Chandler, M. J. Parks, A. C. Marsiske, M. Rotblatt, L. J. and Smith, G. E. 2016. Everyday Impact of Cognitive Interventions in Mild Cognitive Impairment: a Systematic Review and Meta-Analysis. Neuropsychology Review, Vol. 26, Issue. 3, p. 225.
García-Casal, J. Antonio Loizeau, Andrea Csipke, Emese Franco-Martín, Manuel Perea-Bartolomé, M. Victoria and Orrell, Martin 2016. Computer-based cognitive interventions for people living with dementia: a systematic literature review and meta-analysis. Aging & Mental Health, p. 1.
Middelstädt, Jennifer Folkerts, Ann-Kristin Blawath, Sabrina and Kalbe, Elke 2016. Cognitive Stimulation for People with Dementia in Long-Term Care Facilities: Baseline Cognitive Level Predicts Cognitive Gains, Moderated by Depression. Journal of Alzheimer's Disease, Vol. 54, Issue. 1, p. 253.
Toh, Hui Moon Ghazali, Shazli Ezzat and Subramaniam, Ponnusamy 2016. The Acceptability and Usefulness of Cognitive Stimulation Therapy for Older Adults with Dementia: A Narrative Review. International Journal of Alzheimer's Disease, Vol. 2016, p. 1.
Callahan, Christopher M. Tu, Wanzhu Stump, Timothy E. Clark, Daniel O. Unroe, Kathleen T. and Hendrie, Hugh C. 2015. Errors in Self-Reports of Health Services Use. Alzheimer Disease & Associated Disorders, Vol. 29, Issue. 1, p. 75.
Dawson, Alison Bowes, Alison Kelly, Fiona Velzke, Kari and Ward, Richard 2015. Evidence of what works to support and sustain care at home for people with dementia: a literature review with a systematic approach. BMC Geriatrics, Vol. 15, Issue. 1,
Fernández-Calvo, Bernardino Contador, Israel Ramos, Francisco Olazarán, Javier Mograbi, Daniel C. and Morris, Robin G. 2015. Effect of unawareness on rehabilitation outcome in a randomised controlled trial of multicomponent intervention for patients with mild Alzheimer's disease. Neuropsychological Rehabilitation, Vol. 25, Issue. 3, p. 448.
Huntley, J. D. Gould, R. L. Liu, K. Smith, M. and Howard, R. J. 2015. Do cognitive interventions improve general cognition in dementia? A meta-analysis and meta-regression. BMJ Open, Vol. 5, Issue. 4, p. e005247.
Rodakowski, Juleen Saghafi, Ester Butters, Meryl A. and Skidmore, Elizabeth R. 2015. Non-pharmacological interventions for adults with mild cognitive impairment and early stage dementia: An updated scoping review. Molecular Aspects of Medicine, Vol. 43-44, p. 38.
Vidovich, Mandy R. Lautenschlager, Nicola T. Flicker, Leon Clare, Linda McCaul, Kieran and Almeida, Osvaldo P. 2015. The PACE Study: A Randomized Clinical Trial of Cognitive Activity Strategy Training for Older People with Mild Cognitive Impairment. The American Journal of Geriatric Psychiatry, Vol. 23, Issue. 4, p. 360.
Lautenschlager, Nicola T. Anstey, Kaarin J. and Kurz, Alexander F. 2014. Non-pharmacological strategies to delay cognitive decline. Maturitas, Vol. 79, Issue. 2, p. 170.
Thivierge, Stéphanie Jean, Léonie and Simard, Martine 2014. A Randomized Cross-over Controlled Study on Cognitive Rehabilitation of Instrumental Activities of Daily Living in Alzheimer Disease. The American Journal of Geriatric Psychiatry, Vol. 22, Issue. 11, p. 1188.
Kurz, A. 2013. Psychosoziale Interventionen bei Demenz. Der Nervenarzt, Vol. 84, Issue. 1, p. 93.
Kurz, A. 2013. Psychosoziale Interventionen bei Demenz. Humanmedizin kompakt,
Kurz, Alexander Clare, Linda and Lautenschlager, Nicola T. 2013. Add life to years: psychosocial interventions for people with cognitive disorders. International Psychogeriatrics, Vol. 25, Issue. 09, p. 1389.
Mitchell, Meghan B. Cimino, Cynthia R. Benitez, Andreana Brown, Cassandra L. Gibbons, Laura E. Kennison, Robert F. Shirk, Steven D. Atri, Alireza Robitaille, Annie MacDonald, Stuart W. S. Lindwall, Magnus Zelinski, Elizabeth M. Willis, Sherry L. Schaie, K. Warner Johansson, Boo Dixon, Roger A. Mungas, Dan M. Hofer, Scott M. and Piccinin, Andrea M. 2012. Cognitively Stimulating Activities: Effects on Cognition across Four Studies with up to 21 Years of Longitudinal Data. Journal of Aging Research, Vol. 2012, p. 1.
Rockwood, Kenneth Zeng, An Leibman, Chris Mucha, Lisa and Mitnitski, Arnold 2012. Validation of an Informant-Reported Web-Based Data Collection to Assess Dementia Symptoms. Journal of Medical Internet Research, Vol. 14, Issue. 2, p. e42.
Ruthirakuhan, Myuri Luedke, Angela C. Tam, Angela Goel, Ankita Kurji, Ayaz and Garcia, Angeles 2012. Use of Physical and Intellectual Activities and Socialization in the Management of Cognitive Decline of Aging and in Dementia: A Review. Journal of Aging Research, Vol. 2012, p. 1.
Background: Cognitive stimulation, training or rehabilitation can achieve modest, skill-specific gains in cognitively healthy older adults. With regard to the limited efficacy of currently available anti-dementia drugs it is crucial to investigate whether such treatments also provide clinically meaningful benefits to cognitively impaired older individuals.
Methods: We conducted a systematic review of randomized controlled trials evaluating cognition-focused interventions in participants with mild cognitive impairment or dementia. Meta-analytic strategies were used to calculate effect sizes.
Results: Cognition-focused interventions confer small and inconsistent effects on trained cognitive skills which, according to some studies, translate into gains on general cognitive ability. Instruments measuring such effects such as the Mini-Mental State Examination (MMSE) or the Alzheimer's Disease Assessment Scale, cognitive part (ADAS-Cog) show standardized mean differences of 0.20 and 0.30, respectively, which are comparable with those of current antidementia drug treatments. However, convincing evidence of clinical significance was only obtained from single trials in terms of delay of cognitive decline, improvement in activities of daily living, or enhanced attainment of personally relevant goals.
Conclusions: The potential of cognition-focused interventions has probably been obscured by the methodological inconsistencies and limitations of the clinical studies conducted thus far. Further randomized controlled trials on the efficacy of these treatment modalities are required using optimized and consistent methods. Emphasis should be placed on tailoring interventions to individual needs and resources while maintaining a high level of standardization, on implementing newly acquired skills and strategies in the everyday context, on appropriate treatment duration, and on including person-centered outcomes.
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