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Patient-Centered Network of Learning Health Systems: Developing a resource for clinical translational research

  • L. J. Finney Rutten (a1) (a2), A. Alexander (a2), P. J. Embi (a3), G. Flores (a4), C. Friedman (a5), I. V. Haller (a6), P. Haug (a7), D. Jensen (a8), S. Khosla (a9) (a10), G. Runger (a11), N. D. Shah (a1) (a2), T. Winden (a12) and V. L. Roger (a1) (a2) (a13)...
Abstract
Introduction

The Learning Health System Network clinical data research network includes academic medical centers, health-care systems, public health departments, and health plans, and is designed to facilitate outcomes research, pragmatic trials, comparative effectiveness research, and evaluation of population health interventions.

Methods

The Learning Health System Network is 1 of 13 clinical data research networks assembled to create, in partnership with 20 patient-powered research networks, a National Patient-Centered Clinical Research Network.

Results and Conclusions

Herein, we describe the Learning Health System Network as an emerging resource for translational research, providing details on the governance and organizational structure of the network, the key milestones of the current funding period, and challenges and opportunities for collaborative science leveraging the network.

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Copyright
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Corresponding author
*Address for correspondence: L. J. Finney Rutten, Ph.D., M.P.H., Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. (Email: rutten.lila@mayo.edu)
Linked references
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This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

2. JV Selby , et al. Network news: powering clinical research. Science Translational Medicine 2013; 5: 182fs13.

3. DA Corley , et al. Building data infrastructure to evaluate and improve quality: PCORnet. Journal of Oncology Practice/American Society of Clinical Oncology 2015; 11: 204206.

4. FS Collins , et al. PCORnet: turning a dream into reality. Journal of the American Medical Informatics Association: JAMIA 2014; 21: 576577.

5. RL Fleurence , et al. Launching PCORnet, a National Patient-Centered Clinical Research Network. Journal of the American Medical Informatics Association: JAMIA 2014; 21: 578582.

7. CP Friedman , AK Wong , D Blumenthal . Achieving a nationwide learning health system. Science Translational Medicine 2010; 2: 57cm29.

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Journal of Clinical and Translational Science
  • ISSN: -
  • EISSN: 2059-8661
  • URL: /core/journals/journal-of-clinical-and-translational-science
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