1.Siegel JD, Rhinehart E, Jackson M, et al.2007 Guideline for isolation precautions: preventing transmission of infectious agents in health care settings. Am J Infect Control 2007;35(10suppl 2):S65–S164.
2.Centers for Disease Control and Prevention. Public Health Service statement on management of occupational exposure to human immunodeficiency virus, including considerations regarding zidovudine postexposure use. MMWR Recomm Rep 1990; 39(RR-1):1–14.
3.Centers for Disease Control and Prevention. Update: provisional Public Health Service recommendations for chemoprophylaxis after occupational exposure to HIV. MMWR Morb Mortal Wkly Rep 1996;45(22):468–480.
4.Centers for Disease Control and Prevention. Public Health Service guidelines for the management of health-care worker exposures to HIV and recommendations for postexposure prophylaxis. MMWR Recomm Rep 1998;47(RR-7):1–33.
5.Centers for Disease Control and Prevention. Updated U.S. Public Health Service guidelines for the management of occupational exposures to HBV, HCV, and HIV and recommendations for postexposure prophylaxis. MMWR Recomm Rep 2001;50(RR-11):1–52.
6.Panlilio AL, Cardo DM, Grohskopf LA, Heneine W, Ross CS; US Public Health Service. Updated U.S. Public Health Service guidelines for the management of occupational exposures to HIV and recommendations for postexposure prophylaxis. MMWR Recomm Rep 2005;54(RR-9):1–17.
7.Advisory Committee on Immunization Practices, Centers for Disease Control and Prevention. Immunization of health-care personnel: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2011; 60(RR-7):1–45.
8.Smith DK, Grohskopf LA, Black RJ, et al; US Department of Health and Human Services. Antiretroviral postexposure prophylaxis after sexual, injection-drug use, or other nonoccupational exposure to HIV in the United States: recommendations from the U.S. Department of Health and Human Services. MMWR Recomm Rep 2005;54(RR-2):1–20.
9.Havens PL; American Academy of Pediatrics Committee on Pediatric AIDS. Postexposure prophylaxis in children and adolescents for nonoccupational exposure to human immunodeficiency virus. Pediatrics 2003;111(6 pt 1):1475–1489.
10.Panel on Treatment of HIV-infected Pregnant Women and Prevention of Perinatal Transmission. Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States, http://aidsinfo.nih.gov/contentfiles/lvguidelines/PerinatalGL.pdf. Published 2012. Accessed August 23, 2012.
11.Bell DM. Occupational risk of human immunodeficiency virus infection in healthcare workers: an overview. Am J Med 1997; 102(5B):9–15.
12.Centers for Disease Control and Prevention. The National Surveillance System for Healthcare Workers (NaSH): Summary Report for Blood and Body Fluid Exposure Data Collected from Participating Healthcare Facilities (June 1995 through December 2007). Washington, DC: US Department of Health and Human Services, 2011.
13.Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention. Healthcare Infection Control Practices Advisory Committee (HICPAC): Meeting Summary Report, November 3-4, 2011, Washington, DC. http://www.cdc.gov/maso/FACM/pdfs/HICPAC/2011110304_HICPAC_MINUTES.pdf. Washington, DC: US Department of Health and Human Services, 2011. Accessed March 2013. 14.Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention. Healthcare Infection Control Practices Advisory Committee (HICPAC): Meeting Summary Report, June 14-15, 2012, Atlanta, GA. http://www.cdc.gov/maso/FACM/pdfs/HICPAC/2012061415_HICPAC_MINUTES.pdf. Washington, DC: Department of Health and Human Services, 2012. Accessed March 2013.
15.Wahn V, Kramer HH, Voit T, Brüster HT, Scrampical B, Scheid A. Horizontal transmission of HIV infection between two siblings. Lancet 1986;2(8508):694.
16.Transmission of HIV by human bite. Lancet 1987;2(8557):522.
17.Richman KM, Rickman LS. The potential for transmission of human immunodeficiency virus through human bites. J Acquir Immune Defic Syndr 1993;6(4):402–406.
18.Vidmar L, Poljak M, Tomazic J, Seme K, Klavs I. Transmission of HIV-1 by human bite. Lancet 1996;347(9017):1762.
19.Deshpande AK, Jadhav SK, Bandivdekar AH. Possible transmission of HIV infection due to human bite. AIDS Res Ther 2011;8:16.
