Burdon, DW. Clostridium difficile: the epidemiology and prevention of hospital-acquired infection. Infection
Wüst, J, Sullivan, NM, Hardegger, U, Wilkins, TD. Investigation of an outbreak of antibiotic-associated colitis by various typing methods. J Clin Microbiol
Tabaqchali, S, O'Farrell, S, Holland, D, Silman, R. Typing scheme for Clostridium difficile: its application in clinical and epidemiological studies. Lancet
Johnson, S, Gerding, DN, Olson, MM, Weiler, MD, Hughes, RA, Clabots, CR, et al. Prospective, controlled study of vinyl glove use to interrupt Clostridium difficile nosocomial transmission. Am J Med
McFarland, LV, Mulligan, ME, Kwok, RYY, Stamm, WE. Nosocomial acquisition of Clostridium difficile infection. N Engl J Med
Bowen, KE, McFarland, LV, Greenberg, RN, Ramsey, MM, Record, KE, Svenson, J. Isolation of Clostridium difficile at a university hospital: a two-year study. Clin Infect Dis
1995;20(suppl 2) :S261–S262.
Gerding, DN, Johnson, S, Peterson, LR, Mulligan, ME, Silva, J Jr.
Clostridium difficile-associated diarrhea and colitis. Infect Control Hosp Epidemiol
Fekety, R. Guidelines for the diagnosis and management of Clostridium difficile-associateA diarrhea and colitis. Am J Gastroenterol
Feldman, RJ, Kallich, M, Weinstein, MP
Bacteremia due to Clostridium difficile: case report and review of extraintestinal C difficile infections. Clin Infect Dis
Pron, B, Merckx, J, Touzet, P, Ferroni, A, Poyart, C, Berche, P, et al. Chronic septic arthritis and osteomyelitis in a prosthetic knee joint due to Clostridium difficile
. Eur J Clin Microbiol Infect Dis
Lowenkron, SE, Waxner, J, Khullar, P, Ilowite, JS, Niederman, MS, Fein, AM.
Clostridium difficile infection as a cause of severe sepsis. Intensive Care Med
Fekety, R, McFarland, LV, Surawicz, CM, Greenberg, RN, Elmer, GW, Mulligan, ME. Recurrent Clostridium difficile diarrhea: characteristics of and risk factors for patients enrolled in a prospective, randomized, double-blinded trial. Clin Infect Dis
Qualman, SJ, Petric, M, Karmali, MA, Smith, CR, Hamilton, SR.
Clostridium difficile invasion and toxin circulation in fatal pediatric pseudomembranous colitis. Am J Clin Pathol
Walley, T, Milson, D. Loperamide related toxic megacolon in Clostridium difficile colitis. Postgrad Med J
Riley, TV, Bowman, RA, Carroll, SM. Diarrhea associated with Clostridium difficile in a hospital population. Med J Aust
Yablon, SA, Krotenberg, R, Fruhmann, K.
Clostridium difficile-reiated disease: evaluation and prevalence among inpatients with diarrhea in two freestanding rehabilitation hospitals. Arch Phys Med Rehabil
Pear, SM, Williamson, TH, Bettin, KM, Gerding, DN, Galgiani, JN. Decrease in nosocomial Clostridium difficile-associated diarrhea by restricting clindamycin use. Ann Intern Med
Samore, MH, DeGirolami, PC, Tlucko, A, Lichtenberg, DA, Melvin, ZA, Karchmer, AW.
