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A rivastigmine-precipitated manic episode in a patient with Alzheimer-type dementia

Published online by Cambridge University Press:  26 April 2012

Wei-Shih Tseng  and
Nian-Sheng Tzeng
Wei-Shih Tseng
Affiliation:
Department of Diving Medicine, Zuoying Armed Forces General Hospital, Kaohsiung, Taiwan, ROC Department of Neurology, Tri-Service General Hospital, Taipei, Taiwan, ROC School of Medicine, National Defense Medical Center, Taipei, Taiwan, ROC
Nian-Sheng Tzeng*
Affiliation:
Department of Psychiatry, Tri-Service General Hospital, Taipei, Taiwan, ROC School of Medicine, National Defense Medical Center, Taipei, Taiwan, ROC Student Counseling Center, National Defense Medical Center, Taipei, Taiwan, ROC
*
Correspondence should be addressed to: Nian-Sheng Tzeng, MD, Clinical Assistant Professor and Attending Psychiatrist, Department of Psychiatry, Tri-Service General Hospital, National Defense Medical Center, No. 325, Section 2, Cheng-Kung Road, Neihu 114, Taipei, Taiwan, ROC. Phone: + 886-2-87923311, ext: 13674; Fax: + 886-2-87927221. Email: pierrens@mail.ndmctsgh.edu.tw.
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Abstract

The occurrence of mania in the geriatric population is rare. Furthermore, there were only six case reports of elderly patients with secondary mania resulting from treatment with cholinesterase inhibitors. In all cases, patients had a prior psychiatric history. We report the case of an elderly patient with no prior history of psychiatric or other organic disorders who experienced first episode mania following treatment with rivastigmine. We discuss the possible mechanism of mania in this patient.

Keywords

dementiarivastigminedonepezilmanic episodeChEIAChEBuChE
Type
Case Report
Information
International Psychogeriatrics , Volume 24 , Issue 10 , October 2012 , pp. 1697 - 1699
Copyright
Copyright © International Psychogeriatric Association 2012

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