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Screnning of viral hepatitis in mental disorder patients: Psiqui-Clinic Programme

Published online by Cambridge University Press:  01 September 2022

M. Cavero ,
T. Planas ,
J. Goikolea ,
S. Lens ,
C. Bartrés ,
L. Colomer ,
C. García ,
M. Valentí ,
V. Ruiz  and
Y. Rivas
...Show all authors
M. Cavero*
Affiliation:
Hospital Clínic, , department Of Psychiatry And Psychology, Barcelona, Spain
T. Planas
Affiliation:
Hospital Clínic, , department Of Psychiatry And Psychology, Barcelona, Spain
J. Goikolea
Affiliation:
Hospital Clínic, , department Of Psychiatry And Psychology, Barcelona, Spain
S. Lens
Affiliation:
Hospital Clínic, , Liver Unit, Barcelona, Spain
C. Bartrés
Affiliation:
Hospital Clínic, , Liver Unit, Barcelona, Spain
L. Colomer
Affiliation:
Hospital Clínic, , department Of Psychiatry And Psychology, Barcelona, Spain
C. García
Affiliation:
Hospital Clínic, , department Of Psychiatry And Psychology, Barcelona, Spain
M. Valentí
Affiliation:
Hospital Clínic, , department Of Psychiatry And Psychology, Barcelona, Spain
V. Ruiz
Affiliation:
Hospital Clínic, , department Of Psychiatry And Psychology, Barcelona, Spain
Y. Rivas
Affiliation:
Hospital Clínic, , department Of Psychiatry And Psychology, Barcelona, Spain
A. Benabarre
Affiliation:
Hospital Clínic, , department Of Psychiatry And Psychology, Barcelona, Spain
R. Catalan
Affiliation:
Hospital Clínic, , department Of Psychiatry And Psychology, Barcelona, Spain
G. Masana
Affiliation:
Hospital Clínic, , department Of Psychiatry And Psychology, Barcelona, Spain
J. Colom
Affiliation:
Agéncia de Salut Pública de Catalunya, Programa Pcavihv, Barcelona, Spain
X. Forns
Affiliation:
Hospital Clínic, , Liver Unit, Barcelona, Spain
R. Martin-Santos
Affiliation:
Hospital Clínic, , department Of Psychiatry And Psychology, Barcelona, Spain
Z. Mariño
Affiliation:
Hospital Clínic, , Liver Unit, Barcelona, Spain
*
*Corresponding author.

Abstract

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Introduction

The WHO would increase diagnosis and treatment of viral hepatitis in the world by 2030, based on the high efficacy of direct-acting-antivirals against HCV, extended vaccination programs in HBC, and epidemiological data. Diagnostic of HCV/HBV infection has been simplified by point-of-care (POC) devices (cheap/easy-to-use/interprete/qick-results), detecting anti-HCV-antibodies or HBV-antigen in capillary blood at the patients´site. The current seroprevalence of viral hepatitis B/C in general population in Spain is 0.5%/1% and would be higher (3-17%) in people with severe-mental-disorder due to risk factors and traditionally less access to health care.

Objectives

To design a screening protocol for HCV eradication and HBV-detection, and risk factors among severe-mental-disorder patients in a CommunityMentalHealthCenter. To guarantee equal access to viral hepatitis screening and therapy among this population.

Methods

Outpatients visited along one-year who accepts participate. Using POC-device for qualitative detection of anti-HCV-antibodies (Quickview-of-Lumiquick-Diagnostics®)/HBsAG (Abbott-Rapid-Diagnostics®). Socio-demographic data; mental disorder(ICD-10); HCV/HBV risk-factors; Neurotoxicity-scale (mood/cognition/sleep/gastrointestinal/sickness/motor); SF-12; Patient-satisfaction. Subjects with positive HCV/HBV POC-test will have a on-site venopuncture to assess hemograme/liver tests, and HCV-RNA (Cobas-TaqMan-RocheDiagnostics)/HBsAg-ELISA (Atellica-Siemens). In positive HCV-RNA (active infection) the psychiatric-team will inform the hepatology-team for non-invasive liver fibrosis assessment and DAA prescription. The patient will receive 8-12-weeks on-site treatment, and assessed (Neurotoxicity/SF-12).HCV cure will be confirmed by HCV-RNA in blood. Chronic-cases will be managed at Hepatology-Unit.

Results

We will present the results of the implementation of the programme and their ability to detect viral-hepatitis-positive cases among patients with severe-mental-disorders and to treat them effectively.

Conclusions

Our results may support the generalisation of the programme in among CMHC’s.

Disclosure

No significant relationships.

Keywords

viral hepatitisHCVSevere Mental DisordersHBC
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S480 - S481
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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