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Effect of Irradiation on the Infective Stage Larvae of the Nematode, Oesophagostomum columbianum and their Use as a Vaccine
Published online by Cambridge University Press: 05 June 2009
Extract
The effect of irradiation on the survival, behaviour and immunogenicity of the infective (3rd stage) larvae of O. columbianum was studied. The findings reported are:
1. Irradiation with up to 160,000 r does not significantly alter the survival of the larvae when stored at 4°C and at room temperature (26–32°C) for a period of 42 days.
2. Irradiation at 15.000 r to 40,000 r results in progressively fewer adults developing but more nodules being formed in the intestinal wall. Irradiation at 80,000 r results in the larvae failing to develop and establish in the host.
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- Copyright © Cambridge University Press 1970
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