20.Andreo SM, Barra LA, Costa LJ, Sucupira MC, Souza IE, Diaz RS. HIV type 1 transmission by human bite. AIDS Res Hum Retroviruses 2004;20(4):349–350.
21.Ippolito G, Puro V, De Carli G; Italian Study Group on Occupational Risk of HIV infection. The risk of occupational human immunodeficiency virus infection in health care workers: Italian multicenter study. Arch Intern Med 1993;153(12):1451–1458.
22.Cardo DM, Culver DH, Ciesielski CA, et al; Centers for Disease Control and Prevention Needlestick Surveillance Group. A case-control study of HIV seroconversion in health care workers after percutaneous exposure. N Engl J Med 1997;337(21):1485–1490.
23.Mast ST, Woolwine JD, Gerberding JL. Efficacy of gloves in reducing blood volumes transferred during simulated needle-stick injury. J Infect Dis 1993;168(6):1589–1592.
24.Furtado MR, Callaway DS, Phair JP, et al.Persistence of HIV-1 transcription in peripheral-blood mononuclear cells in patients receiving potent antiretroviral therapy. N Engl J Med 1999; 340(21):1614–1622.
25.Ibáñez A, Puig T, Elias J, Clotet B, Ruiz L, Martinez MA. Quantification of integrated and total HIV-1 DNA after long-term highly active antiretroviral therapy in HIV-1-infected patients. AIDS 1999;13(9):1045–1049.
26.Stürmer M, Doerr HW, Berger A, Gute P. Is transmission of HIV-1 in non-viraemic serodiscordant couples possible? Antivir Ther 2008;13(5):729–732.
27.Tubiana R, Le Chenadec J, Rouzioux C, et al.Factors associated with mother-to-child transmission of HIV-1 despite a maternal viral load < 500 copies/ml at delivery: a case-control study nested in the French perinatal cohort (EPF-ANRS COI). Clin Infect Dis 2010;50(4):585–596.
29.Shih CC, Kaneshima H, Rabin L, et al.Postexposure prophylaxis with zidovudine suppresses human immunodeficiency virus type 1 infection in SCID-hu mice in a time-dependent manner. J Infect Dis 1991;163(3):625–627.
30.Tsai CC, Emau P, Follis KE, et al.Effectiveness of postinoculation (R)-9-(2-phosphonylmethoxypropyl)adenine treatment for prevention of persistent simian immunodeficiency virus SIVmine infection depends critically on timing of initiation and duration of treatment. J Virol 1998;72(5):4265–4273.
31.Henderson DK. Human immunodeficiency virus in health care settings. In: Mandeli GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. New York: Elsevier, 2009:3753–3770.
32.Wang SA, Panlilio AL, Doi PA, White AD, Stek M Jr, Saah A. Experience of healthcare workers taking postexposure prophylaxis after occupational HIV exposures: findings of the HIV Postexposure Prophylaxis Registry. Infect Control Hosp Epidemiol 2000;21(12):780–785.
33.Swotinsky RB, Steger KA, Sulis C, Snyder S, Craven DE. Occupational exposure to HIV: experience at a tertiary care center. / Occup Environ Med 1998;40(12):1102–1109.
34.Parkin JM, Murphy M, Anderson J, El-Gadi S, Forster G, Pinching AJ. Tolerability and side-effects of post-exposure prophylaxis for HIV infection. Lancet 2000;355(9205):722–723.
35.Puro V. Post-exposure prophylaxis for HIV infection: Italian Registry of Post-Exposure Prophylaxis. Lancet 2000;355(9214):1556–1557.
36.Lee LM, Henderson DK. Tolerability of postexposure antiretroviral prophylaxis for occupational exposures to HIV. Drug Saf 2001;24(8):587–597.
37.Russi M, Buitrago M, Goulet J, et al.Antiretroviral prophylaxis of health care workers at two urban medical centers. J Occup Environ Med 2000;42(11):1092–1100.
38.Garb JR. One-year study of occupational human immunodeficiency virus postexposure prophylaxis. J Occup Environ Med 2002;44(3):265–270.
39.Grime PR, Ris L, Binns C, Carruthers JR, Williams S. Pan-Thames survey of occupational exposure to HIV and the use of post-exposure prophylaxis in 71 NHS trusts. J Infect 2001;42(l):27–32.
