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Trends in Hospitalization for Community-Associated Methicillin-Resistant Staphylococcus aureus in New York City, 1997–2006: Data from New York State's Statewide Planning and Research Cooperative System

  • Amanda M. Farr (a1), Brandon Aden (a2), Don Weiss (a3), Denis Nash (a4) and Melissa A. Marx (a5)...

To describe trends in hospitalizations with community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection in New York City over 10 years and to explore the demographics and comorbidities of patients hospitalized with CA-MRSA infections.


Retrospective analysis of hospital discharges from New York State's Statewide Planning and Research Cooperative System database from 1997 to 2006.


All patients greater than 1 year of age admitted to New York hospitals with diagnosis codes indicating MRSA who met the criteria for CA-MRSA on the basis of admission information and comorbidities.


We determined hospitalization rates and compared demographics and comorbidities of patients hospitalized with CA-MRSA versus those hospitalized with all other non-MRSA diagnoses by multivariable logistic regression.


Of 18,226 hospitalizations with an MRSA diagnosis over 10 years, 3,579 (20%) were classified as community-associated. The CA-MRSA hospitalization rate increased from 1.47 to 10.65 per 100,000 people overall from 1997 to 2006. Relative to non-MRSA hospitalizations, men, children, Bronx and Manhattan residents, the homeless, patients with human immunodeficiency virus (HIV) infection, and persons with diabetes had higher adjusted odds of CA-MRSA hospitalization.


The CA-MRSA hospitalization rate appeared to increase between 1997 and 2006 in New York City, with residents of the Bronx and Manhattan, men, and persons with HIV infection or diabetes at increased odds of hospitalization with CA-MRSA. Further studies are needed to explore how changes in MRSA incidence, access to care, and other factors may have impacted these rates.

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1. M Barber . Naturally occurring methicillin-resistant staphylococci. J Gen Microbiol 1964;35:183190.

2. L Saravolatz , N Markowitz . Methicillin-resistant Staphylococcus aureus: epidemiologic observations during a community-acquired outbreak. Ann Int Med 1982;96(1):1116.

3. B Herold , L Immergluck , MC Marañan , et al.Community-acquired methicillin-resistant Staphylococcus aureus in children with no identified predisposing risk factor. JAMA 1998;279: 593598.

5. SL Kaplan , KG Hulten , BE Gonzalez , et al.Three-year surveillance of community-acquired Staphylococcus aureus infections in children. Clin Infect Dis 2005;40:17851791.

6. EM Begier , K Frenette , NL Barrett , et al.A high-morbidity outbreak of methicillin-resistant Staphylococcus aureus among players on a college football team, facilitated by cosmetic body shaving and turf burns. Clin Infect Dis 2004;39:14461453.

7. FD Lowy , AE Aiello , M Bhat , et al.Staphylococcus aureus colonization and infection in New York State prisons. J Infect Dis 2007;196:911918.

11. CR Frei , BR Makos , KR Daniels , CU Oramasionwu . Emergence of community-acquired methicillin-resistant Staphylococcus aureus skin and soft tissue infections as a common cause of hospitalization in United States children. J Pediatr Surg 2010;45: 19671974.

15. RM Klevens , MA Morrison , J Nadle , et al.Invasive methicillin-resistant Staphylococcus aureus infections in the United States. JAMA 2007;298:17631771.

16. S Fridkin , J Hageman , M Morrison , et al.Methicillin-resistant Staphylococcus aureus disease in three communities. N Engl J Med 2005;352:14361444.

19. DM Young , HW Harris , ED Charlebois , et al.An epidemic of methicillin-resistant Staphylococcus aureus soft tissue infections among medically underserved patients. Arch Surg 2004; 139: 947951; discussion, 951-953.

20. BW Frazee , J Lynn , ED Charlebois , L Lambert , D Lowery , F Perdreau-Remington . High prevalence of methicillin-resistant Staphylococcus aureus in emergency department skin and soft tissue infections. Ann Emerg Med 2005;45:311320.

21. G Turabelidze , M Lin , B Wolkoff , D Dodson , S Gladbach , BP Zhu . Personal hygiene and methicillin-resistant Staphylococcus aureus infection. Emerg Infect Dis 2006;12:422427.

22. DM Nguyen , L Mascóla , E Brancoft . Recurring methicillin-resistant Staphylococcus aureus infections in a football team. Emerg Infect Dis 2005;11:526532.

25. BA Diep , HF Chambers , CJ Graber , et al.Emergence of multidrug-resistant, community-associated, methicillin-resistant Staphylococcus aureus clone USA300 in men who have sex with men. Ann Intern Med 2008;148:249257.

26. NF Crum-Cianflone , AA Burgi , BR Hale . Increasing rates of community-acquired methicillin-resistant Staphylococcus aureus infections among HIV-infected persons. Int J STD AIDS 2007; 18:521526.

27. TT Trinh , WR Short , LA Mermel . Community-associated methicillin-resistant Staphylococcus aureus skin and soft-tissue infection in HIV-infected patients. J Int Assoc Physicians AIDS Care (Chic) 2009;8:176180.

28. WC Mathews , JC Caperna , RE Barber , et al.Incidence of and risk factors for clinically significant methicillin-resistant Staphylococcus aureus infection in a cohort of HIV-infected adults. J Acquir Immune Defic Syndr 2005;40:155160.

29. BM Coldiron , PR Bergstresser . Prevalence and clinical spectrum of skin disease in patients infected with human immunodeficiency virus. Arch Dermatol 1989;125:357361.

30. KJ Smith , HG Skelton , J Yeager , et al; Military Medical Consortium for the Advancement of Retroviral Research. Cutaneous findings in HIV-1-positive patients: a 42-month prospective study. J Am Acad Dermatol 1994;31:746754.

31. R Rubinstein , AM Genaro , A Motta , G Cremaschi , MR Wald . Impaired immune responses in streptozotocin-induced type I diabetes in mice: involvement of high glucose. Clin Exp Immunol 2008;154:235246.

32. BR Shah , JE Hux . Quantifying the risk of infectious diseases for people with diabetes. Diabetes Care 2003;26:510513.

34. KK Byrd , RC Holman , MG Bruce , et al.Methicillin-resistant Staphylococcus aureus-associated hospitalizations among the American Indian and Alaska Native population. Clin Infect Dis 2009;49:10091015.

35. JC Herigon , AL Hersh , JS Gerber , TE Zaoutis , JG Newland . Antibiotic management of Staphylococcus aureus infections in US children's hospitals, 1999-2008. Pediatrics 2011;125: e1294e1300.

36. AR Caffrey , BJ Quilliam , KL LaPlante . Comparative effectiveness of linezolid and vancomycin among a national cohort of patients infected with methicillin-resistant Staphylococcus aureus. Anrí-microb Agents Chemother 2010;54:43944400.

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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
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