scholar
Cloninger, C.R.A unified biosocial theory of personality and its role in the development of anxiety states. Psychiatr Dev 1986;3:167–226.Google Scholar
Cloninger, C.R., Svrakic, D.M., Przybech, T.R.A psychobiological model of temperament and character. Arch Gen Psychiatry 1993;50:975–990.CrossRefGoogle ScholarPubMed
Cohen, C., Perrault, G., Griebel, G., Soubrie, P.Nicotine-associated cues maintain nicotine-seeking behavior in rats several weeks after nicotine withdrawal: reversal by the cannabinoid (CB1) receptor antagonist, rimonabant (SR141716). Neuropsychopharmacology 3012005 Jan 145–155.CrossRefGoogle Scholar
Downey, K.K., Pomerleau, C.S., Pomerleau, O.F.Personality differences related to smoking and adult attention deficit hyperactivity disorders. J Subst Abuse 1996;8:129–135.CrossRefGoogle Scholar
Engstrom, C., Brandstrom, S., Sigvardsson, S., Cloninger, R., Nylander, P.O.Bipolar disorder II: personality and age of onset. Bipolar Disord 2003;5(5):340–348.CrossRefGoogle ScholarPubMed
Flick, S.N., Roy-Byrne, P., Cowley, D.S., Shores, M.M., Dunner, D.L.DSM-III-R personality disorders in mood and anxiety disorders clinic: prevalence, comorbidity, and clinic correlates. J Affect Disord 1993;27:71–79.CrossRefGoogle ScholarPubMed
Feinman, J.A., Dunner, D.L.The effect of alcohol and substance abuse on the course of bipolar affective disorders. J Affect Disord 1996;37:43–49.CrossRefGoogle Scholar
George, E.L., Miklowitz, D.J., Richards, J.A., Simoneau, T.L., Tayolr, D.O.The comorbidity of bipolar disorder and axis II personality disorders: prevalence and clinical correlates. Bipolar Disord 2003 Apr;5(2):115–122.CrossRefGoogle ScholarPubMed
Goodwin, F.K., Jamison, K.R.Personality and interpersonal behavior. Manic depressive illness Oxford University Press; 1990. p. 281–317.Google Scholar
Henry, C., Bellvier, F., Sorbara, F., Tangwongchai, S., Lacoste, J., Faure-Chaigneau, M.et al.Bipolar sensation seeking is associated with a propensity to abuse rather than to temperament characteristics. Eur Psychiatry 2001;16:289–292.CrossRefGoogle Scholar
Hosak, L., Preiss, M., Halir, M., Cermakova, E., Csemy, L.Temperament and character inventory (TCI) personality profile in metamphetamine abusers: a controlled study. Eur Psychiatry 1942004 Jun 193–195.CrossRefGoogle Scholar
Janowsky, D.S., Morter, S., Hong, L., Howe, L.Myers Briggs type indicator and tridimensional personality questionnaire differences between bipolar patients and unipolar depressed patients. Bipolar Disord 1999;2:98–108.CrossRefGoogle Scholar
Kampov-Polevoy, A.B., Eick, C., Boland, G., Khalitov, E., Crews, F.T.Sweet liking, novelty seeking, and gender predict alcoholic status. Alcohol Clin Exp Res 2004 Sep;28(9):1291–1298.CrossRefGoogle ScholarPubMed
Kay, J.H., Altshuler, L.L., Ventura, J., Mintz, J.Prevalence of axis II comorbidity in bipolar patients with and without alcohol use disorders. Annals of Clinical Psychiatry 1999;11(4):187–195.CrossRefGoogle ScholarPubMed
Kessler, R.C., McGonagle, K.A., Zhao, S., Nelson, C.B., Hughes, M., Eshleman, S.et al.Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the national comorbidity survey. Arch Gen Psychiatry 1994;51:8–19.CrossRefGoogle ScholarPubMed