40.Puro V, DeCarli G, Soldani F, et al.Adverse drug reactions associated with PEP. Presented at: 10th Conference on Retroviruses and Opportunistic Infections, 2003, Boston. Poster 711.
41.Beltrami EM, Cheingsong R, Heneine WM, et al; Occupational HIV Exposure Study Group. Antiretroviral drug resistance in human immunodeficiency virus-infected source patients for occupational exposures to healthcare workers. Infect Control Hosp Epidemiol 2003;24(10):724–730.
42.Johnson VA, Calvez V, Günthard HF, et al.2011 Update of the drug resistance mutations in HIV-1. Top Antivir Med 2011;19(4):156–164.
43.Hawkins DA, Asboe D, Barlow K, Evans B. Seroconversion to HIV-1 following a needlestick injury despite combination postexposure prophylaxis. J Infect 2001;43(1):12–15.
44.Beltrami EM, Luo CC, de la Torre N, Cardo DM. Transmission of drug-resistant HIV after an occupational exposure despite postexposure prophylaxis with a combination drug regimen. Infect Control Hosp Epidemiol 2002;23(6):345–348.
45.Perdue B, Wolfe Rufael D, Mellors J, Quinn T, Margolick J. HIV-1 transmission by a needle-stick injury despite rapid initiation of four-drug postexposure prophylaxis. Presented at: 6th Conference on Retroviruses and Opportunistic Infections, 1999, Chicago.
46.Lockman S, Creek T. Acute maternal HIV infection during pregnancy and breast-feeding: substantial risk to infants. J Infect Dis 2009;200(5):667–669.
47.Kourtis AP. Antiretroviral drug use during pregnancy and risk of premature delivery: is there a connection? J Infect Dis 2010; 201(7):978–980.
48.Sarner L, Fakoya A. Acute onset lactic acidosis and pancreatitis in the third trimester of pregnancy in HIV-1 positive women taking antiretroviral medication. Sex Transm Infect 2002;78(1):58–59.
49.Mandelbrot L, Kermarrec N, Marcollet A. Case report: nucleoside analogue-induced lactic acidosis in the third trimester of pregnancy. AIDS 2003;17(2):272–273.
50.Antiretroviral Pregnancy Registry Steering Committee. Antiretroviral Pregnancy Registry International Interim Report for 1 January 1989 through 31 July 2011. Wilmington, NC: Registry Coordinating Center, 2011.
51.Ford N, Calmy A, Mofenson L. Safety of efavirenz in the first trimester of pregnancy: an updated systematic review and metaanalysis. AIDS 2011;25(18):2301–2304.
52.Blanche S, Tardieu M, Benhammou V, Warszawski J, Rustin P. Mitochondrial dysfunction following perinatal exposure to nucleoside analogues. AIDS 2006;20(13):1685–1690.
53.Thorne C, Newell ML. Safety of agents used to prevent mother-to-child transmission of HIV: is there any cause for concern? Drug Sef 2007;30(3):203–213.
54.Mirochnick M, Thomas T, Capparelli E, et al.Antiretroviral concentrations in breast-feeding infants of mothers receiving highly active antiretroviral therapy. Antimicrob Agents Chemother 2009;53(3):1170–1176.
55.Benaboud S, Pruvost A, Coffie PA, et al.Concentrations of tenofovir and emtricitabine in breast milk of HIV-1-infected women in Abidjan, Cote d'Ivoire, in the ANRS 12109 TEmAA study, step 2. Antimicrob Agents Chemother 2011;55(3):1315–1317.
56.Shapiro RL, Hughes MD, Ogwu A, et al.Antiretroviral regimens in pregnancy and breast-feeding in Botswana. N Engl J Med 2010;362(24):2282–2294.
57.Dryden-Peterson S, Shapiro RL, Hughes MD, et al.Increased risk of severe infant anemia after exposure to maternal HAART, Botswana. J Acquir Immune Defic Syndr 2011;56(5):428–436.
58.Humphrey JH, Marinda E, Mutasa K, et al; ZVITAMBO Study Group. Mother to child transmission of HIV among Zimbabwean women who seroconverted postnatally: prospective cohort study. BMJ 2010;341:c6580.
59.Panlilio AL, Sinkowitz-Cochran R, Grady MA, Cardo DM, et al.Barriers to and facilitators of implementing U.S. Public Health Service (PHS) guidelines on occupational exposure management by emergency physicians. Presented at: 13th Annual Meeting of the Society for Healthcare Epidemiology of America, 2003, Arlington, VA. Abstract 240.
