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Gene diversity in finite populations

Published online by Cambridge University Press:  14 April 2009

Naoyuki Takahata
Affiliation:
National Institute of Genetics, Mishima, Shizuoka-ken, 411, Japan
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DNA sequence comparison among homologous genes sampled at random from one or two populations allows one to estimate the ultimate amount of genetic variation maintained in a population and to construct the gene genealogy within and between populations. Moreover, if we use the finding of the molecular clock (Zuckerkandl & Pauling, 1965), it is also possible to estimate the divergence time of populations examined. Such an estimated divergence time is, however, intricately affected by samples and stochastic forces occurring in the course of evolution.

Type
Short Paper
Copyright
Copyright © Cambridge University Press 1985

References

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