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Deterioration of basic activities of daily living and their impact on quality of life across different cognitive stages of dementia: a European study

Published online by Cambridge University Press:  01 May 2014

Clarissa M. Giebel ,
Caroline Sutcliffe ,
Minna Stolt ,
Staffan Karlsson ,
Anna Renom-Guiteras ,
Maria Soto ,
Hilde Verbeek ,
Adelaida Zabalegui  and
David Challis
Clarissa M. Giebel*
Affiliation:
School of Psychological Sciences, University of Manchester, Manchester, UK Personal Social Services Research Unit, University of Manchester, Manchester, UK
Caroline Sutcliffe
Affiliation:
Personal Social Services Research Unit, University of Manchester, Manchester, UK
Minna Stolt
Affiliation:
Department of Nursing Science, University of Turku, Turku, Finland
Staffan Karlsson
Affiliation:
Department of Health Sciences, Lund University, Lund, Sweden
Anna Renom-Guiteras
Affiliation:
School of Nursing Science, Faculty of Health, University of Witten/Herdecke, Witten, Germany
Maria Soto
Affiliation:
Department of Geriatric Medicine, Gerontopole, INSERM 1027, University Hospital de Toulouse, Toulouse, France
Hilde Verbeek
Affiliation:
Department of Health Services Research, Maastricht University, Maastricht, the Netherlands
Adelaida Zabalegui
Affiliation:
Hospital Clinic de Barcelona, Barcelona, Spain
David Challis
Affiliation:
Personal Social Services Research Unit, University of Manchester, Manchester, UK
*
Correspondence should be addressed to: Clarissa M. Giebel, Personal Social Services Research Unit, University of Manchester, Dover Street Building, Oxford Road, M13 9PL Manchester, UK. Phone: +44-161-2755652; Fax: +44-161-2755790. Email: clarissa.giebel@manchester.ac.uk.
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Abstract

Background:

Performing basic activities of daily living (ADLs) is one of the major difficulties encountered in dementia, which can have considerable negative impacts on the quality of life (QoL) of people with dementia (PwD). However, the extent to which basic ADL performance deteriorates across mild, moderate, and severe dementia is little examined and its impact, together with depression and neuropsychiatric behavior, upon QoL, is of considerable relevance across European countries.

Methods:

Data were drawn from people living in the community who were participants in a large-scale European study on transition from community living to care homes of PwD. PwD completed measures on cognitive functioning and QoL, and informal carers reported upon QoL, depressive symptomatology, psychopathology, and functional ability of the PwD.

Results:

ADL performance deteriorated differently for each activity. In particular, toileting, transfer, and feeding remained relatively intact throughout, whereas performance on bathing and dressing deteriorated to a greater extent from mild to severe dementia. It appears that continence was not affected by the stage of dementia with similar levels of impairment. Basic ADL performance impacted to different degrees on QoL across dementia stages and countries.

Conclusions:

Interventions aimed at maintaining independence or QoL need to target different ADLs across different dementia stages and perhaps also tailor interventions to the context of different countries. Findings contribute to the development of non-pharmaceutical interventions and governmental pledges to promote independence in dementia.

Keywords

activities of daily livingdementiaquality of lifecarersdepression
Type
Research Article
Information
International Psychogeriatrics , Volume 26 , Issue 8 , August 2014 , pp. 1283 - 1293
Copyright
Copyright © International Psychogeriatric Association 2014 

