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MARFAN SYNDROME AND PREGNANCY: CLINICAL IMPLICATIONS AND MANAGEMENT

  • ARIADNA C GRIGORIU (a1), JACK COLMAN (a2), CANDICE K SILVERSIDES (a3), RACHEL WALD (a3), SAMUEL C SIU (a4) and MATHEW SERMER (a1)...
Abstract

Marfan syndrome (MFS) is an autosomal dominant connective tissue disorder that affects multiple organ systems, primarily the cardiovascular, ocular and skeletal. It is the most common inherited condition affecting the heart and the aorta, occurring in 1:5000–1:9800 people. There is no ethnic or gender predisposition; 20 to 35% of cases arise from de novo mutations.

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Corresponding author
Mathew Sermer, Mount Sinai Hospital, 600 University Avenue, Room 1007, Toronto, Ontario M5G 1×5, email address: MSermer@mtsinai.on.ca
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Fetal and Maternal Medicine Review
  • ISSN: 0965-5395
  • EISSN: 1469-5065
  • URL: /core/journals/fetal-and-maternal-medicine-review
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