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Genetic evidence for restriction targets in the DNA of phages λ and φ 80

  • Naomi C. Franklin (a1) and William F. Dove (a2)

Extract

Temperate phages φ 80 and λ grown in E. coli strain C differ markedly in the degree to which they are restricted by E. coli strain K. The basis of this difference is subject to genetic recombination and deletion. The loss of restriction sensitivity by deletion shows that sensitivity is determined by loci in the phage genome. These loci are interpreted to be targets of the restriction mechanism, in agreement with previous biochemical evidence.

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References

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Genetics Research
  • ISSN: 0016-6723
  • EISSN: 1469-5073
  • URL: /core/journals/genetics-research
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