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References

Alexopoulus, G. S., Abrams, R. S., Young, R. C. and Shamoian, C. A. (1988). Cornell scale for depression in dementia. Biological Psychiatry, 23, 271–284.CrossRefGoogle Scholar
Andersen, C., Wittrup-Jensen, K., Lolk, A., Andersen, K. and Kragh-Sorensen, P. (2004). Ability to perform activities of daily living is the main factor affecting quality of life in patients with dementia. Health and Quality of Life Outcomes, 2, 52.CrossRefGoogle ScholarPubMed
Auer, S. and Reisberg, B. (1997). The GDS/FAST staging system. International Psychogeriatrics, 9 (Suppl. 1), 167–171.CrossRefGoogle Scholar
Beaunieux, H., Eustache, F., Busson, P., de la Sayette, V., Viader, F. and Desgranges, B. (2009). Cognitive procedural learning in early Alzheimer's disease: impaired processes and compensatory mechanisms. Journal of Neuropsychology, 6, 31–42.CrossRefGoogle ScholarPubMed
Beerens, H. C., Zwakhalen, S. M. G., Verbeek, H., Ruwaard, D. and Hamers, J. P. H. (2013). Factors associated with quality of life of people with dementia in long-term care facilities: a systematic review. International Journal of Nursing Studies, 50, 1259–1270.CrossRefGoogle ScholarPubMed
Beerens, H. C. et al. (2014). Quality of life of and quality of care for people with dementia receiving long-term institutional care or professional home care: the European RightTimePlaceCare study. Journal of the American Medical Directors Association, 15, 54–61.CrossRefGoogle ScholarPubMed
Bronnick, K., Ehrt, U., De Deyn, P. P., Wesnes, K., Tekin, S. and Aarsland, D. (2006). Attentional deficits affect activities of daily living in dementia-associated with Parkinson's disease. Journal of Neurology, Neurosurgery and Psychiatry, 77, 1136–1142.CrossRefGoogle ScholarPubMed
Buckley, T. et al. (2012). Predictors of quality of life ratings with dementia simultaneously reported by patients and their caregivers: the Cache County (Utah) study. International Psychogeriatrics, 24, 1094–1102.CrossRefGoogle ScholarPubMed
Conde-Sala, J. L. et al. (2014). Severity of dementia, anosognosia, and depression in relation to the quality of life of patients with Alzheimer disease: discrepancies between patients and caregivers. The American Journal of Geriatric Psychiatry, 22, 138–147.CrossRefGoogle ScholarPubMed
Creighton, A. S., van der Ploeg, E. S. and O’Connor, D. W. (2013). A literature review of spaced-retrieval interventions: a direct memory intervention for people with dementia. International Psychogeriatrics, 25, 1743–1763.CrossRefGoogle ScholarPubMed
Crespo, M., Hornillos, C. and Gomez, M. M. (2013). Assessing quality of life of nursing home residents with dementia: feasibility and limitations in patients with severe cognitive impairment. International Psychogeriatrics, 25, 1687–1695.CrossRefGoogle ScholarPubMed
Department of Health (2009). Living Well With Dementia. A National Dementia Strategy. London: Department of Health.Google Scholar
Earnst, K. S. et al. (2001). Loss of financial capacity in Alzheimer's disease: the role of working memory. Aging, Neuropsychology, and Cognition, 8, 109–119.Google Scholar
Folstein, M., Folstein, S. and McHugh, P. (1975). “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189–198.CrossRefGoogle Scholar
Galasko, D. et al. (2005). Detailed assessment of activities of daily living in moderate to severe Alzheimer's disease. Journal of the International Neuropsychological Society, 11, 446–453.CrossRefGoogle ScholarPubMed
Hoe, J., Hancock, G., Livingston, G. and Orrell, M. (2006). Quality of life of people with dementia in residential care homes. The British Journal of Psychiatry, 188, 460–464.CrossRefGoogle ScholarPubMed
Katz, S., Ford, A. B., Moskowitz, R. W., Jackson, B. A. and Jaffe, M. W. (1963). Studies of illness in the aged: the index of ADL: a standardized measure of biological and psychosocial function. JAMA: Journal of the American Medical Association, 185, 914–919.CrossRefGoogle Scholar
Kaufer, D. I. et al. (2000). Validation of the NPI-Q, a brief clinical form of the Neuropsychiatric Inventory. The Journal of Neuropsychiatry and Clinical Neurosciences, 12, 233–239.CrossRefGoogle ScholarPubMed
Knapp, M., Comas-Herrera, A., Somani, A. and Banerjee, S. (2007). Dementia: International Comparisons. London: Personal Social Services Research Unit.Google Scholar
LaPlante, M. P. (2010). The classic measure of disability in activities of daily living is biased by age but an expanded IADL/ADL measure is not. Journal of Gerontology: Social Sciences, 65B, 720–732.CrossRefGoogle Scholar