60.Masciotra S, McDougal JS, Feldman J, Sprinkle P, Wesolowski L, Owen SM. Evaluation of an alternative HIV diagnostic algorithm using specimens from seroconversion panels and persons with established HIV infections. J Clin Virol 201l;52(suppl 1):S17–S22.
61.Branson BM. The future of HIV testing. J Acquir Immune Defic Syndr 2010;55(suppl 2):S102–S105.
62.Chavez P, Wesolowski L, Patel P, Delaney K, Owen SM. Evaluation of the performance of the Abbott ARCHITECT HIV Ag/Ab combo assay. J Clin Virol 2011;52(suppl 1):S51–S55.
63.Often RA, Smith DK, Adams DR, et al.Efficacy of postexposure prophylaxis after intravaginal exposure of pig-tailed macaques to a human-derived retrovirus (human immunodeficiency virus type 2). J Virol 2000;74(20):9771–9775.
64.Tsai CC, Follis KE, Sabo A, et al.Prevention of SIV infection in macaques by (R)-9-(2-phosphonylmethoxypropyl)adenine. Science 1995;270(5239):1197–1199.
65.Gulick RM, Mellors JW, Havlir D, et al.Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy. N Engl J Med 1997;337(ll):734–739.
66.Hirsch M, Steigbigel R, Staszewski S, et al.A randomized, controlled trial of indinavir, zidovudine, and lamivudine in adults with advanced human immunodeficiency virus type 1 infection and prior antiretroviral therapy. J Infect Dis 1999;180(3):659–665.
67.Wheeler WH, Ziebell RA, Zabina H, et al; Variant, Atypical, and Resistant HIV Surveillance Group. Prevalence of transmitted drug resistance associated mutations and HIV-1 subtypes in new HIV-1 diagnoses, U.S.—2006. AIDS 2010;24(8):1203–1212.
68.Kim D, Wheeler W, Ziebell R, et al.Prevalence of transmitted antiretroviral drug resistance among newly-diagnosed HIV-1-infected persons, US, 2007. Presented at: CROI 2010: 17th Conference on Retroviruses and Opportunistic Infections, 2010, San Francisco.
69.Scherzer R, Estrella M, Li Y, et al.Association of tenofovir exposure with kidney disease risk in HIV infection. AIDS 2012; 26(7):867–875.
70.Cattelan AM, Erne E, Salatino A, et al.Severe hepatic failure related to nevirapine treatment. Clin Infect Dis 1999;29(2):455–456.
71.Johnson S, Baraboutis JG. Adverse effects associated with use of nevirapine in HIV postexposure prophylaxis for 2 health care workers. JAMA 2000;284(21):2722–2723.
72.Centers for Disease Control and Prevention. Serious adverse events attributed to nevirapine regimens for postexposure prophylaxis after HIV exposures—worldwide, 1997-2000. MMWR Morb Mortal Wkly Rep 2001;49(51-52):1153–1156.
73.Armstrong K, Görden R, Santorella G. Occupational exposure of health care workers (HCWs) to human immunodeficiency virus (HIV); stress reactions and counseling interventions. Soc Work Health Care 1995;21(3):61–80.
74.Meienberg F, Bucher HC, Sponagel L, Zinkernagel C, Gyr N, Battegay M. Anxiety in health care workers after exposure to potentially HIV-contaminated blood or body fluids. Swiss Med Wkly 2002; 132 (23-24):321–324.
75.Bentsen C, McLaughlin L, Mitchell E, et al.Performance evaluation of the Bio-Rad Laboratories GS HIV Combo Ag/Ab EIA, a 4th generation HIV assay for the simultaneous detection of HIV p24 antigen and antibodies to HIV-1 (groups M and O) and HIV-2 in human serum or plasma. J Clin Virol 2011; 52(suppl 1):S57–S61.
76.Ridzon R, Gallagher K, Ciesielski C, et al.Simultaneous transmission of human immunodeficiency virus and hepatitis C virus from a needle-stick injury. N Engl J Med 1997;336(13):919–922.
77.Ciesielski CA, Metler RP. Duration of time between exposure and seroconversion in healthcare workers with occupationally acquired infection with human immunodeficiency virus. Am J Med 1997;102(5B):115–116.