Clostridium difficile colonization and diarrhea at a tertiary care hospital. Clin Infect Dis
Barbut, F, Corthier, G, Charpak, Y, Cerf, M, Monteil, H, Fosse, T, et al. Prevalence and pathogenicity of Clostridium difficile in hospitalized patients. A French multicenter study. Arch Intern Med
Hirschhorn, LR, Trnka, Y, Onderdonk, A, Lee, M-LT, Platt, R. Epidemiology of community-acquired Clostridium difficile-associated diarrhea. J Infect Dis
McFarland, LV, Surawicz, CM, Greenberg, RN, Fekety, R, Elmer, GW, Moyer, KA, et al. A randomized placebo-controlled trial of Saccharomyces boulardii in combination with standard antibiotics for Clostridium difficile disease. JAMA
Liacouras, CA, Piccoli, DA. Whole-bowel irrigation as an adjunct to the treatment of chronic, relapsing Clostridium difficile colitis. J Clin Gastroenterol
Tvede, M, Rask-Madsen, J. Bacteriotherapy for chronic relapsing Clostridium difficile diarrhoea in six patients. Lancet
Tedesco, FJ, Gordon, D, Fortson, WC. Approach to patients with multiple relapses of antibiotic-associated pseudomembranous colitis. Am J Gastroenterol
Biller, JA, Katz, AJ, Flores, AF, Buie, TM, Gorbach, SL. Treatment of recurrent Clostridium difficile colitis with Lactobacillus GG. J Pediatr Gastroenterol Nutr
Walters, BAJ, Roberts, R, Stafford, R, Seneviratne, E. Recurrence of antibiotic associated colitis: endogenous persistence of C difficile during vancomycin therapy. Gut
Clostridium difficile: history of its role as an enteric pathogen and the current state of knowledge about the organism. Clin Infect Dis
George, WL, Volpicelli, NA, Stiner, DB, Richman, DD, Liechty, EJ, Mok, HYI, et al. Relapse of pseudomembranous colitis after vancomycin therapy. N Engl J Med
Tarlov, AR, Ware, JE Jr, Greenfield, S, Nelson, EC, Perrin, E, Zubkoff, M. The medical outcomes study. An application of methods for monitoring the results of medical care. JAMA
Johnson, LL, McFarland, LV, Dearing, P, Raisys, V, Schoenknect, FD. Identification of Clostridium difficile in stool specimens by culture-enhanced gas-liquid chromatography. J Clin Microbiol
Willey, SH, Bartlett, JG. Cultures for Clostridium difficile in stools containing a cytotoxin neutralized by Clostridium sordellii antitoxin. J Clin Microbiol
De Girolami, PC, Hanff, PA, Eichelberger, K, Longhi, L, Teresa, H, Pratt, J, et al. Multicenter evaluation of a new enzyme immunoassay for detection of Clostridium difficile enterotoxin A. J Clin Microbiol
Borriello, SP, Vale, T, Brazier, JS, Hyde, S, Chippeck, E. Evaluation of a commercial enzyme immunoassay kit for the detection of Clostridium difficile toxin A. Eur J Clin Microbiol Infect Dis
Doern, GV, Coughlin, RT, Wu, L. Laboratory diagnosis of Clostridium difficile-associated gastrointestinal disease: comparison of a monoclonal antibody enzyme immunoassay for toxins A and B with a monoclonal antibody enzyme immunoassay for toxin A only and two cytotoxicity assays. J Clin Microbiol
Yannelli, B, Gurevich, I, Schoch, P, Cunha, BA. Yield of stool cultures, ova and parasite tests, and Clostridium difficile determinations in nosocomial diarrheas. Am J Infect Control
Siegel, DL, Edelstein, PH, Nachamkin, I. Inappropriate testing for diarrheal diseases in the hospital. JAMA
Thompson, JS, Hodge, DS, Borczyk, AA.
Rapid biochemical test to identify verocytotoxin-positive strains of E coli serotype 0157. J Clin Microbiol
Nath, SK, Thornley, JH, Kelly, M, Kucera, B, On, SLW, Holmes, B, et al. A sustained outbreak of Clostridium difficile in a general hospital: persistence of a toxigenic clone in four units. Infect Control Hosp Epidemiol
Olson, MM, Shanholtzer, CJ, Lee, JT Jr, Gerding, DN. Ten years of prospective Clostridium difficile-associated disease surveillance and treatment at the Minneapolis VA Medical Center, 1982-1991. Infect Control Hosp Epidemiol
Kofsky, P, Rosen, L, Reed, J, Tolmie, M, Ufberg, D.