Lawton, M. P. and Brody, E. M. (1969). Assessment of older people: self-maintaining and instrumental activities of daily living. The Gerontologist, 9, 179–186.CrossRefGoogle ScholarPubMed
Lee, D. R., McKeith, I., Mosimann, U., Ghosh-Nodyal, A. and Thomas, A. J. (2013). Examining carer stress in dementia: the role of subtype diagnosis and neuropsychiatric symptoms. International Journal of Geriatric Psychiatry, 28, 135–141.CrossRefGoogle ScholarPubMed
Logsdon, R. G., Gibbons, L. E., McCurry, S. M. and Terri, L. (1999). Quality of life in Alzheimer's disease: patient and caregiver reports. Journal of Mental Health and Aging, 5, 21–32.Google Scholar
Ministry of Social Affairs and Health (2013). National Memory Programme 2012–2020. Creating a “Memory Friendly” Finland. Reports and Memorandum of the Ministry of Social Affairs 2013, 9, Helsinki, Finland. Available at: http://www.alzheimer-europe.org/Policy-in-Practice2/National-Dementia-Plans/Finland#-1; last accessed 16 April 2014.Google Scholar
Mioshi, E., Kipps, C. M., Dawson, K., Mitchell, J., Graham, A. and Hodges, J. R. (2007). Activities of daily living in frontotemporal dementia and Alzheimer disease. Neurology, 68, 2077–2084.CrossRefGoogle ScholarPubMed
Moyle, W., Murfield, J. E., Griffiths, S. G. and Venturato, L. (2012). Assessing quality of life of older people with dementia: a comparison of quantitative self-report and proxy accounts. Journal of Advanced Nursing, 68, 2237–2246.CrossRefGoogle ScholarPubMed
National Institute for Health and Clinical Excellence (NICE). (2006). Final Appraisal Determination: Donepezil, Galantamine, Rivastagmine (Review) and Memantine for the Treatment of Alzheimer's Disease. London: Department of Health.Google Scholar
Nestor, P. J., Fryer, T. D. and Hodges, J. R. (2006). Declarative memory impairments in Alzheimer's disease and semantic dementia. NeuroImage, 30, 1010–1020.CrossRefGoogle ScholarPubMed
Ostbye, T., Tyas, S., McDowell, I. and Koval, J. (1997). Reported activities of daily living: agreement between elderly subjects with and without dementia and their caregivers. Age and Ageing, 26, 99–106.CrossRefGoogle ScholarPubMed
Pizzi, M. et al. (2013). Physical barriers and risks in basic activities of daily living performance evaluation in state housing for older people in Chile. Housing, Care and Support, 16, 23–31.CrossRefGoogle Scholar
Pocnet, C., Rossier, J., Antonietti, J.-P. and von Gunten, A. (2013). Personality features and cognitive level in patients at an early stage of Alzheimer's disease. Personality and Individual Differences, 54, 174–179.CrossRefGoogle Scholar
Razani, J., Casas, R., Wong, J. T., Lu, P., Alessi, C. and Josephson, K. (2007). Relationship between executive functioning and activities of daily living in patients with relatively mild dementia. Applied Neuropsychology, 14, 208–214.CrossRefGoogle ScholarPubMed
Reisberg, B. et al. (1984). Functional staging of dementia of the Alzheimer's type. Annals of the New York Academy of Sciences, 435, 481–483.CrossRefGoogle Scholar
Republique Francaise (2008). National Plan for “Alzheimer and Related Diseases” 2008–2012. Available at: http://www.plan-alzheimer.gouv.fr/IMG/pdf/Plan_Alzheimer_2008-2012_uk.pdf; last accessed 16 April 2014.Google Scholar
Sclan, S. G. and Reisberg, B. (1992). Functional Assessment Staging (FAST) in Alzheimer's disease: reliability, validity, and ordinality. International Psychogeriatrics, 4 (Suppl. 1), 55–69.CrossRefGoogle ScholarPubMed
Seidel, D., Brayne, C. and Jagger, C. (2011). Limitations in physical functioning among older people as a predictor of subsequent disability in instrumental activities of daily living. Age and Ageing, 40, 463–469.CrossRefGoogle ScholarPubMed
Thorgrimsen, L. et al. (2003). Whose quality of life is it anyway?: the validity and reliability of the quality of life-Alzheimer's disease (QoL-AD) Scale. Alzheimer Disease & Associated Disorders, 17, 201–208.CrossRefGoogle ScholarPubMed
Tombaugh, T. N. and McIntyre, N. J. (1992). The Mini-Mental State Examination: a comprehensive review. Journal of the American Geriatrics Society, 40, 922–935.CrossRefGoogle ScholarPubMed
Verbeek, H. et al. (2012). A European study investigating patterns of transition from home care towards institutional dementia care: the protocol of a RightTimePlaceCare study. BMC Public Health, 12, 68.CrossRefGoogle Scholar