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Aetiology of recurrent aphthous ulcers (RAU)

  • Monir Maurice (a1), Wadie Mikhail (a2), Medhat Aziz (a3) and Maged Barsoum (a4)


A significant decrease in the pH of saliva has been detected in patients with recurrent aphthous ulcers (RAU). The decreae in pH was more prominent at night than between meals, and some persistent decrease was noticed even after recovery. The total proteins of saliva in RAU were also significantly decreased.

These findings were similar to those observed in patients complaining of petic ulcers, so it is recommended that patients with RAU should be treated with antacids as well as anticholinergic drugs, and that the possibility of concomitant peptic ulceration should also be investigated.


Corresponding author

Dr. Monir Maurice, M.D., E.N.T. Head of E.N.T. Section, El-Sahel Teaching Hospital, Shoubra, Cairo, Egypt.


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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
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