Clostridium difficile-a common and costly colitis. Dis Colon Rectum
McFarland, LV, Surawicz, CM, Stamm, WE. Risk factors for Clostridium difficile carriage and C difficile-associated diarrhea in a cohort of hospitalized patients. J Infect Dis
Eriksson, S, Aronsson, B. Medical implications of nosocomial infection with Clostridium difficile
. Scand J Infect Dis
Wenisch, C, Parschalk, B, Hasenhündl, M, Hirschl, AM, Graninger, W. Comparison of vancomycin, teicoplanin, metronidazole, and fusidic acid for the treatment of Clostridium difficile-associated diarrhea. Clin Infect Dis
Teasley, DG, Gerding, DN, Olson, MM, Peterson, LR, Gebhard, RL, Schwartz, MJ, et al. Prospective randomised trial of metronidazole versus vancomycin for Clostridium difficile-associated diarrhoea and colitis. Lancet
Nelson, DE, Auerbach, SB, Baltch, AL, Desjardin, E, Beck-Sague, C, Rheal, C, et al. Epidemie Clostridium difficile-associated diarrhea: role of second- and third-generation cephalosporins. Infect Control Hosp Epidemiol
Lai, KK, Melvin, ZS, Menard, MJ, Kotilainen, HR, Baker, S.
Clostridium difficile-associated diarrhea: epidemiology, risk factors, and infection control. Infect Control Hosp Epidemiol
Brown, EB, Talbot, GH, Axelrod, P, Provencher, M, Hoegg, C. Risk factors for Clostridium difficile toxin-associated diarrhea. Infect Control Hosp Epidemiol
Zimmerman, RK. Risk factors for Clostridium difficile cytotoxin-positive diarrhea after control for horizontal transmission. Infect Control Hosp Epidemiol
Impallomeni, M, Galletly, NP, Wort, SJ, Starr, JM, Rogers, TR. Increased risk of diarrhoea caused by Clostridium difficile in elderly patients receiving cefotaxime. BMJ
Ehrenpreis, ED, Lievens, MW, Craig, RM.
Clostridium difficile-associated diarrhea after norfloxacin. J Clin Gastroenterol
McFarland, LV, Bauwens, JE, Melcher, SA
Surawicz, CM, Greenberg, RN, Elmer, GW. Ciprofloxacin-associated Clostridium difficile disease. Lancet
Surawicz, CM, McFarland, LV, Elmer, G, Chinn, J. Treatment of recurrent Clostridium difficile colitis with vancomycin and Saccharomyces boulardii
. Am J Gastroenterol
Ariano, RE, Zhanel, GG, Harding, GKM. The role of anion-exchange resins in the treatment of antibiotic-associated pseudomembranous colitis. Can Med Assoc J
Fekety, R, Silva, J, Kauffman, C, Buggy, B, Deery, HG. Treatment of antibiotic-associated Clostridium difficile colitis with oral vancomycin: comparison of two dosage regimens. Am J Med
Larson, HE, Borriello, SP. Quantitative study of antibiotic-induced susceptibility to Clostridium difficile enterocecitis in hamsters. Antimicrob Agents Chemother
Gonzoles, R, Steiner, JF, Sande, MA.
Antibiotic prescribing for adults with colds, upper respiratory tract infection, and bronchitis in ambulatory care physicians. JAMA
Schwartz, B, Bell, DM, Hughes, JM. Preventing the emergence of antimicrobial resistance. A call for action by clinicians, public health officials and patients. JAMA
Hueston, WJ. Antibiotics: neither cost effective nor ‘cough’ effective. J Fam Pract