Kawpil, T.R., Miller, M.B., Zinser, M.C., Chapman, L.J., Chapman, J., Eckbland, M.A longitudinal study of high scores on the hypomanic personality scale. J Abnorm Psychol 2000;109(2):222–226.CrossRefGoogle Scholar
Lara, D.R., Pinto, O., Akiskal, K., Akiskal, H.S.Toward an integrative model of the spectrum of mood, behavioural and personality disorders on fear and anger traits: I. Clinical implications. J Affect Disord 2006 Aug;94(1–3)67–87.CrossRefGoogle Scholar
Michel, G., Le Heuzey, M.F., Purper-Ouakil, D., Mouren-Simeoni, M.C.Novelty seeking and risk taking behavior in adolescents. Rev Infirm 2004 Jun;(102):31–34.Google ScholarPubMed
Osher, Y., Cloninger, C.R., Belmaker, R.H.TPQ in euthymic manic-depressive patients. J Psychiatr Res 1996;30(5):353–357.CrossRefGoogle ScholarPubMed
Osher, Y., Lefkifker, E., Kotler, M.Low persistence in euthymic manic-depressive patients: a replication. J Affect Disord 1999;53:87–90.CrossRefGoogle ScholarPubMed
Skinstad, A.H., Swain, A.Comorbidity in a clinical sample of substance abusers. Am J Drug Alcohol Abuse 2001 Feb;27(1):45–64.CrossRefGoogle Scholar
Strakowski, S.M., Tohen, M., Stoll, A.L., Faedda, G.L., Goodwin, D.C.Comorbidity in mania at first hospitalisation. Am J Psychiatry 1992;149:554–556.Google Scholar
Strakowski, S.M., Stoll, A.L., Tohen, M., Faedda, G.L., Goodwin, D.C.The tridimensional personality questionnaire as a predictor of six-month outcome in first episode mania. Psychiatry Res 1992;48:1–8.CrossRefGoogle Scholar
Strakowski, S.M., Keck, P.E., McElroy, S.L., Lonczac, H.S., West, S.A.Chronology of comorbid and principal syndromes in first-episode psychosis. Compr Psychiatry 1995;36:106–112.CrossRefGoogle ScholarPubMed
Strakowski, S.M., Dunayevich, E., Keck, P.E., McElroy, S.L.Affective state dependence of the tridimensional personality questionnaire. Psychiatry Res 1995;57:209–214.CrossRefGoogle ScholarPubMed
Svrakic, D.M., Przybeck, T.R., Cloninger, C.R.Further contribution to the conceptual validity of the unified biosocial model of personality: US and Yugoslav data. Compr Psychiatry 1991;32:195–209.CrossRefGoogle ScholarPubMed
Takata, T., Takaoka, K.Bipolar II disorder and its premorbid personality. Psychopathology 2000;33:86–93.CrossRefGoogle ScholarPubMed
Vieta, E., Colom, F., Corbella, B., Martínez-Arán, A., Reinares, M., Benabarre, A.et al.Clinical correlates of psychiatric comorbidity in bipolar I patients. Bipolar Disord 2001;3:253–258.CrossRefGoogle ScholarPubMed
Vukov, M., Baba-Milkic, N., Lecic, D., Mijalkovic, S., Marinkovic, J.Personality dimensions of opiate addicts. Acta Psychiatr Scand 1995;91:103–107.CrossRefGoogle ScholarPubMed
Wolpe, P.R., Gorton, G., Serota, R., Sanford, B.Predicting compliance of dual diagnoses with aftercare treatment. Hospital and Community Psychiatry 1993;44(1):45–49.Google ScholarPubMed
Young, T.L., Bagby, R.M., Cooke, R.G., Parke, J.D.A., Levitt, A.J., Joffe, R.F.A comparison of tridimensional personality questionnaire dimensions in bipolar disorder and unipolar depression. Psychiatry Res 1995;58:139–143.CrossRefGoogle ScholarPubMed
Submit a response

Comments

No Comments have been published for this article.