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Are Clinical Characteristics of Patients with Sepsis Codes Changing over Time?

  • Anica Law (a1) and Michael Klompas (a1) (a2)

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Corresponding author

Address correspondence to Michael Klompas, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 133 Brookline Avenue, 6th Floor, Boston, MA 02215 (mklompas@partners.org).

References

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1. Martin, GS, Mannino, DM, Eaton, S, Moss, M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003;348:15461554.
2. Dombrovskiy, VY, Martin, AA, Sunderram, J, Paz, HL. Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003. Crit Care Med 2007;35:12441250.
3. Hall, MJ, Williams, SN, DeFrances, CJ, Golosinskiy, A. Inpatient care for septicemia or sepsis: a challenge for patients and hospitals. NCHS Data Brief 2011:18.
4. Dellinger, RP, Levy, MM, Rhodes, A, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med 2013;41:580637.
5. Rhee, C, Gohil, S, Klompas, M. Regulatory mandates for sepsis care—reasons for caution. N Engl J Med 2014;370:16731676.
6. Pronovost, P, Needham, D, Berenholtz, S, et al. An intervention to decrease catheter-related bloodstream infections in the ICU. N Engl J Med 2006;355:27252732.
7. Centers for Disease C, Prevention. Vital signs: central line-associated blood stream infections—United States, 2001, 2008, and 2009. MMWR Morb Mortal Wkly Rep 2011;60:243248.
8. Lindenauer, PK, Lagu, T, Shieh, MS, Pekow, PS, Rothberg, MB. Association of diagnostic coding with trends in hospitalizations and mortality of patients with pneumonia, 2003–2009. JAMA 2012;307:14051413.
9. Rivers, E, Nguyen, B, Havstad, S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001;345:13681377.
10. Levy, MM, Rhodes, A, Phillips, GS, et al. Surviving sepsis campaign: association between performance metrics and outcomes in a 7.5-year study. Crit Care Med 2015;43:312.

Are Clinical Characteristics of Patients with Sepsis Codes Changing over Time?

  • Anica Law (a1) and Michael Klompas (a1) (a2)

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